IL97656A - History of 1,3-dipropyl-8-aralkyl xanthine, the process for their preparation and medicinal preparations containing them - Google Patents

History of 1,3-dipropyl-8-aralkyl xanthine, the process for their preparation and medicinal preparations containing them

Info

Publication number: IL97656A
Authority: IL; Israel
Prior art keywords: dione; dihydro; dipropyl; compound according; purine
Prior art date: 1990-03-26

Application number

IL9765691A

Other languages

English (en)

Hebrew (he)

Other versions

IL97656A0 (en

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-26

Filing date

1991-03-22

Publication date

1996-06-18

1991-03-22 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1992-06-21 Publication of IL97656A0 publication Critical patent/IL97656A0/xx

1996-06-18 Publication of IL97656A publication Critical patent/IL97656A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL9765691A 1990-03-26 1991-03-22 History of 1,3-dipropyl-8-aralkyl xanthine, the process for their preparation and medicinal preparations containing them IL97656A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/499,111 US5047534A (en)	1990-03-26	1990-03-26	Selective adenosine receptor agents

Publications (2)

Publication Number	Publication Date
IL97656A0 IL97656A0 (en)	1992-06-21
IL97656A true IL97656A (en)	1996-06-18

Family

ID=23983864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9765691A IL97656A (en)	1990-03-26	1991-03-22	History of 1,3-dipropyl-8-aralkyl xanthine, the process for their preparation and medicinal preparations containing them

Country Status (22)

Country	Link
US (1)	US5047534A (no)
EP (1)	EP0449175B1 (no)
JP (1)	JP3181305B2 (no)
KR (1)	KR100195368B1 (no)
CN (1)	CN1032815C (no)
AR (1)	AR247887A1 (no)
AT (1)	ATE156130T1 (no)
AU (1)	AU632914B2 (no)
CA (1)	CA2038747C (no)
DE (1)	DE69127010T2 (no)
DK (1)	DK0449175T3 (no)
ES (1)	ES2107431T3 (no)
FI (1)	FI98461C (no)
GR (1)	GR3025135T3 (no)
HU (1)	HU208824B (no)
IE (1)	IE910982A1 (no)
IL (1)	IL97656A (no)
NO (1)	NO177591C (no)
NZ (1)	NZ237484A (no)
PH (1)	PH27511A (no)
PT (1)	PT97133B (no)
ZA (1)	ZA912038B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5208240A (en) *	1991-03-12	1993-05-04	Merrell Dow Pharmaceuticals Inc.	8-substituted purines as selective adenosine receptor agents
CA2116967C (en) *	1992-07-08	2003-08-19	Fumio Suzuki	Antidepressants
ES2120025T3 (es) *	1993-02-26	1998-10-16	Merrell Pharma Inc	Derivados de xantina utilizados como antagonistas de receptores de adenosina a1.
AU6781194A (en) *	1993-05-03	1994-11-21	United States Of America, Represented By The Secretary, Department Of Health And Human Services, The	8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
WO1994026744A1 (en) *	1993-05-06	1994-11-24	Merrell Dow Pharmaceuticals Inc.	8-substituted xanthines as selective adenosine receptor agents
US5629298A (en) *	1995-03-13	1997-05-13	University Of Massachusetts Medical Center	Adenosine as a positive inotrop in the compromised heart
GB9819382D0 (en)	1998-09-04	1998-10-28	Cerebrus Ltd	Chemical compounds I
US6258794B1 (en)	1999-12-14	2001-07-10	The Mclean Hospital Corporation	Treatment of mental conditions including depression
ATE481101T1 (de) *	2003-06-10	2010-10-15	Kyowa Hakko Kirin Co Ltd	Verfahren zur behandlung von angstzuständen
WO2007036491A1 (de) *	2005-09-30	2007-04-05	Basf Aktiengesellschaft	Verfahren zur herstellung von alpha-substituierten carbonsäuren
US7592461B2 (en) *	2005-12-21	2009-09-22	Bristol-Myers Squibb Company	Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
KR102060903B1 (ko) *	2018-09-12	2019-12-30	김지훈	다중접합 도마 및 그 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1435916A (en) *	1972-05-11	1976-05-19	Beecham Group Ltd	Pharmaceutical weight-reducing compositions
SE416810C (sv) *	1977-10-14	1982-07-19	Draco Ab	Forfarande for framstellning av xantinderivat med antiallergisk aktivitet
JPS57198544A (en) *	1981-05-28	1982-12-06	Sony Corp	Manufacture of magnetic recording medium
US4593095A (en) *	1983-02-18	1986-06-03	The Johns Hopkins University	Xanthine derivatives
US4772607A (en) *	1986-05-20	1988-09-20	Warner-Lambert Company	Dialkenyl derivatives of xanthine, pharmaceutical compositions and methods of use therefor
US4783530A (en) *	1986-11-13	1988-11-08	Marion Laboratories, Inc.	8-arylxanthines
DE8817122U1 (de) *	1988-12-22	1993-02-04	Boehringer Ingelheim Kg, 55218 Ingelheim	Neue Xanthinderivate mit Adenosinantogenistischer Wirkung

1990
- 1990-03-26 US US07/499,111 patent/US5047534A/en not_active Expired - Fee Related
1991
- 1991-03-19 ZA ZA912038A patent/ZA912038B/xx unknown
- 1991-03-19 AU AU73537/91A patent/AU632914B2/en not_active Ceased
- 1991-03-19 NZ NZ237484A patent/NZ237484A/xx unknown
- 1991-03-20 AR AR91319262A patent/AR247887A1/es active
- 1991-03-21 CA CA002038747A patent/CA2038747C/en not_active Expired - Fee Related
- 1991-03-22 IL IL9765691A patent/IL97656A/en not_active IP Right Cessation
- 1991-03-22 PH PH42193A patent/PH27511A/en unknown
- 1991-03-25 EP EP91104668A patent/EP0449175B1/en not_active Expired - Lifetime
- 1991-03-25 NO NO911200A patent/NO177591C/no not_active IP Right Cessation
- 1991-03-25 KR KR1019910004660A patent/KR100195368B1/ko not_active IP Right Cessation
- 1991-03-25 CN CN91101892A patent/CN1032815C/zh not_active Expired - Fee Related
- 1991-03-25 AT AT91104668T patent/ATE156130T1/de not_active IP Right Cessation
- 1991-03-25 DK DK91104668.8T patent/DK0449175T3/da active
- 1991-03-25 PT PT97133A patent/PT97133B/pt not_active IP Right Cessation
- 1991-03-25 HU HU91985A patent/HU208824B/hu not_active IP Right Cessation
- 1991-03-25 IE IE098291A patent/IE910982A1/en not_active IP Right Cessation
- 1991-03-25 FI FI911420A patent/FI98461C/fi active
- 1991-03-25 ES ES91104668T patent/ES2107431T3/es not_active Expired - Lifetime
- 1991-03-25 DE DE69127010T patent/DE69127010T2/de not_active Expired - Fee Related
- 1991-03-26 JP JP08451291A patent/JP3181305B2/ja not_active Expired - Fee Related
1997
- 1997-10-22 GR GR970402767T patent/GR3025135T3/el unknown

Also Published As

Publication number	Publication date
CA2038747A1 (en)	1991-09-27
IL97656A0 (en)	1992-06-21
KR100195368B1 (ko)	1999-06-15
ES2107431T3 (es)	1997-12-01
PT97133A (pt)	1991-12-31
NO911200L (no)	1991-09-27
CN1055181A (zh)	1991-10-09
FI911420A0 (fi)	1991-03-25
NO177591B (no)	1995-07-10
PH27511A (en)	1993-08-18
CN1032815C (zh)	1996-09-18
AU7353791A (en)	1991-10-03
AR247887A1 (es)	1995-04-28
PT97133B (pt)	1998-07-31
HU208824B (en)	1994-01-28
IE910982A1 (en)	1991-10-09
HUT56570A (en)	1991-09-30
EP0449175B1 (en)	1997-07-30
GR3025135T3 (en)	1998-02-27
EP0449175A2 (en)	1991-10-02
ATE156130T1 (de)	1997-08-15
JP3181305B2 (ja)	2001-07-03
NO177591C (no)	1995-10-18
AU632914B2 (en)	1993-01-14
FI98461B (fi)	1997-03-14
EP0449175A3 (en)	1993-01-20
NO911200D0 (no)	1991-03-25
DE69127010D1 (de)	1997-09-04
DK0449175T3 (da)	1998-02-23
JPH04221384A (ja)	1992-08-11
CA2038747C (en)	2002-05-28
FI98461C (fi)	1997-06-25
DE69127010T2 (de)	1997-11-13
US5047534A (en)	1991-09-10
FI911420A (fi)	1991-09-27
ZA912038B (en)	1991-12-24
NZ237484A (en)	1993-10-26
KR910016752A (ko)	1991-11-05

Publication	Publication Date	Title
CA2024381C (en)	1997-01-07	Xanthine compounds
EP0203721A2 (en)	1986-12-03	8-Phenyl xanthines
CA2344828A1 (en)	2000-03-30	¬1,2,4\|triazolo¬1,5-c\|pyrimidine derivatives
US5047534A (en)	1991-09-10	Selective adenosine receptor agents
CA2155130C (en)	1994-09-01	Xanthine derivatives as adenosine a1 receptor antagonists
JP2954971B2 (ja)	1999-09-27	選択的アデノシン受容体剤
US5734052A (en)	1998-03-31	8-substituted xanthines as selective adenosine receptor agents
US5064947A (en)	1991-11-12	Selective adenosine reseptor compounds
EP0662975B1 (en)	1997-03-26	2-substituted adenosines with a-2 receptor affinity
EP0390111B1 (en)	1994-09-14	Selective adenosine receptor compounds
US5426101A (en)	1995-06-20	2-substituted adenosines with A-2 receptor affinity
US5086176A (en)	1992-02-04	Tricyclic fused adenine derivatives

Legal Events

Date	Code	Title
1996-11-14	FF	Patent granted
1997-03-18	KB	Patent renewed
1997-06-10	KB	Patent renewed
2001-07-24	KB	Patent renewed
2006-01-15	MM9K	Patent not in force due to non-payment of renewal fees