[go: up one dir, main page]

IL95045A0 - Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL95045A0
IL95045A0 IL95045A IL9504590A IL95045A0 IL 95045 A0 IL95045 A0 IL 95045A0 IL 95045 A IL95045 A IL 95045A IL 9504590 A IL9504590 A IL 9504590A IL 95045 A0 IL95045 A0 IL 95045A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
thienodiazepine
derivatives
Prior art date
Application number
IL95045A
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of IL95045A0 publication Critical patent/IL95045A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/49Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with carbon monoxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL95045A 1989-07-12 1990-07-11 Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them IL95045A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3922944 1989-07-12
DE4011345 1990-04-07

Publications (1)

Publication Number Publication Date
IL95045A0 true IL95045A0 (en) 1991-06-10

Family

ID=25882911

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95045A IL95045A0 (en) 1989-07-12 1990-07-11 Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
EP (1) EP0407955A1 (en)
JP (1) JPH03215489A (en)
KR (1) KR910002863A (en)
AU (1) AU636155B2 (en)
CA (1) CA2020806A1 (en)
FI (1) FI903509A0 (en)
HU (1) HUT59144A (en)
IE (1) IE902526A1 (en)
IL (1) IL95045A0 (en)
NO (1) NO903088L (en)
NZ (1) NZ234476A (en)
PL (1) PL286019A1 (en)
PT (1) PT94673A (en)
YU (1) YU133090A (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95708C (en) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogous process for preparing a 1,4-diazepine derivative and its pharmaceutically acceptable salt
DE4027470A1 (en) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg NEW HETRAZEPINOIDE AMIDE
DE4101146A1 (en) * 1991-01-16 1992-07-23 Boehringer Ingelheim Kg NEW DIAZEPINE SUBSTITUTED IN 6-POSITION, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICAMENT
DE4107521A1 (en) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg NEW ACYLAMINOSUBSTITUTED HETRAZEPINE
CA2265645C (en) * 1996-09-13 2007-01-23 Yoshitomi Pharmaceutical Industries Ltd. Thienotriazolodiazepine compounds and pharmaceutical use thereof
US5939432A (en) 1997-10-29 1999-08-17 Medco Research, Inc. Thiophenes useful for modulating the adenosine receptor
US6727258B2 (en) 1997-10-29 2004-04-27 King Pharmaceutical Research & Development, Inc. Allosteric adenosine receptor modulators
US6323214B1 (en) 1997-10-29 2001-11-27 Medco Research, Inc Allosteric adenosine receptor modulators
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
JP5008796B2 (en) * 2001-01-19 2012-08-22 ダイト株式会社 Method for producing aromatic carboxylic acid
WO2006129623A1 (en) * 2005-05-30 2006-12-07 Mitsubishi Tanabe Pharma Corporation Thienotriazolodiazepine compound and a medicinal use thereof
CA2799381A1 (en) 2010-05-14 2011-11-17 Dana-Farber Cancer Institute, Inc. Male contraceptive compositions and methods of use
ES2534521T3 (en) 2010-05-14 2015-04-23 Dana-Farber Cancer Institute, Inc. Compositions and their use in the treatment of neoplasia, inflammatory diseases and other diseases
CN103154246B (en) 2010-05-14 2015-11-25 达那-法伯癌症研究所 Be used for the treatment of leukemic composition and method
WO2012075456A1 (en) 2010-12-02 2012-06-07 Constellation Pharmaceuticals Bromodomain inhibitors and uses thereof
AR084070A1 (en) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc BROMODOMINIUM INHIBITORS AND USES OF THE SAME
WO2012151512A2 (en) 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9328117B2 (en) 2011-06-17 2016-05-03 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
EP2864336B1 (en) 2012-06-06 2016-11-23 Constellation Pharmaceuticals, Inc. Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (en) 2012-06-06 2017-10-21 星宿藥物公司 Bromodomain inhibitors and uses thereof
US9975896B2 (en) 2013-07-25 2018-05-22 Dana-Farber Cancer Institute, Inc. Inhibitors of transcription factors and uses thereof
JP6637884B2 (en) 2013-11-08 2020-01-29 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド Combination therapy for cancer using bromodomain and extra terminal (BET) protein inhibitors
JP2017504653A (en) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド Diaminopyrimidine benzenesulfone derivatives and uses thereof
EP3099693A4 (en) 2014-01-31 2017-08-16 Dana-Farber Cancer Institute, Inc. Uses of diazepane derivatives
MX2016011160A (en) 2014-02-28 2017-04-27 Tensha Therapeutics Inc Treatment of conditions associated with hyperinsulinaemia.
TR201906788T4 (en) 2014-06-20 2019-05-21 Constellation Pharmaceuticals Inc Crystal forms of 2 - ((4s) -6- (4-chlorophenyl) -1-methyl-4h-benzo [c] isoxazolo [4,5-e] azepin-4-yl) acetamide.
KR20170032474A (en) 2014-08-08 2017-03-22 다나-파버 캔서 인스티튜트 인크. Dihydropteridinone derivatives and uses thereof
BR112017002369A2 (en) 2014-08-08 2017-12-05 Dana Farber Cancer Inst Inc diazepan derivatives and uses thereof
CA2965330A1 (en) 2014-10-27 2016-05-06 Tensha Therapeutics, Inc. Bromodomain inhibitors
AU2016276963C1 (en) 2015-06-12 2021-08-05 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
CR20180199A (en) 2015-09-11 2018-05-25 Dana Farber Cancer Inst Inc ACETAMIDE TIENOTRIAZOLODIAZEPINAS AND USES OF THE SAME
KR20180049058A (en) 2015-09-11 2018-05-10 다나-파버 캔서 인스티튜트 인크. Cyanothienotriazolodiazepines and their uses
JP7385356B2 (en) 2015-11-25 2023-11-22 ダナ-ファーバー キャンサー インスティテュート, インコーポレイテッド Divalent bromodomain inhibitors and their uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2712951A1 (en) * 1977-03-24 1978-10-05 Bosch Gmbh Robert BIMETAL WITH AN ELECTRIC HEATING ELEMENT
DE3701344A1 (en) * 1986-01-21 1987-07-23 Boehringer Ingelheim Kg NEW THIENO-1,4-DIAZEPINE
EP0230942B1 (en) * 1986-01-21 1992-04-29 Boehringer Ingelheim Kg Thieno-1,4-diazepines
DE3610848A1 (en) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg NEW 1,4-DIAZEPINE
DE3624779C2 (en) * 1986-07-22 1996-03-07 Boehringer Ingelheim Kg Process for the preparation of thieno-triazolo-1,4-diazepino-2-carboxylic acid amides
DE3724031A1 (en) * 1986-07-22 1988-01-28 Boehringer Ingelheim Kg NEW HETRAZEPINES AND METHOD FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
KR910002863A (en) 1991-02-26
JPH03215489A (en) 1991-09-20
IE902526A1 (en) 1991-02-13
CA2020806A1 (en) 1991-01-13
YU133090A (en) 1993-10-20
NO903088D0 (en) 1990-07-11
NZ234476A (en) 1992-08-26
PL286019A1 (en) 1991-10-21
HUT59144A (en) 1992-04-28
FI903509A0 (en) 1990-07-11
AU5892490A (en) 1991-01-17
AU636155B2 (en) 1993-04-22
EP0407955A1 (en) 1991-01-16
PT94673A (en) 1991-03-20
HU904169D0 (en) 1990-12-28
NO903088L (en) 1991-01-14

Similar Documents

Publication Publication Date Title
IL95045A0 (en) Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL91129A0 (en) Aminomethyloxooxazolidinyl arylbenzene derivatives,their preparation and pharmaceutical compositions containing them
IL90245A0 (en) Ethenediamine derivatives,their preparation and pharmaceutical compositions containing them
IL95155A0 (en) 1h-indazole-3-carboxamides,their preparation and pharmaceutical compositions containing them
IL95640A0 (en) 1-cycloalkylpiperidines,their preparation and pharmaceutical compositions containing them
IL99225A0 (en) 3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL96385A0 (en) Indole derivatives,their preparation and pharmaceutical compositions containing them
IL96516A0 (en) Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL100262A0 (en) Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them
IL94556A0 (en) Hydroxypropylamines,their preparation and pharmaceutical compositions containing them
IL94082A0 (en) 3-n-substituted carbamoyl-indole derivatives,their preparation and pharmaceutical compositions containing them
IL97050A0 (en) 4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation
IL98542A0 (en) Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL93124A0 (en) Benzocycloalkenyldihydroxyalkanoic-acid derivatives,their preparation and pharmaceutical compositions
IL88989A (en) 16-dehydro-vitamin d3 derivatives, their preparation and pharmaceutical compositions containing them
IL96384A0 (en) Pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL92710A0 (en) 2-iminobenzothiazoline derivatives,their preparation and pharmaceutical compositions containing them
IL91245A0 (en) Benzopyranol derivatives,their preparation and pharmaceutical compositions containing them
IL90002A0 (en) Phosphonoalkylpurine derivatives,their preparation and pharmaceutical compositions containing them
IL91709A0 (en) Substituted thienopyrans,their preparation and pharmaceutical compositions containing them
IL92326A0 (en) Substituted oxadiamino-butanes,their preparation and pharmaceutical compositions containing them
IL96252A0 (en) Pyridine derivatives,their preparation and pharmaceutical compositions containing them
ZA912975B (en) Serotonin-antagonist naphthosultam derivatives,their preparation and pharmaceutical compositions containing them
IL96216A0 (en) Peptide derivatives,their preparation and pharmaceutical compositions containing them
IL93750A0 (en) Tetrahydronaphthalene derivatives,their preparation and pharmaceutical compositions containing them