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IL84452A - 2-amino-5-aryloxy-cyclopentanols - Google Patents

2-amino-5-aryloxy-cyclopentanols

Info

Publication number
IL84452A
IL84452A IL84452A IL8445284A IL84452A IL 84452 A IL84452 A IL 84452A IL 84452 A IL84452 A IL 84452A IL 8445284 A IL8445284 A IL 8445284A IL 84452 A IL84452 A IL 84452A
Authority
IL
Israel
Prior art keywords
cyclopentanols
aryloxy
amino
Prior art date
Application number
IL84452A
Other languages
English (en)
Other versions
IL84452A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL84452A0 publication Critical patent/IL84452A0/xx
Publication of IL84452A publication Critical patent/IL84452A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/75Reactions with formaldehyde
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
IL84452A 1983-05-25 1984-05-22 2-amino-5-aryloxy-cyclopentanols IL84452A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49777583A 1983-05-25 1983-05-25
IL71891A IL71891A (en) 1983-05-25 1984-05-22 Aryloxycycloalkanolamino-alkyl aryl ketones,pharmaceutical compositions comprising them and process for the preparation of some such compounds

Publications (2)

Publication Number Publication Date
IL84452A0 IL84452A0 (en) 1988-04-29
IL84452A true IL84452A (en) 1991-03-10

Family

ID=23978256

Family Applications (3)

Application Number Title Priority Date Filing Date
IL84452A IL84452A (en) 1983-05-25 1984-05-22 2-amino-5-aryloxy-cyclopentanols
IL84454A IL84454A (en) 1983-05-25 1984-05-22 Exocyclic methylene ketones
IL71891A IL71891A (en) 1983-05-25 1984-05-22 Aryloxycycloalkanolamino-alkyl aryl ketones,pharmaceutical compositions comprising them and process for the preparation of some such compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL84454A IL84454A (en) 1983-05-25 1984-05-22 Exocyclic methylene ketones
IL71891A IL71891A (en) 1983-05-25 1984-05-22 Aryloxycycloalkanolamino-alkyl aryl ketones,pharmaceutical compositions comprising them and process for the preparation of some such compounds

Country Status (19)

Country Link
EP (1) EP0127143B1 (pt)
JP (1) JPS59231047A (pt)
KR (1) KR890000021B1 (pt)
AR (1) AR241900A1 (pt)
AT (1) ATE51148T1 (pt)
AU (3) AU566534B2 (pt)
CA (1) CA1263656C (pt)
DE (1) DE3481683D1 (pt)
DK (1) DK256484A (pt)
ES (2) ES8507530A1 (pt)
GR (1) GR82032B (pt)
HU (1) HU200440B (pt)
IE (1) IE57535B1 (pt)
IL (3) IL84452A (pt)
NO (1) NO169588C (pt)
NZ (3) NZ223185A (pt)
PH (3) PH24747A (pt)
PT (1) PT78638A (pt)
ZA (1) ZA843836B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH24747A (en) * 1983-05-25 1990-10-01 Merrell Dow Pharma Novel aryloxycycloalkanolaminoalkylene aryl ketons and method of use thereof
CA1338868C (en) * 1988-04-25 1997-01-21 Theophilus F. Leapheart Process for the production of cis-hydroxy trans-phenoxycyclopentylamines
US5214169A (en) * 1988-04-25 1993-05-25 Merrell Dow Pharmaceuticals Inc. N-(2,3-epoxycyclopentyl) carbamate derivatives
DE3840802A1 (de) * 1988-11-29 1990-05-31 Schering Ag 2-hydroxymethylthiophen-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB249261A (en) * 1925-01-22 1926-03-25 Gen Electric Co Ltd Improvements in or relating to overspeed and overwinding gears for winding engines
DE1913199C3 (de) * 1969-03-15 1975-11-27 Beiersdorf Ag, 2000 Hamburg Mannichbasen aus alpha-Tetralon bzw. dessen Derivaten und Arylalkylaminen und deren Salze
DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
PH24747A (en) * 1983-05-25 1990-10-01 Merrell Dow Pharma Novel aryloxycycloalkanolaminoalkylene aryl ketons and method of use thereof

Also Published As

Publication number Publication date
HU200440B (en) 1990-06-28
CA1263656A (en) 1989-12-05
ATE51148T1 (de) 1990-04-15
IL84452A0 (en) 1988-04-29
CA1263656C (en) 1989-12-05
DE3481683D1 (de) 1990-04-26
PT78638A (en) 1984-06-01
IL84454A0 (en) 1988-04-29
IL71891A0 (en) 1984-09-30
PH23216A (en) 1989-06-06
AU608768B2 (en) 1991-04-18
AU2851684A (en) 1984-11-29
PH23191A (en) 1989-05-29
KR840009094A (ko) 1984-12-24
ES536397A0 (es) 1985-11-01
IE57535B1 (en) 1992-10-07
AU7761687A (en) 1987-12-03
JPS59231047A (ja) 1984-12-25
GR82032B (pt) 1984-12-12
EP0127143A2 (en) 1984-12-05
ZA843836B (en) 1984-12-24
DK256484D0 (da) 1984-05-24
NO842078L (no) 1984-11-26
IL71891A (en) 1991-03-10
JPH0530824B2 (pt) 1993-05-11
IL84454A (en) 1991-03-10
AU593679B2 (en) 1990-02-15
AR241900A1 (es) 1993-01-29
EP0127143B1 (en) 1990-03-21
ES8601849A1 (es) 1985-11-01
KR890000021B1 (ko) 1989-03-06
ES532777A0 (es) 1985-09-01
AU7761787A (en) 1987-12-03
AU566534B2 (en) 1987-10-22
EP0127143A3 (en) 1985-05-29
NZ223185A (en) 1989-07-27
NZ223184A (en) 1989-07-27
DK256484A (da) 1984-11-26
PH24747A (en) 1990-10-01
NO169588C (no) 1992-07-15
HUT36091A (en) 1985-08-28
ES8507530A1 (es) 1985-09-01
NZ208230A (en) 1989-07-27
NO169588B (no) 1992-04-06
IE841297L (en) 1984-11-25

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Legal Events

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KB Patent renewed
EXP Patent expired
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.