IL84261A - Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor - Google Patents
Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitorInfo
- Publication number
- IL84261A IL84261A IL84261A IL8426187A IL84261A IL 84261 A IL84261 A IL 84261A IL 84261 A IL84261 A IL 84261A IL 8426187 A IL8426187 A IL 8426187A IL 84261 A IL84261 A IL 84261A
- Authority
- IL
- Israel
- Prior art keywords
- thromboxane
- diphenyl
- pharmaceutical compositions
- synthetase inhibitor
- dioxane derivative
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- TUJMFENFEJTHDG-UHFFFAOYSA-N 2,4-diphenyl-1,3-dioxane Chemical class O1CCC(C=2C=CC=CC=2)OC1C1=CC=CC=C1 TUJMFENFEJTHDG-UHFFFAOYSA-N 0.000 title 1
- 108010069102 Thromboxane-A synthase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- DSNBHJFQCNUKMA-SCKDECHMSA-N thromboxane A2 Chemical compound OC(=O)CCC\C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)O[C@@H]2O[C@H]1C2 DSNBHJFQCNUKMA-SCKDECHMSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940127293 prostanoid Drugs 0.000 abstract 1
- 150000003814 prostanoids Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868626297A GB8626297D0 (en) | 1986-11-04 | 1986-11-04 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL84261A true IL84261A (en) | 1991-12-15 |
Family
ID=10606757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL84261A IL84261A (en) | 1986-11-04 | 1987-10-23 | Pharmaceutical compositions comprising a 2,4-diphenyl 1,3-dioxane derivative and a thromboxane a2 synthetase inhibitor |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4908380A (da) |
| EP (1) | EP0266980B1 (da) |
| JP (1) | JPS63130532A (da) |
| AT (1) | ATE81774T1 (da) |
| AU (1) | AU608546B2 (da) |
| CA (1) | CA1308660C (da) |
| DE (1) | DE3782396T2 (da) |
| DK (1) | DK576887A (da) |
| ES (1) | ES2052581T3 (da) |
| GB (1) | GB8626297D0 (da) |
| GR (1) | GR3006099T3 (da) |
| IL (1) | IL84261A (da) |
| ZA (1) | ZA877886B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8901201D0 (en) * | 1988-02-16 | 1989-03-15 | Ici Plc | Pyridine derivatives |
| US5248780A (en) * | 1988-02-16 | 1993-09-28 | Imperial Chemical Industries, Plc | Pyridyl substituted alkenoic acid derivatives |
| GB9021571D0 (en) * | 1990-10-04 | 1990-11-21 | Ici Plc | Heterocyclic acids |
| CA2637803A1 (en) | 2006-01-18 | 2007-12-06 | Evolva Sa | Ppar modulators |
| WO2008089463A2 (en) | 2007-01-18 | 2008-07-24 | Evolva Sa | Substituted 1,3-dioxanes and their uses |
| US20120142766A1 (en) * | 2007-11-21 | 2012-06-07 | Evolva Sa | Substituted 1,3-dioxanes and their uses |
| AR072297A1 (es) | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2111050B (en) * | 1981-11-19 | 1985-09-11 | Ciba Geigy Ag | N-substituted-2-pyridylindoles |
| GB8310407D0 (en) * | 1982-05-12 | 1983-05-25 | Ici Plc | 1 3 - dioxan -5- ylalkenoic acids |
| GB8330120D0 (en) * | 1983-11-11 | 1983-12-21 | Ici Plc | Chemical process |
| GB8511890D0 (en) * | 1985-05-10 | 1985-06-19 | Ici Plc | Benzene derivatives |
| GB8619450D0 (en) * | 1986-08-08 | 1986-09-17 | Glaxo Group Ltd | Chemical compositions |
-
1986
- 1986-11-04 GB GB868626297A patent/GB8626297D0/en active Pending
-
1987
- 1987-10-20 ZA ZA877886A patent/ZA877886B/xx unknown
- 1987-10-23 IL IL84261A patent/IL84261A/xx not_active IP Right Cessation
- 1987-10-30 DE DE8787309635T patent/DE3782396T2/de not_active Expired - Fee Related
- 1987-10-30 ES ES87309635T patent/ES2052581T3/es not_active Expired - Lifetime
- 1987-10-30 EP EP87309635A patent/EP0266980B1/en not_active Expired - Lifetime
- 1987-10-30 AT AT87309635T patent/ATE81774T1/de not_active IP Right Cessation
- 1987-11-03 DK DK576887A patent/DK576887A/da not_active Application Discontinuation
- 1987-11-03 US US07/118,226 patent/US4908380A/en not_active Expired - Fee Related
- 1987-11-03 CA CA000550880A patent/CA1308660C/en not_active Expired - Fee Related
- 1987-11-04 JP JP62277555A patent/JPS63130532A/ja active Pending
- 1987-11-04 AU AU80698/87A patent/AU608546B2/en not_active Ceased
-
1992
- 1992-10-29 GR GR910402232T patent/GR3006099T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB8626297D0 (en) | 1986-12-03 |
| DE3782396T2 (de) | 1993-07-08 |
| US4908380A (en) | 1990-03-13 |
| DK576887A (da) | 1988-05-05 |
| GR3006099T3 (da) | 1993-06-21 |
| CA1308660C (en) | 1992-10-13 |
| DE3782396D1 (de) | 1992-12-03 |
| EP0266980B1 (en) | 1992-10-28 |
| AU608546B2 (en) | 1991-04-11 |
| JPS63130532A (ja) | 1988-06-02 |
| ES2052581T3 (es) | 1994-07-16 |
| EP0266980A3 (en) | 1989-11-08 |
| ZA877886B (en) | 1988-05-04 |
| DK576887D0 (da) | 1987-11-03 |
| AU8069887A (en) | 1988-05-05 |
| ATE81774T1 (de) | 1992-11-15 |
| EP0266980A2 (en) | 1988-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9K | Patent not in force due to non-payment of renewal fees |