IL73267A - Anhydrous,stable,crystalline delta-form of prazosin hydrochloride and a process for its preparation - Google Patents

Anhydrous,stable,crystalline delta-form of prazosin hydrochloride and a process for its preparation

Info

Publication number: IL73267A
Authority: IL; Israel
Prior art keywords: anhydrous; stable; preparation; prazosin hydrochloride; crystalline delta
Prior art date: 1984-06-25

Application number

IL73267A

Other languages

English (en)

Other versions

IL73267A0 (en

Original Assignee

Orion Yhtymae Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-25

Filing date

1984-10-19

Publication date

1988-06-30

1984-10-19 Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy

1985-01-31 Publication of IL73267A0 publication Critical patent/IL73267A0/xx

1988-06-30 Publication of IL73267A publication Critical patent/IL73267A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

IL73267A 1984-06-25 1984-10-19 Anhydrous,stable,crystalline delta-form of prazosin hydrochloride and a process for its preparation IL73267A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FI842544A FI79107C (fi)	1984-06-25	1984-06-25	Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.

Publications (2)

Publication Number	Publication Date
IL73267A0 IL73267A0 (en)	1985-01-31
IL73267A true IL73267A (en)	1988-06-30

Family

ID=8519293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL73267A IL73267A (en)	1984-06-25	1984-10-19	Anhydrous,stable,crystalline delta-form of prazosin hydrochloride and a process for its preparation

Country Status (17)

Country	Link
US (2)	US4739055A (de)
JP (1)	JPS6115881A (de)
AT (1)	AT389117B (de)
AU (1)	AU566814B2 (de)
BE (1)	BE900925A (de)
CH (1)	CH661045A5 (de)
DE (1)	DE3429415A1 (de)
FI (1)	FI79107C (de)
FR (1)	FR2567124B1 (de)
GB (1)	GB2160861B (de)
IL (1)	IL73267A (de)
IT (1)	IT1224142B (de)
LU (1)	LU85616A1 (de)
NL (1)	NL8403250A (de)
NZ (1)	NZ209962A (de)
PT (1)	PT79411B (de)
ZA (1)	ZA85910B (de)

Families Citing this family (31)

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EP0237608B1 (de) *	1986-03-21	1992-01-29	HEUMANN PHARMA GMBH & CO	Kristalline, wasserfreie Sigma -Form von 2-[4-(2-Furoyl-(2-piperazin)-1-yl]-4-amino-6,7-dimethoxychinazolinhydrochlorid und Verfahren zu ihrer Herstellung
JP2756846B2 (ja) *	1989-12-28	1998-05-25	住化ファインケム株式会社	無水のε型結晶体２―〔４―（２―フロイル）ピペラジン―１―イル〕―４―アミノ―６，７―ジメトキシキナゾリン塩酸塩及びその製造方法
JPH07206857A (ja) *	1993-12-28	1995-08-08	Synthelabo Sa	アルフゾシン塩酸塩の二水和物
IL157471A0 (en) *	2001-02-24	2004-03-28	Boehringer Ingelheim Pharma	Xanthine derivatives, production and use thereof as a medicament
US7407955B2 (en)	2002-08-21	2008-08-05	Boehringer Ingelheim Pharma Gmbh & Co., Kg	8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) *	2004-02-18	2009-03-10	Boehringer Ingelheim International Gmbh	8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de)	2004-11-05	2006-05-11	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) *	2005-07-30	2007-02-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (de)	2006-05-04	2007-11-07	Boehringer Ingelheim Pharma GmbH & Co.KG	Zusammensetzungen von DPP-IV-Inhibitoren
CA2873524C (en)	2006-05-04	2018-02-20	Boehringer Ingelheim International Gmbh	A polymeric form of 1-((4-methyl-quinazolin-2-yl)methyl)-3-7-(2-butyn-1-yl)-8-(3-(r)-aminopiperidin-1-yl)xanthine
PE20110235A1 (es)	2006-05-04	2011-04-14	Boehringer Ingelheim Int	Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
KR101610005B1 (ko) *	2007-08-17	2016-04-08	베링거 인겔하임 인터내셔날 게엠베하	Ｆａｂ 관련 질환의 치료에 사용하기 위한 푸린 유도체
AR071175A1 (es) *	2008-04-03	2010-06-02	Boehringer Ingelheim Int	Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
PE20100156A1 (es) *	2008-06-03	2010-02-23	Boehringer Ingelheim Int	Tratamiento de nafld
KR20190016601A (ko)	2008-08-06	2019-02-18	베링거 인겔하임 인터내셔날 게엠베하	메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es)	2008-08-06	2010-03-26	Boehringer Ingelheim Int	"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR101791403B1 (ko) *	2008-08-15	2017-10-30	베링거 인겔하임 인터내셔날 게엠베하	Ｆａｂ-관련 질환의 치료에 사용하기 위한 퓨린 유도체
WO2010029089A2 (en)	2008-09-10	2010-03-18	Boehringer Ingelheim International Gmbh	Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en)	2018-11-20	2020-05-21	Boehringer Ingelheim International Gmbh	Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CN107011345A (zh)	2008-12-23	2017-08-04	勃林格殷格翰国际有限公司	有机化合物的盐形式
AR074990A1 (es)	2009-01-07	2011-03-02	Boehringer Ingelheim Int	Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
JP2013512229A (ja)	2009-11-27	2013-04-11	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	遺伝子型が同定された糖尿病患者のリナグリプチン等のｄｄｐ−ｉｖ阻害薬による治療
ES2935300T3 (es)	2010-05-05	2023-03-03	Boehringer Ingelheim Int	Combiterapia
CA2803504C (en)	2010-06-24	2022-08-30	Boehringer Ingelheim International Gmbh	A combination for diabetes therapy comprising linagliptin and a long-acting insulin
AR083878A1 (es)	2010-11-15	2013-03-27	Boehringer Ingelheim Int	Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
JP5876150B2 (ja)	2011-07-15	2016-03-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	置換キナゾリン、これらの調製及び医薬組成物中のこれらの使用
US9555001B2 (en)	2012-03-07	2017-01-31	Boehringer Ingelheim International Gmbh	Pharmaceutical composition and uses thereof
EP3685839A1 (de)	2012-05-14	2020-07-29	Boehringer Ingelheim International GmbH	Linagliptin zur verwendung in der behandlung von albuminuria und nierenbedingten erkrankungen
WO2013174767A1 (en)	2012-05-24	2013-11-28	Boehringer Ingelheim International Gmbh	A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ES2950384T3 (es)	2014-02-28	2023-10-09	Boehringer Ingelheim Int	Uso médico de un inhibidor de DPP-4
WO2017211979A1 (en)	2016-06-10	2017-12-14	Boehringer Ingelheim International Gmbh	Combinations of linagliptin and metformin

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2969375A (en) *		1961-01-24		Certification of correction
DE156532C (de) *
BE427505A (de) *	1937-05-25
GB1156973A (en) *	1965-07-06	1969-07-02		Quinazoline Derivatives
US3433788A (en) *	1966-04-27	1969-03-18	Union Carbide Corp	Process for recovery of amines from aqueous solutions by solvent treatment and distillation
US3421983A (en) *	1967-03-07	1969-01-14	Lummus Co	Azeotropic distillation of aqueous toluene diamine
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3743672A (en) *	1970-05-27	1973-07-03	Halcon International Inc	Separation of water in alkylene glycol mono and diester purification by azeotropic distillation
GB1308718A (en) *	1970-07-01	1973-03-07	Sir Soc Italiana Resine Spa	Method of separating vinyl acetate from liquid mixtures
IT956765B (it) *	1972-06-22	1973-10-10	Montedison Spa	Procedimento per la purificazione di 1 3 diossolano
US3935213A (en) *	1973-12-05	1976-01-27	Pfizer Inc.	Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
US4026894A (en) *	1975-10-14	1977-05-31	Abbott Laboratories	Antihypertensive agents
US4001237A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	Oxazole, isoxazole, thiazole and isothiazole amides
US4092315A (en) *	1976-03-01	1978-05-30	Pfizer Inc.	Novel crystalline forms of prazosin hydrochloride
FI67699C (fi) *	1979-01-31	1985-05-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
FI64367C (fi) *	1980-02-26	1986-08-05	Orion Yhtymae Oy	Foerfarande foer framstaellning av alfa-form av prazosinhydroklorid

1984
- 1984-06-25 FI FI842544A patent/FI79107C/fi not_active IP Right Cessation
- 1984-08-09 DE DE19843429415 patent/DE3429415A1/de active Granted
- 1984-10-03 GB GB08424999A patent/GB2160861B/en not_active Expired
- 1984-10-15 US US06/660,871 patent/US4739055A/en not_active Expired - Lifetime
- 1984-10-19 AU AU34510/84A patent/AU566814B2/en not_active Ceased
- 1984-10-19 IL IL73267A patent/IL73267A/xx not_active IP Right Cessation
- 1984-10-23 NZ NZ209962A patent/NZ209962A/en unknown
- 1984-10-24 IT IT23292/84A patent/IT1224142B/it active
- 1984-10-25 NL NL8403250A patent/NL8403250A/nl not_active Application Discontinuation
- 1984-10-26 CH CH5142/84A patent/CH661045A5/de not_active IP Right Cessation
- 1984-10-26 PT PT79411A patent/PT79411B/pt not_active IP Right Cessation
- 1984-10-26 FR FR8416401A patent/FR2567124B1/fr not_active Expired - Lifetime
- 1984-10-29 JP JP59227640A patent/JPS6115881A/ja active Granted
- 1984-10-29 BE BE0/213911A patent/BE900925A/fr not_active IP Right Cessation
- 1984-10-29 LU LU85616A patent/LU85616A1/fr unknown
- 1984-10-30 AT AT0344184A patent/AT389117B/de not_active IP Right Cessation
1985
- 1985-02-06 ZA ZA85910A patent/ZA85910B/xx unknown
1988
- 1988-02-08 US US07/153,780 patent/US4873330A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI842544A0 (fi)	1984-06-25
US4873330A (en)	1989-10-10
JPS6115881A (ja)	1986-01-23
FI79107C (fi)	1989-11-10
DE3429415C2 (de)	1990-05-03
ZA85910B (en)	1985-09-25
DE3429415A1 (de)	1986-01-02
JPH0481993B2 (de)	1992-12-25
GB2160861B (en)	1987-11-18
PT79411B (en)	1986-09-15
FI79107B (fi)	1989-07-31
BE900925A (fr)	1985-02-15
IL73267A0 (en)	1985-01-31
ATA344184A (de)	1989-03-15
CH661045A5 (de)	1987-06-30
AT389117B (de)	1989-10-25
GB2160861A (en)	1986-01-02
IT1224142B (it)	1990-09-26
LU85616A1 (fr)	1985-06-04
IT8423292A0 (it)	1984-10-24
FR2567124B1 (fr)	1990-09-21
GB8424999D0 (en)	1984-11-07
FR2567124A1 (fr)	1986-01-10
AU3451084A (en)	1986-01-02
NL8403250A (nl)	1986-01-16
FI842544A (fi)	1985-12-26
US4739055A (en)	1988-04-19
PT79411A (en)	1984-11-01
AU566814B2 (en)	1987-10-29
NZ209962A (en)	1987-06-30

Publication	Publication Date	Title
IL73267A (en)	1988-06-30	Anhydrous,stable,crystalline delta-form of prazosin hydrochloride and a process for its preparation
US4816455B1 (en)	1992-11-24	Crystalline,anhydrous sigma-form of 2-(4-(2-furoyl)-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxy-quinoazoline hydrochloride and a process for its preparation
HUT38361A (en)	1986-05-28	Process for preparing new crystalline modifications
HUT44257A (en)	1988-02-29	Process for preparing crystalline cefalosporinhydrate
PT80412A (en)	1985-06-01	Process for preparing an anhydrous dentifrice
ZA859390B (en)	1986-08-27	Method for production of stable nicorandil preparation
PT81566A (en)	1985-12-01	Process for preparing amino-salicylic acid derivatives
PT80270A (en)	1985-05-01	Process for preparing 9a-aza-9a-homoerytromycin of derivatives
ZA862929B (en)	1986-12-30	Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride
HUT36805A (en)	1985-10-28	Process for preparing 1-cyclopropyl-quinoline- and -naphthyridine-carboxylic acid derivatives
HUT40115A (en)	1986-11-28	Process for preparing sylbinine free of isosylbine
YU156985A (en)	1987-10-31	Process for producing ammonia
YU228688A (en)	1990-08-31	Process for preparing new ammonia compounds
DE3476748D1 (en)	1989-03-23	Crystalline silica, its salts and method of preparing same
PH21354A (en)	1987-10-15	1-phenylimidazole-5-carboxylic acid derivatives, a process for their preparation and their use as growth regulators
YU43689B (en)	1989-10-31	Process for preparing derivatives of silibinine
HUT43992A (en)	1988-01-28	Process for production of crystalline metall-gluconates
DE3665875D1 (en)	1989-11-02	Crystalline polyester-imides, process for production thereof, and use thereof
EG17668A (en)	1990-08-30	Process for preparing of a bromodichlorimidazole insecticide
HUT36800A (en)	1985-10-28	Process for preparing carbamidic acid derivatives
CS987985A1 (en)	1988-10-14	Crystalline form of a 1-benzydril-4-aryl--piperazindyhydrochloride and process for preparing thereof
PL253585A1 (en)	1986-02-25	Process for preparing derivatives of d-/-/-alpha-aminopenicillins
YU219586A (en)	1988-10-31	Process for preparing crystalline cimetidine
PL246702A2 (en)	1985-01-30	Process for preparing novel derivatives of n-benzylaniline
PL138011B2 (en)	1986-08-30	Process for preparing 2,5-dinitrate of 1,4:3,6-dianhydro-d-sorbite

Legal Events

Date	Code	Title	Description
1999-10-28	RH	Patent void