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IL71017A - Hybrid cell lines,monoclonal antibodies prepared thereby and their use in the purification,diagnosis and detection of human interferon of type alpha - Google Patents

Hybrid cell lines,monoclonal antibodies prepared thereby and their use in the purification,diagnosis and detection of human interferon of type alpha

Info

Publication number
IL71017A
IL71017A IL71017A IL7101784A IL71017A IL 71017 A IL71017 A IL 71017A IL 71017 A IL71017 A IL 71017A IL 7101784 A IL7101784 A IL 7101784A IL 71017 A IL71017 A IL 71017A
Authority
IL
Israel
Prior art keywords
diagnosis
purification
detection
cell lines
monoclonal antibodies
Prior art date
Application number
IL71017A
Other versions
IL71017A0 (en
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IL71017A0 publication Critical patent/IL71017A0/en
Publication of IL71017A publication Critical patent/IL71017A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL71017A 1983-02-22 1984-02-21 Hybrid cell lines,monoclonal antibodies prepared thereby and their use in the purification,diagnosis and detection of human interferon of type alpha IL71017A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833306060 DE3306060A1 (en) 1983-02-22 1983-02-22 NEW IMMUNGLOBULIN-PRODUCING HYBRID CELL LINES, THEIR USE AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
IL71017A0 IL71017A0 (en) 1984-05-31
IL71017A true IL71017A (en) 1987-12-31

Family

ID=6191474

Family Applications (1)

Application Number Title Priority Date Filing Date
IL71017A IL71017A (en) 1983-02-22 1984-02-21 Hybrid cell lines,monoclonal antibodies prepared thereby and their use in the purification,diagnosis and detection of human interferon of type alpha

Country Status (7)

Country Link
EP (1) EP0119476A3 (en)
JP (1) JPS59224687A (en)
DE (1) DE3306060A1 (en)
DK (1) DK85084A (en)
ES (2) ES8503371A1 (en)
FI (1) FI840675A (en)
IL (1) IL71017A (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
DE3515336C2 (en) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Process for the preparation and purification of â-interferon
AU6032786A (en) * 1985-07-25 1987-01-29 University Of Minnesota Detection, imaging and therapy of renal cell carcinoma with monoclonal antibodies in vivo
GB8615353D0 (en) * 1986-06-24 1986-07-30 Antibioticos Sa Interferon
DE3633323A1 (en) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int NEW MONOCLONAL ANTIBODIES AGAINST IFN-OMEGA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CLEANING AND DETECTING IFN-OMEGA
SE468251B (en) 1989-06-20 1992-11-30 Bionative Ab CLEANING PROCESS FOR INTERFERON
EP0538300B1 (en) * 1990-07-10 1994-04-13 BOEHRINGER INGELHEIM INTERNATIONAL GmbH O-glycosylated ifn-alpha
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
BRPI0720035A2 (en) 2006-12-06 2019-05-07 Medimmune, Llc methods for treating a patient having a disease or disorder, for treating a patient with autoimmune disease, for neutralizing an ifn inducible type 1 or ifnalfa pd marker expression profile in a patient, for monitoring or predicting autoimmune disease progression of a patient to monitor disease progression of a patient receiving treatment with a therapeutic agent that binds to and modulates ifnalfa activity, to identify a patient as a candidate for a therapeutic agent that binds to and modulates the activity of ifnalfa ifnalfa, to diagnose a patient as having a disorder associated with increased ifnalfa levels, to identify a therapeutic candidate for the treatment of ifnalfa-mediated disorders, and to detect ifn activity in a sample, probe set, and kit
JP2010526107A (en) 2007-05-03 2010-07-29 メディミューン，エルエルシー Autoantibody markers for autoimmune diseases
SI2219452T1 (en) 2007-11-05 2016-03-31 Medimmune, Llc Methods of treating scleroderma
ES2529593T3 (en) 2008-02-08 2015-02-23 Medimmune, Llc Disease markers and their uses
MX2012002640A (en) 2009-09-03 2012-06-25 Medimmune Llc Type 1 interferon diagnostic.
CA3128785A1 (en) 2019-02-15 2020-08-20 Astrazeneca Ab Type i interferon-mediated disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (en) * 1979-04-20 1989-05-10 Technobiotic Ltd Process for the preparation and purification of human Le-shaped interferon protein.
GB2083836B (en) * 1980-04-11 1984-03-28 Burke Derek Clissold Monoclonal antibody
FR2500754B1 (en) * 1981-02-27 1986-06-27 Hoffmann La Roche MONOCLONAL ANTIBODIES
WO1984003106A1 (en) * 1983-02-04 1984-08-16 Wadley Inst Of Molecular Medic Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins
GB8303165D0 (en) * 1983-02-04 1983-03-09 Secher D S Monoclonal antibody

Also Published As

Publication number Publication date
DK85084D0 (en) 1984-02-21
ES8505409A1 (en) 1985-05-16
EP0119476A3 (en) 1987-04-08
ES529912A0 (en) 1985-02-16
IL71017A0 (en) 1984-05-31
FI840675A (en) 1984-08-23
ES8503371A1 (en) 1985-02-16
EP0119476A2 (en) 1984-09-26
ES535509A0 (en) 1985-05-16
DK85084A (en) 1984-08-23
FI840675A0 (en) 1984-02-20
DE3306060A1 (en) 1984-08-23
JPS59224687A (en) 1984-12-17

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Legal Events

Date Code Title Description
MM9K Patent not in force due to non-payment of renewal fees