IL64875A0 - Quinazoline derivatives - Google Patents

Quinazoline derivatives

Info

Publication number: IL64875A0
Authority: IL; Israel
Prior art keywords: quinazoline derivatives; quinazoline; derivatives
Prior art date: 1981-03-06

Application number

IL64875A

Other languages

English (en)

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-03-06

Filing date

1982-01-26

Publication date

1982-03-31

1982-01-26 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1982-03-31 Publication of IL64875A0 publication Critical patent/IL64875A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL64875A 1981-03-06 1982-01-26 Quinazoline derivatives IL64875A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/241,317 US4343940A (en)	1979-02-13	1981-03-06	Anti-tumor quinazoline compounds

Publications (1)

Publication Number	Publication Date
IL64875A0 true IL64875A0 (en)	1982-03-31

Family

ID=22910195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL64875A IL64875A0 (en)	1981-03-06	1982-01-26	Quinazoline derivatives

Country Status (31)

Country	Link
US (1)	US4343940A (xx)
JP (1)	JPS57158780A (xx)
KR (1)	KR880001852B1 (xx)
AR (1)	AR231138A1 (xx)
AT (1)	AT380476B (xx)
AU (1)	AU556099B2 (xx)
BE (1)	BE891936A (xx)
CA (1)	CA1163995A (xx)
CH (1)	CH647776A5 (xx)
CY (1)	CY1371A (xx)
DE (1)	DE3203770C2 (xx)
DK (1)	DK159442C (xx)
ES (1)	ES509434A0 (xx)
FI (1)	FI71559C (xx)
FR (1)	FR2501207B1 (xx)
GB (1)	GB2094295B (xx)
GR (1)	GR75903B (xx)
HK (1)	HK4588A (xx)
HU (1)	HU189997B (xx)
IE (1)	IE52385B1 (xx)
IL (1)	IL64875A0 (xx)
IT (1)	IT1154272B (xx)
KE (1)	KE3715A (xx)
LU (1)	LU83903A1 (xx)
NL (1)	NL8200473A (xx)
NZ (1)	NZ199576A (xx)
PH (1)	PH18529A (xx)
PT (1)	PT74394B (xx)
SE (1)	SE461732B (xx)
SG (1)	SG30787G (xx)
YU (1)	YU42031B (xx)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
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DE3131365A1 (de) *	1981-08-07	1983-02-24	Henkel KGaA, 4000 Düsseldorf	Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4963554A (en) *	1990-02-14	1990-10-16	Ortho Pharmaceutical Corporation	6,7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US5030635A (en) *	1990-02-14	1991-07-09	Ortho Pharmaceutical Corporation	6-7-dimethoxy-1,2-dihydro-2-arylquinazoline-3-oxides
US5710158A (en) *	1991-05-10	1998-01-20	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
US6645969B1 (en) *	1991-05-10	2003-11-11	Aventis Pharmaceuticals Inc.	Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
US5480883A (en) *	1991-05-10	1996-01-02	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
US5714493A (en) *	1991-05-10	1998-02-03	Rhone-Poulenc Rorer Pharmaceuticals, Inc.	Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
USRE37650E1 (en)	1991-05-10	2002-04-09	Aventis Pharmacetical Products, Inc.	Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
PT100905A (pt) *	1991-09-30	1994-02-28	Eisai Co Ltd	Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
ATE188377T1 (de) *	1993-06-29	2000-01-15	Takeda Chemical Industries Ltd	Chinoline oder chinazolin-derivate und deren verwendung zur herstellung eines medikaments für die behandlung von osteoporose
US5804396A (en) *	1994-10-12	1998-09-08	Sugen, Inc.	Assay for agents active in proliferative disorders
TW321649B (xx) *	1994-11-12	1997-12-01	Zeneca Ltd
GB9424233D0 (en) *	1994-11-30	1995-01-18	Zeneca Ltd	Quinazoline derivatives
US5837524A (en) *	1994-12-15	1998-11-17	Sugen, Inc.	PYK2 related polynucleotide products
US5837815A (en) *	1994-12-15	1998-11-17	Sugen, Inc.	PYK2 related polypeptide products
GB9508535D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivative
DE69613367T2 (de) *	1995-04-27	2002-04-18	Astrazeneca Ab, Soedertaelje	Chinazolin derivate
GB9508565D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quiazoline derivative
GB9508538D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
GB9508537D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
DE69618587T2 (de) *	1995-06-07	2002-08-29	Sugen, Inc.	Chinazoline und pharmazeutische zusammensetzungen
WO1997017329A1 (fr) *	1995-11-07	1997-05-15	Kirin Beer Kabushiki Kaisha	Derives de quinoline et derives de quinazoline inhibant l'autophosphorylation d'un recepteur de facteur de croissance originaire de plaquettes, et compositions pharmaceutiques les contenant
US7119174B2 (en) *	1995-12-18	2006-10-10	Sugen, Inc.	Diagnosis and treatment of AUR1 and/or AUR2 related disorders
GB9624482D0 (en)	1995-12-18	1997-01-15	Zeneca Phaema S A	Chemical compounds
US6716575B2 (en)	1995-12-18	2004-04-06	Sugen, Inc.	Diagnosis and treatment of AUR1 and/or AUR2 related disorders
HUP9901155A3 (en)	1996-02-13	2003-04-28	Astrazeneca Ab	Quinazoline derivatives as vegf inhibitors
GB9603095D0 (en) *	1996-02-14	1996-04-10	Zeneca Ltd	Quinazoline derivatives
GB9603097D0 (en) *	1996-02-14	1996-04-10	Zeneca Ltd	Quinazoline compounds
AU719327B2 (en)	1996-03-05	2000-05-04	Astrazeneca Ab	4-anilinoquinazoline derivatives
GB9607729D0 (en) *	1996-04-13	1996-06-19	Zeneca Ltd	Quinazoline derivatives
GB9718972D0 (en) *	1996-09-25	1997-11-12	Zeneca Ltd	Chemical compounds
CA2274805A1 (en) *	1996-12-11	1998-06-18	Sugen, Inc.	Pyk2 related products and methods
US6818440B2 (en) *	1997-04-28	2004-11-16	Sugen, Inc.	Diagnosis and treatment of alk-7 related disorders
US6228641B1 (en)	1997-05-20	2001-05-08	Sugen, Inc.	Diagnosis and treatment of PTP04 related disorders
US6342593B1 (en)	1997-06-11	2002-01-29	Sugen, Inc.	Diagnosis and treatment of ALP related disorders
US7115710B2 (en) *	1997-06-11	2006-10-03	Sugen, Inc.	Diagnosis and treatment of PTP related disorders
US6388063B1 (en) *	1997-06-18	2002-05-14	Sugen, Inc.	Diagnosis and treatment of SAD related disorders
AU2237899A (en) *	1998-01-21	1999-08-09	Sugen, Inc.	Human orthologues of wart
WO1999053036A2 (en)	1998-04-14	1999-10-21	Sugen, Inc.	Ste20-related protein kinases
CA2333392A1 (en)	1998-05-28	1999-12-02	Parker Hughes Institute	Quinazolines for treating brain tumor
US6800649B1 (en)	1998-06-30	2004-10-05	Parker Hughes Institute	Method for inhibiting c-jun expression using JAK-3 inhibitors
MXPA01001893A (es) *	1998-08-21	2002-04-24	Parker Hughes Inst	Derivados de quinazolina.
US6861442B1 (en) *	1998-12-30	2005-03-01	Sugen, Inc.	PYK2 and inflammation
US6080747A (en) *	1999-03-05	2000-06-27	Hughes Institute	JAK-3 inhibitors for treating allergic disorders
US6258820B1 (en)	1999-03-19	2001-07-10	Parker Hughes Institute	Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
US20030162223A1 (en) *	1999-10-22	2003-08-28	Lowery David E.	Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
EP1222273A2 (en) *	1999-10-22	2002-07-17	PHARMACIA & UPJOHN COMPANY	Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
US7364866B2 (en) *	1999-10-22	2008-04-29	Pharmacia & Upjohn Company	Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
DK1676845T3 (da)	1999-11-05	2008-09-15	Astrazeneca Ab	Nye quinazolinderivater
AU784543B2 (en) *	1999-11-16	2006-04-27	Pharmacia & Upjohn Company	Novel G protein-coupled receptors
US20030082534A1 (en) *	1999-11-16	2003-05-01	Peter Lind	Novel G protein-coupled receptors
US20030003451A1 (en) *	2000-02-23	2003-01-02	Gabriel Vogeli	Novel G protein-coupled receptors
CN1240688C (zh) *	2000-04-07	2006-02-08	阿斯特拉曾尼卡有限公司	喹唑啉化合物
US20050069976A1 (en) *	2001-02-14	2005-03-31	Peter Lind	Protein-coupled receptor
US8450302B2 (en) *	2002-08-02	2013-05-28	Ab Science	2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors
CN100491374C (zh) *	2002-08-02	2009-05-27	Ab科学公司	2-(3-氨基芳基)氨基-4-芳基-噻唑及其作为c-kit抑制剂的应用
ATE465731T1 (de) *	2003-10-23	2010-05-15	Ab Science	2-aminoaryloxazol-verbindungen als tyrosinkinase- hemmer
CN101217954B (zh)	2005-04-04	2013-07-10	Ab科学公司	经取代的噁唑衍生物及其作为酪氨酸激酶抑制剂的用途
US8246966B2 (en) *	2006-08-07	2012-08-21	University Of Georgia Research Foundation, Inc.	Trypanosome microsome system and uses thereof
CA2663436A1 (en)	2006-10-04	2008-04-10	Pfizer Products Inc.	Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists
US8338433B2 (en) *	2006-11-22	2012-12-25	University Of Georgia Research Foundation, Inc.	Tyrosine kinase inhibitors as anti-kinetoplastid agents
JP2010511382A (ja) *	2006-12-01	2010-04-15	エージェンシーフォーサイエンス，テクノロジーアンドリサーチ	癌関連タンパク質キナーゼ
CA2828713C (en)	2011-03-04	2022-08-16	Newgen Therapeutics, Inc.	Alkyne substituted quinazoline compounds and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3298291A (en) *	1965-12-28	1967-01-17	Jack D Layton	Paver screed assembly
US3455920A (en) *	1967-01-13	1969-07-15	Squibb & Sons Inc	2,3-dihydro-5 and 6-substituted-2-phenyl-4(1h)-quinazolinones
US3637693A (en) *	1968-07-12	1972-01-25	Du Pont	Hydroxyarylquinazolines and their use as uv-absorbers
DE2050092C3 (de)	1970-10-13	1980-04-24	Bayer Ag, 5090 Leverkusen	Chinazolondiurethane, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten
DE2162327C3 (de) *	1970-12-23	1975-09-18	Sumitomo Chemical Co., Ltd., Osaka (Japan)	Verfahren zur Herstellung von 3,4-Oihydro-2(1 H)-chinazolinonen
JPS6011032B2 (ja)	1975-12-16	1985-03-22	大鵬薬品工業株式会社	２―置換―５―フルオルピリミジン―４―オン誘導体の製造法
US4080455A (en) *	1975-12-16	1978-03-21	Taisho Pharmaceutical Company Limited	5-Fluoropyrimidin-4-one compositions

1981
- 1981-03-06 US US06/241,317 patent/US4343940A/en not_active Expired - Lifetime
1982
- 1982-01-25 PH PH26788A patent/PH18529A/en unknown
- 1982-01-26 IE IE163/82A patent/IE52385B1/en not_active IP Right Cessation
- 1982-01-26 IL IL64875A patent/IL64875A0/xx not_active IP Right Cessation
- 1982-01-27 NZ NZ199576A patent/NZ199576A/en unknown
- 1982-01-28 GR GR67142A patent/GR75903B/el unknown
- 1982-01-28 LU LU83903A patent/LU83903A1/fr unknown
- 1982-01-28 BE BE0/207169A patent/BE891936A/fr not_active IP Right Cessation
- 1982-01-29 AU AU79981/82A patent/AU556099B2/en not_active Ceased
- 1982-01-29 SE SE8200526A patent/SE461732B/sv not_active IP Right Cessation
- 1982-02-02 GB GB8202948A patent/GB2094295B/en not_active Expired
- 1982-02-02 CY CY137182A patent/CY1371A/xx unknown
- 1982-02-03 AT AT0039582A patent/AT380476B/de not_active IP Right Cessation
- 1982-02-03 IT IT47713/82A patent/IT1154272B/it active
- 1982-02-04 CA CA000395526A patent/CA1163995A/en not_active Expired
- 1982-02-04 DE DE3203770A patent/DE3203770C2/de not_active Expired - Fee Related
- 1982-02-05 DK DK050482A patent/DK159442C/da not_active IP Right Cessation
- 1982-02-05 YU YU256/82A patent/YU42031B/xx unknown
- 1982-02-05 PT PT74394A patent/PT74394B/pt not_active IP Right Cessation
- 1982-02-08 ES ES509434A patent/ES509434A0/es active Granted
- 1982-02-08 FI FI820399A patent/FI71559C/fi not_active IP Right Cessation
- 1982-02-08 HU HU82376A patent/HU189997B/hu not_active IP Right Cessation
- 1982-02-08 CH CH764/82A patent/CH647776A5/de not_active IP Right Cessation
- 1982-02-08 FR FR8201979A patent/FR2501207B1/fr not_active Expired
- 1982-02-08 NL NL8200473A patent/NL8200473A/nl not_active Application Discontinuation
- 1982-02-08 AR AR288365A patent/AR231138A1/es active Active
- 1982-02-09 JP JP57018307A patent/JPS57158780A/ja active Granted
- 1982-02-09 KR KR8200576A patent/KR880001852B1/ko active
1987
- 1987-03-27 SG SG307/87A patent/SG30787G/en unknown
- 1987-03-31 KE KE3715A patent/KE3715A/xx unknown
1988
- 1988-01-21 HK HK45/88A patent/HK4588A/xx unknown

Also Published As

Publication number	Publication date
IT8247713A0 (it)	1982-02-03
DE3203770A1 (de)	1982-11-11
NZ199576A (en)	1986-05-09
GR75903B (xx)	1984-08-02
CA1163995A (en)	1984-03-20
ES8304095A1 (es)	1983-02-16
IE820163L (en)	1982-09-06
CY1371A (en)	1987-08-07
GB2094295A (en)	1982-09-15
KR830009050A (ko)	1983-12-17
HK4588A (en)	1988-01-29
FI71559C (fi)	1987-01-19
AU7998182A (en)	1982-09-09
CH647776A5 (de)	1985-02-15
BE891936A (fr)	1982-07-28
PH18529A (en)	1985-08-02
AU556099B2 (en)	1986-10-23
FR2501207A1 (fr)	1982-09-10
DK159442C (da)	1991-03-18
FI71559B (fi)	1986-10-10
KR880001852B1 (ko)	1988-09-22
PT74394B (en)	1984-10-22
YU25682A (en)	1985-03-20
ATA39582A (de)	1985-10-15
JPS57158780A (en)	1982-09-30
NL8200473A (nl)	1982-10-01
AT380476B (de)	1986-05-26
FR2501207B1 (fr)	1985-12-06
KE3715A (en)	1987-04-16
SE8200526L (sv)	1982-09-07
DK50482A (da)	1982-09-07
AR231138A1 (es)	1984-09-28
PT74394A (en)	1982-03-01
YU42031B (en)	1988-04-30
SG30787G (en)	1988-09-16
US4343940A (en)	1982-08-10
HU189997B (en)	1986-08-28
IE52385B1 (en)	1987-10-14
DK159442B (da)	1990-10-15
FI820399L (fi)	1982-09-07
LU83903A1 (fr)	1982-09-13
IT1154272B (it)	1987-01-21
JPH0337552B2 (xx)	1991-06-05
GB2094295B (en)	1984-09-12
ES509434A0 (es)	1983-02-16
DE3203770C2 (de)	1993-11-04
SE461732B (sv)	1990-03-19

Publication	Publication Date	Title
IL64875A0 (en)	1982-03-31	Quinazoline derivatives
ZA821308B (en)	1983-10-26	N-naphthoylglycine derivatives
GB8417905D0 (en)	1984-08-15	Hydroxymethyl-5 oxazolidinic derivatives
GB2068961B (en)	1983-11-30	Quinazoline derivatives
IL65799A0 (en)	1982-08-31	2-amino-1-alkanol derivatives
GB2111483B (en)	1986-04-16	3-acylamino-4-hydroxy-phenethylamine derivatives
GB2101986B (en)	1985-09-18	Thiazolinoazetidinone derivatives
IL64774A0 (en)	1982-03-31	Hexahydro-trans-and tetrahydropyridoindole derivatives
GB2099424B (en)	1985-10-30	Isoprenylamine derivatives
GB2099419B (en)	1985-01-09	Imidazothizole derivatives
GB2155932B (en)	1986-05-08	Phenylhydrazinomethylenemalononitrile derivatives
PH19011A (en)	1985-12-03	Quinazoline derivatives
GB2094297B (en)	1984-10-24	Apovincaminol derivatives
GB2098613B (en)	1985-01-09	Polyisoprenylamine derivatives
GB2099423B (en)	1985-06-05	Isopyrenylamine derivatives
PH17368A (en)	1984-08-06	Benzoyl-phenyl-piperidine derivatives
GB2112781B (en)	1985-12-18	Aminopropylaminobleomycin derivatives
EP0066144A3 (en)	1983-11-30	Benzylazole derivatives
GB2100728B (en)	1985-05-30	3-substituted -2- cyclopentenone derivatives
GB2106908B (en)	1985-05-30	Alkoxyvincamone derivatives
GB2108105B (en)	1985-06-12	Isoprenylamine derivatives
ZA832792B (en)	1983-12-28	Quinazoline derivatives
GB2098202B (en)	1984-12-12	Tetrachloropentene derivatives
GB2096609B (en)	1984-09-12	Thiazolotriazine derivatives
IE802105L (en)	1981-04-12	Quinazoline derivatives

Legal Events

Date	Code	Title	Description
1996-10-31	RH	Patent void