IL64724A0 - 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them - Google Patents

2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them

Info

Publication number: IL64724A0
Authority: IL; Israel
Prior art keywords: halobenzoyl; esters; salts; amino; pharmaceutical compositions
Prior art date: 1981-02-17

Application number

IL64724A

Original Assignee

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-02-17

Filing date

1982-01-07

Publication date

1982-03-31

1982-01-07 Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H

1982-03-31 Publication of IL64724A0 publication Critical patent/IL64724A0/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/32—Phenylacetic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)

IL64724A 1981-02-17 1982-01-07 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them IL64724A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US23453181A	1981-02-17	1981-02-17

Publications (1)

Publication Number	Publication Date
IL64724A0 true IL64724A0 (en)	1982-03-31

Family

ID=22881752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL64724A IL64724A0 (en)	1981-02-17	1982-01-07	2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them

Country Status (32)

Country	Link
JP (1)	JPS57149256A (en)
KR (1)	KR880002289B1 (en)
AT (1)	AT387213B (en)
AU (1)	AU7950382A (en)
BE (1)	BE892156A (en)
CA (1)	CA1173852A (en)
CH (1)	CH651294A5 (en)
DE (1)	DE3204854C2 (en)
DK (1)	DK155936C (en)
EG (1)	EG15798A (en)
ES (1)	ES509622A0 (en)
FI (1)	FI73970C (en)
FR (1)	FR2499981B1 (en)
GB (1)	GB2093027B (en)
GR (1)	GR76516B (en)
HK (1)	HK90384A (en)
HU (1)	HU187644B (en)
IE (1)	IE52289B1 (en)
IL (1)	IL64724A0 (en)
IT (1)	IT1157001B (en)
KE (1)	KE3454A (en)
LU (1)	LU83928A1 (en)
MY (1)	MY8500908A (en)
NL (1)	NL8200607A (en)
NO (1)	NO160133C (en)
NZ (1)	NZ199745A (en)
PL (1)	PL139815B1 (en)
PT (1)	PT74441B (en)
SE (1)	SE453387B (en)
SG (1)	SG68584G (en)
YU (1)	YU44333B (en)
ZA (1)	ZA82697B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4683242A (en) *	1985-10-28	1987-07-28	A. H. Robins Company, Incorporated	Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters
US5475034A (en) *	1994-06-06	1995-12-12	Alcon Laboratories, Inc.	Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
US6034266A (en) *	1996-03-11	2000-03-07	Fundacao Oswaldo Cruz-Fiocruz	Gem-difluoro derivative of phenylacetamide and phenylacetic acid and their pharmaceutical uses
BR9600975A (en) *	1996-03-11	1997-12-30	Fundacao Oswaldo Cruz	Derivatives of gem-difluorphenylacetic acid and gem-difluorphenylacetamide process of their preparation and their pharmaceutical applications
AR030345A1 (en) *	2000-08-14	2003-08-20	Alcon Inc	METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
AR030346A1 (en)	2000-08-14	2003-08-20	Alcon Inc	METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE
WO2002078681A2 (en)	2001-04-02	2002-10-10	Alcon, Inc.	Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
TWI358290B (en)	2004-12-02	2012-02-21	Alcon Inc	Topical nepafenac formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1226344A (en) *	1967-07-31	1971-03-24
US3997368A (en) *	1975-06-24	1976-12-14	Bell Telephone Laboratories, Incorporated	Elimination of stacking faults in silicon devices: a gettering process
CH577461A5 (en) *	1975-08-13	1976-07-15	Robins Co Inc A H
FR2366015A1 (en) *	1975-11-05	1978-04-28	Robins Co Inc A H	Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity
IL61945A (en) *	1980-02-19	1984-09-30	Robins Co Inc A H	2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

1982
- 1982-01-07 IL IL64724A patent/IL64724A0/en not_active IP Right Cessation
- 1982-01-14 AU AU79503/82A patent/AU7950382A/en not_active Abandoned
- 1982-01-24 EG EG8228A patent/EG15798A/en active
- 1982-02-01 JP JP57014710A patent/JPS57149256A/en active Granted
- 1982-02-03 ZA ZA82697A patent/ZA82697B/en unknown
- 1982-02-05 AT AT0043382A patent/AT387213B/en not_active IP Right Cessation
- 1982-02-08 FI FI820392A patent/FI73970C/en not_active IP Right Cessation
- 1982-02-09 CH CH791/82A patent/CH651294A5/en not_active IP Right Cessation
- 1982-02-09 LU LU83928A patent/LU83928A1/en unknown
- 1982-02-10 IT IT67152/82A patent/IT1157001B/en active
- 1982-02-11 DE DE3204854A patent/DE3204854C2/en not_active Expired - Fee Related
- 1982-02-12 GB GB8204137A patent/GB2093027B/en not_active Expired
- 1982-02-15 YU YU325/82A patent/YU44333B/en unknown
- 1982-02-15 SE SE8200891A patent/SE453387B/en unknown
- 1982-02-15 IE IE310/82A patent/IE52289B1/en not_active IP Right Cessation
- 1982-02-15 GR GR67320A patent/GR76516B/el unknown
- 1982-02-16 CA CA000396392A patent/CA1173852A/en not_active Expired
- 1982-02-16 PT PT74441A patent/PT74441B/en not_active IP Right Cessation
- 1982-02-16 KR KR8200673A patent/KR880002289B1/en active
- 1982-02-16 NL NL8200607A patent/NL8200607A/en not_active Application Discontinuation
- 1982-02-16 DK DK067382A patent/DK155936C/en not_active IP Right Cessation
- 1982-02-16 PL PL1982235095A patent/PL139815B1/en unknown
- 1982-02-16 HU HU82464A patent/HU187644B/en unknown
- 1982-02-16 BE BE0/207327A patent/BE892156A/en not_active IP Right Cessation
- 1982-02-16 NO NO820468A patent/NO160133C/en unknown
- 1982-02-16 ES ES509622A patent/ES509622A0/en active Granted
- 1982-02-16 NZ NZ199745A patent/NZ199745A/en unknown
- 1982-02-16 FR FR8202507A patent/FR2499981B1/en not_active Expired
1984
- 1984-09-17 KE KE3454A patent/KE3454A/en unknown
- 1984-09-21 SG SG68584A patent/SG68584G/en unknown
- 1984-11-15 HK HK903/84A patent/HK90384A/en unknown
1985
- 1985-12-30 MY MY908/85A patent/MY8500908A/en unknown

Also Published As

Publication number	Publication date
KR830008990A (en)	1983-12-16
BE892156A (en)	1982-06-16
KR880002289B1 (en)	1988-10-22
DE3204854A1 (en)	1982-09-09
ZA82697B (en)	1983-01-26
JPS57149256A (en)	1982-09-14
LU83928A1 (en)	1983-06-07
PL235095A1 (en)	1982-11-08
HU187644B (en)	1986-02-28
KE3454A (en)	1984-10-12
EG15798A (en)	1986-06-30
ES8301895A1 (en)	1982-12-16
DK155936C (en)	1989-11-06
NO160133C (en)	1989-03-15
PL139815B1 (en)	1987-02-28
SE8200891L (en)	1982-08-18
MY8500908A (en)	1985-12-31
GB2093027B (en)	1984-07-04
NZ199745A (en)	1985-07-12
FR2499981B1 (en)	1986-05-23
AU7950382A (en)	1982-08-26
DK67382A (en)	1982-08-18
FI73970B (en)	1987-08-31
FR2499981A1 (en)	1982-08-20
GB2093027A (en)	1982-08-25
IE820310L (en)	1982-08-17
NO820468L (en)	1982-08-18
IT1157001B (en)	1987-02-11
DK155936B (en)	1989-06-05
FI73970C (en)	1987-12-10
NO160133B (en)	1988-12-05
PT74441B (en)	1983-08-24
HK90384A (en)	1984-11-23
JPH0365338B2 (en)	1991-10-11
YU44333B (en)	1990-06-30
SG68584G (en)	1985-03-15
NL8200607A (en)	1982-09-16
SE453387B (en)	1988-02-01
FI820392L (en)	1982-08-18
ES509622A0 (en)	1982-12-16
IT8267152A0 (en)	1982-02-10
CA1173852A (en)	1984-09-04
CH651294A5 (en)	1985-09-13
PT74441A (en)	1982-03-01
YU32582A (en)	1985-06-30
IE52289B1 (en)	1987-09-02
AT387213B (en)	1988-12-27
ATA43382A (en)	1988-05-15
DE3204854C2 (en)	1994-06-16
GR76516B (en)	1984-08-10

Publication	Publication Date	Title
MY8600029A (en)	1986-12-31	2-hydroxy-5-phenylazobenzoic acid derivatives and pharmaceutical compositions containing themn
IL59628A (en)	1983-06-15	4-amino-3-quinolinecarboxylic acids and salts and esters thereof and pharmaceutical compositions containing them
GB2118042B (en)	1986-01-15	Pharmaceutical compositions containing biphosphonic acids
IL78528A0 (en)	1986-08-31	Difluoro-naphthyridine-and trifluoro-quinoline-carboxylic acids and esters and salts thereof and pharmaceutical compositions containing them
IL64185A0 (en)	1982-02-28	1-carboxy-azaalkanoylindoline-2-carboxylic acids and ester and amide derivatives thereof,their manufacture and pharmaceutical compositions containing them
JPS57144219A (en)	1982-09-06	Azobissalicylic acid and salts thereof and medicinal composition containing them
GB2126224B (en)	1986-05-21	Derivatives of w-amino acids the preparation and utilisation thereof and the compositions containing these derivatives
NZ216971A (en)	1989-05-29	Phosphonate esters and pharmaceutical compositions
IL64732A0 (en)	1982-03-31	Carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
ZA822933B (en)	1983-04-27	Aminocyclopentanol acids and esters and their preparation and pharmaceutical formulation
IL64724A0 (en)	1982-03-31	2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them
IL61945A0 (en)	1981-02-27	2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
IL72157A (en)	1988-04-29	6-alpha-hydroxyethyl-2-substituted-2-penem-3-carboxylic acid derivatives and pharmaceutical compositions comprising them
DE3265871D1 (en)	1985-10-03	3-amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same
GB2057427B (en)	1983-05-18	Oxoimidazolinealkanoic acids and their salts and esters their preparation and pharmaceutical compositions containing them
IL62449A0 (en)	1981-05-20	Peptides and salts thereof and pharmaceutical compositions containing them
DE2967551D1 (en)	1986-01-16	5(6)-(2-amino-5-thiazoloyl)benzimidazole-2-carbamic acid esters and their salts, their preparation and use, and pharmaceutical compositions containing them
IL62541A0 (en)	1981-06-29	Mono salts of heterocyclic dicarboxylic acids and pharmaceutical compositions containing them
GB2110930B (en)	1985-10-02	Pharmaceutical compositions containing propionhydroxamic acid
GB2113214B (en)	1985-03-27	New phenylacetic acid derivatives their preparation and compositions containing them
IL60444A0 (en)	1980-09-16	2-amino-3-(alkylthiobenzoyl)-phenylacetic acids and pharmaceutical compositions containing them
GB2110536B (en)	1986-10-29	Pharmaceutical compositions containing pantetheine-s-sulphonic acid
EP0308665A3 (en)	1989-08-16	5-aminosalicylic acid salts and pharmaceutical preparations containing them
GB2080300B (en)	1984-04-26	Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them
GB2080301B (en)	1984-04-18	Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
1996-10-31	RH	Patent void