IL63709A - Pyrazine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Pyrazine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL63709A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; pyrazine derivatives; pyrazine
Prior art date: 1980-09-02

Application number

IL63709A

Other languages

English (en)

Other versions

IL63709A0 (en

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-09-02

Filing date

1981-09-01

Publication date

1985-02-28

1981-09-01 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1981-12-31 Publication of IL63709A0 publication Critical patent/IL63709A0/xx

1985-02-28 Publication of IL63709A publication Critical patent/IL63709A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

IL63709A 1980-09-02 1981-09-01 Pyrazine derivatives,their preparation and pharmaceutical compositions containing them IL63709A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19803032994 DE3032994A1 (de)	1980-09-02	1980-09-02	Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel

Publications (2)

Publication Number	Publication Date
IL63709A0 IL63709A0 (en)	1981-12-31
IL63709A true IL63709A (en)	1985-02-28

Family

ID=6110937

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL63709A IL63709A (en)	1980-09-02	1981-09-01	Pyrazine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country	Link
US (2)	US4409220A (el)
EP (1)	EP0047412B1 (el)
JP (1)	JPS5777684A (el)
AR (1)	AR227683A1 (el)
AT (1)	ATE8630T1 (el)
AU (1)	AU7477281A (el)
CA (1)	CA1172631A (el)
DD (1)	DD201682A5 (el)
DE (2)	DE3032994A1 (el)
DK (1)	DK385381A (el)
ES (1)	ES8206525A1 (el)
FI (1)	FI812687L (el)
GB (1)	GB2084135B (el)
GR (1)	GR75003B (el)
HU (1)	HU185651B (el)
IL (1)	IL63709A (el)
NO (1)	NO812963L (el)
NZ (1)	NZ198225A (el)
PH (1)	PH17099A (el)
PT (1)	PT73608B (el)
YU (1)	YU210681A (el)
ZA (1)	ZA816046B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3032994A1 (de) *	1980-09-02	1982-04-22	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel
WO2007140213A1 (en) *	2006-05-26	2007-12-06	Forest Laboratories Holdings Limited	Pyridoazepine derivatives
EP2400961B1 (de)	2009-02-27	2017-11-22	Boehringer Ingelheim International GmbH	Arzneimittelkombinationen enthaltend pde4-inhibitoren und nsaids
US8877758B2 (en)	2010-04-08	2014-11-04	Boehringer Ingelheim International Gmbh	Combinations of medicaments, containing PDE4-inhibitors and EP4-receptor-antagonists

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1009477A (en)	1962-02-13	1965-11-10	Smith Kline French Lab	Novel process for preparing heterocyclic compounds
ES431307A1 (es) *	1973-11-16	1976-09-01	Thomae Gmbh Dr K	Procedimiento para la preparacion de nuevos derivados de quinoleina.
DE2357253A1 (de) *	1973-11-16	1975-05-22	Thomae Gmbh Dr K	Neue chinolinderivate
US4022779A (en) *	1974-07-25	1977-05-10	E. R. Squibb & Sons, Inc.	Amino derivatives of pyrido(3,4-b)pyrazine carboxylic acids and esters
DE2519258A1 (de) *	1975-04-30	1976-11-11	Thomae Gmbh Dr K	Neue chinoxaline
DE2617101A1 (de) *	1976-04-17	1977-11-17	Thomae Gmbh Dr K	Neue naphthyridine
IT7851496A0 (it) *	1977-10-31	1978-10-13	Sandoz Ag	Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
EP0008864A1 (en) *	1978-08-15	1980-03-19	FISONS plc	Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them
DE3032994A1 (de) *	1980-09-02	1982-04-22	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel

1980
- 1980-09-02 DE DE19803032994 patent/DE3032994A1/de not_active Withdrawn
1981
- 1981-08-19 DE DE8181106448T patent/DE3165064D1/de not_active Expired
- 1981-08-19 EP EP81106448A patent/EP0047412B1/de not_active Expired
- 1981-08-19 AT AT81106448T patent/ATE8630T1/de not_active IP Right Cessation
- 1981-08-27 US US06/297,024 patent/US4409220A/en not_active Expired - Fee Related
- 1981-08-27 DD DD81232842A patent/DD201682A5/de unknown
- 1981-08-31 FI FI812687A patent/FI812687L/fi not_active Application Discontinuation
- 1981-08-31 DK DK385381A patent/DK385381A/da not_active Application Discontinuation
- 1981-08-31 GR GR65913A patent/GR75003B/el unknown
- 1981-08-31 AU AU74772/81A patent/AU7477281A/en not_active Abandoned
- 1981-09-01 NO NO812963A patent/NO812963L/no unknown
- 1981-09-01 IL IL63709A patent/IL63709A/xx unknown
- 1981-09-01 NZ NZ198225A patent/NZ198225A/en unknown
- 1981-09-01 JP JP56137682A patent/JPS5777684A/ja active Pending
- 1981-09-01 CA CA000384970A patent/CA1172631A/en not_active Expired
- 1981-09-01 ES ES505095A patent/ES8206525A1/es not_active Expired
- 1981-09-01 PT PT73608A patent/PT73608B/pt unknown
- 1981-09-01 GB GB8126458A patent/GB2084135B/en not_active Expired
- 1981-09-01 ZA ZA816046A patent/ZA816046B/xx unknown
- 1981-09-01 YU YU02106/81A patent/YU210681A/xx unknown
- 1981-09-01 HU HU812524A patent/HU185651B/hu unknown
- 1981-09-02 AR AR286619A patent/AR227683A1/es active
- 1981-09-02 PH PH26132A patent/PH17099A/en unknown
1983
- 1983-06-06 US US06/501,437 patent/US4486433A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA1172631A (en)	1984-08-14
GR75003B (el)	1984-07-12
AR227683A1 (es)	1982-11-30
PH17099A (en)	1984-05-29
AU7477281A (en)	1982-03-11
HU185651B (en)	1985-03-28
EP0047412B1 (de)	1984-07-25
DE3165064D1 (en)	1984-08-30
NO812963L (no)	1982-03-03
US4409220A (en)	1983-10-11
EP0047412A1 (de)	1982-03-17
GB2084135A (en)	1982-04-07
ZA816046B (en)	1983-05-25
GB2084135B (en)	1984-08-22
NZ198225A (en)	1984-11-09
DE3032994A1 (de)	1982-04-22
ES505095A0 (es)	1982-08-16
IL63709A0 (en)	1981-12-31
ATE8630T1 (de)	1984-08-15
DK385381A (da)	1982-03-03
FI812687L (fi)	1982-03-03
JPS5777684A (en)	1982-05-15
YU210681A (en)	1983-10-31
US4486433A (en)	1984-12-04
DD201682A5 (de)	1983-08-03
PT73608B (de)	1983-10-19
PT73608A (de)	1981-10-01
ES8206525A1 (es)	1982-08-16

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