[go: up one dir, main page]

IL62021A0 - Pharmaceutical preparations containing poly-glycidyl-substituted n-hetero-cyclic compounds - Google Patents

Pharmaceutical preparations containing poly-glycidyl-substituted n-hetero-cyclic compounds

Info

Publication number
IL62021A0
IL62021A0 IL62021A IL6202181A IL62021A0 IL 62021 A0 IL62021 A0 IL 62021A0 IL 62021 A IL62021 A IL 62021A IL 6202181 A IL6202181 A IL 6202181A IL 62021 A0 IL62021 A0 IL 62021A0
Authority
IL
Israel
Prior art keywords
ring
substituted
following formula
heterocyclic
formula see
Prior art date
Application number
IL62021A
Original Assignee
Henkel Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19803003404 external-priority patent/DE3003404A1/en
Priority claimed from DE19803003357 external-priority patent/DE3003357A1/en
Priority claimed from DE19803003356 external-priority patent/DE3003356A1/en
Priority claimed from AT564480A external-priority patent/AT370729B/en
Application filed by Henkel Kgaa filed Critical Henkel Kgaa
Publication of IL62021A0 publication Critical patent/IL62021A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

For the contracting States : BE CH DE FR GB IT LI NL SE 1. Cytostatic medicinal preparations based on polyglycidyl-substituted N-heterocyclic organic ring compounds, characterized in that they contain in one heterocyclic ring or in two interconnected heterocyclic rings, which either have one or two ring members in common or are attached to one another by a bridge member, at least two ring segments corresponding to the following formula see diagramm : EP0033503,P26,F1 or at least one ring segment corresponding to the following formula see diagramm : EP0033503,P26,F2 in which the glycidyl residue corresponds to the following formula see diagramm : EP0033503,P26,F3 in which R is hydrogen or the methyl group, and in that, providing these ring segments are not themselves closed to form the ring, they further contain carbon and, optionally, nitrogen as ring-closing elements and in that they may contain halogens or unsubstituted hydrocarbon radicals containing no more than 8 C-atoms as further substituents on the heterocyclic rings, isocyanurates, urazoles and hydantoins being excluded as heterocycles and the polyglycidyl-substituted N-heterocycles present therein not exceeding a molecular weight of 1000. For the contracting State : AT 1. A process for the production of cytostatic medicinal preparation based on polyglicidyl-substituted N-heterocyclic organic ring compounds, characterized in that the polyglicidyl-substituted N-heterocyclic organic ring compounds contain in one heterocyclic ring or in two interconnected heterocyclic rings, which either have one or two ring members in common or are attached to one another by a bridge member, at least two ring segments corresponding to the following formula see diagramm : EP0033503,P29,F1 or at least one ring segment corresponding to the following formula see diagramm : EP0033503,P29,F2 in which the glycidyl residue corresponds to the following formula see diagramm : EP0033503,P29,F3 in which R is hydrogen or the methyl group, and in that, providing these ring segments are not themselves closed to form the ring, they further contain carbon and, optionally, nitrogen as ring-closing elements and in that they may contain halogens or unsubstituted hydrocarbon radicals containing no more than 8 C-atoms as further substituents on the heterocyclic rings, isocyanurates, urazoles and hydantoins being excluded as heterocycles and the polyglycidyl-substituted N-heterocycles present therein not exceeding a molecular weight of 1000.
IL62021A 1980-01-31 1981-01-30 Pharmaceutical preparations containing poly-glycidyl-substituted n-hetero-cyclic compounds IL62021A0 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE19803003404 DE3003404A1 (en) 1980-01-31 1980-01-31 Cytostatic agents contg. di:glycidyl bi:cyclic cpds. - e.g. N,N'-di:glycidyl-benzimidazolone
DE19803003357 DE3003357A1 (en) 1980-01-31 1980-01-31 Cytostatic agents contg. di:glycidyl-hydantoin derivs. - e.g. N,N'-di:glycidyl-furfurylidene-hydantoin or N,N'-di:glycidyl-5,5-di:methyl-hydantoin
DE19803003356 DE3003356A1 (en) 1980-01-31 1980-01-31 Cytostatic agents of di-, tri- or tetra-glycidyl-glycoluril derivs. - e.g. di:glycidyl-butyl-glycoluril or di:glycidyl-di:methyl-glycoluril
AT133180 1980-03-10
AT133080 1980-03-10
AT136580 1980-03-12
AT164980 1980-03-27
AT564480A AT370729B (en) 1980-11-17 1980-11-17 METHOD FOR PRODUCING NEW DIGLYCIDYLTRIAZINE COMPOUNDS

Publications (1)

Publication Number Publication Date
IL62021A0 true IL62021A0 (en) 1981-02-27

Family

ID=27569969

Family Applications (1)

Application Number Title Priority Date Filing Date
IL62021A IL62021A0 (en) 1980-01-31 1981-01-30 Pharmaceutical preparations containing poly-glycidyl-substituted n-hetero-cyclic compounds

Country Status (5)

Country Link
EP (1) EP0033503B1 (en)
AT (1) ATE22080T1 (en)
AU (1) AU543383B2 (en)
DE (1) DE3175281D1 (en)
IL (1) IL62021A0 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3102373A1 (en) * 1981-01-24 1982-08-26 Henkel KGaA, 4000 Düsseldorf "NEW N-SUBSTITUTED POLYGLYCIDYL-URAZOLE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS
DE3131396A1 (en) * 1981-08-07 1983-03-24 Henkel KGaA, 4000 Düsseldorf "NEW DIGLYCIDYL-PTERIDINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS WITH A CYTOSTATIC EFFECT"
DE3131365A1 (en) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf NEW DIGLYCIDYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN PHARMACEUTICAL PREPARATIONS WITH CYTOSTATIC EFFECTIVENESS
DE3133077A1 (en) * 1981-08-21 1983-03-10 Henkel KGaA, 4000 Düsseldorf NEW 1,3,2-OXAZAPHOSPHORINE COMPOUNDS CONTAINING NEW CYTOSTATICALLY EFFECTIVE EPOXY GROUPS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN PHARMACEUTICAL PREPARATIONS
DE3330640A1 (en) * 1983-08-25 1985-03-14 Henkel KGaA, 4000 Düsseldorf METHOD FOR ADDING ACIDS TO GLYCIDYL COMPOUNDS
CN107614564B (en) 2015-03-04 2020-04-14 爱沃特株式会社 Thermal expansion modifier, use thereof as thermal expansion modifier, and thermosetting resin composition
RU2769828C1 (en) * 2021-12-28 2022-04-06 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации Uracil derivatives with antiviral activity against sars-cov-2

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH471811A (en) * 1966-06-23 1969-04-30 Ciba Geigy Process for the preparation of water-soluble N, N'-diglycidyl compounds
DE2907349C2 (en) * 1979-02-24 1982-09-16 Henkel KGaA, 4000 Düsseldorf Medicines with cytostatic activity

Also Published As

Publication number Publication date
EP0033503A2 (en) 1981-08-12
AU6676181A (en) 1981-08-06
DE3175281D1 (en) 1986-10-16
EP0033503B1 (en) 1986-09-10
ATE22080T1 (en) 1986-09-15
EP0033503A3 (en) 1982-01-13
AU543383B2 (en) 1985-04-18

Similar Documents

Publication Publication Date Title
HU9500006D0 (en) Heterocyclic compounds as pharmaceutical
AU3867985A (en) Nitromethylene derivatives of nitrogen containing heterocyclic compounds
IL62021A0 (en) Pharmaceutical preparations containing poly-glycidyl-substituted n-hetero-cyclic compounds
ATE7918T1 (en) CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR INTERMEDIATE PRODUCTS.
SE7712630L (en) PROCEDURE FOR THE PREPARATION OF O-ALKYLATED HYDROXYLAMINES
ES8604543A1 (en) Piperazine derivatives with anticholinergic and/or antihistaminic activity
ES471458A1 (en) Bicyclic thiadiaza compounds, process and intermediates for their preparation, and medicaments containing these compounds or the intermediates.
FR2372187A1 (en)
IL89942A (en) Heterotetracyclic lactam derivatives, their preparation and pharmaceutical compositions containing them
DK158979C (en) AMINOPROPANOL DERIVATIVES OF SUBSTITUTED 2-HYDROXYPROPIOPHENONES AND THERAPEUTIC PREPARATIONS WITH CONTENTS
AU546679B2 (en) Hydrogenated 1,4 thiazepine (thiazine) dione derivatives
NZ240272A (en) Piperazine derivatives; pharmaceutical compositions and preparatory processes
EP0213450A3 (en) Aminoacyl derivatives of 4,9-dihydro-10h-pyridoû3,2-b¨-thieno-û3,2-e¨û1,4¨diazepinone and of 4,9-dihydro-10h-pyridoû3,2-b¨-thienoû3,4-e¨û1,4¨diazepinone, their preparation and pharmaceutical compositions containing them
GB1080680A (en) Process for the preparation of iminopyrrolidine derivatives
EP0294828A3 (en) Mitomycin analogs, a process for preparing them and pharmaceutical compositions
IL84084A0 (en) Quarternized nitrogen containing compounds
KR860004040A (en) Method for preparing 3,4-diazole derivative
ATE42748T1 (en) CONDENSED HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE.
ES427763A1 (en) Disperse dyestuffs