IL61212A - Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters,their preparation and pharmaceutical compositions containing them - Google Patents
Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL61212A IL61212A IL61212A IL6121280A IL61212A IL 61212 A IL61212 A IL 61212A IL 61212 A IL61212 A IL 61212A IL 6121280 A IL6121280 A IL 6121280A IL 61212 A IL61212 A IL 61212A
- Authority
- IL
- Israel
- Prior art keywords
- pyrrole
- dialkyl
- hydroxy
- preparation
- carboxylic acid
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 150000003053 piperidines Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792941597 DE2941597A1 (de) | 1979-10-13 | 1979-10-13 | Piperidinderivate von 4,5-dialkyl-3-hydroxy-pyrrol-2-carbonsaeureestern, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL61212A0 IL61212A0 (en) | 1980-12-31 |
IL61212A true IL61212A (en) | 1983-09-30 |
Family
ID=6083464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL61212A IL61212A (en) | 1979-10-13 | 1980-10-06 | Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters,their preparation and pharmaceutical compositions containing them |
Country Status (18)
Country | Link |
---|---|
US (1) | US4315939A (es) |
EP (1) | EP0027928B1 (es) |
JP (1) | JPS5663956A (es) |
AT (1) | ATE2746T1 (es) |
AU (1) | AU532982B2 (es) |
CA (1) | CA1155124A (es) |
CS (1) | CS214759B2 (es) |
DE (2) | DE2941597A1 (es) |
DK (1) | DK430380A (es) |
ES (1) | ES495831A0 (es) |
FI (1) | FI70013C (es) |
HU (1) | HU184936B (es) |
IE (1) | IE50796B1 (es) |
IL (1) | IL61212A (es) |
NO (1) | NO803047L (es) |
SU (1) | SU957768A3 (es) |
YU (1) | YU262380A (es) |
ZA (1) | ZA806282B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0076072B1 (en) * | 1981-09-24 | 1987-05-13 | BEECHAM - WUELFING GmbH & Co. KG | Sulphonamides |
US4558129A (en) * | 1983-05-18 | 1985-12-10 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade |
US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
AU4977899A (en) * | 1998-07-27 | 2000-02-21 | Eli Lilly And Company | Treatment of anxiety disorders |
US6242450B1 (en) | 1998-07-27 | 2001-06-05 | Eli Lilly And Company | 5-HT1F antagonists |
UY33388A (es) * | 2010-05-17 | 2011-12-01 | Glaxo Group Ltd | Nuevos procesos para la preparacion de compuestos de pirimidinona |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1527E (fr) * | 1902-08-20 | 1903-08-12 | Hermann Hilbert | Procédé pour extrait la gélatine et la colle des os |
DE1720033A1 (de) * | 1966-03-02 | 1971-05-19 | Yoshitomi Pharmaceutical | Neue Indolderivate und Verfahren zu ihrer Herstellung |
CH489497A (de) * | 1967-01-25 | 1970-04-30 | Geigy Ag J R | Verfahren zur Herstellung von neuen Indolderivaten |
US3860609A (en) * | 1969-05-27 | 1975-01-14 | Novo Terapeutisk Labor As | 3-aminoalkyloxyindoles |
DE2630152A1 (de) * | 1976-07-05 | 1978-01-19 | Cassella Farbwerke Mainkur Ag | Derivate des 1-phenoxy-propan-2-ols- und verfahren zu ihrer herstellung |
-
1979
- 1979-10-13 DE DE19792941597 patent/DE2941597A1/de not_active Withdrawn
-
1980
- 1980-09-19 FI FI802960A patent/FI70013C/fi not_active IP Right Cessation
- 1980-10-06 IL IL61212A patent/IL61212A/xx unknown
- 1980-10-06 US US06/194,441 patent/US4315939A/en not_active Expired - Lifetime
- 1980-10-07 DE DE8080106069T patent/DE3062300D1/de not_active Expired
- 1980-10-07 CA CA000361718A patent/CA1155124A/en not_active Expired
- 1980-10-07 AT AT80106069T patent/ATE2746T1/de not_active IP Right Cessation
- 1980-10-07 EP EP80106069A patent/EP0027928B1/de not_active Expired
- 1980-10-10 IE IE2102/80A patent/IE50796B1/en unknown
- 1980-10-10 ES ES495831A patent/ES495831A0/es active Granted
- 1980-10-10 SU SU802990879A patent/SU957768A3/ru active
- 1980-10-10 NO NO803047A patent/NO803047L/no unknown
- 1980-10-10 DK DK430380A patent/DK430380A/da not_active Application Discontinuation
- 1980-10-11 JP JP14114780A patent/JPS5663956A/ja active Granted
- 1980-10-13 ZA ZA00806282A patent/ZA806282B/xx unknown
- 1980-10-13 AU AU63204/80A patent/AU532982B2/en not_active Ceased
- 1980-10-13 CS CS806922A patent/CS214759B2/cs unknown
- 1980-10-13 HU HU802484A patent/HU184936B/hu not_active IP Right Cessation
- 1980-10-13 YU YU02623/80A patent/YU262380A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HU184936B (en) | 1984-11-28 |
FI70013C (fi) | 1986-09-12 |
ES8200363A1 (es) | 1981-11-01 |
CA1155124A (en) | 1983-10-11 |
DK430380A (da) | 1981-04-14 |
ATE2746T1 (de) | 1983-03-15 |
IL61212A0 (en) | 1980-12-31 |
JPS648632B2 (es) | 1989-02-14 |
US4315939A (en) | 1982-02-16 |
CS214759B2 (en) | 1982-05-28 |
FI802960A (fi) | 1981-04-14 |
EP0027928B1 (de) | 1983-03-09 |
AU6320480A (en) | 1981-04-16 |
YU262380A (en) | 1983-01-21 |
SU957768A3 (ru) | 1982-09-07 |
DE2941597A1 (de) | 1981-04-23 |
DE3062300D1 (en) | 1983-04-14 |
IE50796B1 (en) | 1986-07-23 |
EP0027928A3 (en) | 1981-05-20 |
AU532982B2 (en) | 1983-10-20 |
ZA806282B (en) | 1981-10-28 |
ES495831A0 (es) | 1981-11-01 |
NO803047L (no) | 1981-04-14 |
EP0027928A2 (de) | 1981-05-06 |
JPS5663956A (en) | 1981-05-30 |
IE802102L (en) | 1981-04-13 |
FI70013B (fi) | 1986-01-31 |
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