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IL60161A - N-hexahydroazocinylidene-n-phenylcarboximidamides,their production and pharmaceutical compositions containing them - Google Patents

N-hexahydroazocinylidene-n-phenylcarboximidamides,their production and pharmaceutical compositions containing them

Info

Publication number
IL60161A
IL60161A IL60161A IL6016180A IL60161A IL 60161 A IL60161 A IL 60161A IL 60161 A IL60161 A IL 60161A IL 6016180 A IL6016180 A IL 6016180A IL 60161 A IL60161 A IL 60161A
Authority
IL
Israel
Prior art keywords
phenylcarboximidamides
hexahydroazocinylidene
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL60161A
Other languages
English (en)
Other versions
IL60161A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL60161A0 publication Critical patent/IL60161A0/xx
Publication of IL60161A publication Critical patent/IL60161A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL60161A 1979-05-29 1980-05-26 N-hexahydroazocinylidene-n-phenylcarboximidamides,their production and pharmaceutical compositions containing them IL60161A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH499379 1979-05-29

Publications (2)

Publication Number Publication Date
IL60161A0 IL60161A0 (en) 1980-07-31
IL60161A true IL60161A (en) 1984-05-31

Family

ID=4286083

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60161A IL60161A (en) 1979-05-29 1980-05-26 N-hexahydroazocinylidene-n-phenylcarboximidamides,their production and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4626537A (xx)
EP (1) EP0020303B1 (xx)
JP (1) JPS55160764A (xx)
KR (2) KR840002309B1 (xx)
AT (1) ATE15189T1 (xx)
CS (2) CS220336B2 (xx)
CY (1) CY1442A (xx)
DD (1) DD151163A5 (xx)
DE (1) DE3071029D1 (xx)
DK (1) DK156059B (xx)
ES (1) ES491926A0 (xx)
FI (1) FI75154C (xx)
GR (1) GR68377B (xx)
HK (1) HK80788A (xx)
HU (1) HU183145B (xx)
IL (1) IL60161A (xx)
NO (1) NO153850C (xx)
PL (2) PL124028B1 (xx)
PT (1) PT71313A (xx)
SG (1) SG33688G (xx)
SU (2) SU1222191A3 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8312665D0 (en) * 1983-05-09 1983-06-15 Ici Plc 4,4'-alkylenedipiperidine derivatives
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
DK0690851T3 (da) * 1993-03-23 1999-11-08 Astra Ab Guanidin-derivater, som er anvendelige til behandling
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
AU2003245325A1 (en) * 2002-05-23 2003-12-12 Chiron Corporation Substituted quinazolinone compounds
JP2007501861A (ja) 2003-05-23 2007-02-01 カイロン コーポレイション Mc4−rアゴニストとしてのグアニジノ置換キナゾリノン化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH513848A (de) * 1967-02-27 1971-10-15 Hoffmann La Roche Verfahren zur Herstellung von Pyrrolinverbindungen
DE2205744A1 (de) * 1972-02-08 1973-08-09 Thomae Gmbh Dr K Neue durch einen guanidinylidenrest substituierte heterocyclen und verfahren zu ihrer herstellung
US3840524A (en) * 1973-04-25 1974-10-08 Richardson Merrell Inc Alpha-cycloalkylbenzyl lactamimides
US4126612A (en) * 1973-08-09 1978-11-21 Eugene O. Retter Substituted cycloalkyl lactamimides
US4211867A (en) * 1976-03-19 1980-07-08 Mcneil Laboratories, Incorporated Nitrogen heterocyclic carboximidamide compounds
CS225804B2 (cs) * 1976-03-19 1984-02-13 Mcneilab Inc Způsob výroby heterocyklických derivátů guanidinu
NZ183570A (en) * 1976-03-19 1979-06-08 Mcneilab Inc Heterocyclic guanidine derivatives, having anti-secretory and hypogliycaemic activity

Also Published As

Publication number Publication date
FI75154C (fi) 1988-05-09
EP0020303B1 (de) 1985-08-28
EP0020303A1 (de) 1980-12-10
ES8103031A1 (es) 1981-02-16
FI801690A (fi) 1980-11-30
KR830002716A (ko) 1983-05-30
GR68377B (xx) 1981-12-28
FI75154B (fi) 1988-01-29
US4626537A (en) 1986-12-02
PL124028B1 (en) 1982-12-31
CS220327B2 (en) 1983-03-25
NO153850B (no) 1986-02-24
NO153850C (no) 1986-06-04
HU183145B (en) 1984-04-28
KR840002309B1 (ko) 1984-12-17
DE3071029D1 (en) 1985-10-03
ATE15189T1 (de) 1985-09-15
ES491926A0 (es) 1981-02-16
CY1442A (en) 1989-03-10
KR840002310B1 (ko) 1984-12-17
NO801585L (no) 1980-12-01
SU1227111A3 (ru) 1986-04-23
PT71313A (de) 1980-06-01
DD151163A5 (de) 1981-10-08
CS220336B2 (en) 1983-03-25
IL60161A0 (en) 1980-07-31
JPS55160764A (en) 1980-12-13
PL224523A1 (xx) 1981-02-13
SU1222191A3 (ru) 1986-03-30
DK156059B (da) 1989-06-19
PL126790B1 (en) 1983-08-31
SG33688G (en) 1989-01-27
HK80788A (en) 1988-10-14
DK229480A (da) 1980-11-30

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