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IL54531A0 - Improvements in or relating to cephalosporin antibiotics - Google Patents

Improvements in or relating to cephalosporin antibiotics

Info

Publication number
IL54531A0
IL54531A0 IL54531A IL5453178A IL54531A0 IL 54531 A0 IL54531 A0 IL 54531A0 IL 54531 A IL54531 A IL 54531A IL 5453178 A IL5453178 A IL 5453178A IL 54531 A0 IL54531 A0 IL 54531A0
Authority
IL
Israel
Prior art keywords
relating
cephalosporin antibiotics
cephalosporin
antibiotics
Prior art date
Application number
IL54531A
Other versions
IL54531A (en
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of IL54531A0 publication Critical patent/IL54531A0/en
Publication of IL54531A publication Critical patent/IL54531A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/06Preparation of esters of carbonic or haloformic acids from organic carbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00Preparation of esters of carbonic or haloformic acids
    • C07C68/02Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL54531A 1977-04-19 1978-04-18 Carbonic acis esters of cefuroxime, their preparation and pharmaceutical compsitions containing them IL54531A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB16202/77A GB1598568A (en) 1977-04-19 1977-04-19 Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid

Publications (2)

Publication Number Publication Date
IL54531A0 true IL54531A0 (en) 1978-07-31
IL54531A IL54531A (en) 1981-07-31

Family

ID=10073017

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54531A IL54531A (en) 1977-04-19 1978-04-18 Carbonic acis esters of cefuroxime, their preparation and pharmaceutical compsitions containing them

Country Status (20)

Country Link
JP (1) JPS53132592A (en)
KR (1) KR840000081B1 (en)
AT (1) AT363183B (en)
AU (1) AU521098B2 (en)
BE (1) BE866093A (en)
CA (1) CA1093068A (en)
CH (1) CH639096A5 (en)
DE (1) DE2816873A1 (en)
DK (1) DK147513C (en)
ES (1) ES468895A1 (en)
FR (1) FR2387988A1 (en)
GB (1) GB1598568A (en)
IE (1) IE46726B1 (en)
IL (1) IL54531A (en)
IT (1) IT1104842B (en)
NL (1) NL7804097A (en)
NZ (1) NZ186998A (en)
SE (1) SE433748B (en)
YU (1) YU90978A (en)
ZA (1) ZA782211B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482587A1 (en) * 1980-05-14 1981-11-20 Poudres & Explosifs Ste Nale PROCESS FOR THE SYNTHESIS OF A-CHLORINATED CHLOROFORMIATES AND NEW A-CHLORINATED CHLOROFORMIATES
GR76477B (en) * 1981-03-23 1984-08-10 Kyoto Pharma Ind
IL68992A (en) * 1982-06-29 1991-06-10 Astra Laekemedel Ab Alpha-bromo diethyl carbonate and process for the preparation of ethoxycarbonyloxy esters of penicillanic acids
IT1190897B (en) * 1982-06-29 1988-02-24 Opos Biochimica Srl PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
GB2123821B (en) * 1982-06-29 1987-04-23 Astra Laekemedel Ab At-halogeno diethyl carbonates and their use in the preparation of antibiotics
FR2532933B1 (en) * 1982-06-29 1987-11-13 Astra Laekemedel Ab IMPROVEMENTS IN THE PREPARATION OF ANTIBIOTICS
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
IL67623A (en) * 1983-01-05 1984-09-30 Teva Pharma 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it
GB8320521D0 (en) * 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
FR2551058B1 (en) * 1983-08-26 1986-09-26 Poudres & Explosifs Ste Nale PROCESS FOR THE PREPARATION OF A-CHLORINATED CHLOROFORMIATES
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
US4612143A (en) * 1984-09-17 1986-09-16 Societe Nationale Des Poudres Et Explosifs Process for the preparation of fluoroformates
US5202454A (en) * 1986-07-11 1993-04-13 Societe Nationale Des Poudres Et Explosifs Process for the manufacture of 1-bromoalkyl hydrocarbyl carbonates
KR100342944B1 (en) 1999-11-08 2002-07-02 민경윤 Method for preparing highly pure cefpodoxime proxetil
GB0301938D0 (en) * 2003-01-28 2003-02-26 Biochemie Gmbh Organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
CA1093549A (en) * 1976-02-16 1981-01-13 Michael Gregson Cephalosporin antibiotics
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics

Also Published As

Publication number Publication date
CH639096A5 (en) 1983-10-31
NL7804097A (en) 1978-10-23
ATA274878A (en) 1980-12-15
IE780760L (en) 1978-10-19
DK147513C (en) 1985-03-18
IE46726B1 (en) 1983-09-07
IT7848941A0 (en) 1978-04-18
IL54531A (en) 1981-07-31
ZA782211B (en) 1979-04-25
SE7804400L (en) 1978-10-20
CA1093068A (en) 1981-01-06
DE2816873A1 (en) 1978-11-02
KR830000246A (en) 1983-03-30
ES468895A1 (en) 1978-12-01
GB1598568A (en) 1981-09-23
YU90978A (en) 1983-01-21
AU3518778A (en) 1979-10-25
SE433748B (en) 1984-06-12
AT363183B (en) 1981-07-10
DK168778A (en) 1978-10-20
BE866093A (en) 1978-10-18
FR2387988B1 (en) 1982-06-11
DK147513B (en) 1984-09-10
FR2387988A1 (en) 1978-11-17
NZ186998A (en) 1981-05-01
AU521098B2 (en) 1982-03-18
IT1104842B (en) 1985-10-28
JPS53132592A (en) 1978-11-18
KR840000081B1 (en) 1984-02-08

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