IL52645A0 - Optically active n-substituted pyrrolidines and stereospecific synthesis thereof - Google Patents

Optically active n-substituted pyrrolidines and stereospecific synthesis thereof

Info

Publication number: IL52645A0
Authority: IL; Israel
Prior art keywords: optically active; stereospecific synthesis; substituted pyrrolidines; pyrrolidines; substituted
Prior art date: 1976-08-05

Application number

IL7752645A

Other versions

IL52645A (en

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-08-05

Filing date

1977-08-02

Publication date

1977-10-31

1976-08-05 Priority claimed from FR7623910A external-priority patent/FR2360572A1/en

1976-11-25 Priority claimed from FR7635476A external-priority patent/FR2372157A1/en

1977-06-24 Priority claimed from FR7719391A external-priority patent/FR2395261A2/en

1977-08-02 Application filed by Synthelabo filed Critical Synthelabo

1977-10-31 Publication of IL52645A0 publication Critical patent/IL52645A0/en

1980-02-29 Publication of IL52645A publication Critical patent/IL52645A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyrrole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL52645A 1976-08-05 1977-08-02 Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides IL52645A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR7623910A FR2360572A1 (en)	1976-08-05	1976-08-05	Optically active (2)-amino-methyl-(1)-substd. pyrrolidine derivs. - intermediates for benzoylamino-methyl-pyrrolidine pharmaceuticals
FR7635476A FR2372157A1 (en)	1976-11-25	1976-11-25	Optically active (2)-amino-methyl-(1)-substd. pyrrolidine derivs. - intermediates for benzoylamino-methyl-pyrrolidine pharmaceuticals
FR7719391A FR2395261A2 (en)	1977-06-24	1977-06-24	Optically active (2)-amino-methyl-(1)-substd. pyrrolidine derivs. - intermediates for benzoylamino-methyl-pyrrolidine pharmaceuticals

Publications (2)

Publication Number	Publication Date
IL52645A0 true IL52645A0 (en)	1977-10-31
IL52645A IL52645A (en)	1980-02-29

Family

ID=27250658

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL52645A IL52645A (en)	1976-08-05	1977-08-02	Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides

Country Status (20)

Country	Link
JP (1)	JPS5325563A (en)
AT (1)	AT364818B (en)
AU (1)	AU510454B2 (en)
CA (1)	CA1083586A (en)
CH (2)	CH624933A5 (en)
DE (1)	DE2735036C2 (en)
DK (1)	DK350377A (en)
ES (1)	ES461342A1 (en)
FI (1)	FI772363A (en)
GB (1)	GB1555890A (en)
GR (1)	GR63594B (en)
IE (1)	IE45544B1 (en)
IL (1)	IL52645A (en)
IT (1)	IT1085696B (en)
LU (1)	LU77917A1 (en)
NL (1)	NL7708571A (en)
NO (2)	NO772745L (en)
NZ (1)	NZ184832A (en)
PT (1)	PT66894B (en)
SE (2)	SE7708902L (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1095415B (en) *	1978-02-16	1985-08-10	Ravizza Spa	PROCESS FOR THE PRODUCTION OF AN OPTICALLY ACTIVE BENZAMIDE, OPTICALLY ACTIVE BENZAMIDE SO OBTAINED AND COMPOSITIONS
IT1141095B (en) *	1980-11-27	1986-10-01	Ravizza Spa	RESOLUTION PROCESS OF THE SULPYRID RACEMA
SE8602339D0 (en) *	1986-05-22	1986-05-22	Astra Laekemedel Ab	AND EFFECTIVE STEREOCONSERVATIVE SYNTHESIS OF 1-SUBSTITUTED (S) - AND (R) -2-AMINOMETHYLPYRROLIDINES
DE4425070A1 (en)	1994-07-15	1996-01-18	Degussa	Process for the preparation of optically active l-substituted 2- (aminomethyl) pyrrolidines
US7531673B2 (en) *	2004-02-18	2009-05-12	Dr. Reddy's Laboratories Limited	Preparation of amino acid amides
CN104086475B (en) *	2014-07-15	2016-10-05	苏州天马精细化学品股份有限公司	A kind of preparation method of N-benzyloxycarbonyl group-L-prolineamide
CN106045869A (en) *	2016-06-30	2016-10-26	宜兴市前成生物有限公司	Method for preparing DL-glutamic acid
CN117185977A (en) *	2023-09-20	2023-12-08	江苏阿尔法药业股份有限公司	A kind of preparation method of amisulpride intermediate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1528014A (en) *	1967-04-24	1968-06-07	Ile De France	Process for the preparation of optical isomers of ethyl-1, aminomethyl-2-pyrrolidine
CH507938A (en) *	1968-08-01	1971-05-31	Ile De France	Process for the preparation of heterocyclic benzamides

1977
- 1977-08-02 IL IL52645A patent/IL52645A/en unknown
- 1977-08-03 DE DE2735036A patent/DE2735036C2/en not_active Expired
- 1977-08-03 GR GR54101A patent/GR63594B/en unknown
- 1977-08-03 NZ NZ184832A patent/NZ184832A/en unknown
- 1977-08-03 NL NL7708571A patent/NL7708571A/en not_active Application Discontinuation
- 1977-08-04 GB GB32790/77A patent/GB1555890A/en not_active Expired
- 1977-08-04 ES ES461342A patent/ES461342A1/en not_active Expired
- 1977-08-04 LU LU77917A patent/LU77917A1/xx unknown
- 1977-08-04 IE IE1633/77A patent/IE45544B1/en unknown
- 1977-08-04 NO NO772745A patent/NO772745L/en unknown
- 1977-08-04 FI FI772363A patent/FI772363A/fi not_active Application Discontinuation
- 1977-08-04 AU AU27641/77A patent/AU510454B2/en not_active Expired
- 1977-08-04 SE SE7708902A patent/SE7708902L/en not_active Application Discontinuation
- 1977-08-04 JP JP9404477A patent/JPS5325563A/en active Pending
- 1977-08-04 CH CH959477A patent/CH624933A5/fr not_active IP Right Cessation
- 1977-08-04 DK DK350377A patent/DK350377A/en not_active Application Discontinuation
- 1977-08-04 PT PT66894A patent/PT66894B/en unknown
- 1977-08-04 CA CA284,104A patent/CA1083586A/en not_active Expired
- 1977-08-04 IT IT26497/77A patent/IT1085696B/en active
- 1977-08-05 AT AT0577377A patent/AT364818B/en not_active IP Right Cessation
1980
- 1980-12-22 SE SE8009074A patent/SE8009074L/en not_active Application Discontinuation
1981
- 1981-01-06 CH CH4181A patent/CH626341A5/en not_active IP Right Cessation
- 1981-08-25 NO NO812871A patent/NO812871L/en unknown

Also Published As

Publication number	Publication date
NZ184832A (en)	1979-11-01
DE2735036C2 (en)	1983-10-13
AT364818B (en)	1981-11-25
ATA577377A (en)	1981-04-15
FI772363A (en)	1978-02-06
IE45544B1 (en)	1982-09-22
AU2764177A (en)	1979-02-08
SE7708902L (en)	1978-02-06
SE8009074L (en)	1980-12-22
DK350377A (en)	1978-02-06
CH626341A5 (en)	1981-11-13
JPS5325563A (en)	1978-03-09
IT1085696B (en)	1985-05-28
DE2735036A1 (en)	1978-02-16
PT66894A (en)	1977-09-01
PT66894B (en)	1979-01-26
GB1555890A (en)	1979-11-14
CA1083586A (en)	1980-08-12
IE45544L (en)	1978-02-05
IL52645A (en)	1980-02-29
CH624933A5 (en)	1981-08-31
GR63594B (en)	1979-11-26
AU510454B2 (en)	1980-06-26
LU77917A1 (en)	1977-11-14
NL7708571A (en)	1978-02-07
NO812871L (en)	1978-02-07
NO772745L (en)	1978-02-07
ES461342A1 (en)	1978-06-01

Publication	Publication Date	Title
ZA77313B (en)	1977-11-30	Proline derivatives and related compounds
NZ190589A (en)	1983-04-12	N-(heterocyclicaminocarbonyl)-arylsulphonamides
PH15710A (en)	1983-03-14	1-(4'-acylamino-phenyl)-2-amino-ethanols and salts thereof
ZA7731B (en)	1978-02-22	1-(substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)-hydrazines and derivatives thereof
JPS52105206A (en)	1977-09-03	Novel crystal form of 224422froylpiperazinee11il44aminoo6 77dimethoxychinazolin hydrochloride
IL52645A0 (en)	1977-10-31	Optically active n-substituted pyrrolidines and stereospecific synthesis thereof
AU509015B2 (en)	1980-04-17	2-benzyl pyrrolidines
NZ184263A (en)	1979-12-11	N-(amino-alkyl-amino)-benzamides and pharmaceutical compositions
GB2023002B (en)	1982-11-24	Pharmarceutically active cyclohexyl cyrboxylic acods and amides
JPS5551064A (en)	1980-04-14	Novel aryloxazolidinoneoxazolidinethione pyrrolidinonepyrrolidine and thiazolidinone their manufacture and their therapeutic application
HK17880A (en)	1980-04-11	N-(1'-allyl-2'-pyrrolidylmethyl)-2-3-dimethoxy-5-sulphamoylbenzamide and derivatives
GB2020648B (en)	1982-07-21	Dervitatives of pyrrolidine and piperidinecarboxaldehyde
AU516038B2 (en)	1981-05-14	l-SUBSTITUTED-3(w-AMINOALKYL) PYRROLIDINES
PT67585B (en)	1979-11-12	Azacycloalkanes azacycloalkenes and derivatives thereof
GB1523088A (en)	1978-08-31	2 - phenyl - 2 - carboxyethyl 1 - (p - chlorobenzoyl) - 5-methoxy - 2 - methyl - 3 - indolylacetate and process for the preparation thereof
AU3906178A (en)	1980-02-21	N-(4-pyazolidinyl)-benzamide derivatives
ZA774743B (en)	1978-06-28	Stereospecific synthesis of n-substituted pyrrolidines
JPS543056A (en)	1979-01-11	Novel prostacycline analogue and chemical synthesis
GB2048860B (en)	1982-12-15	N - (4 - azido - 5 - (2 - ethoxyethyl) - 6-phenyl - 2 - pyrimidinyl)acetamide and congeners
AU517816B2 (en)	1981-08-27	N-substituted benzothiazolines
ZA777252B (en)	1977-12-28	Direct synthesis of optically active 2-aminobutanols
JPS5298114A (en)	1977-08-17	Block for ridge and levee
JPS5315364A (en)	1978-02-13	Preparation of optical active 11methyll 22betaahydoxyethylpyrrolidine
AU511540B2 (en)	1980-08-21	N-(2-aminocyclohepty)-n-alkanoylanilides
GB1557867A (en)	1979-12-12	Transducers and parts therefor