IL297877A - צורות פולימורפיות של (r)-אוקסיבוטינין הידרוכלוריד - Google Patents
צורות פולימורפיות של (r)-אוקסיבוטינין הידרוכלורידInfo
- Publication number
- IL297877A IL297877A IL297877A IL29787722A IL297877A IL 297877 A IL297877 A IL 297877A IL 297877 A IL297877 A IL 297877A IL 29787722 A IL29787722 A IL 29787722A IL 297877 A IL297877 A IL 297877A
- Authority
- IL
- Israel
- Prior art keywords
- degrees
- degree
- oxybutynin
- crystalline form
- solid crystalline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063020301P | 2020-05-05 | 2020-05-05 | |
| US202163136691P | 2021-01-13 | 2021-01-13 | |
| PCT/US2021/030571 WO2021226020A1 (en) | 2020-05-05 | 2021-05-04 | Polymorphic forms of (r)-oxybutynin hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL297877A true IL297877A (he) | 2023-01-01 |
Family
ID=84324668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL297877A IL297877A (he) | 2020-05-05 | 2021-05-04 | צורות פולימורפיות של (r)-אוקסיבוטינין הידרוכלוריד |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230286900A1 (he) |
| EP (1) | EP4146621A1 (he) |
| JP (1) | JP2023524783A (he) |
| KR (1) | KR20230008120A (he) |
| CN (1) | CN115667205A (he) |
| AU (1) | AU2021268618A1 (he) |
| BR (1) | BR112022022292A2 (he) |
| CA (1) | CA3177654A1 (he) |
| CO (1) | CO2022016965A2 (he) |
| CR (1) | CR20220617A (he) |
| IL (1) | IL297877A (he) |
| MX (1) | MX2022013823A (he) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562368B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers |
| AU5596600A (en) * | 2000-06-07 | 2001-12-17 | Bridge Pharma Inc | Treating smooth muscle hyperactivity with (r)-oxybutynin and (r)- desethyloxybutynin |
| US20110087042A1 (en) * | 2008-02-04 | 2011-04-14 | Matrix Laboratories Limited | Crystalline oxybutynin and process for preparing the same |
| EP2938329A4 (en) * | 2012-12-27 | 2016-08-10 | Microdose Therapeutx Inc | METHODS AND COMPOSITIONS FOR OXYBUTYNINE ADMINISTRATION |
| CN104370760B (zh) * | 2013-11-29 | 2016-06-01 | 江苏汉邦科技有限公司 | 模拟移动床色谱拆分奥昔布宁对映体的方法 |
-
2021
- 2021-05-04 CN CN202180038499.3A patent/CN115667205A/zh active Pending
- 2021-05-04 KR KR1020227040332A patent/KR20230008120A/ko active Pending
- 2021-05-04 EP EP21727332.5A patent/EP4146621A1/en active Pending
- 2021-05-04 BR BR112022022292A patent/BR112022022292A2/pt unknown
- 2021-05-04 AU AU2021268618A patent/AU2021268618A1/en active Pending
- 2021-05-04 MX MX2022013823A patent/MX2022013823A/es unknown
- 2021-05-04 US US17/923,284 patent/US20230286900A1/en active Pending
- 2021-05-04 CR CR20220617A patent/CR20220617A/es unknown
- 2021-05-04 CA CA3177654A patent/CA3177654A1/en active Pending
- 2021-05-04 IL IL297877A patent/IL297877A/he unknown
- 2021-05-04 JP JP2022567347A patent/JP2023524783A/ja active Pending
-
2022
- 2022-11-26 CO CONC2022/0016965A patent/CO2022016965A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4146621A1 (en) | 2023-03-15 |
| CN115667205A (zh) | 2023-01-31 |
| CO2022016965A2 (es) | 2022-12-09 |
| KR20230008120A (ko) | 2023-01-13 |
| CA3177654A1 (en) | 2021-11-11 |
| AU2021268618A1 (en) | 2022-12-15 |
| MX2022013823A (es) | 2023-01-11 |
| BR112022022292A2 (pt) | 2022-12-20 |
| JP2023524783A (ja) | 2023-06-13 |
| CR20220617A (es) | 2023-02-09 |
| US20230286900A1 (en) | 2023-09-14 |
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