IL192773A0 - Microparticulate pharmaceutical forms resistant to immediate release of the active ingredient in the presence of alcohol - Google Patents
Microparticulate pharmaceutical forms resistant to immediate release of the active ingredient in the presence of alcoholInfo
- Publication number
- IL192773A0 IL192773A0 IL192773A IL19277308A IL192773A0 IL 192773 A0 IL192773 A0 IL 192773A0 IL 192773 A IL192773 A IL 192773A IL 19277308 A IL19277308 A IL 19277308A IL 192773 A0 IL192773 A0 IL 192773A0
- Authority
- IL
- Israel
- Prior art keywords
- alcohol
- active ingredient
- immediate release
- pharmaceutical forms
- forms resistant
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0650566A FR2897267A1 (en) | 2006-02-16 | 2006-02-16 | MULTIMICROPARTICULAR PHARMACEUTICAL FORMS FOR PER OS ADMINISTRATION |
| PCT/EP2007/051528 WO2007093642A2 (en) | 2006-02-16 | 2007-02-16 | Microparticulate pharmaceutical forms resistant to immediate release of the active principle in the presence of alcohol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL192773A0 true IL192773A0 (en) | 2009-02-11 |
Family
ID=37103249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL192773A IL192773A0 (en) | 2006-02-16 | 2008-07-13 | Microparticulate pharmaceutical forms resistant to immediate release of the active ingredient in the presence of alcohol |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1986616B1 (en) |
| JP (1) | JP5416974B2 (en) |
| KR (1) | KR20080099270A (en) |
| CN (1) | CN101378736B (en) |
| AU (1) | AU2007216485A1 (en) |
| BR (1) | BRPI0707859A2 (en) |
| CA (1) | CA2649265C (en) |
| ES (1) | ES2692450T3 (en) |
| FR (1) | FR2897267A1 (en) |
| IL (1) | IL192773A0 (en) |
| MX (1) | MX2008010492A (en) |
| WO (1) | WO2007093642A2 (en) |
| ZA (1) | ZA200806118B (en) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7906145B2 (en) | 2002-04-09 | 2011-03-15 | Flamel Technologies | Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| DE102005005446A1 (en) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Break-resistant dosage forms with sustained release |
| DE10361596A1 (en) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Process for producing an anti-abuse dosage form |
| DE102004032049A1 (en) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Anti-abuse, oral dosage form |
| DE102005005449A1 (en) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Process for producing an anti-abuse dosage form |
| US9023400B2 (en) | 2006-05-24 | 2015-05-05 | Flamel Technologies | Prolonged-release multimicroparticulate oral pharmaceutical form |
| FR2936709B1 (en) * | 2008-10-02 | 2012-05-11 | Ethypharm Sa | ALCOHOL-RESISTANT TABLETS. |
| JP2012508228A (en) | 2008-11-07 | 2012-04-05 | サムヤン コーポレイション | Pharmaceutical composition for controlled release of methylphenidate |
| EA019583B1 (en) * | 2008-11-18 | 2014-04-30 | Юсб Фарма, С.А. | Prolonged release formulations comprising an 2-oxo-1-pyrrolidine derivate |
| ES2602604T3 (en) * | 2008-11-18 | 2017-02-21 | Ucb Biopharma Sprl | Extended release formulations comprising a 2-oxo-1-pyrrolidine derivative |
| EP2997965B1 (en) | 2009-07-22 | 2019-01-02 | Grünenthal GmbH | Tamper-resistant dosage form for oxidation-sensitive opioids |
| EA019673B1 (en) * | 2009-10-30 | 2014-05-30 | Янссен Фармацевтика Нв | Radiolabelled pde10 ligands |
| PE20131102A1 (en) | 2010-09-02 | 2013-10-12 | Gruenenthal Chemie | HANDLING RESISTANT DOSAGE FORM INCLUDING INORGANIC SALT |
| JP6042880B2 (en) * | 2011-06-01 | 2016-12-14 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | Controlled release solid dosage form |
| AR087359A1 (en) | 2011-07-29 | 2014-03-19 | Gruenenthal Gmbh | TEST ALTERATION TABLET PROVIDING IMMEDIATE RELEASE OF THE PHARMACO |
| EA201400172A1 (en) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | SUSTAINABLE TO DESTRUCTION TABLET THAT PROVIDES IMMEDIATE RELEASE OF MEDICINES |
| CN102512415B (en) * | 2011-12-16 | 2013-07-31 | 山东齐都药业有限公司 | Clopidogrel bisulfate medicine composition and preparation method |
| AU2013248351B2 (en) | 2012-04-18 | 2018-04-26 | Grunenthal Gmbh | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
| JP5960523B2 (en) * | 2012-06-29 | 2016-08-02 | 旭化成株式会社 | Solid formulation consisting of modified starch and dissolution control agent |
| KR20160031526A (en) | 2013-07-12 | 2016-03-22 | 그뤼넨탈 게엠베하 | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
| US10195153B2 (en) | 2013-08-12 | 2019-02-05 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| BR112016010482B1 (en) | 2013-11-26 | 2022-11-16 | Grünenthal GmbH | PREPARATION OF A PHARMACEUTICAL COMPOSITION IN POWDER BY MEANS OF CRYOMING |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| AU2015254874A1 (en) * | 2014-05-01 | 2016-11-17 | Sun Pharmaceutical Industries Limited | Extended release liquid compositions of metformin |
| RU2016147009A (en) * | 2014-05-01 | 2018-06-04 | Сан Фармасьютикал Индастриз Лимитед | COMPOSITIONS WITH LONG-TERM RELEASED SUSPENSION |
| US10258583B2 (en) | 2014-05-01 | 2019-04-16 | Sun Pharmaceutical Industries Limited | Extended release liquid compositions of guanfacine |
| US9962336B2 (en) * | 2014-05-01 | 2018-05-08 | Sun Pharmaceutical Industries Limited | Extended release suspension compositions |
| US20180104197A9 (en) | 2014-05-01 | 2018-04-19 | Sun Pharmaceutical Industries Limited | Extended release liquid compositions of metformin |
| ES2809458T3 (en) | 2014-07-17 | 2021-03-04 | Pharmaceutical Manufacturing Res Services Inc | Liquid filled, abuse deterrent and immediate release dosage form |
| CA2956902A1 (en) | 2014-07-30 | 2016-02-04 | Sun Pharmaceutical Industries Limited | Dual-chamber pack |
| CA2964628A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CA2936746C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| JP2018526414A (en) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Protection against oral overdose with abuse-inhibiting immediate release formulations |
| US10238803B2 (en) | 2016-05-02 | 2019-03-26 | Sun Pharmaceutical Industries Limited | Drug delivery device for pharmaceutical compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (en) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | FORMULATIONS OF GAMMA-MODIFIED RELEASE HYDROXIBUTIRATE WITH IMPROVED PHARMACOCINETICS |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US20180369151A1 (en) | 2017-05-29 | 2018-12-27 | Grünenthal GmbH | Multiparticulate oral dosage form providing prolonged release of tapentadol |
| SG11202003439WA (en) * | 2017-11-01 | 2020-05-28 | Edgemont Pharmaceuticals Llc Trust | Alcohol-resistant oral pharmaceutical compositions of lorazepam |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| BR112021013766A2 (en) | 2019-03-01 | 2021-09-21 | Flamel Ireland Limited | GAMMA-HYDROXYBUTYRATE COMPOSITIONS WITH IMPROVED PHARMACOKINETICS IN THE FED STATE |
| GR1009751B (en) | 2019-03-22 | 2020-05-29 | "Φαρματεν Α.Β.Ε.Ε." | Prolonged-release oxalic tapentadol -containing formula and preparation method thereof |
| GR1009791B (en) | 2019-03-26 | 2020-08-03 | Φαρματεν Α.Β.Ε.Ε. | Prolonged release tapentadol-containing formula - preparation method thereof |
| CN114340614B (en) * | 2019-09-27 | 2024-01-16 | 广东东阳光药业股份有限公司 | Oseltamivir preparation |
| CN112137990A (en) * | 2020-11-04 | 2020-12-29 | 南京康川济医药科技有限公司 | Epalrestat sustained-release preparation and preparation method thereof |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| CN114965981A (en) * | 2022-03-01 | 2022-08-30 | 上海健耕医药科技股份有限公司 | Reagent R1, kit and application for the detection of valproic acid by latex-enhanced immune turbidimetry |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3784390A (en) * | 1971-07-23 | 1974-01-08 | Hayashibara Biochem Lab | Shaped bodies of pullulan and their use |
| US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US5472712A (en) * | 1991-12-24 | 1995-12-05 | Euroceltique, S.A. | Controlled-release formulations coated with aqueous dispersions of ethylcellulose |
| IL110014A (en) * | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
| ES2068762B1 (en) * | 1993-07-21 | 1995-12-01 | Lipotec Sa | A NEW PHARMACEUTICAL PREPARATION TO IMPROVE THE BIOAVAILABILITY OF DRUGS OF DIFFICULT ABSORPTION AND PROCEDURE FOR THEIR OBTAINING. |
| US5891474A (en) * | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
| US6066339A (en) * | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
| DE19809719A1 (en) * | 1998-03-06 | 1999-09-09 | Roehm Gmbh | Aqueous dispersion for binder and coating for medicine |
| KR20010041460A (en) * | 1998-04-27 | 2001-05-25 | 디르크 반테 | Pellets having a core coated with a lipid lowering agent and a polymer |
| JP3449253B2 (en) * | 1998-10-29 | 2003-09-22 | シオノギクオリカプス株式会社 | Manufacturing method of hard capsule |
| GB9828721D0 (en) * | 1998-12-24 | 1999-02-17 | Glaxo Group Ltd | Novel apparatus and process |
| US6355270B1 (en) * | 1999-01-11 | 2002-03-12 | The Regents Of The University Of California | Particles for oral delivery of peptides and proteins |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| GB9919693D0 (en) * | 1999-08-19 | 1999-10-20 | Rhone Poulenc Rorer Ltd | Process |
| GB0016002D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
| SG126676A1 (en) * | 2001-05-09 | 2007-01-30 | Nanomaterials Tech Pte Ltd | Process for the controlled production of organic particles |
| SI1414451T1 (en) * | 2001-08-06 | 2009-10-31 | Euro Celtique Sa | Opioid agonist formulations with releasable and sequestered antagonist |
| GB0125604D0 (en) * | 2001-10-25 | 2001-12-19 | Glaxo Group Ltd | Novel process |
| EP1417958A1 (en) * | 2002-11-08 | 2004-05-12 | Pari GmbH | Wet granulation process |
| WO2004056337A2 (en) * | 2002-12-18 | 2004-07-08 | Pain Therapeutics | Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats |
| FR2850576B1 (en) * | 2003-02-05 | 2007-03-23 | Ethypharm Sa | COMPOSITION COMPRISING A MIXTURE OF ACTIVE INGREDIENTS AND PROCESS FOR PREPARING THE SAME |
| DE502004011103D1 (en) * | 2003-05-02 | 2010-06-10 | Globopharm Pharmazeutische Pro | SOLID PHARMACEUTICAL PREPARATION CONTAINING LEVOTHYROXIN AND / OR LIOTHYRONIN SALTS |
| EP1479383B1 (en) * | 2003-05-20 | 2006-10-04 | Ethypharm | Oral sustained release pharmaceutical composition |
| WO2005011666A1 (en) * | 2003-08-05 | 2005-02-10 | Ranbaxy Laboratories Limited | Stable sustained release oral dosage form of gabapentin |
| US20050165038A1 (en) * | 2004-01-22 | 2005-07-28 | Maxwell Gordon | Analgetic dosage forms that are resistant to parenteral and inhalation dosing and have reduced side effects |
| EP1729741A2 (en) * | 2004-03-03 | 2006-12-13 | Spherics, Inc. | Polymeric drug delivery system for hydrophobic drugs |
| EP1721604A4 (en) * | 2004-03-04 | 2008-04-30 | Takeda Pharmaceutical | PREPARATION OF STABLE CAPSULE |
| AU2005235369B2 (en) * | 2004-04-22 | 2010-11-11 | Acucort Ab | Pharmaceutical compositions for acute glucocorticoid therapy |
| FR2872044B1 (en) * | 2004-06-28 | 2007-06-29 | Flamel Technologies Sa | PHARMACEUTICAL FORMULATION BASED ON ANTIBIOTICS IN THE MICROCAPSULAR FORM |
| WO2006038226A2 (en) * | 2004-10-08 | 2006-04-13 | Rubicon Research Pvt. Ltd. | Process for making a highly compressible controlled delivery compositions of metformin |
| FR2889810A1 (en) * | 2005-05-24 | 2007-02-23 | Flamel Technologies Sa | ORAL MEDICINAL FORM, MICROPARTICULAR, ANTI-MEASUREMENT |
| GB0506982D0 (en) * | 2005-04-06 | 2005-05-11 | Mw Encap Ltd | Abuse resistant capsules |
| FR2892937B1 (en) * | 2005-11-10 | 2013-04-05 | Flamel Tech Sa | MICROPARTICULAR ORAL PHARMACEUTICAL FORM ANTI-MEASURING |
-
2006
- 2006-02-16 FR FR0650566A patent/FR2897267A1/en not_active Withdrawn
-
2007
- 2007-02-16 CN CN200780004433.2A patent/CN101378736B/en active Active
- 2007-02-16 ES ES07712232.3T patent/ES2692450T3/en active Active
- 2007-02-16 BR BRPI0707859-5A patent/BRPI0707859A2/en not_active Application Discontinuation
- 2007-02-16 KR KR1020087020162A patent/KR20080099270A/en not_active Application Discontinuation
- 2007-02-16 AU AU2007216485A patent/AU2007216485A1/en not_active Abandoned
- 2007-02-16 WO PCT/EP2007/051528 patent/WO2007093642A2/en active Application Filing
- 2007-02-16 CA CA2649265A patent/CA2649265C/en active Active
- 2007-02-16 MX MX2008010492A patent/MX2008010492A/en not_active Application Discontinuation
- 2007-02-16 JP JP2008554786A patent/JP5416974B2/en active Active
- 2007-02-16 EP EP07712232.3A patent/EP1986616B1/en active Active
-
2008
- 2008-07-13 IL IL192773A patent/IL192773A0/en unknown
- 2008-07-15 ZA ZA200806118A patent/ZA200806118B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5416974B2 (en) | 2014-02-12 |
| EP1986616A2 (en) | 2008-11-05 |
| WO2007093642A2 (en) | 2007-08-23 |
| ZA200806118B (en) | 2009-04-29 |
| JP2009526825A (en) | 2009-07-23 |
| CN101378736B (en) | 2015-08-19 |
| CA2649265A1 (en) | 2007-08-23 |
| CN101378736A (en) | 2009-03-04 |
| AU2007216485A1 (en) | 2007-08-23 |
| CA2649265C (en) | 2019-01-29 |
| FR2897267A1 (en) | 2007-08-17 |
| BRPI0707859A2 (en) | 2011-05-10 |
| WO2007093642A3 (en) | 2007-10-04 |
| EP1986616B1 (en) | 2018-08-15 |
| MX2008010492A (en) | 2009-02-04 |
| KR20080099270A (en) | 2008-11-12 |
| ES2692450T3 (en) | 2018-12-03 |
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