IL165789A0 - Diphenyl azetidinones substituted by acidic groupsmethod for their production medicaments containin g said compounds and use thereof - Google Patents

Diphenyl azetidinones substituted by acidic groupsmethod for their production medicaments containin g said compounds and use thereof

Info

Publication number: IL165789A0
Authority: IL; Israel
Prior art keywords: groupsmethod; containin; medicaments; acidic; compounds
Prior art date: 2002-06-19

Application number

IL16578904A

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-06-19

Filing date

2004-12-15

Publication date

2006-01-15

2004-12-15 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2006-01-15 Publication of IL165789A0 publication Critical patent/IL165789A0/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Public Health (AREA)
Obesity (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL16578904A 2002-06-19 2004-12-15 Diphenyl azetidinones substituted by acidic groupsmethod for their production medicaments containin g said compounds and use thereof IL165789A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10227508A DE10227508A1 (en)	2002-06-19	2002-06-19	Acid group-substituted diphenylazetidinones, processes for their preparation, pharmaceutical compositions containing them and their use
PCT/EP2003/005816 WO2004000805A1 (en)	2002-06-19	2003-06-04	Diphenyl azetidinones substituted by acidic groups, method for their production, medicaments containing said compounds and use thereof

Publications (1)

Publication Number	Publication Date
IL165789A0 true IL165789A0 (en)	2006-01-15

Family

ID=29719283

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16578904A IL165789A0 (en)	2002-06-19	2004-12-15	Diphenyl azetidinones substituted by acidic groupsmethod for their production medicaments containin g said compounds and use thereof

Country Status (29)

Country	Link
EP (1)	EP1517891B1 (en)
JP (1)	JP2005533073A (en)
KR (1)	KR20050008835A (en)
CN (1)	CN100467448C (en)
AR (1)	AR039690A1 (en)
AU (1)	AU2003238210B2 (en)
BR (1)	BR0311896A (en)
CA (1)	CA2490112A1 (en)
DE (1)	DE10227508A1 (en)
EC (1)	ECSP045497A (en)
HK (1)	HK1079511A1 (en)
HN (1)	HN2003000185A (en)
HR (1)	HRPK20041201B3 (en)
IL (1)	IL165789A0 (en)
MA (1)	MA27206A1 (en)
MX (1)	MXPA04012093A (en)
NO (1)	NO20050134L (en)
OA (1)	OA12869A (en)
PA (1)	PA8576101A1 (en)
PE (1)	PE20040564A1 (en)
PL (1)	PL372700A1 (en)
RS (1)	RS108404A (en)
RU (1)	RU2287522C2 (en)
SV (1)	SV2004001548A (en)
TN (1)	TNSN04250A1 (en)
TW (1)	TW200413311A (en)
UA (1)	UA78577C2 (en)
UY (1)	UY27853A1 (en)
WO (1)	WO2004000805A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
JP4688819B2 (en)	2003-12-23	2011-05-25	アストラゼネカアクチボラグ	Diphenylazetidinone derivatives having cholesterol absorption inhibitory activity
JP5254620B2 (en)	2004-12-03	2013-08-07	メルク・シャープ・アンド・ドーム・コーポレーション	Substituted piperazines as CB1 antagonists
US8361999B2 (en)	2005-04-04	2013-01-29	Pontificia Universidad Catolica De Chile	Methods of treating cholesterol gallstone disease with ezetimibe
CN101243072A (en)	2005-06-20	2008-08-13	先灵公司	Piperidine derivatives useful as histamine H3 antagonists
SA06270191B1 (en)	2005-06-22	2010-03-29	استرازينيكا ايه بي	Novel 2-Azetidinone Derivatives as Cholesterol Absorption Inhibitors for the Treatment of Hyperlipidaemic Conditions
TW200811098A (en)	2006-04-27	2008-03-01	Astrazeneca Ab	Chemical compounds
EP2049472B1 (en) *	2006-06-23	2015-01-21	AbbVie Bahamas Ltd.	Cyclopropyl amine derivatives as histamin h3 receptor modulators
MX2009001043A (en)	2006-08-08	2009-02-06	Sanofi Aventis	Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use.
DE102007002260A1 (en)	2007-01-16	2008-07-31	Sanofi-Aventis	Use of substituted pyranonic acid derivatives for the preparation of medicaments for the treatment of the metabolic syndrome
EP2025674A1 (en)	2007-08-15	2009-02-18	sanofi-aventis	Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs
CN101200443B (en) *	2007-10-17	2011-06-29	中国药科大学	Azetidinone derivatives, processes for their preparation and pharmaceutical combinations containing them
DE102007054497B3 (en)	2007-11-13	2009-07-23	Sanofi-Aventis Deutschland Gmbh	New crystalline hydrate form of dodecanedioic acid 4-((2S,3R)-3-((S)-3-(4-fluoro-phenyl)-3-hydroxy-propyl)-2-(4-methoxy-phenyl)-4-oxo-azetidin-1-yl)-benzylamide ((2S,3R,4R,5R)-pentahydroxy-hexyl)-amide useful e.g. to treat hyperlipidemia
TW201014822A (en)	2008-07-09	2010-04-16	Sanofi Aventis	Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
EP2403848A1 (en)	2009-03-06	2012-01-11	Lipideon Biotechnology AG	Pharmaceutical hypocholesterolemic compositions
CN101993403B (en)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	Azetidinone compound and medical applications thereof
BR112012003973A2 (en)	2009-08-26	2015-09-08	Sanofi Sa	crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
EP2582709B1 (en)	2010-06-18	2018-01-24	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8901114B2 (en)	2011-03-08	2014-12-02	Sanofi	Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
EP2683705B1 (en)	2011-03-08	2015-04-22	Sanofi	Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8871758B2 (en)	2011-03-08	2014-10-28	Sanofi	Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120055A1 (en)	2011-03-08	2012-09-13	Sanofi	Di- and tri-substituted oxathiazine derivates, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8828995B2 (en)	2011-03-08	2014-09-09	Sanofi	Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
DE10042447A1 (en) *	2000-08-29	2002-03-28	Aventis Pharma Gmbh	Vertebrate intestinal protein that absorbs cholesterol and use of this protein to identify inhibitors of intestinal cholesterol transport
IL156552A0 (en) *	2000-12-21	2004-01-04	Aventis Pharma Gmbh	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
BR0116322A (en) *	2000-12-21	2003-10-14	Aventis Pharma Gmbh	Diphenylazetidinone derivatives, process for their preparation, medicines containing these compounds and their use
DK1345895T3 (en) *	2000-12-21	2007-05-07	Sanofi Aventis Deutschland	Hitherto diphenylazetid ions, methods for their preparation, drugs containing these compounds and their use in the treatment of lipid metabolism disorders

2002
- 2002-06-19 DE DE10227508A patent/DE10227508A1/en not_active Withdrawn
2003
- 2003-04-06 UA UAA200500488A patent/UA78577C2/en unknown
- 2003-06-02 SV SV2003001548A patent/SV2004001548A/en not_active Application Discontinuation
- 2003-06-04 RS YUP-1084/04A patent/RS108404A/en unknown
- 2003-06-04 EP EP03735535A patent/EP1517891B1/en not_active Expired - Lifetime
- 2003-06-04 CA CA002490112A patent/CA2490112A1/en not_active Abandoned
- 2003-06-04 KR KR10-2004-7020643A patent/KR20050008835A/en not_active Application Discontinuation
- 2003-06-04 BR BR0311896-7A patent/BR0311896A/en not_active IP Right Cessation
- 2003-06-04 CN CNB038143321A patent/CN100467448C/en not_active Expired - Fee Related
- 2003-06-04 OA OA1200400331A patent/OA12869A/en unknown
- 2003-06-04 RU RU2005101093/04A patent/RU2287522C2/en not_active IP Right Cessation
- 2003-06-04 WO PCT/EP2003/005816 patent/WO2004000805A1/en active Application Filing
- 2003-06-04 MX MXPA04012093A patent/MXPA04012093A/en active IP Right Grant
- 2003-06-04 PL PL03372700A patent/PL372700A1/en not_active Application Discontinuation
- 2003-06-04 AU AU2003238210A patent/AU2003238210B2/en not_active Ceased
- 2003-06-04 JP JP2004514661A patent/JP2005533073A/en not_active Abandoned
- 2003-06-16 UY UY27853A patent/UY27853A1/en unknown
- 2003-06-16 PE PE2003000596A patent/PE20040564A1/en not_active Application Discontinuation
- 2003-06-17 AR ARP030102144A patent/AR039690A1/en unknown
- 2003-06-17 HN HN2003000185A patent/HN2003000185A/en unknown
- 2003-06-17 TW TW092116321A patent/TW200413311A/en unknown
- 2003-06-18 PA PA20038576101A patent/PA8576101A1/en unknown
2004
- 2004-11-16 MA MA27954A patent/MA27206A1/en unknown
- 2004-12-15 IL IL16578904A patent/IL165789A0/en unknown
- 2004-12-16 EC EC2004005497A patent/ECSP045497A/en unknown
- 2004-12-16 TN TNP2004000250A patent/TNSN04250A1/en unknown
- 2004-12-17 HR HR20041201A patent/HRPK20041201B3/en not_active IP Right Cessation
2005
- 2005-01-11 NO NO20050134A patent/NO20050134L/en not_active Application Discontinuation
- 2005-12-12 HK HK05111396.2A patent/HK1079511A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1079511A1 (en)	2006-04-07
ECSP045497A (en)	2005-03-10
HN2003000185A (en)	2005-10-20
JP2005533073A (en)	2005-11-04
MA27206A1 (en)	2005-01-03
CN100467448C (en)	2009-03-11
RS108404A (en)	2007-02-05
NO20050134L (en)	2005-03-18
OA12869A (en)	2006-09-15
EP1517891B1 (en)	2013-04-03
WO2004000805A1 (en)	2003-12-31
BR0311896A (en)	2005-04-05
EP1517891A1 (en)	2005-03-30
CN1662495A (en)	2005-08-31
KR20050008835A (en)	2005-01-21
SV2004001548A (en)	2004-03-19
CA2490112A1 (en)	2003-12-31
RU2005101093A (en)	2005-07-20
TNSN04250A1 (en)	2007-03-12
MXPA04012093A (en)	2005-04-19
NO20050134D0 (en)	2005-01-11
AU2003238210A1 (en)	2004-01-06
PA8576101A1 (en)	2004-02-07
AR039690A1 (en)	2005-03-09
DE10227508A1 (en)	2004-01-08
HRPK20041201B3 (en)	2006-12-31
PE20040564A1 (en)	2004-10-25
HRP20041201A2 (en)	2005-08-31
PL372700A1 (en)	2005-07-25
RU2287522C2 (en)	2006-11-20
UY27853A1 (en)	2003-12-31
UA78577C2 (en)	2007-04-10
TW200413311A (en)	2004-08-01
AU2003238210B2 (en)	2008-10-23

Publication	Publication Date	Title
IL165789A0 (en)	2006-01-15	Diphenyl azetidinones substituted by acidic groupsmethod for their production medicaments containin g said compounds and use thereof
IL166058A0 (en)	2006-01-15	Novel thiophenylglycoside derivatives methods for production thereof medicaments comprising said compounds and use thereof
IL180874A0 (en)	2007-07-04	Substituted, bicyclic 8-pyrrolidinoxanthines, method for the production thereof and their use as medicaments
AU2003244650A8 (en)	2004-03-03	Medicinal compounds
GB0204719D0 (en)	2002-04-17	Medicinal compounds
GB0220730D0 (en)	2002-10-16	Medicinal compounds
GB0225030D0 (en)	2002-12-04	Medicinal compounds
HRP20041203A2 (en)	2005-06-30	Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof
HK1081965A1 (en)	2006-05-26	Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
AP1927A (en)	2008-12-10	Substituted indolepyridinium as anti-infective compounds
ZA200604432B (en)	2009-09-30	Thiozolidinones production and use thereof as medicaments
ZA200506422B (en)	2007-02-28	Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use of the same as medicaments, and medicament containing such compounds
GB0314733D0 (en)	2003-07-30	Medicaments
GB0308968D0 (en)	2003-05-28	Medicaments
GB0204392D0 (en)	2002-04-10	Pharmaceutical compound
GB0310361D0 (en)	2003-06-11	Pharmaceutical compound
ZA200803619B (en)	2009-02-25	Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for the production thereof
GB0329859D0 (en)	2004-01-28	Medicaments
GB0319379D0 (en)	2003-09-17	Medicaments
GB0315865D0 (en)	2003-08-13	Medicaments
GB0208248D0 (en)	2002-05-22	Pharmaceutical compounds
GB0230153D0 (en)	2003-02-05	Pharmaceutical compounds
AU2003229137A8 (en)	2003-12-22	Medication inhaler
SI1560826T1 (en)	2006-08-31	Pyridopyrimidinone compounds, method for production thereof and medicaments comprising the same
GB0313595D0 (en)	2003-07-16	Pharmaceutical compound