IL164247A0 - Method for preparing combretastatins - Google Patents

Method for preparing combretastatins

Info

Publication number: IL164247A0
Authority: IL; Israel
Prior art keywords: combretastatins; preparing; preparing combretastatins
Prior art date: 2002-04-11

Application number

IL16424703A

Other languages

English (en)

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-11

Filing date

2003-04-09

Publication date

2005-12-18

2003-04-09 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2005-12-18 Publication of IL164247A0 publication Critical patent/IL164247A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Detergent Compositions (AREA)
Magnetic Ceramics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)

IL16424703A 2002-04-11 2003-04-09 Method for preparing combretastatins IL164247A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0204499A FR2838437B1 (fr)	2002-04-11	2002-04-11	Procedes de preparation de combretastatines
PCT/FR2003/001117 WO2003084919A2 (fr)	2002-04-11	2003-04-09	Procedes de preparation de combretastatines

Publications (1)

Publication Number	Publication Date
IL164247A0 true IL164247A0 (en)	2005-12-18

Family

ID=28459732

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16424703A IL164247A0 (en)	2002-04-11	2003-04-09	Method for preparing combretastatins

Country Status (28)

Country	Link
EP (3)	EP1497255A2 (no)
JP (1)	JP4299677B2 (no)
KR (1)	KR101018983B1 (no)
CN (1)	CN1291970C (no)
AR (2)	AR039198A1 (no)
AU (1)	AU2003260026B2 (no)
BR (1)	BR0309087A (no)
CA (1)	CA2481742C (no)
CR (1)	CR7481A (no)
EA (1)	EA007965B1 (no)
EC (1)	ECSP045348A (no)
FR (1)	FR2838437B1 (no)
HK (1)	HK1075651A1 (no)
HR (1)	HRP20040935A2 (no)
IL (1)	IL164247A0 (no)
MA (1)	MA26407A1 (no)
ME (1)	MEP91508A (no)
MX (1)	MXPA04009112A (no)
NO (2)	NO329701B1 (no)
NZ (1)	NZ535318A (no)
OA (1)	OA12804A (no)
PL (3)	PL213967B1 (no)
RS (3)	RS52331B (no)
TN (1)	TNSN04201A1 (no)
TW (1)	TWI262179B (no)
UA (1)	UA76079C2 (no)
WO (1)	WO2003084919A2 (no)
ZA (1)	ZA200407417B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7235688B1 (en)	2004-11-04	2007-06-26	University Of Notre Dame Du Lac	Process for preparing histone deacetylase inhibitors and intermediates thereof
FR2928148B1 (fr) *	2008-02-28	2013-01-18	Sanofi Aventis	Procede de preparation de combretastatine
FR2939665B1 (fr)	2008-12-12	2011-10-07	Sanofi Aventis	Combinaison antitumorale associant l'ave8062a et le docetaxel
FR2945210B1 (fr)	2009-05-07	2011-07-01	Sanofi Aventis	Combinaison antitumorale comprenant l'ave8062 et le sorafenib
FR2953518B1 (fr) *	2009-12-03	2012-01-20	Sanofi Aventis	Procede de preparation d'un derive de combretastatine
EP2481404A1 (en)	2010-11-15	2012-08-01	Sanofi	An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
EP2397135A1 (en)	2010-06-18	2011-12-21	Sanofi	An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
WO2011158206A1 (en)	2010-06-18	2011-12-22	Sanofi	An antitumoral combination comprising ombrabulin, a taxane derivative and a platinum derivative
EP2407161A1 (en)	2010-07-13	2012-01-18	Sanofi	An antitumoral combination comprising ombrabulin and bevacizumab
FR2968557A1 (fr)	2010-12-09	2012-06-15	Sanofi Aventis	Combinaison antitumorale comprenant un derive de la famille des combretastatines et le cetuximab
FR2978662A1 (fr)	2011-08-01	2013-02-08	Sanofi Sa	Combinaison antitumorale comprenant l'ombrabuline et le cisplatine, associee a la radiotherapie
FR2978663A1 (fr)	2011-08-01	2013-02-08	Sanofi Sa	Combinaison antitumorale comprenant l'ombrabuline et le cetuximab, associee a la radiotherapie
CN103012248B (zh) *	2013-01-11	2014-11-05	浙江大德药业集团有限公司	氨基康普立停衍生物的合成及其作为口服抗肿瘤药物的应用
EP3184095A1 (en)	2013-05-23	2017-06-28	IP Gesellschaft für Management mbH	Administration units comprising polymorph 1 of 2-(2-methylamino-pyrimidin-4-yl]-1h-indole-5-carboxylic acid [(s)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide
EP4079327A1 (en)	2021-04-22	2022-10-26	Centaurus Polytherapeutics	Payloads for drug-conjugates and their use for treating cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4996237A (en)	1987-01-06	1991-02-26	Arizona Board Of Regents	Combretastatin A-4
UA19045A (uk) *	1988-02-24	1997-12-25	Ф.Хофманн - Ля Рош Аг	Спосіб одержаhhя похідhих стильбеhу
NZ232897A (en) *	1989-04-03	1992-12-23	Squibb & Sons Inc	Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
US5731353A (en) *	1993-09-08	1998-03-24	Ajinomoto Co., Inc.	Stilbene derivatives and pharmaceutical compositions containing them
TW325458B (en)	1993-09-08	1998-01-21	Ajinomoto Kk	Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer
CA2187214C (en) *	1994-04-06	2002-03-12	Hiroyoshi Hidaka	Aminostilbazole derivative and medicine
TW334418B (en) *	1995-03-07	1998-06-21	Ajinomoto Kk	Stilbene derivatives and pharmaceutical compositions
JP4551514B2 (ja) *	1999-07-23	2010-09-29	住友化学株式会社	不飽和炭化水素残基置換アニリン類の製造方法
GB9918912D0 (en)	1999-08-12	1999-10-13	Angiogene Pharm Ltd	New stilbenes with vascular damaging activity

2002
- 2002-04-11 FR FR0204499A patent/FR2838437B1/fr not_active Expired - Fee Related
2003
- 2003-03-28 AR ARP030101111A patent/AR039198A1/es active IP Right Grant
- 2003-04-09 EP EP03740582A patent/EP1497255A2/fr not_active Withdrawn
- 2003-04-09 CN CNB038075660A patent/CN1291970C/zh not_active Expired - Fee Related
- 2003-04-09 RS YU86504A patent/RS52331B/en unknown
- 2003-04-09 ME MEP-915/08A patent/MEP91508A/xx unknown
- 2003-04-09 BR BR0309087-6A patent/BR0309087A/pt not_active IP Right Cessation
- 2003-04-09 MX MXPA04009112A patent/MXPA04009112A/es active IP Right Grant
- 2003-04-09 EP EP10183123A patent/EP2348012A1/fr not_active Withdrawn
- 2003-04-09 PL PL394820A patent/PL213967B1/pl not_active IP Right Cessation
- 2003-04-09 NZ NZ535318A patent/NZ535318A/en not_active IP Right Cessation
- 2003-04-09 RS RS20110561A patent/RS20110561A3/en unknown
- 2003-04-09 KR KR1020047016132A patent/KR101018983B1/ko not_active IP Right Cessation
- 2003-04-09 WO PCT/FR2003/001117 patent/WO2003084919A2/fr active Application Filing
- 2003-04-09 OA OA1200400275A patent/OA12804A/fr unknown
- 2003-04-09 JP JP2003582118A patent/JP4299677B2/ja not_active Expired - Fee Related
- 2003-04-09 CA CA2481742A patent/CA2481742C/fr not_active Expired - Fee Related
- 2003-04-09 EP EP10183135A patent/EP2354118A1/fr not_active Withdrawn
- 2003-04-09 IL IL16424703A patent/IL164247A0/xx not_active IP Right Cessation
- 2003-04-09 RS RS20110562A patent/RS20110562A3/en unknown
- 2003-04-09 AU AU2003260026A patent/AU2003260026B2/en not_active Ceased
- 2003-04-09 PL PL371629A patent/PL213708B1/pl not_active IP Right Cessation
- 2003-04-09 EA EA200401350A patent/EA007965B1/ru not_active IP Right Cessation
- 2003-04-09 PL PL394821A patent/PL214129B1/pl not_active IP Right Cessation
- 2003-04-10 TW TW092108184A patent/TWI262179B/zh not_active IP Right Cessation
- 2003-09-04 UA UA20041109227A patent/UA76079C2/uk unknown
2004
- 2004-09-14 CR CR7481A patent/CR7481A/es unknown
- 2004-09-15 ZA ZA200407417A patent/ZA200407417B/en unknown
- 2004-09-20 MA MA27868A patent/MA26407A1/fr unknown
- 2004-10-07 HR HR20040935A patent/HRP20040935A2/hr not_active Application Discontinuation
- 2004-10-08 TN TNP2004000201A patent/TNSN04201A1/fr unknown
- 2004-10-08 EC EC2004005348A patent/ECSP045348A/es unknown
- 2004-11-05 NO NO20044814A patent/NO329701B1/no not_active IP Right Cessation
2005
- 2005-09-05 HK HK05107764A patent/HK1075651A1/xx not_active IP Right Cessation
2010
- 2010-09-01 NO NO20101215A patent/NO331372B1/no not_active IP Right Cessation
2011
- 2011-08-05 AR ARP110102854A patent/AR082581A2/es unknown

Also Published As

Publication number	Publication date
JP2005522478A (ja)	2005-07-28
CN1291970C (zh)	2006-12-27
AR082581A2 (es)	2012-12-19
MA26407A1 (fr)	2004-12-01
NO20044814L (no)	2004-01-07
ZA200407417B (en)	2006-04-26
BR0309087A (pt)	2005-02-09
EA007965B1 (ru)	2007-02-27
PL214129B1 (pl)	2013-06-28
FR2838437B1 (fr)	2004-06-04
NO331372B1 (no)	2011-12-12
RS20110561A2 (en)	2012-10-31
AR039198A1 (es)	2005-02-09
TW200401762A (en)	2004-02-01
CA2481742C (fr)	2012-06-19
AU2003260026A1 (en)	2003-10-20
PL394820A1 (pl)	2011-09-12
MXPA04009112A (es)	2004-12-07
FR2838437A1 (fr)	2003-10-17
RS20110562A2 (en)	2012-10-31
EP1497255A2 (fr)	2005-01-19
JP4299677B2 (ja)	2009-07-22
UA76079C2 (en)	2006-06-15
RS20110562A3 (en)	2013-12-31
TWI262179B (en)	2006-09-21
RS86504A (en)	2007-02-05
CN1646476A (zh)	2005-07-27
KR101018983B1 (ko)	2011-03-07
TNSN04201A1 (fr)	2007-03-12
PL213708B1 (pl)	2013-04-30
CR7481A (es)	2008-11-25
NO329701B1 (no)	2010-12-06
OA12804A (fr)	2006-07-11
WO2003084919A2 (fr)	2003-10-16
MEP91508A (en)	2011-12-20
RS52331B (en)	2012-12-31
AU2003260026B2 (en)	2008-01-03
PL394821A1 (pl)	2011-09-12
HRP20040935A2 (en)	2005-10-31
RS20110561A3 (en)	2013-10-31
PL371629A1 (en)	2005-06-27
WO2003084919A3 (fr)	2004-04-08
NO20101215L (no)	2004-01-07
EP2348012A1 (fr)	2011-07-27
KR20040108717A (ko)	2004-12-24
EP2354118A1 (fr)	2011-08-10
EA200401350A1 (ru)	2005-02-24
HK1075651A1 (en)	2005-12-23
ECSP045348A (es)	2004-11-26
PL213967B1 (pl)	2013-05-31
CA2481742A1 (fr)	2003-10-16
NZ535318A (en)	2007-02-23

Publication	Publication Date	Title
GB0208104D0 (en)	2002-05-22	Method
GB0203306D0 (en)	2002-03-27	Method
GB0211975D0 (en)	2002-07-03	Method
AU2003250196A8 (en)	2004-02-23	Method for preparing oligonucleotides
IL164247A0 (en)	2005-12-18	Method for preparing combretastatins
AU2003258070A8 (en)	2004-02-23	Electrodionization method
EP1732394A4 (en)	2011-01-05	DEHYDRATION-GRIDING PROCESS
GB0214209D0 (en)	2002-07-31	Method
GB0205509D0 (en)	2002-04-24	Method
GB0213261D0 (en)	2002-07-17	Method
GB0209296D0 (en)	2002-06-05	Method
AU2003253813A8 (en)	2004-01-23	Method for colpoplasty
AU2003222342A8 (en)	2003-09-02	Method for preparing $g(v)-bromoalkylcarboxylic compounds
EP1556396A4 (en)	2007-10-24	METHOD OF PRODUCING 2-DESOXY-L-RIBOSE
AM1402A2 (en)	2004-03-17	Hardtack preparing method
GB0208383D0 (en)	2002-05-22	Method
GB0200865D0 (en)	2002-03-06	Method
AU2002367923A8 (en)	2003-11-11	Method for preparing 2-alkoxyphenoxyethanamines from 2-alkoxyphenoxyethylacetamides
GB0207266D0 (en)	2002-05-08	Method
GB0206010D0 (en)	2002-04-24	Method
GB0208906D0 (en)	2002-05-29	Method
GB0211280D0 (en)	2002-06-26	Method
GB0202403D0 (en)	2002-03-20	Method
GB0204114D0 (en)	2002-04-10	Method
GB0215547D0 (en)	2002-08-14	Method

Legal Events

Date	Code	Title	Description
2013-04-30	KB	Patent renewed
2017-11-30	MM9K	Patent not in force due to non-payment of renewal fees