IL163827A0 - Process for synthesizing chiral n-aryl piperazines - Google Patents
Process for synthesizing chiral n-aryl piperazinesInfo
- Publication number
- IL163827A0 IL163827A0 IL16382703A IL16382703A IL163827A0 IL 163827 A0 IL163827 A0 IL 163827A0 IL 16382703 A IL16382703 A IL 16382703A IL 16382703 A IL16382703 A IL 16382703A IL 163827 A0 IL163827 A0 IL 163827A0
- Authority
- IL
- Israel
- Prior art keywords
- synthesizing chiral
- aryl piperazines
- piperazines
- aryl
- chiral
- Prior art date
Links
- 230000002194 synthesizing effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36343102P | 2002-03-12 | 2002-03-12 | |
| PCT/US2003/007078 WO2003078417A1 (en) | 2002-03-12 | 2003-03-10 | Process for synthesizing chiral n-aryl piperazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL163827A0 true IL163827A0 (en) | 2005-12-18 |
Family
ID=28041762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16382703A IL163827A0 (en) | 2002-03-12 | 2003-03-10 | Process for synthesizing chiral n-aryl piperazines |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6713626B2 (es) |
| EP (1) | EP1483255B1 (es) |
| JP (1) | JP4391241B2 (es) |
| KR (1) | KR20040105765A (es) |
| CN (2) | CN1982307A (es) |
| AR (1) | AR038930A1 (es) |
| AT (1) | ATE439356T1 (es) |
| AU (1) | AU2003220094B2 (es) |
| BR (1) | BR0308377A (es) |
| CA (1) | CA2477892C (es) |
| CR (1) | CR7431A (es) |
| DE (1) | DE60328756D1 (es) |
| EC (1) | ECSP045290A (es) |
| ES (1) | ES2329122T3 (es) |
| IL (1) | IL163827A0 (es) |
| MX (1) | MXPA04008729A (es) |
| NO (1) | NO20044050L (es) |
| NZ (1) | NZ535168A (es) |
| RU (1) | RU2315762C2 (es) |
| TW (1) | TW200403231A (es) |
| UA (1) | UA79273C2 (es) |
| WO (1) | WO2003078417A1 (es) |
| ZA (1) | ZA200408202B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060287335A1 (en) * | 2000-11-28 | 2006-12-21 | Wyeth | Serotonergic agents for treating sexual dysfunction |
| US20060223824A1 (en) * | 2000-11-28 | 2006-10-05 | Wyeth | Serotonergic agents |
| JP5080716B2 (ja) * | 2001-07-20 | 2012-11-21 | サイコジェニックス・インコーポレーテッド | 注意欠陥・多動性障害の治療 |
| WO2003078420A2 (en) * | 2002-03-12 | 2003-09-25 | Wyeth | Process for making chiral 1,4-disubstituted piperazines |
| US7361773B2 (en) * | 2002-03-12 | 2008-04-22 | Wyeth | Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
| US7091349B2 (en) * | 2002-03-12 | 2006-08-15 | Wyeth | Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution |
| AU2003220122A1 (en) * | 2002-03-12 | 2003-09-29 | Wyeth | Preparation of n1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
| US20050209245A1 (en) * | 2004-03-19 | 2005-09-22 | Wyeth | Process for preparing N-aryl-piperazine derivatives |
| US20070099931A1 (en) * | 2004-03-19 | 2007-05-03 | Wyeth | Pharmaceutical dosage forms and compositions |
| US20050215561A1 (en) * | 2004-03-19 | 2005-09-29 | Krishnendu Ghosh | Pharmaceutical dosage forms and compositions |
| TW200700413A (en) * | 2005-03-01 | 2007-01-01 | Wyeth Corp | Crystalline and amorphous 4-cyano-n-{(2r)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-propyl}-n-pyridin-2-yl-benzamide hydrochloride |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3586794T2 (de) | 1984-12-21 | 1993-05-27 | Duphar Int Res | Arzneimittel mit psychotroper wirkung. |
| JPH01125357A (ja) | 1987-11-06 | 1989-05-17 | Dainippon Pharmaceut Co Ltd | トリペプチドの誘導体 |
| IL101722A (en) * | 1991-05-02 | 1996-05-14 | Wyeth John & Brother Ltd | History of piperazine, their preparation and pharmaceutical preparations containing them |
| WO1994024115A1 (en) * | 1993-04-16 | 1994-10-27 | Santen Pharmaceutical Co., Ltd. | Novel piperazine derivative |
| WO1995033725A1 (en) | 1994-06-03 | 1995-12-14 | John Wyeth & Brother Limited | Novel processes and intermediates for the preparation of piperazine derivatives |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
| GB9413772D0 (en) * | 1994-07-08 | 1994-08-24 | Wyeth John & Brother Ltd | 5-HT1A ligands |
| GB9514901D0 (en) * | 1995-07-20 | 1995-09-20 | American Home Prod | Piperazine derivatives |
| JP2000508319A (ja) | 1996-04-10 | 2000-07-04 | メルク エンド カンパニー インコーポレーテッド | αｖβ３拮抗薬 |
| US6469007B2 (en) | 2000-11-28 | 2002-10-22 | Wyeth | Serotonergic agents |
-
2003
- 2003-03-10 AT AT03716384T patent/ATE439356T1/de not_active IP Right Cessation
- 2003-03-10 BR BR0308377-2A patent/BR0308377A/pt not_active IP Right Cessation
- 2003-03-10 KR KR10-2004-7014156A patent/KR20040105765A/ko not_active Application Discontinuation
- 2003-03-10 AU AU2003220094A patent/AU2003220094B2/en not_active Expired - Fee Related
- 2003-03-10 CN CNA2007100083292A patent/CN1982307A/zh active Pending
- 2003-03-10 TW TW092105097A patent/TW200403231A/zh unknown
- 2003-03-10 IL IL16382703A patent/IL163827A0/xx unknown
- 2003-03-10 CA CA2477892A patent/CA2477892C/en not_active Expired - Fee Related
- 2003-03-10 CN CNB038058413A patent/CN1304388C/zh not_active Expired - Fee Related
- 2003-03-10 US US10/384,845 patent/US6713626B2/en not_active Expired - Fee Related
- 2003-03-10 WO PCT/US2003/007078 patent/WO2003078417A1/en active Application Filing
- 2003-03-10 EP EP03716384A patent/EP1483255B1/en not_active Expired - Lifetime
- 2003-03-10 RU RU2004130300/04A patent/RU2315762C2/ru not_active IP Right Cessation
- 2003-03-10 JP JP2003576423A patent/JP4391241B2/ja not_active Expired - Fee Related
- 2003-03-10 MX MXPA04008729A patent/MXPA04008729A/es active IP Right Grant
- 2003-03-10 NZ NZ535168A patent/NZ535168A/xx unknown
- 2003-03-10 DE DE60328756T patent/DE60328756D1/de not_active Expired - Lifetime
- 2003-03-10 ES ES03716384T patent/ES2329122T3/es not_active Expired - Lifetime
- 2003-03-11 AR ARP030100831A patent/AR038930A1/es unknown
- 2003-10-03 UA UA20041008211A patent/UA79273C2/uk unknown
-
2004
- 2004-08-24 CR CR7431A patent/CR7431A/es not_active Application Discontinuation
- 2004-09-10 EC EC2004005290A patent/ECSP045290A/es unknown
- 2004-09-24 NO NO20044050A patent/NO20044050L/no not_active Application Discontinuation
- 2004-10-11 ZA ZA200408202A patent/ZA200408202B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0308377A (pt) | 2005-01-11 |
| RU2004130300A (ru) | 2005-04-10 |
| US6713626B2 (en) | 2004-03-30 |
| ATE439356T1 (de) | 2009-08-15 |
| TW200403231A (en) | 2004-03-01 |
| RU2315762C2 (ru) | 2008-01-27 |
| ES2329122T3 (es) | 2009-11-23 |
| NO20044050L (no) | 2004-09-24 |
| NZ535168A (en) | 2006-03-31 |
| DE60328756D1 (de) | 2009-09-24 |
| CA2477892A1 (en) | 2003-09-25 |
| MXPA04008729A (es) | 2005-07-13 |
| CR7431A (es) | 2008-07-29 |
| ZA200408202B (en) | 2007-03-28 |
| UA79273C2 (en) | 2007-06-11 |
| ECSP045290A (es) | 2004-10-26 |
| AR038930A1 (es) | 2005-02-02 |
| CN1642936A (zh) | 2005-07-20 |
| JP4391241B2 (ja) | 2009-12-24 |
| CN1982307A (zh) | 2007-06-20 |
| EP1483255B1 (en) | 2009-08-12 |
| CA2477892C (en) | 2010-11-23 |
| WO2003078417A1 (en) | 2003-09-25 |
| CN1304388C (zh) | 2007-03-14 |
| AU2003220094B2 (en) | 2009-04-23 |
| EP1483255A1 (en) | 2004-12-08 |
| US20030187265A1 (en) | 2003-10-02 |
| KR20040105765A (ko) | 2004-12-16 |
| JP2005526775A (ja) | 2005-09-08 |
| AU2003220094A1 (en) | 2003-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI348468B (en) | Process for preparing amino crotonyl compounds | |
| AU2003286588A8 (en) | Methods for synthesizing complementary dna | |
| GB0504952D0 (en) | Process for producing arylamine | |
| ZA200602149B (en) | Process for the synthesis of 6-amino-4-[(3-chloro-4-fluo-rophenyl)amino]-7-ethoxy-quinoline-3-carbonitrile | |
| IL163827A0 (en) | Process for synthesizing chiral n-aryl piperazines | |
| HK1078863A1 (en) | Process for preparing (s)-pantoprazole | |
| AU2003212892A1 (en) | Apparatus for synthesis of radiolabeled compounds | |
| SI1403264T1 (en) | Process for the industrial synthesis of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxydimethylester | |
| EP1507781A4 (en) | METHOD OF PREPARING MAYTANSINOL | |
| PL372214A1 (en) | Novel process | |
| AU2003287174A8 (en) | Process for synthesizing antifolates | |
| IL163828A0 (en) | Process for making chiral 1,4-disubstituted piperazines | |
| GB2384487B (en) | Improved process for synthesizing tackifier resin | |
| AU2003246098A8 (en) | Oxamidination process of carbonyl compounds | |
| AU2003303563A8 (en) | Process for synthesizing amine from nitrile | |
| AU2003222342A8 (en) | Method for preparing $g(v)-bromoalkylcarboxylic compounds | |
| PL375317A1 (en) | Process for producing indolopyrrolocarbazole derivative | |
| EP1546186A4 (en) | PROCESS FOR SYNTHESIS OF PEPTIDES | |
| PL1654240T3 (pl) | Sposób otrzymywania N-arylomorfolinonów | |
| PL374000A1 (en) | Improved process for hydroxyazapirones | |
| EG24122A (en) | Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines | |
| AU2003302339A8 (en) | Process for synthesizing amine from nitrile | |
| GB0229476D0 (en) | Novel process | |
| GB0206655D0 (en) | Novel process | |
| EP1498410A4 (en) | PROCESS FOR THE PREPARATION OF TERT.-LEUCIN |