IL162058A0 - Hexacyclic compounds - Google Patents

Hexacyclic compounds

Info

Publication number: IL162058A0
Authority: IL; Israel
Prior art keywords: sup; compounds; hexacyclic compounds; hexacyclic; identified
Prior art date: 2001-11-30

Application number

IL16205802A

Other languages

English (en)

Original Assignee

Chugai Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-30

Filing date

2002-11-25

Publication date

2005-11-20

2002-11-25 Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd

2005-11-20 Publication of IL162058A0 publication Critical patent/IL162058A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL16205802A 2001-11-30 2002-11-25 Hexacyclic compounds IL162058A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01128361		2001-11-30
PCT/EP2002/013216 WO2003045952A2 (en)	2001-11-30	2002-11-25	Condensed camptothecins as antitumor agents

Publications (1)

Publication Number	Publication Date
IL162058A0 true IL162058A0 (en)	2005-11-20

Family

ID=8179394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16205802A IL162058A0 (en)	2001-11-30	2002-11-25	Hexacyclic compounds

Country Status (29)

Country	Link
US (2)	US6825194B2 (es)
EP (1)	EP1480984B9 (es)
JP (1)	JP4305909B2 (es)
KR (1)	KR100895746B1 (es)
CN (1)	CN100338066C (es)
AT (1)	ATE398131T1 (es)
AU (1)	AU2002356720B2 (es)
BR (1)	BR0214615A (es)
CA (1)	CA2468824C (es)
DE (1)	DE60227113D1 (es)
ES (1)	ES2307830T3 (es)
GT (1)	GT200200250A (es)
HK (2)	HK1072935A1 (es)
HU (1)	HUP0500062A3 (es)
IL (1)	IL162058A0 (es)
MX (1)	MXPA04005185A (es)
MY (1)	MY136138A (es)
NO (1)	NO329005B1 (es)
NZ (1)	NZ533568A (es)
PA (1)	PA8558901A1 (es)
PE (1)	PE20030725A1 (es)
PL (1)	PL207510B1 (es)
RS (1)	RS51051B (es)
RU (1)	RU2299212C2 (es)
TW (1)	TWI258481B (es)
UA (1)	UA80409C2 (es)
UY (1)	UY27560A1 (es)
WO (1)	WO2003045952A2 (es)
ZA (1)	ZA200404522B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004073601A2 (en) *	2003-02-21	2004-09-02	Chugai Seiyaku Kabushiki Kaisha	Process for the preparation of hexacyclic camptothecin derivatives
BRPI0509732A (pt)	2004-04-09	2007-09-25	Chugai Pharmaceutical Co Ltd	pró-fármaco solúvel em água, composição farmacêutica, agente terapêutico, agente antifungo e uso do referido pró-fármaco
TW200744603A (en)	2005-08-22	2007-12-16	Chugai Pharmaceutical Co Ltd	Novel anticancer concomitant drug
AU2006305169A1 (en) *	2005-10-19	2007-04-26	Chugai Seiyaku Kabushiki Kaisha	Preventive or therapeutic agents for pancreatic cancer, ovarian cancer, or liver cancer comprising a novel water-soluble prodrug
US20200306243A1 (en)	2019-03-29	2020-10-01	Medimmune Limited	Compounds and conjugates thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4473692A (en)	1981-09-04	1984-09-25	Kabushiki Kaisha Yakult Honsha	Camptothecin derivatives and process for preparing same
US4939255A (en) *	1987-06-24	1990-07-03	Daiichi Pharmaceutical Co., Ltd.	Hexa-cyclic camptothecin derivatives
HU213136B (en) *	1990-08-14	1997-02-28	Kyorin Seiyaku Kk	Process for producing fluoroethyl camptothecin derivatives and pharmaceutical compositions containing them
JP3008226B2 (ja) *	1991-01-16	2000-02-14	第一製薬株式会社	六環性化合物
JP3359955B2 (ja) *	1992-07-16	2002-12-24	第一製薬株式会社	抗腫瘍剤
GB9402934D0 (en) *	1994-02-16	1994-04-06	Erba Carlo Spa	Camptothecin derivatives and process for their preparation
US5663177A (en) *	1995-05-31	1997-09-02	Smithkline Beecham Corporation	Water soluble camptothecin analogs
DE69834923T2 (de)	1997-02-14	2006-10-19	Bionumerik Pharmaceuticals, Inc., San Antonio	Hochgradig lipophile camptothecin-derivate
GB9715821D0 (en) *	1997-07-25	1997-10-01	Pharmacia & Upjohn Spa	Amidino-camptothecin derivatives

2002
- 2002-11-25 BR BR0214615-0A patent/BR0214615A/pt not_active IP Right Cessation
- 2002-11-25 WO PCT/EP2002/013216 patent/WO2003045952A2/en active IP Right Grant
- 2002-11-25 RS YUP-470/04A patent/RS51051B/sr unknown
- 2002-11-25 JP JP2003547402A patent/JP4305909B2/ja not_active Expired - Fee Related
- 2002-11-25 CA CA2468824A patent/CA2468824C/en not_active Expired - Fee Related
- 2002-11-25 KR KR1020047008223A patent/KR100895746B1/ko not_active IP Right Cessation
- 2002-11-25 RU RU2004119841/04A patent/RU2299212C2/ru not_active IP Right Cessation
- 2002-11-25 IL IL16205802A patent/IL162058A0/xx not_active IP Right Cessation
- 2002-11-25 EP EP02803790A patent/EP1480984B9/en not_active Expired - Lifetime
- 2002-11-25 NZ NZ533568A patent/NZ533568A/en not_active IP Right Cessation
- 2002-11-25 CN CNB028277465A patent/CN100338066C/zh not_active Expired - Fee Related
- 2002-11-25 AU AU2002356720A patent/AU2002356720B2/en not_active Ceased
- 2002-11-25 ES ES02803790T patent/ES2307830T3/es not_active Expired - Lifetime
- 2002-11-25 PL PL370479A patent/PL207510B1/pl not_active IP Right Cessation
- 2002-11-25 AT AT02803790T patent/ATE398131T1/de not_active IP Right Cessation
- 2002-11-25 HU HU0500062A patent/HUP0500062A3/hu unknown
- 2002-11-25 UA UA20040605013A patent/UA80409C2/uk unknown
- 2002-11-25 DE DE60227113T patent/DE60227113D1/de not_active Expired - Lifetime
- 2002-11-25 MX MXPA04005185A patent/MXPA04005185A/es active IP Right Grant
- 2002-11-26 US US10/304,672 patent/US6825194B2/en not_active Expired - Fee Related
- 2002-11-27 TW TW091134463A patent/TWI258481B/zh not_active IP Right Cessation
- 2002-11-28 MY MYPI20024479A patent/MY136138A/en unknown
- 2002-11-28 PA PA20028558901A patent/PA8558901A1/es unknown
- 2002-11-28 PE PE2002001148A patent/PE20030725A1/es not_active Application Discontinuation
- 2002-11-29 UY UY27560A patent/UY27560A1/es not_active Application Discontinuation
- 2002-11-29 GT GT200200250A patent/GT200200250A/es unknown
2004
- 2004-06-08 ZA ZA200404522A patent/ZA200404522B/en unknown
- 2004-06-29 NO NO20042729A patent/NO329005B1/no not_active IP Right Cessation
- 2004-09-16 US US10/942,044 patent/US7109195B2/en not_active Expired - Fee Related
2005
- 2005-05-30 HK HK05104506A patent/HK1072935A1/xx not_active IP Right Cessation
- 2005-10-21 HK HK05109380A patent/HK1077303A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
US6825194B2 (en)	2004-11-30
AU2002356720B2 (en)	2009-01-29
UY27560A1 (es)	2003-05-30
RU2299212C2 (ru)	2007-05-20
ATE398131T1 (de)	2008-07-15
PL207510B1 (pl)	2010-12-31
CN1617874A (zh)	2005-05-18
ZA200404522B (en)	2005-01-04
HK1077303A1 (en)	2006-02-10
HK1072935A1 (en)	2005-09-16
NZ533568A (en)	2006-01-27
NO329005B1 (no)	2010-07-19
CA2468824C (en)	2011-01-11
TW200408642A (en)	2004-06-01
JP2005511643A (ja)	2005-04-28
KR20040062976A (ko)	2004-07-09
UA80409C2 (en)	2007-09-25
PL370479A1 (en)	2005-05-30
US20030144304A1 (en)	2003-07-31
CA2468824A1 (en)	2003-06-05
RS51051B (sr)	2010-10-31
HUP0500062A2 (hu)	2005-04-28
ES2307830T3 (es)	2008-12-01
AU2002356720A1 (en)	2003-06-10
PE20030725A1 (es)	2003-08-28
NO20042729L (no)	2004-08-27
MY136138A (en)	2008-08-29
PA8558901A1 (es)	2003-06-30
CN100338066C (zh)	2007-09-19
EP1480984A2 (en)	2004-12-01
HUP0500062A3 (en)	2012-12-28
BR0214615A (pt)	2004-09-14
WO2003045952A2 (en)	2003-06-05
TWI258481B (en)	2006-07-21
KR100895746B1 (ko)	2009-04-30
GT200200250A (es)	2004-01-15
RS47004A (en)	2007-02-05
RU2004119841A (ru)	2005-03-27
WO2003045952A3 (en)	2003-10-16
EP1480984B9 (en)	2009-03-11
MXPA04005185A (es)	2004-08-11
JP4305909B2 (ja)	2009-07-29
US20050059679A1 (en)	2005-03-17
US7109195B2 (en)	2006-09-19
DE60227113D1 (de)	2008-07-24
EP1480984B1 (en)	2008-06-11

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Legal Events

Date	Code	Title
2010-11-30	FF	Patent granted
2010-11-30	KB	Patent renewed
2013-06-27	MM9K	Patent not in force due to non-payment of renewal fees