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IL154358A0 - Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists - Google Patents

Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists

Info

Publication number
IL154358A0
IL154358A0 IL15435801A IL15435801A IL154358A0 IL 154358 A0 IL154358 A0 IL 154358A0 IL 15435801 A IL15435801 A IL 15435801A IL 15435801 A IL15435801 A IL 15435801A IL 154358 A0 IL154358 A0 IL 154358A0
Authority
IL
Israel
Prior art keywords
hiv
infection
treatment
receptor antagonists
inflammatory disease
Prior art date
Application number
IL15435801A
Original Assignee
Picower Inst Med Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picower Inst Med Res filed Critical Picower Inst Med Res
Publication of IL154358A0 publication Critical patent/IL154358A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL15435801A 2000-08-10 2001-08-10 Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists IL154358A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63703300A 2000-08-10 2000-08-10
PCT/US2001/025178 WO2002013763A2 (en) 2000-08-10 2001-08-10 Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists

Publications (1)

Publication Number Publication Date
IL154358A0 true IL154358A0 (en) 2003-09-17

Family

ID=24554263

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15435801A IL154358A0 (en) 2000-08-10 2001-08-10 Treatment of hiv-1 infection and inflammatory disease using cyclophilin receptor antagonists

Country Status (6)

Country Link
EP (1) EP1309346A4 (en)
JP (1) JP2004505997A (en)
AU (1) AU2001283295A1 (en)
CA (1) CA2418303A1 (en)
IL (1) IL154358A0 (en)
WO (1) WO2002013763A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1442203A (en) * 2003-05-15 2003-09-17 陈志南 SARS crown virus and AIDS virus (HIV-1)-CD 147 acceptor target antagonist
AU2004317548A1 (en) * 2004-03-25 2005-10-06 Centocor, Inc. Use of EMMPRIN antagonists for the treatment of diseases associated with excessive angiogenesis
ATE469172T1 (en) * 2004-07-23 2010-06-15 Ge Healthcare Uk Ltd CELL CYCLE PHASE MARKERS
JP4911950B2 (en) * 2005-11-07 2012-04-04 晃 伊東 Cancer invasion / metastasis inhibitor using partial peptide of MMP-1
US8007808B2 (en) * 2008-04-04 2011-08-30 The Board Of Trustees Of The Univeristy Of Illinois Composition and method for facilitating the internalization of a therapeutic agent into a cell
CA2725534A1 (en) * 2008-05-23 2009-11-26 Uti Limited Partnership Inhibition of emmprin to treat multiple sclerosis
US8338171B2 (en) * 2009-08-31 2012-12-25 Centocor Ortho Biotech Inc. Baboon homolog of human CD147
CA2875391A1 (en) * 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
WO2016054354A1 (en) 2014-10-02 2016-04-07 Dana-Farber Cancer Institute, Inc. Compositions and methods for treating malignancies
CN111420048B (en) * 2020-03-11 2023-09-19 中国人民解放军第四军医大学 Application of anti-BASIGIN humanized antibodies in the preparation of drugs for the treatment of novel coronavirus pneumonia
CN117187190A (en) * 2023-11-07 2023-12-08 深圳湾实验室 Anti-cyclophilin A monoclonal antibody and application thereof in treatment of rheumatoid arthritis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840305A (en) * 1996-03-14 1998-11-24 The Picower Institute For Medical Research Treatment of HIV-Infection by interfering with host cell cyclophilin receptor activity
KR20010034554A (en) * 1998-03-03 2001-04-25 레이몬드, 엠. 위티 Cd147 binding molecules as therapeutics

Also Published As

Publication number Publication date
JP2004505997A (en) 2004-02-26
CA2418303A1 (en) 2002-02-21
AU2001283295A1 (en) 2002-02-25
WO2002013763A2 (en) 2002-02-21
EP1309346A2 (en) 2003-05-14
EP1309346A4 (en) 2005-06-01
WO2002013763A3 (en) 2002-08-15

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