IL149924A0 - Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases - Google Patents
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseasesInfo
- Publication number
- IL149924A0 IL149924A0 IL14992400A IL14992400A IL149924A0 IL 149924 A0 IL149924 A0 IL 149924A0 IL 14992400 A IL14992400 A IL 14992400A IL 14992400 A IL14992400 A IL 14992400A IL 149924 A0 IL149924 A0 IL 149924A0
- Authority
- IL
- Israel
- Prior art keywords
- alzheimer
- vaccine
- prevention
- treatment
- related diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16859499P | 1999-11-29 | 1999-11-29 | |
US72484200A | 2000-11-28 | 2000-11-28 | |
PCT/CA2000/001413 WO2001039796A2 (en) | 1999-11-29 | 2000-11-29 | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
IL149924A0 true IL149924A0 (en) | 2002-11-10 |
Family
ID=26864284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14992400A IL149924A0 (en) | 1999-11-29 | 2000-11-29 | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1235587A2 (en) |
JP (1) | JP2004500354A (en) |
KR (2) | KR20080059676A (en) |
CN (1) | CN1433321A (en) |
AU (1) | AU784312B2 (en) |
BR (1) | BR0016022A (en) |
CA (1) | CA2388559A1 (en) |
HK (1) | HK1049279A1 (en) |
IL (1) | IL149924A0 (en) |
MX (1) | MXPA02005576A (en) |
NO (1) | NO20022531L (en) |
NZ (1) | NZ540564A (en) |
WO (1) | WO2001039796A2 (en) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021728A1 (en) | 1995-12-12 | 1997-06-19 | Karolinska Innovations Ab | PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b) |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US6787523B1 (en) | 1997-12-02 | 2004-09-07 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US6743427B1 (en) | 1997-12-02 | 2004-06-01 | Neuralab Limited | Prevention and treatment of amyloidogenic disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
US6750324B1 (en) | 1997-12-02 | 2004-06-15 | Neuralab Limited | Humanized and chimeric N-terminal amyloid beta-antibodies |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US6761888B1 (en) | 2000-05-26 | 2004-07-13 | Neuralab Limited | Passive immunization treatment of Alzheimer's disease |
US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
US6787637B1 (en) | 1999-05-28 | 2004-09-07 | Neuralab Limited | N-Terminal amyloid-β antibodies |
UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
KR100879810B1 (en) * | 2000-02-21 | 2009-01-22 | 하. 룬드벡 아크티에셀스카브 | Novel method for down-regulation of amyloid |
EP2082749A3 (en) | 2000-07-07 | 2010-06-30 | Bioarctic Neuroscience AB | Prevention and treatment of Alzheimer's disease |
AU2007200047B2 (en) * | 2000-07-07 | 2009-11-26 | Bioarctic Neuroscience Ab | Prevention and treatment of Alzheimer's disease |
US7311893B2 (en) | 2000-07-25 | 2007-12-25 | Neurochem (International) Limited | Amyloid targeting imaging agents and uses thereof |
US20020115717A1 (en) * | 2000-07-25 | 2002-08-22 | Francine Gervais | Amyloid targeting imaging agents and uses thereof |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
MY144532A (en) | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
AR038568A1 (en) * | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | ANTI-A BETA ANTIBODIES AND ITS USE |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
JP2006511452A (en) | 2002-07-03 | 2006-04-06 | バイオ サイエンス インターナショナル インコーポレイテッド | Peptide containing aromatic D-amino acid and method of using the same |
DE10303974A1 (en) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid β (1-42) oligomers, process for their preparation and their use |
US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
TWI374893B (en) | 2003-05-30 | 2012-10-21 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
WO2004113275A2 (en) * | 2003-06-23 | 2004-12-29 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
BRPI0417689A8 (en) * | 2003-12-17 | 2017-04-25 | Elan Pharm Inc | METHOD FOR CONJUGATING A PEPTIDE IMMOGEN, COMPOSITION, CONJUGATE, IMMUNOGENIC COMPOSITION, METHOD FOR INDUCING AN IMMUNE RESPONSE IN A MAMMAL INDIVIDUAL, AND, USE OF THE CONJUGATE |
SE0401601D0 (en) | 2004-06-21 | 2004-06-21 | Bioarctic Neuroscience Ab | Protofibril specific antibodies and uses thereof |
WO2006066089A1 (en) | 2004-12-15 | 2006-06-22 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
CN101128421A (en) | 2004-12-22 | 2008-02-20 | 神经化学(国际)有限公司 | Methods and compositions for treating amyloid-related diseases |
KR100851035B1 (en) | 2005-08-23 | 2008-08-11 | 대한민국 | - - Pharmaceutical composition and composition for screening therapeutics to preventing and treating of -amyloid accumulation in brain comprising GCP-Glutamate carboxypeptidase- as an active ingredient method for screening using said composition |
EP1951750A4 (en) | 2005-11-10 | 2009-12-09 | Roskamp Res Llc | Modulation of angiogenesis by a-beta peptide fragments |
EP1954718B1 (en) | 2005-11-30 | 2014-09-03 | AbbVie Inc. | Anti-a globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
SG10201706600VA (en) | 2005-11-30 | 2017-09-28 | Abbvie Inc | Monoclonal antibodies and uses thereof |
ATE517923T1 (en) | 2005-12-12 | 2011-08-15 | Hoffmann La Roche | ANTIBODIES AGAINST AMYLOID BETA WITH GLYCOSYLATION IN THE VARIABLE REGION |
NO346055B1 (en) * | 2005-12-12 | 2022-01-24 | Ac Immune Sa | Antigen design, vaccine composition and method of manufacture thereof. |
AU2007227813B2 (en) | 2006-03-23 | 2012-09-27 | Bioarctic Neuroscience Ab | Improved protofibril selective antibodies and the use thereof |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
MX2009000476A (en) | 2006-07-14 | 2009-01-28 | Ac Immune Sa | Humanized antibody against amyloid beta. |
KR20190003862A (en) * | 2006-07-14 | 2019-01-09 | 에이씨 이뮨 에스.에이. | Humanized antibody against amyloid beta |
BRPI0719763A2 (en) * | 2006-10-02 | 2014-01-28 | Ac Immune Sa | ANTIBODY, NUCLEIC ACID MOLECULE, EXPRESSION VECTOR, CELL, COMPOSITION, MIXTURE, USE OF A CHEMICAL ANTIBODY OR A FRAGMENT OF THE SAME OR A FRAGMENT OF THE SAME AND / OR A PART OR A FUNCTION OR A PART OR A FUNCTION MIXTURE, METHODS FOR PREPARING A PHARMACEUTICAL COMPOSITION OR MIXTURE, TO PREVENT, TREAT OR RELIEVE THE EFFECTS OF A DISEASE, DIAGNOSTIC DISEASE, OR CONDITION ASSOCIATED WITH A DETERMINATION OF THE DETERMINATION OF CAROGUE DETERMINATION IN A FABRIC AND / OR BODY FLUIDS, TEST KITS FOR DISEASE AND DIAGNOSTIC TESTING AND CONDITIONS ASSOCIATED WITH AMYLOID, LIGHT CHAIN VARIABLE REGION, HEAVY CIRCLE, GENELE DESENGER, GENELE DIAGET LINES PRE-FORMED BETA-AMYLOID FIBERS TO PREVENT ABETA-INDUCED NEURON DEGRADATION, TO DIAGNOSE A PREDISPOSITION TO A DISEASE OR CO NDITION ASSOCIATED WITH AMYLOID IN A PATIENT, TO MONITOR MINIMUM RESIDUAL DISEASE IN A PATIENT, TO PROGNOSE LIABILITY OF A PATIENT WHO IS TREATED WITH AN ANTIBODY OR A COMPOSITION OF VACCINE, TO REDUCE THE CARBON LOAD TO THE CIRCLE THE NUMBER OF PLATES IN AN ANIMAL BRAIN, TO REDUCE THE TOTAL SOLUBLE OPEN QUANTITY IN AN ANIMAL BRAIN AND TO HOLD OR INCREASE COGNITIVE MEMORY CAPACITY IN A MAMMALIAN. |
PL3851447T3 (en) | 2006-10-12 | 2024-03-04 | Bellus Health Inc. | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
TR201802286T4 (en) | 2007-04-20 | 2018-03-21 | The Chemo Sero Therapeutic Res Institute | Method for enhancing the immune response with the peptide. |
JP2010528583A (en) * | 2007-06-11 | 2010-08-26 | エーシー イミューン ソシエテ アノニム | Humanized antibody against amyloid β |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
DK2182983T3 (en) | 2007-07-27 | 2014-07-14 | Janssen Alzheimer Immunotherap | TREATMENT OF AMYLOIDOGENIC DISEASES WITH HUMANIZED ANTI-ABETA ANTIBODIES |
RU2604181C2 (en) | 2007-10-05 | 2016-12-10 | Дженентек, Инк. | Using anti-amyloid beta antibody in ophthalmic diseases |
JO3076B1 (en) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | Immunotherapy regimes dependent on apoe status |
WO2009143489A2 (en) * | 2008-05-22 | 2009-11-26 | Archer Pharmaceuticals, Inc. | Modulation of angiogenesis by a-beta peptide fragments |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
EP2273273A1 (en) * | 2009-07-11 | 2011-01-12 | Rheinische Friedrich-Wilhelms-Universität Bonn | Inhibitors of the nitration of amyloid ß peptides and their uses in the diagnosis and treatment of alzheimer's disease |
JP2013523182A (en) | 2010-04-15 | 2013-06-17 | アボット・ラボラトリーズ | Amyloid beta-binding protein |
US9221900B2 (en) | 2010-07-30 | 2015-12-29 | Ac Immune S.A. | Methods for identifying safe and functional humanized antibodies |
EP2603524A1 (en) | 2010-08-14 | 2013-06-19 | AbbVie Inc. | Amyloid-beta binding proteins |
CN106661103B (en) | 2014-07-10 | 2020-11-03 | 生命北极神经科学公司 | Improved Aβ protofibril-binding antibody |
BR112017024610A2 (en) | 2015-06-24 | 2018-07-31 | F. Hoffmann-La Roche Ag | specific affinity antitransferrin receptor antibodies |
AR106189A1 (en) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | BIESPECTIFIC ANTIBODIES AGAINST HUMAN A-b AND THE HUMAN TRANSFERRINE RECEIVER AND METHODS OF USE |
NZ741067A (en) | 2015-10-02 | 2023-07-28 | Hoffmann La Roche | Bispecific anti-human cd20/human transferrin receptor antibodies and methods of use |
WO2017079835A1 (en) | 2015-11-09 | 2017-05-18 | The University Of British Columbia | Amyloid beta epitopes and antibodies thereto |
KR20180085736A (en) | 2015-11-09 | 2018-07-27 | 더 유니버시티 오브 브리티쉬 콜롬비아 | Amyloid beta mid-region epitopes and structurally selective antibodies thereto |
KR102550991B1 (en) | 2016-07-18 | 2023-07-04 | 더 유니버시티 오브 브리티쉬 콜롬비아 | Antibodies to amyloid beta |
US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998008868A1 (en) * | 1996-08-27 | 1998-03-05 | Praecis Pharmaceuticals Incorporated | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS |
NO314086B1 (en) * | 1998-05-08 | 2003-01-27 | Gemvax As | Peptides and pharmaceutical compositions containing them, nucleic acid sequences encoding such peptides, plasmids and virus vectors encompassing such DNA sequences and their use for the preparation of pharmaceutical preparations for |
CA2388092A1 (en) * | 1999-05-05 | 2000-11-16 | Neurochem, Inc. | Stereoselective antifibrillogenic peptides and peptidomimetics thereof |
-
2000
- 2000-11-29 WO PCT/CA2000/001413 patent/WO2001039796A2/en active Application Filing
- 2000-11-29 CN CN00816414A patent/CN1433321A/en active Pending
- 2000-11-29 KR KR1020087013848A patent/KR20080059676A/en not_active Application Discontinuation
- 2000-11-29 NZ NZ540564A patent/NZ540564A/en unknown
- 2000-11-29 JP JP2001541528A patent/JP2004500354A/en active Pending
- 2000-11-29 KR KR1020027006845A patent/KR20020073341A/en not_active Application Discontinuation
- 2000-11-29 AU AU18473/01A patent/AU784312B2/en not_active Ceased
- 2000-11-29 IL IL14992400A patent/IL149924A0/en unknown
- 2000-11-29 MX MXPA02005576A patent/MXPA02005576A/en not_active Application Discontinuation
- 2000-11-29 CA CA002388559A patent/CA2388559A1/en not_active Abandoned
- 2000-11-29 EP EP00981111A patent/EP1235587A2/en not_active Withdrawn
- 2000-11-29 BR BR0016022-9A patent/BR0016022A/en not_active Application Discontinuation
-
2002
- 2002-05-28 NO NO20022531A patent/NO20022531L/en not_active Application Discontinuation
-
2003
- 2003-01-16 HK HK03100407.4A patent/HK1049279A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU784312B2 (en) | 2006-03-09 |
MXPA02005576A (en) | 2002-12-13 |
CA2388559A1 (en) | 2001-06-07 |
KR20080059676A (en) | 2008-06-30 |
CN1433321A (en) | 2003-07-30 |
KR20020073341A (en) | 2002-09-23 |
NO20022531D0 (en) | 2002-05-28 |
HK1049279A1 (en) | 2003-05-09 |
NO20022531L (en) | 2002-07-12 |
EP1235587A2 (en) | 2002-09-04 |
NZ540564A (en) | 2007-04-27 |
BR0016022A (en) | 2002-08-06 |
AU1847301A (en) | 2001-06-12 |
JP2004500354A (en) | 2004-01-08 |
WO2001039796A3 (en) | 2001-12-06 |
WO2001039796A2 (en) | 2001-06-07 |
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