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IL144952A0 - Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof - Google Patents

Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Info

Publication number
IL144952A0
IL144952A0 IL14495200A IL14495200A IL144952A0 IL 144952 A0 IL144952 A0 IL 144952A0 IL 14495200 A IL14495200 A IL 14495200A IL 14495200 A IL14495200 A IL 14495200A IL 144952 A0 IL144952 A0 IL 144952A0
Authority
IL
Israel
Prior art keywords
production
methods
nucleic acids
acids encoding
chimeric polypeptides
Prior art date
Application number
IL14495200A
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP99107611A external-priority patent/EP1067194A1/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL144952A0 publication Critical patent/IL144952A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL14495200A 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof IL144952A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99107611A EP1067194A1 (en) 1999-04-16 1999-04-16 Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
EP99113967 1999-07-17
PCT/EP2000/003318 WO2000063395A1 (en) 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Publications (1)

Publication Number Publication Date
IL144952A0 true IL144952A0 (en) 2002-06-30

Family

ID=26152970

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14495200A IL144952A0 (en) 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Country Status (8)

Country Link
EP (1) EP1173589A1 (en)
JP (1) JP2003508016A (en)
AR (1) AR023482A1 (en)
AU (1) AU3966200A (en)
CA (1) CA2369820A1 (en)
IL (1) IL144952A0 (en)
NO (1) NO20015003L (en)
WO (1) WO2000063395A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60143535D1 (en) 2000-10-02 2011-01-05 Novartis Vaccines & Diagnostic HUMAN ANTIBODIES AGAINST CD40
AU2002221780A1 (en) * 2000-10-31 2002-05-15 F.Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
PT1684869E (en) 2003-11-04 2011-09-16 Novartis Vaccines & Diagnostic Methods of therapy for b cell-related cancers
AU2004287480B2 (en) 2003-11-04 2011-09-15 Novartis Vaccines And Diagnostics, Inc. Use of antagonist anti-CD40 antibodies for treatment of chronic lymphocytic leukemia
ATE474599T1 (en) 2003-11-04 2010-08-15 Novartis Vaccines & Diagnostic USE OF ANTAGONIST ANTI-CD40 MONOCLONAL ANTIBODIES FOR THE TREATMENT OF MULTIPLE MYELOMA
PT1694360E (en) 2003-11-04 2010-12-13 Novartis Vaccines & Diagnostic Use of antagonist anti-cd40 antibodies for treatment of autoimmune and inflammatory diseases and organ transplant rejection
PT1680141E (en) 2003-11-04 2010-12-20 Novartis Vaccines & Diagnostic Methods of therapy for solid tumors expressing the cd40 cell-surface antigen
CA2608750A1 (en) 2005-05-18 2006-11-23 Novartis Ag Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component
UA94264C2 (en) 2006-04-21 2011-04-26 Новартис Аг Stable liquid antagonist anti-cd40 antibody-containing pharmaceutical composition
EP2066339B1 (en) 2006-09-18 2014-08-13 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses
NZ585776A (en) 2007-10-30 2012-07-27 Univ Arkansas Compositions and methods of enhancing immune responses to flagellated bacterium
WO2009059298A2 (en) 2007-11-01 2009-05-07 Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancinc immune responses to eimeria
JP5568807B2 (en) * 2008-06-06 2014-08-13 静岡県 Identification of melanoma markers using proteomic analysis
CN102811734B (en) 2010-01-21 2016-02-10 阿肯色大学评议会 Strengthen vaccine carrier and the method for immunne response
ES2753142T3 (en) 2010-06-09 2020-04-07 Univ Arkansas Vaccine and methods to reduce a Campylobacter infection
WO2012075111A1 (en) 2010-11-30 2012-06-07 Novartis Ag Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
ES2968398T3 (en) 2013-02-14 2024-05-09 Univ Arkansas Compositions and methods for enhancing immune responses to Eimeria or limiting Eimeria infection
EP3578190A1 (en) 2013-03-15 2019-12-11 The Board of Trustees of the University of Arkansas Compositions and methods of enhancing immune responses to enteric pathogens
TWI843057B (en) 2016-05-03 2024-05-21 阿肯色州大學董事會 Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
CA3044424C (en) * 2016-11-21 2023-05-23 Nant Holdings Ip, Llc Fractal combination therapy
CA3098498A1 (en) * 2018-06-14 2019-12-19 Nantbio, Inc. Tnf-type receptor-ligand fusion proteins and methods
WO2020073045A1 (en) * 2018-10-05 2020-04-09 Nantcell, Inc. Cd40 and cd40l combo in an adenovirus vaccine vehicle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716805A (en) * 1991-10-25 1998-02-10 Immunex Corporation Methods of preparing soluble, oligomeric proteins
DE69233402T3 (en) * 1991-10-25 2009-06-25 Immunex Corp., Seattle NEW CYTOKINE
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells

Also Published As

Publication number Publication date
AR023482A1 (en) 2002-09-04
AU3966200A (en) 2000-11-02
EP1173589A1 (en) 2002-01-23
CA2369820A1 (en) 2000-10-26
WO2000063395A1 (en) 2000-10-26
NO20015003D0 (en) 2001-10-15
NO20015003L (en) 2001-10-15
JP2003508016A (en) 2003-03-04

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