IL142116A0 - Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use - Google Patents

Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use

Info

Publication number: IL142116A0
Authority: IL; Israel
Prior art keywords: molecular weight; weight markers; copolymer; copolymers; glatiramer acetate
Prior art date: 1998-09-25

Application number

IL14211699A

Other languages

English (en)

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-25

Filing date

1999-09-24

Publication date

2002-03-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22285926&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL142116(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-09-24 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2002-03-10 Publication of IL142116A0 publication Critical patent/IL142116A0/xx

Links

229920001577 copolymer Polymers 0.000 title abstract 4
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
108010072051 Glatiramer Acetate Proteins 0.000 abstract 3
FHEAIOHRHQGZPC-KIWGSFCNSA-N acetic acid;(2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound CC(O)=O.C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 FHEAIOHRHQGZPC-KIWGSFCNSA-N 0.000 abstract 3
229960003776 glatiramer acetate Drugs 0.000 abstract 3
230000004071 biological effect Effects 0.000 abstract 1
208000026278 immune system disease Diseases 0.000 abstract 1
230000014759 maintenance of location Effects 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Reproductive Health (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Emergency Medicine (AREA)
Pulmonology (AREA)

IL14211699A 1998-09-25 1999-09-24 Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use IL142116A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10169398P	1998-09-25	1998-09-25
PCT/US1999/022402 WO2000018794A1 (en)	1998-09-25	1999-09-24	Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use

Publications (1)

Publication Number	Publication Date
IL142116A0 true IL142116A0 (en)	2002-03-10

Family

ID=22285926

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
IL14211699A IL142116A0 (en)	1998-09-25	1999-09-24	Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
IL142116A IL142116A (en)	1998-09-25	2001-03-20	Copolymer 1 related polypeptides and their use as molecular weight markers
IL209189A IL209189A (en)	1998-09-25	2010-11-07	Process for Preparing Pharmaceutical Mixtures of Copolymer-Like Polypeptides-1 for Use as Molecular Weight Markers
IL209190A IL209190A (en)	1998-09-25	2010-11-07	Polypeptides with a Specific Amino Acid Sequence and a Method for Measuring Average Molecular Weight of Glutyrmer Acetate

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
IL142116A IL142116A (en)	1998-09-25	2001-03-20	Copolymer 1 related polypeptides and their use as molecular weight markers
IL209189A IL209189A (en)	1998-09-25	2010-11-07	Process for Preparing Pharmaceutical Mixtures of Copolymer-Like Polypeptides-1 for Use as Molecular Weight Markers
IL209190A IL209190A (en)	1998-09-25	2010-11-07	Polypeptides with a Specific Amino Acid Sequence and a Method for Measuring Average Molecular Weight of Glutyrmer Acetate

Country Status (17)

Country	Link
EP (3)	EP2239269B1 (xx)
JP (2)	JP4629229B2 (xx)
AT (2)	ATE431359T1 (xx)
AU (1)	AU757413B2 (xx)
CA (2)	CA2794705C (xx)
CY (3)	CY1110490T1 (xx)
DE (2)	DE69940888D1 (xx)
DK (3)	DK2090583T3 (xx)
ES (3)	ES2327301T3 (xx)
HU (3)	HU229720B1 (xx)
IL (4)	IL142116A0 (xx)
NO (2)	NO329877B1 (xx)
NZ (1)	NZ511020A (xx)
PT (3)	PT1115743E (xx)
SI (1)	SI1115743T1 (xx)
WO (1)	WO2000018794A1 (xx)
ZA (1)	ZA200102269B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1098902A4 (en)	1998-07-23	2002-07-24	Yeda Res & Dev	TREATMENT OF AUTOIMMUNE DISEASES WITH COPOLYMER 1 AND RELATED COPOLYMERS AND PEPTIDES
ES2527760T3 (es)	1998-07-23	2015-01-29	Yeda Research And Development Co., Ltd.	Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en)	1998-09-25	2004-10-05	Yeda Research And Development Co., Ltd.	Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7022663B2 (en)	2000-02-18	2006-04-04	Yeda Research And Development Co., Ltd.	Oral, nasal and pulmonary dosage formulations of copolymer 1
US20020077278A1 (en)	2000-06-05	2002-06-20	Yong V. Wee	Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
AU6887101A (en) *	2000-06-20	2002-01-02	Caprion Pharmaceuticals, Inc.	Copolymers and methods of treating prion-related diseases
WO2002076503A1 (en)	2000-06-20	2002-10-03	Mayo Foundation For Medical Education And Research	Treatment of central nervous system diseases by antibodies against glatiramer acetate
US20040037828A1 (en) *	2002-07-09	2004-02-26	Bar-Ilan University	Methods and pharmaceutical compositions for healing wounds
EP1438061B1 (en) *	2001-10-03	2016-05-11	President and Fellows of Harvard College	Copolymers for suppression of autoimmune diseases, and methods of use
SI1459065T1 (sl)	2001-12-04	2010-11-30	Teva Pharma	Postopki za merjenje potentnosti glatiramer acetata
EP1592384B1 (en)	2003-01-21	2012-10-31	Yeda Research And Development Co., Ltd.	Cop 1 for treatment of inflammatory bowel diseases
JP4668902B2 (ja)	2003-08-07	2011-04-13	ヒーラーリミテッド	創傷治癒を促進するための薬剤組成物及び方法
RU2006134701A (ru) *	2004-03-01	2008-04-10	Пептиммьюн	Способы и композиции для лечения аутоиммунных заболеваний
US7655221B2 (en)	2004-05-07	2010-02-02	Peptimmune, Inc.	Methods of treating disease with random copolymers
ES2572811T3 (es)	2004-09-09	2016-06-02	Yeda Research And Development Co., Ltd.	Mezclas de polipéptidos, composiciones que las contienen y procedimientos para obtener los mismos, y usos de los mismos
US7858337B2 (en)	2007-03-08	2010-12-28	Novartis Ag	Process for the manufacture of a composite material
US8399413B2 (en)	2009-08-20	2013-03-19	Yeda Research & Development Co., Ltd.	Low frequency glatiramer acetate therapy
USRE49251E1 (en)	2010-01-04	2022-10-18	Mapi Pharma Ltd.	Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en)	2010-03-16	2014-06-24	Teva Pharmaceutical Industries, Ltd.	Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
EP2627669B1 (en)	2010-10-11	2016-08-17	Teva Pharmaceutical Industries Ltd.	Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
CA2827275A1 (en)	2011-02-14	2012-09-20	Usv Limited	Copolymer-1, process for preparation and analytical methods thereof
HK1200274A1 (en)	2011-10-10	2015-08-07	Teva Pharmaceutical Industries Ltd.	Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate
NZ630421A (en)	2012-10-10	2018-07-27	Teva Pharma	Biomarkers predictive for clinical response for glatiramer acetate
CN104098655B (zh) *	2013-04-09	2018-01-30	深圳翰宇药业股份有限公司	用于合成醋酸格拉替雷的质谱内标的多肽
UY35790A (es)	2013-10-21	2015-05-29	Teva Pharma	Marcadores genéticos que predicen la respuesta al acetato de glatiramer
CN105218646B (zh) *	2014-06-24	2018-09-21	深圳翰宇药业股份有限公司	一种用于检测醋酸格拉替雷样本的uplc方法
US9155775B1 (en)	2015-01-28	2015-10-13	Teva Pharmaceutical Industries, Ltd.	Process for manufacturing glatiramer acetate product
US10330650B2 (en) *	2015-04-28	2019-06-25	Hybio Pharmaceutical Co., Ltd.	High performance liquid chromatography method for polypeptide mixtures
ES2744179T3 (es)	2015-09-24	2020-02-24	Chemi Spa	Análisis de la distribución de peso molecular de mezclas de polipéptidos complejas
US12097292B2 (en)	2016-08-28	2024-09-24	Mapi Pharma Ltd.	Process for preparing microparticles containing glatiramer acetate
EP3600553A4 (en)	2017-03-26	2020-09-02	Mapi Pharma Ltd.	GLATIRAMER DEPOSIT SYSTEMS FOR TREATMENT OF PROGRESSIVE FORMS OF MULTIPLE SCLEROSIS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2009996A1 (en) *	1989-02-17	1990-08-17	Kathleen S. Cook	Process for making genes encoding random polymers of amino acids
US5800808A (en)	1994-05-24	1998-09-01	Veda Research And Development Co., Ltd.	Copolymer-1 improvements in compositions of copolymers

1999
- 1999-09-24 IL IL14211699A patent/IL142116A0/xx unknown
- 1999-09-24 NZ NZ511020A patent/NZ511020A/xx not_active IP Right Cessation
- 1999-09-24 DE DE69940888T patent/DE69940888D1/de not_active Expired - Lifetime
- 1999-09-24 PT PT99949923T patent/PT1115743E/pt unknown
- 1999-09-24 PT PT09004306T patent/PT2090583E/pt unknown
- 1999-09-24 DK DK09004306.8T patent/DK2090583T3/da active
- 1999-09-24 CA CA2794705A patent/CA2794705C/en not_active Expired - Lifetime
- 1999-09-24 EP EP10171553A patent/EP2239269B1/en not_active Expired - Lifetime
- 1999-09-24 ES ES99949923T patent/ES2327301T3/es not_active Expired - Lifetime
- 1999-09-24 CA CA2343929A patent/CA2343929C/en not_active Expired - Lifetime
- 1999-09-24 HU HU1300337A patent/HU229720B1/hu unknown
- 1999-09-24 ES ES09004306T patent/ES2369642T3/es not_active Expired - Lifetime
- 1999-09-24 DK DK99949923T patent/DK1115743T3/da active
- 1999-09-24 AT AT99949923T patent/ATE431359T1/de active
- 1999-09-24 AU AU62695/99A patent/AU757413B2/en not_active Expired
- 1999-09-24 ZA ZA200102269A patent/ZA200102269B/en unknown
- 1999-09-24 AT AT09004306T patent/ATE516297T1/de active
- 1999-09-24 EP EP99949923A patent/EP1115743B1/en not_active Expired - Lifetime
- 1999-09-24 DE DE09004306T patent/DE09004306T1/de active Pending
- 1999-09-24 PT PT101715530T patent/PT2239269E/pt unknown
- 1999-09-24 HU HU1300505A patent/HU229719B1/hu unknown
- 1999-09-24 EP EP09004306A patent/EP2090583B1/en not_active Expired - Lifetime
- 1999-09-24 HU HU0103889A patent/HU229289B1/hu unknown
- 1999-09-24 JP JP2000572252A patent/JP4629229B2/ja not_active Expired - Lifetime
- 1999-09-24 DK DK10171553.0T patent/DK2239269T3/da active
- 1999-09-24 WO PCT/US1999/022402 patent/WO2000018794A1/en active IP Right Grant
- 1999-09-24 ES ES10171553T patent/ES2408706T3/es not_active Expired - Lifetime
- 1999-09-24 SI SI9931035T patent/SI1115743T1/sl unknown
2001
- 2001-03-20 IL IL142116A patent/IL142116A/en not_active IP Right Cessation
- 2001-03-21 NO NO20011441A patent/NO329877B1/no not_active IP Right Cessation
2009
- 2009-08-06 CY CY20091100835T patent/CY1110490T1/el unknown
2010
- 2010-03-25 NO NO20100442A patent/NO336685B1/no not_active IP Right Cessation
- 2010-06-23 JP JP2010142689A patent/JP4903886B2/ja not_active Expired - Lifetime
- 2010-11-07 IL IL209189A patent/IL209189A/en not_active IP Right Cessation
- 2010-11-07 IL IL209190A patent/IL209190A/en not_active IP Right Cessation
2011
- 2011-10-05 CY CY20111100947T patent/CY1112197T1/el unknown
2013
- 2013-04-15 CY CY20131100310T patent/CY1113932T1/el unknown

Also Published As

Publication number	Publication date
DK2090583T3 (da)	2011-09-12
NZ511020A (en)	2003-06-30
NO329877B1 (no)	2011-01-17
NO20100442L (no)	2001-05-25
CA2343929A1 (en)	2000-04-06
JP2010271325A (ja)	2010-12-02
EP1115743A4 (en)	2005-04-27
ES2327301T3 (es)	2009-10-27
ZA200102269B (en)	2002-03-19
HU229720B1 (en)	2014-05-28
NO20011441D0 (no)	2001-03-21
NO20011441L (no)	2001-05-25
ES2369642T3 (es)	2011-12-02
CY1110490T1 (el)	2015-04-29
IL209189A (en)	2017-11-30
EP1115743B1 (en)	2009-05-13
ATE516297T1 (de)	2011-07-15
IL209190A0 (en)	2011-01-31
ATE431359T1 (de)	2009-05-15
DK1115743T3 (da)	2009-07-27
DE09004306T1 (de)	2010-12-09
CA2794705A1 (en)	2000-04-06
HK1133021A1 (en)	2010-03-12
AU6269599A (en)	2000-04-17
HK1040521A1 (en)	2002-06-14
HU229719B1 (en)	2014-05-28
EP2239269B1 (en)	2013-01-16
DK2239269T3 (da)	2013-04-29
HUP0103889A2 (hu)	2002-03-28
CY1113932T1 (el)	2016-07-27
WO2000018794A1 (en)	2000-04-06
HUP0103889A3 (en)	2004-03-01
IL209189A0 (en)	2011-01-31
IL142116A (en)	2010-12-30
ES2408706T3 (es)	2013-06-21
HK1149279A1 (en)	2011-09-30
PT2239269E (pt)	2013-04-09
SI1115743T1 (sl)	2010-01-29
PT1115743E (pt)	2009-07-07
AU757413B2 (en)	2003-02-20
CA2343929C (en)	2013-01-29
NO336685B1 (no)	2015-10-19
DE69940888D1 (de)	2009-06-25
CA2794705C (en)	2017-07-18
PT2090583E (pt)	2011-09-14
CY1112197T1 (el)	2015-12-09
JP4629229B2 (ja)	2011-02-09
EP1115743A1 (en)	2001-07-18
EP2090583A1 (en)	2009-08-19
HU229289B1 (en)	2013-10-28
JP4903886B2 (ja)	2012-03-28
EP2239269A1 (en)	2010-10-13
IL209190A (en)	2017-11-30
EP2090583B1 (en)	2011-07-13
JP2002525378A (ja)	2002-08-13

Publication	Publication Date	Title
IL209189A0 (en)	2011-01-31	Copolymer 1 related polypeptides and their use as molecular weight markers
ATE253352T1 (de)	2003-11-15	Verwendung einer zusammensetzung enthaltend polyether block copolymere
CA2189250A1 (en)	1996-09-12	Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
DE3851251D1 (de)	1994-10-06	Rückstrahlungsgerät zur Bestimmung des Sauerstoffgehaltes.
IT8520717A0 (it)	1985-05-15	Procedimento migliorato per la polimerizzazione o copolimerizzazione del butadiene.
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IT1141249B (it)	1986-10-01	Procedimento per la preparazione di copolimeri di polisaccaridi supprotanti attivita' enzimatica,e copolimeri cosi' ottenuti
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