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IL137955A - High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents - Google Patents

High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents

Info

Publication number
IL137955A
IL137955A IL13795599A IL13795599A IL137955A IL 137955 A IL137955 A IL 137955A IL 13795599 A IL13795599 A IL 13795599A IL 13795599 A IL13795599 A IL 13795599A IL 137955 A IL137955 A IL 137955A
Authority
IL
Israel
Prior art keywords
cross
high amylose
amylose starch
linking agent
linked
Prior art date
Application number
IL13795599A
Other languages
English (en)
Hebrew (he)
Other versions
IL137955A0 (en
Original Assignee
Chouinard Francois
Matescu Mircea A
Pompilia Ispas Szabo
Vincent Lenaerts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chouinard Francois, Matescu Mircea A, Pompilia Ispas Szabo, Vincent Lenaerts filed Critical Chouinard Francois
Publication of IL137955A0 publication Critical patent/IL137955A0/xx
Publication of IL137955A publication Critical patent/IL137955A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13795599A 1998-02-24 1999-02-24 High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents IL137955A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/028,385 US6284273B1 (en) 1998-02-24 1998-02-24 Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
PCT/CA1999/000169 WO1999043305A1 (en) 1998-02-24 1999-02-24 Cross-linked high amylose starch having functional groups as a matrix for the slow release of pharmaceutical agents

Publications (2)

Publication Number Publication Date
IL137955A0 IL137955A0 (en) 2001-10-31
IL137955A true IL137955A (en) 2005-12-18

Family

ID=21843160

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13795599A IL137955A (en) 1998-02-24 1999-02-24 High cross-linked amylose with functional groups as a matrix for delayed release of pharmacological agents

Country Status (19)

Country Link
US (2) US6284273B1 (no)
EP (1) EP1059915B1 (no)
JP (1) JP2002504508A (no)
KR (1) KR100713702B1 (no)
CN (1) CN1298297A (no)
AT (1) ATE277604T1 (no)
AU (1) AU755069B2 (no)
BR (1) BR9908187A (no)
CA (1) CA2321461C (no)
CZ (1) CZ301010B6 (no)
DE (1) DE69920669T2 (no)
HU (1) HU225045B1 (no)
IL (1) IL137955A (no)
NO (1) NO329257B1 (no)
NZ (1) NZ506437A (no)
PL (1) PL192468B1 (no)
PT (1) PT1059915E (no)
TR (1) TR200003014T2 (no)
WO (1) WO1999043305A1 (no)

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CN100389752C (zh) * 1978-04-21 2008-05-28 莱博法姆公司 控释组合物
IL119660A (en) 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
DE19927688A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
US6607748B1 (en) * 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
US6777000B2 (en) 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
EP1387885A1 (en) * 2001-05-01 2004-02-11 Universite Du Quebec A Montreal Tridimensional biocompatible support structure for bioartificial organs and uses thereof
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
BR0315657A (pt) * 2002-10-25 2005-09-13 Labopharm Inc Formulação de dosagem sólida, comprimido para liberação controlada, método de fabricar uma medicação de liberação controlada, composição farmacêutica e uso de uma composição
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
CA2547843A1 (en) * 2004-02-09 2005-08-18 Transfert Plus Societe En Commandite Composition comprising polymeric material and uses thereof
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
RU2008113439A (ru) * 2005-09-09 2009-10-20 Лабофарм Инк. (CA) Композиции с замедленным высвобождением лекарственного средства
EP1926509B1 (en) * 2005-09-21 2012-01-11 SurModics, Inc. Coatings and articles including natural biodegradable polysaccharides
WO2007038126A1 (en) * 2005-09-21 2007-04-05 Surmodics, Inc. In vivo formed matrices including natural biodegradable polysaccharides and ophthalmic uses thereof
JP5122436B2 (ja) * 2006-03-14 2013-01-16 国立大学法人 奈良先端科学技術大学院大学 新規なヘパリン代替材料およびその製造方法
CA2590821A1 (en) * 2007-06-07 2008-12-07 Universite De Montreal High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same
ES2541809T3 (es) * 2007-10-16 2015-07-24 Paladin Labs Inc. Composición bicapa para la liberación sostenida de acetaminofeno y tramadol
CN101161684B (zh) * 2007-11-23 2010-05-19 华南理工大学 交联羧甲基淀粉的红外线合成方法
RU2010129907A (ru) 2007-12-17 2012-01-27 Лабофарм Инк. (CA) Лекарственная форма с контролируемым высвобождением, предотвращающая неправильное употребление
CA2709888A1 (en) * 2007-12-21 2009-07-02 Akzo Nobel N.V. Thermosetting polymers
WO2009137689A2 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
WO2010028489A1 (en) * 2008-09-15 2010-03-18 Labopharm Inc. Starch-based microparticles for the release of agents disposed therein
US8486449B2 (en) 2008-12-16 2013-07-16 Paladin Labs Inc. Misuse preventative, controlled release formulation
BR112013000190A2 (pt) 2010-07-06 2017-11-07 Gruenenthal Gmbh formas de dosagem de retenção gástrica compreendendo um análogo de gaba e um opioide
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
CA2865917C (en) * 2011-03-01 2020-09-29 4413261 Canada Inc. (Spencer Canada) Two speed monolithic system for controlled release of drugs
WO2015127537A1 (en) * 2014-02-27 2015-09-03 B-Organic Films Corp. Bioactive agents included in functionalized starch having a single helix v-structure
EP3233144A1 (en) 2014-12-19 2017-10-25 Baxter International Inc. Flowable hemostatic composition
CN104784738B (zh) * 2015-04-03 2016-12-07 四川大学 一种天然缓释多效医用海绵
CN106279453B (zh) * 2015-05-28 2019-12-10 易媛 交联的高分子化合物及其制备方法、水凝胶、水基压裂液和用途
CN105536058A (zh) * 2016-01-22 2016-05-04 青岛中腾生物技术有限公司 一种医用淀粉海绵及其制备方法和用途
GB2567493B (en) * 2017-10-13 2019-12-18 Altus Formulation Inc Starch-based release modifying excipients and pharmaceutical compositions derived therefrom
CN111072791A (zh) * 2019-12-27 2020-04-28 河南新孚望新材料科技有限公司 一种包膜剂用高直链淀粉的制备方法
KR20230165786A (ko) * 2021-03-31 2023-12-05 나가세 상교오 가부시키가이샤 수용성 폴리머의 제조 방법 및 흡수성 수지의 제조 방법
JP7125216B1 (ja) 2021-03-31 2022-08-24 長瀬産業株式会社 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法

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US4072535A (en) * 1970-12-28 1978-02-07 A. E. Staley Manufacturing Company Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules
US4369308A (en) * 1981-07-24 1983-01-18 National Starch And Chemical Corporation Low swelling starches as tablet disintegrants
JPH0791240B2 (ja) * 1987-04-01 1995-10-04 株式会社日本触媒 ２−ハロエチルアミンハロゲン化水素酸塩の製造方法
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
JPH06271704A (ja) * 1993-03-22 1994-09-27 Asahi Chem Ind Co Ltd 水性易燃性組成物
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
EP0755413A4 (en) * 1994-04-11 1999-11-17 Hoechst Celanese Corp SUPER ABSORBENT POLYMERS AND PRODUCTS MANUFACTURED WITH THEM
US5830884A (en) * 1995-01-18 1998-11-03 National Starch And Chemical Investment Holding Corporation Pharmaceutical products containing thermally-inhibited starches
US5593503A (en) * 1995-06-07 1997-01-14 National Starch And Chemical Investment Holding Corporation Process for producing amylase resistant granular starch
US5667637A (en) * 1995-11-03 1997-09-16 Weyerhaeuser Company Paper and paper-like products including water insoluble fibrous carboxyalkyl cellulose
CA2173818A1 (fr) * 1996-04-10 1997-10-11 Francois Chouinard Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
US5807575A (en) * 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds

Also Published As

Publication number Publication date
AU755069B2 (en) 2002-12-05
AU3242099A (en) 1999-09-15
NZ506437A (en) 2003-03-28
ATE277604T1 (de) 2004-10-15
CA2321461C (en) 2008-04-29
BR9908187A (pt) 2000-10-31
EP1059915B1 (en) 2004-09-29
KR20010034531A (ko) 2001-04-25
CZ20003097A3 (en) 2001-06-13
WO1999043305A1 (en) 1999-09-02
NO20004208L (no) 2000-08-23
HUP0100818A2 (hu) 2001-08-28
NO329257B1 (no) 2010-09-20
KR100713702B1 (ko) 2007-05-02
JP2002504508A (ja) 2002-02-12
HUP0100818A3 (en) 2001-12-28
CA2321461A1 (en) 1999-09-02
PT1059915E (pt) 2005-02-28
TR200003014T2 (tr) 2001-02-21
IL137955A0 (en) 2001-10-31
DE69920669T2 (de) 2005-11-03
PL342596A1 (en) 2001-06-18
CZ301010B6 (cs) 2009-10-14
PL192468B1 (pl) 2006-10-31
CN1298297A (zh) 2001-06-06
NO20004208D0 (no) 2000-08-23
DE69920669D1 (de) 2004-11-04
US6284273B1 (en) 2001-09-04
US6419957B1 (en) 2002-07-16
EP1059915A1 (en) 2000-12-20
HU225045B1 (en) 2006-05-29

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Legal Events

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FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees