IL133446A0 - Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase - Google Patents
Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferaseInfo
- Publication number
- IL133446A0 IL133446A0 IL13344698A IL13344698A IL133446A0 IL 133446 A0 IL133446 A0 IL 133446A0 IL 13344698 A IL13344698 A IL 13344698A IL 13344698 A IL13344698 A IL 13344698A IL 133446 A0 IL133446 A0 IL 133446A0
- Authority
- IL
- Israel
- Prior art keywords
- farnesyl
- protein transferase
- substituted tricyclic
- novel phenyl
- tricyclic inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87705297A | 1997-06-17 | 1997-06-17 | |
| PCT/US1998/011509 WO1998057950A1 (en) | 1997-06-17 | 1998-06-15 | Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL133446A0 true IL133446A0 (en) | 2001-04-30 |
Family
ID=25369151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13344698A IL133446A0 (en) | 1997-06-17 | 1998-06-15 | Novel phenyl-substituted tricyclic inhibitors of farnesyl-protein transferase |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0989981A1 (en) |
| JP (1) | JP2002504150A (en) |
| KR (1) | KR20010013945A (en) |
| CN (1) | CN1267292A (en) |
| AU (1) | AU8253798A (en) |
| CA (1) | CA2293549C (en) |
| HU (1) | HUP0003215A2 (en) |
| IL (1) | IL133446A0 (en) |
| NZ (1) | NZ501613A (en) |
| WO (1) | WO1998057950A1 (en) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| ATE210652T1 (en) * | 1993-10-15 | 2001-12-15 | Schering Corp | TRICYCLIC CARBAMAT DERIVATIVES FOR INHIBITING G-PROTEIN FUNCTION AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES |
| WO1995010514A1 (en) * | 1993-10-15 | 1995-04-20 | Schering Corporation | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Pharmaceutical compositions for inhibition of g-protein function and for treatment of proliferative diseases containing tricyclic compounds some such compounds and process for preparing part of them |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| CA2358394C (en) * | 1995-12-22 | 2006-05-02 | Schering Corporation | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1998
- 1998-06-15 CA CA002293549A patent/CA2293549C/en not_active Expired - Fee Related
- 1998-06-15 IL IL13344698A patent/IL133446A0/en unknown
- 1998-06-15 CN CN98808215A patent/CN1267292A/en active Pending
- 1998-06-15 WO PCT/US1998/011509 patent/WO1998057950A1/en not_active Application Discontinuation
- 1998-06-15 NZ NZ501613A patent/NZ501613A/en unknown
- 1998-06-15 AU AU82537/98A patent/AU8253798A/en not_active Abandoned
- 1998-06-15 EP EP98932719A patent/EP0989981A1/en not_active Withdrawn
- 1998-06-15 HU HU0003215A patent/HUP0003215A2/en unknown
- 1998-06-15 JP JP50450399A patent/JP2002504150A/en not_active Ceased
- 1998-06-15 KR KR1019997011970A patent/KR20010013945A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998057950A1 (en) | 1998-12-23 |
| AU8253798A (en) | 1999-01-04 |
| CA2293549A1 (en) | 1998-12-23 |
| JP2002504150A (en) | 2002-02-05 |
| CN1267292A (en) | 2000-09-20 |
| CA2293549C (en) | 2008-08-05 |
| EP0989981A1 (en) | 2000-04-05 |
| NZ501613A (en) | 2001-11-30 |
| KR20010013945A (en) | 2001-02-26 |
| HUP0003215A2 (en) | 2001-06-28 |
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