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IL131156A0 - 4-Aminoalkyl-1,3-dihydrobenzoimidazol-2-one derivatives their preparation and their use as dopamine autoreceptor (d2) agonists - Google Patents

4-Aminoalkyl-1,3-dihydrobenzoimidazol-2-one derivatives their preparation and their use as dopamine autoreceptor (d2) agonists

Info

Publication number
IL131156A0
IL131156A0 IL13115698A IL13115698A IL131156A0 IL 131156 A0 IL131156 A0 IL 131156A0 IL 13115698 A IL13115698 A IL 13115698A IL 13115698 A IL13115698 A IL 13115698A IL 131156 A0 IL131156 A0 IL 131156A0
Authority
IL
Israel
Prior art keywords
dihydrobenzoimidazol
aminoalkyl
agonists
derivatives
preparation
Prior art date
Application number
IL13115698A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL131156A0 publication Critical patent/IL131156A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL13115698A 1997-02-18 1998-01-13 4-Aminoalkyl-1,3-dihydrobenzoimidazol-2-one derivatives their preparation and their use as dopamine autoreceptor (d2) agonists IL131156A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80187097A 1997-02-18 1997-02-18
PCT/US1998/000623 WO1998035946A1 (en) 1997-02-18 1998-01-13 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists

Publications (1)

Publication Number Publication Date
IL131156A0 true IL131156A0 (en) 2001-01-28

Family

ID=25182225

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13115698A IL131156A0 (en) 1997-02-18 1998-01-13 4-Aminoalkyl-1,3-dihydrobenzoimidazol-2-one derivatives their preparation and their use as dopamine autoreceptor (d2) agonists

Country Status (14)

Country Link
EP (1) EP0964853A1 (zh)
JP (1) JP2001511804A (zh)
KR (1) KR20000071160A (zh)
CN (1) CN1138761C (zh)
AR (1) AR011138A1 (zh)
AU (1) AU744443B2 (zh)
BR (1) BR9807703A (zh)
CA (1) CA2278747A1 (zh)
HU (1) HUP0001262A3 (zh)
IL (1) IL131156A0 (zh)
NZ (1) NZ337271A (zh)
TW (1) TW383303B (zh)
WO (1) WO1998035946A1 (zh)
ZA (1) ZA981310B (zh)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
ATE210657T1 (de) * 1994-10-14 2001-12-15 Merck Patent Gmbh Zns wirksames (r)-(-)-2-(5-(4-fluorophenyl)-3- pyridylmethylaminomethyl)chroman
AR004523A1 (es) * 1995-11-06 1998-12-16 American Home Prod 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
ATE227284T1 (de) * 1996-08-27 2002-11-15 Wyeth Corp 4-aminoethoxy-indolonderivate als dopamin d2 agonisten
KR20000035818A (ko) * 1996-08-27 2000-06-26 이곤 이 버그 4-아미노에톡시 인돌론 유도체

Also Published As

Publication number Publication date
ZA981310B (en) 1999-08-17
CN1252060A (zh) 2000-05-03
WO1998035946A1 (en) 1998-08-20
HUP0001262A2 (hu) 2001-04-28
AU6023498A (en) 1998-09-08
EP0964853A1 (en) 1999-12-22
JP2001511804A (ja) 2001-08-14
AR011138A1 (es) 2000-08-02
HUP0001262A3 (en) 2002-04-29
CN1138761C (zh) 2004-02-18
AU744443B2 (en) 2002-02-21
TW383303B (en) 2000-03-01
CA2278747A1 (en) 1998-08-20
BR9807703A (pt) 2000-05-02
KR20000071160A (ko) 2000-11-25
NZ337271A (en) 2001-01-26

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