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IL130856A - Proxtin preparations in spray-dry condition and their preparation - Google Patents

Proxtin preparations in spray-dry condition and their preparation

Info

Publication number
IL130856A
IL130856A IL13085698A IL13085698A IL130856A IL 130856 A IL130856 A IL 130856A IL 13085698 A IL13085698 A IL 13085698A IL 13085698 A IL13085698 A IL 13085698A IL 130856 A IL130856 A IL 130856A
Authority
IL
Israel
Prior art keywords
paroxetine hydrochloride
spray
dried
process according
paroxetine
Prior art date
Application number
IL13085698A
Other languages
English (en)
Hebrew (he)
Other versions
IL130856A0 (en
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700692.8A external-priority patent/GB9700692D0/en
Priority claimed from GBGB9714873.8A external-priority patent/GB9714873D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL130856A0 publication Critical patent/IL130856A0/xx
Publication of IL130856A publication Critical patent/IL130856A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL13085698A 1997-01-15 1998-01-12 Proxtin preparations in spray-dry condition and their preparation IL130856A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9700692.8A GB9700692D0 (en) 1997-01-15 1997-01-15 Novel process and compound
GBGB9714873.8A GB9714873D0 (en) 1997-07-15 1997-07-15 Novel process and compound
PCT/GB1998/000081 WO1998031365A1 (en) 1997-01-15 1998-01-12 Paroxetine compositions

Publications (2)

Publication Number Publication Date
IL130856A0 IL130856A0 (en) 2001-01-28
IL130856A true IL130856A (en) 2001-09-13

Family

ID=26310796

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13085698A IL130856A (en) 1997-01-15 1998-01-12 Proxtin preparations in spray-dry condition and their preparation

Country Status (21)

Country Link
US (1) US20010049442A1 (id)
EP (1) EP0952831A1 (id)
JP (1) JP2001508460A (id)
KR (1) KR20000070151A (id)
CN (1) CN1249686A (id)
AP (1) AP9901604A0 (id)
AU (1) AU730532B2 (id)
BG (1) BG103648A (id)
BR (1) BR9806754A (id)
CA (1) CA2277480A1 (id)
EA (1) EA002034B1 (id)
HU (1) HUP0000960A3 (id)
ID (1) ID23250A (id)
IL (1) IL130856A (id)
NO (1) NO993460L (id)
NZ (1) NZ336587A (id)
OA (1) OA11077A (id)
PL (1) PL334568A1 (id)
SK (1) SK95099A3 (id)
TR (1) TR199901622T2 (id)
WO (1) WO1998031365A1 (id)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9724544D0 (en) * 1997-11-21 1998-01-21 Smithkline Beecham Plc Novel Formulation
US6168805B1 (en) * 1998-05-07 2001-01-02 Endo Pharmaceuticals, Inc. Aqueous process for manufacturing paroxetine solid dispersions
GB9810181D0 (en) * 1998-05-13 1998-07-08 Smithkline Beecham Plc Novel formulations
AU5428999A (en) * 1998-08-07 2000-02-28 Smithkline Beecham Plc Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
EP1161241B1 (de) 1999-03-12 2005-12-07 Aesica Pharmaceuticals Ltd. Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
GB9914600D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel,process
ES2162560B1 (es) * 1999-06-25 2002-07-16 Rodriguez Concepcion Pena Uso de fluoxetina, paroxetina y otros isrs para la fabricacion de medicamentos con el fin de aumentar la capacidad de abstenerse de substancias o actividades que crean dependencia.
ATE248165T1 (de) 1999-07-01 2003-09-15 Italfarmaco Spa Komplexe von paroxetin mit cyclodextrin oder cyclodextrin derivaten
GB9919052D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel compound composition and process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
US6660298B1 (en) * 2000-07-27 2003-12-09 Pentech Pharmaceuticals, Inc. Paroxetine tablets and capsules
NZ523902A (en) * 2000-08-28 2004-05-28 Synthon Bv Paroxetine compositions and processes for making the same
WO2006023347A1 (en) * 2004-08-20 2006-03-02 Alpharma, Inc. Paroxetine formulations
CN104027306A (zh) * 2014-06-25 2014-09-10 万特制药(海南)有限公司 帕罗西汀口服混悬液及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2297550B (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
CA2206592A1 (en) * 1996-05-30 1997-11-30 Shu-Zhong Wang Method of producing amorphous paroxetine hydrochloride

Also Published As

Publication number Publication date
HUP0000960A2 (hu) 2001-02-28
BG103648A (en) 2000-04-28
KR20000070151A (ko) 2000-11-25
EP0952831A1 (en) 1999-11-03
AU730532B2 (en) 2001-03-08
JP2001508460A (ja) 2001-06-26
OA11077A (en) 2003-03-13
AP9901604A0 (en) 1999-09-30
BR9806754A (pt) 2000-03-14
CA2277480A1 (en) 1998-07-23
WO1998031365A1 (en) 1998-07-23
EA199900655A1 (ru) 2000-02-28
ID23250A (id) 2000-03-30
PL334568A1 (en) 2000-03-13
EA002034B1 (ru) 2001-12-24
US20010049442A1 (en) 2001-12-06
NZ336587A (en) 2001-01-26
NO993460D0 (no) 1999-07-14
TR199901622T2 (xx) 1999-09-21
HUP0000960A3 (en) 2001-04-28
IL130856A0 (en) 2001-01-28
NO993460L (no) 1999-09-14
CN1249686A (zh) 2000-04-05
SK95099A3 (en) 2000-01-18
AU5567398A (en) 1998-08-07

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