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IL115156A - Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines - Google Patents

Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines

Info

Publication number
IL115156A
IL115156A IL11515695A IL11515695A IL115156A IL 115156 A IL115156 A IL 115156A IL 11515695 A IL11515695 A IL 11515695A IL 11515695 A IL11515695 A IL 11515695A IL 115156 A IL115156 A IL 115156A
Authority
IL
Israel
Prior art keywords
cytosines
dioxolan
hydroxymethyl
cancer
treatment
Prior art date
Application number
IL11515695A
Other languages
English (en)
Other versions
IL115156A0 (en
Original Assignee
Univ Georgia
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/301,298 external-priority patent/US5817667A/en
Application filed by Univ Georgia, Univ Yale filed Critical Univ Georgia
Publication of IL115156A0 publication Critical patent/IL115156A0/xx
Publication of IL115156A publication Critical patent/IL115156A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL11515695A 1994-09-06 1995-09-04 Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines IL115156A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/301,298 US5817667A (en) 1991-04-17 1994-09-06 Compounds and methods for the treatment of cancer
US39063395A 1995-02-17 1995-02-17

Publications (2)

Publication Number Publication Date
IL115156A0 IL115156A0 (en) 1995-12-31
IL115156A true IL115156A (en) 2000-07-16

Family

ID=26972285

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11515695A IL115156A (en) 1994-09-06 1995-09-04 Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines

Country Status (31)

Country Link
US (3) US6063787A (pl)
EP (2) EP0781136B1 (pl)
JP (1) JP3979662B2 (pl)
KR (1) KR100374477B1 (pl)
CN (3) CN1111409C (pl)
AP (1) AP783A (pl)
AT (1) ATE267015T1 (pl)
AU (1) AU704977B2 (pl)
BG (1) BG63122B1 (pl)
BR (1) BR9508886A (pl)
CA (1) CA2199117C (pl)
CZ (1) CZ297873B6 (pl)
DE (1) DE69533066T2 (pl)
DK (1) DK0781136T3 (pl)
ES (1) ES2219666T3 (pl)
FI (1) FI970918A (pl)
HU (1) HUT77172A (pl)
IL (1) IL115156A (pl)
IS (1) IS2011B (pl)
MY (1) MY121548A (pl)
NO (1) NO313268B1 (pl)
NZ (1) NZ335013A (pl)
OA (1) OA10473A (pl)
PL (2) PL189288B1 (pl)
PT (1) PT781136E (pl)
RO (1) RO118748B1 (pl)
RU (1) RU2168995C2 (pl)
SI (1) SI0781136T1 (pl)
SK (1) SK284564B6 (pl)
WO (1) WO1996007413A1 (pl)
ZA (1) ZA957483B (pl)

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CN1565031B (zh) 2002-06-28 2010-09-29 Lg电子株式会社 一种用于管理多个路径数据的记录和再现的方法及装置
KR100665439B1 (ko) 2002-10-14 2007-01-04 엘지전자 주식회사 기록된 복수의 오디오 스트림의 재생을 관리하기 위한데이터 구조를 갖는 기록 매체, 그에 따른 기록 및 재생방법 및 장치
JP4903998B2 (ja) 2002-10-15 2012-03-28 エルジー エレクトロニクス インコーポレイティド 記録された複数のグラフィックストリームの再生を管理するためのデータ構造を有する記録媒体、それによる記録及び再生方法及び装置
US7720356B2 (en) 2002-11-12 2010-05-18 Lg Electronics Inc Recording medium having data structure for managing reproduction of multiple reproduction path video data recorded thereon and recording and reproducing methods and apparatuses
US7664372B2 (en) 2002-11-20 2010-02-16 Lg Electronics Inc. Recording medium having data structure for managing reproduction of multiple component data recorded thereon and recording and reproducing methods and apparatuses
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KR101119108B1 (ko) 2003-02-28 2012-06-12 엘지전자 주식회사 기록되는 비디오 데이터의 랜덤/셔플 재생을 관리하기 위한데이터 구조를 갖는 기록 매체와 그에 따른 기록 및 재생방법 및 장치
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CN103720693A (zh) * 2011-11-15 2014-04-16 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
CN102406649A (zh) * 2011-11-15 2012-04-11 张始状 人体五种正常碱基在制备治疗肿瘤药物中的应用
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Also Published As

Publication number Publication date
DE69533066T2 (de) 2005-06-02
US6063787A (en) 2000-05-16
US20080171758A1 (en) 2008-07-17
WO1996007413A1 (en) 1996-03-14
RU2168995C2 (ru) 2001-06-20
CA2199117A1 (en) 1996-03-14
NO971015L (no) 1997-03-05
CA2199117C (en) 2006-04-11
AU704977B2 (en) 1999-05-13
NO313268B1 (no) 2002-09-09
IL115156A0 (en) 1995-12-31
NO971015D0 (no) 1997-03-05
JPH10506385A (ja) 1998-06-23
FI970918A (fi) 1997-05-02
AP783A (en) 1999-11-17
MY121548A (en) 2006-02-28
KR970705393A (ko) 1997-10-09
SK284564B6 (sk) 2005-06-02
IS2011B (is) 2005-05-13
CZ63397A3 (en) 1997-07-16
BG63122B1 (en) 2001-04-30
ES2219666T3 (es) 2004-12-01
EP1468687A1 (en) 2004-10-20
EP0781136B1 (en) 2004-05-19
IS4434A (is) 1997-03-04
CN1251680C (zh) 2006-04-19
KR100374477B1 (ko) 2003-06-19
HUT77172A (hu) 1998-03-02
US8076347B2 (en) 2011-12-13
SI0781136T1 (en) 2004-08-31
FI970918A0 (fi) 1997-03-04
AU3586295A (en) 1996-03-27
EP0781136A1 (en) 1997-07-02
PL318971A1 (en) 1997-07-21
US20050261320A1 (en) 2005-11-24
OA10473A (en) 2002-04-08
ATE267015T1 (de) 2004-06-15
JP3979662B2 (ja) 2007-09-19
PL188359B1 (pl) 2005-01-31
CN1827108A (zh) 2006-09-06
CN1448142A (zh) 2003-10-15
EP0781136A4 (en) 1999-06-23
BG101284A (en) 1998-03-31
CN1111409C (zh) 2003-06-18
US7262213B2 (en) 2007-08-28
NZ335013A (en) 2000-07-28
AP9700939A0 (en) 1997-04-30
RO118748B1 (ro) 2003-10-30
DE69533066D1 (de) 2004-06-24
CZ297873B6 (cs) 2007-04-18
ZA957483B (en) 1997-06-06
DK0781136T3 (da) 2004-08-02
CN1160351A (zh) 1997-09-24
PT781136E (pt) 2004-09-30
SK28197A3 (en) 1997-09-10
BR9508886A (pt) 1997-12-30
PL189288B1 (pl) 2005-07-29

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