IL106408A0 - Benzimidazoles,their preparation and pharmaceutical compositions containing them - Google Patents

Benzimidazoles,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL106408A0
Authority: IL; Israel
Prior art keywords: benzimidazoles; preparation; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1992-07-22

Application number

IL106408A

Other versions

IL106408A (en

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-22

Filing date

1993-07-20

Publication date

1993-11-15

1993-07-20 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1993-11-15 Publication of IL106408A0 publication Critical patent/IL106408A0/en

1998-08-16 Publication of IL106408A publication Critical patent/IL106408A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL10640893A 1992-07-22 1993-07-20 Biphenylmethyl-1-benzimidazole derivatives their preparation and pharmaceutical compositions containing them IL106408A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4224133A DE4224133A1 (en)	1992-07-22	1992-07-22	Benzimidazoles, medicaments containing these compounds and process for their preparation

Publications (2)

Publication Number	Publication Date
IL106408A0 true IL106408A0 (en)	1993-11-15
IL106408A IL106408A (en)	1998-08-16

Family

ID=6463804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL10640893A IL106408A (en)	1992-07-22	1993-07-20	Biphenylmethyl-1-benzimidazole derivatives their preparation and pharmaceutical compositions containing them

Country Status (20)

Country	Link
EP (1)	EP0581166A1 (en)
JP (1)	JPH06179659A (en)
KR (1)	KR940005584A (en)
CN (1)	CN1050122C (en)
AU (1)	AU675433B2 (en)
CA (1)	CA2100927A1 (en)
CZ (1)	CZ144993A3 (en)
DE (1)	DE4224133A1 (en)
FI (1)	FI933284A (en)
HU (1)	HUT64955A (en)
IL (1)	IL106408A (en)
MX (1)	MX9304424A (en)
NO (1)	NO300772B1 (en)
NZ (1)	NZ248217A (en)
PL (1)	PL172929B1 (en)
RU (1)	RU2126401C1 (en)
SG (1)	SG43083A1 (en)
SK (1)	SK73293A3 (en)
TW (1)	TW229207B (en)
ZA (1)	ZA93529B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4233590A1 (en) *	1992-10-06	1994-04-07	Thomae Gmbh Dr K	Benzimidazoles, medicaments containing these compounds and process for their preparation
DE4304455A1 (en) *	1993-02-15	1994-08-18	Bayer Ag	Heterocyclic substituted phenyl-cyclohexane-carboxylic acid derivatives
DE4324580A1 (en) *	1993-07-22	1995-01-26	Thomae Gmbh Dr K	Bicyclic heterocycles, pharmaceutical compositions containing them and methods for their preparation
JP3063162B2 (en) *	1995-12-28	2000-07-12	藤沢薬品工業株式会社	Benzimidazole derivatives
TW453999B (en) *	1997-06-27	2001-09-11	Fujisawa Pharmaceutical Co	Benzimidazole derivatives
HU222773B1 (en) *	2000-04-21	2003-10-28	Richter Gedeon Vegyészeti Gyár Rt.	Process for producing a known tetrazole derivative
JPWO2005011736A1 (en) *	2003-07-30	2006-09-14	株式会社東北テクノアーチ	Preventive and / or therapeutic agent for Alzheimer's disease
CN101921265B (en) *	2009-11-25	2012-07-04	北京理工大学	Biphenylacylamine tetrazole compounds, synthetic method and application
CN101891735B (en) *	2009-11-25	2012-07-18	北京理工大学	Biphenyl sulfafurazole compound, synthesis method and application thereof
BR112014010391A2 (en) *	2011-11-03	2017-04-18	Hoffmann La Roche	compound, pharmaceutical composition, process of producing a pharmaceutical composition, method of treatment, kit and use of a pharmaceutical composition
CN105820125B (en) *	2015-01-09	2018-12-07	北京中医药大学	A kind of compound and its preparation method and application for treating hypertension
CN105384729B (en) *	2015-07-09	2019-02-19	天津青松华药医药有限公司	Telmisartan ester derivative and the preparation method and application thereof
CN106749220B (en) *	2017-01-18	2019-08-06	东华大学	A kind of 6'-substituted benzimidazole-4-substituted methyl indole derivative and its preparation and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3928177A1 (en) *	1989-04-08	1991-02-28	Thomae Gmbh Dr K	BENZIMIDAZOLE, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
RU1836357C (en) *	1990-07-23	1993-08-23	Др.Карл Томэ ГмбХ	Benzimidazole derivatives, their isomers, mixtures of isomers, hydrates or their physiologically bearable salts possessing properties antagonistic to angiotenzine
SI9210098B (en) *	1991-02-06	2000-06-30	Dr. Karl Thomae	Benzimidazoles, drugs with this compounds, and process for their preparation
DE4237656A1 (en) *	1992-06-13	1993-12-16	Merck Patent Gmbh	benzimidazole derivatives

1992
- 1992-07-22 DE DE4224133A patent/DE4224133A1/en not_active Withdrawn
1993
- 1993-06-12 TW TW082104675A patent/TW229207B/zh active
- 1993-07-12 SK SK732-93A patent/SK73293A3/en unknown
- 1993-07-20 SG SG1996003403A patent/SG43083A1/en unknown
- 1993-07-20 EP EP93111581A patent/EP0581166A1/en not_active Ceased
- 1993-07-20 CZ CZ931449A patent/CZ144993A3/en unknown
- 1993-07-20 CN CN93108085A patent/CN1050122C/en not_active Expired - Fee Related
- 1993-07-20 IL IL10640893A patent/IL106408A/en not_active IP Right Cessation
- 1993-07-20 CA CA002100927A patent/CA2100927A1/en not_active Abandoned
- 1993-07-21 ZA ZA93529A patent/ZA93529B/en unknown
- 1993-07-21 AU AU42094/93A patent/AU675433B2/en not_active Expired
- 1993-07-21 FI FI933284A patent/FI933284A/en unknown
- 1993-07-21 NZ NZ248217A patent/NZ248217A/en unknown
- 1993-07-21 HU HU9302115A patent/HUT64955A/en unknown
- 1993-07-21 JP JP5179485A patent/JPH06179659A/en active Pending
- 1993-07-21 PL PL93299754A patent/PL172929B1/en unknown
- 1993-07-21 NO NO932636A patent/NO300772B1/en not_active IP Right Cessation
- 1993-07-21 KR KR1019930013764A patent/KR940005584A/en not_active Application Discontinuation
- 1993-07-22 RU RU93049407A patent/RU2126401C1/en active
- 1993-07-22 MX MX9304424A patent/MX9304424A/en unknown

Also Published As

Publication number	Publication date
NO932636L (en)	1994-01-24
HU9302115D0 (en)	1993-10-28
PL172929B1 (en)	1997-12-31
KR940005584A (en)	1994-03-21
SK73293A3 (en)	1994-04-06
FI933284A (en)	1994-01-23
FI933284A0 (en)	1993-07-21
CN1050122C (en)	2000-03-08
DE4224133A1 (en)	1994-01-27
NO300772B1 (en)	1997-07-21
EP0581166A1 (en)	1994-02-02
MX9304424A (en)	1994-01-31
AU675433B2 (en)	1997-02-06
JPH06179659A (en)	1994-06-28
AU4209493A (en)	1994-01-27
IL106408A (en)	1998-08-16
SG43083A1 (en)	1997-10-17
NO932636D0 (en)	1993-07-21
PL299754A1 (en)	1994-03-21
NZ248217A (en)	1996-06-25
TW229207B (en)	1994-09-01
CZ144993A3 (en)	1994-03-16
CA2100927A1 (en)	1994-01-23
ZA93529B (en)	1995-01-23
CN1083812A (en)	1994-03-16
RU2126401C1 (en)	1999-02-20
HUT64955A (en)	1994-03-28

Publication	Publication Date	Title
IL104703A0 (en)	1993-06-10	Benzimidazolyl derivatives,their preparation and pharmaceutical compositions containing them
IL101864A0 (en)	1992-12-30	Thiopyranopyrrole derivatives,their preparation and pharmaceutical compositions containing them
IL106141A0 (en)	1993-10-20	Thiazolylvinylphenyl derivatives,their manufacture and pharmaceutical compositions containing them
IL99225A0 (en)	1992-07-15	3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL106353A0 (en)	1993-11-15	Unsymmetrical mono-3-nitro-bis-naphthalimides,their preparation and pharmaceutical compositions containing them
IL110481A0 (en)	1994-10-21	1-Benzenesulfonyl-1,3-dihydro-2h-benzimidazol-2-one derivatives, their preparation and pharmaceutical compositions containing them
IL101380A0 (en)	1992-11-15	Bis-naphthalimides,their preparation and pharmaceutical compositions containing them
IL104843A0 (en)	1993-06-10	Sulphonylbenzyl-substituted pyridones,their preparation and pharmaceutical compositions containing them
IL100262A0 (en)	1992-09-06	Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them
IL97050A0 (en)	1992-03-29	4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation
IL98499A0 (en)	1992-07-15	Aminobenzodiazepines,their preparation and pharmaceutical compositions containing them
IL98542A0 (en)	1992-07-15	Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL108703A0 (en)	1994-05-30	Substituted azolone derivatives, their preparation and pharmaceutical compositions containing them
IL103502A0 (en)	1993-03-15	Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL106408A0 (en)	1993-11-15	Benzimidazoles,their preparation and pharmaceutical compositions containing them
IL105356A0 (en)	1993-08-18	Benzimidazoles,their preparation and pharmaceutical compositions containing them
IL105647A0 (en)	1993-09-22	Biphenylmethyl-substituted pyridones,their preparation and pharmaceutical compositions containing them
IL102500A0 (en)	1993-01-14	3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them
IL104042A0 (en)	1993-05-13	Substituted diphenylsulfides,their preparation and pharmaceutical compositions containing them
IL105774A0 (en)	1993-09-22	Thienothiazine derivatives,their preparation and pharmaceutical compositions containing them
IL104347A0 (en)	1993-05-13	Substituted benzimidazole derivatives,their preparation and pharmaceutical compositions containing them
IL105370A0 (en)	1993-08-18	Propenoyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL107175A0 (en)	1994-01-25	Benzimidazoles, their preparation and pharmaceutical compositions comprising them
HUT70031A (en)	1995-09-28	Alfa, omega-diarylalkane derivatives, their preparation and pharmaceutical compositions containing them
IL105977A0 (en)	1993-10-20	Benzodiazepines,their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title
1998-12-27	FF	Patent granted
1999-12-22	KB	Patent renewed
2004-03-28	RH1	Patent not in force