IE791205L - Novel oxothia compounds, processes for their preparation,¹pharmaceutical preparations containing these compounds and¹such compounds for therapeutic use - Google Patents
Novel oxothia compounds, processes for their preparation,¹pharmaceutical preparations containing these compounds and¹such compounds for therapeutic useInfo
- Publication number
- IE791205L IE791205L IE791205A IE120579A IE791205L IE 791205 L IE791205 L IE 791205L IE 791205 A IE791205 A IE 791205A IE 120579 A IE120579 A IE 120579A IE 791205 L IE791205 L IE 791205L
- Authority
- IE
- Ireland
- Prior art keywords
- compounds
- and1such
- novel
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
2-Oxo-2,3-dihydro- benzo[b]thiophen compounds of the formula <IMAGE> in which Ph is a substituted or unsubstituted 1,2-phenylene radical, X is oxygen or sulfur, R1 is a substituted or unsubstituted heteroaryl radical bonded via a carbon atom and R2 is hydrogen, and their salts with bases have peripheral analgesic properties. They can be prepared by methods known per se and can be used as the active ingredient in pharmaceutical preparations.
[GB2024220A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH710378A CH634840A5 (en) | 1978-06-29 | 1978-06-29 | 2-OXO-2,3-DIHYDRO-BENZO (B) THIOPHENE COMPOUND AND PHARMACEUTICAL PREPARATIONS MADE THEREOF. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE791205L true IE791205L (en) | 1979-12-29 |
| IE48767B1 IE48767B1 (en) | 1985-05-15 |
Family
ID=4320005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1205/79A IE48767B1 (en) | 1978-06-29 | 1979-08-08 | Novel oxothia compounds,processes for their preparation,pharmaceutical preparations containing these compounds and such compounds for therapeutic use |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS559075A (en) |
| AR (1) | AR231540A1 (en) |
| AT (3) | AT373598B (en) |
| AU (1) | AU531535B2 (en) |
| BE (1) | BE877339R (en) |
| CA (1) | CA1125761A (en) |
| CH (1) | CH634840A5 (en) |
| CY (1) | CY1288A (en) |
| DD (1) | DD144544A6 (en) |
| DE (1) | DE2924496A1 (en) |
| DK (1) | DK152047C (en) |
| ES (1) | ES481936A2 (en) |
| FI (1) | FI792011A (en) |
| FR (1) | FR2429792A2 (en) |
| GB (1) | GB2024220B (en) |
| GR (1) | GR82335B (en) |
| HK (1) | HK42585A (en) |
| HU (1) | HU181663B (en) |
| IE (1) | IE48767B1 (en) |
| MY (1) | MY8500212A (en) |
| NL (1) | NL7905084A (en) |
| NO (1) | NO151323C (en) |
| PL (3) | PL216378A3 (en) |
| SE (1) | SE445737B (en) |
| SG (1) | SG15985G (en) |
| ZA (1) | ZA793230B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
| US6713505B2 (en) | 2000-06-28 | 2004-03-30 | Eli Lilly And Company | spla2 inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2713584C2 (en) * | 1976-04-09 | 1986-09-04 | Ciba-Geigy Ag, Basel | Benzo [b] thiophenecarboxamides, processes for their preparation and pharmaceutical preparations containing them |
| JPS6218556A (en) * | 1985-07-18 | 1987-01-27 | Fuji Photo Film Co Ltd | Silver halide color photographic sensitive material |
-
1978
- 1978-06-29 CH CH710378A patent/CH634840A5/en not_active IP Right Cessation
-
1979
- 1979-06-16 PL PL21637879A patent/PL216378A3/xx unknown
- 1979-06-16 PL PL21637679A patent/PL216376A3/xx unknown
- 1979-06-16 PL PL21637779A patent/PL216377A3/xx unknown
- 1979-06-18 DE DE19792924496 patent/DE2924496A1/en active Granted
- 1979-06-22 CY CY1288A patent/CY1288A/en unknown
- 1979-06-22 GB GB7921851A patent/GB2024220B/en not_active Expired
- 1979-06-25 FI FI792011A patent/FI792011A/en not_active Application Discontinuation
- 1979-06-26 ES ES481936A patent/ES481936A2/en not_active Expired
- 1979-06-27 FR FR7916603A patent/FR2429792A2/en active Granted
- 1979-06-27 GR GR59451A patent/GR82335B/el unknown
- 1979-06-27 CA CA330,705A patent/CA1125761A/en not_active Expired
- 1979-06-27 DD DD79213935A patent/DD144544A6/en unknown
- 1979-06-27 SE SE7905631A patent/SE445737B/en not_active IP Right Cessation
- 1979-06-28 NO NO792178A patent/NO151323C/en unknown
- 1979-06-28 AT AT0451779A patent/AT373598B/en not_active IP Right Cessation
- 1979-06-28 ZA ZA793230A patent/ZA793230B/en unknown
- 1979-06-28 DK DK274279A patent/DK152047C/en not_active IP Right Cessation
- 1979-06-28 BE BE0/196017A patent/BE877339R/en not_active IP Right Cessation
- 1979-06-28 HU HU79CI1943A patent/HU181663B/en unknown
- 1979-06-28 AT AT0451679A patent/AT373597B/en not_active IP Right Cessation
- 1979-06-28 AT AT0451579A patent/AT374199B/en not_active IP Right Cessation
- 1979-06-28 AU AU48509/79A patent/AU531535B2/en not_active Expired
- 1979-06-29 NL NL7905084A patent/NL7905084A/en not_active Application Discontinuation
- 1979-06-29 JP JP8154679A patent/JPS559075A/en active Granted
- 1979-06-29 AR AR277124A patent/AR231540A1/en active
- 1979-08-08 IE IE1205/79A patent/IE48767B1/en unknown
-
1985
- 1985-03-01 SG SG159/85A patent/SG15985G/en unknown
- 1985-05-30 HK HK425/85A patent/HK42585A/en unknown
- 1985-12-30 MY MY212/85A patent/MY8500212A/en unknown
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