IE790908L - Colchicine and vinblastine compositions - Google Patents
Colchicine and vinblastine compositionsInfo
- Publication number
- IE790908L IE790908L IE790908A IE90879A IE790908L IE 790908 L IE790908 L IE 790908L IE 790908 A IE790908 A IE 790908A IE 90879 A IE90879 A IE 90879A IE 790908 L IE790908 L IE 790908L
- Authority
- IE
- Ireland
- Prior art keywords
- colchicine
- vinblastine
- compositions
- gb2020180a
- glaucoma
- Prior art date
Links
- IAKHMKGGTNLKSZ-INIZCTEOSA-N (S)-colchicine Chemical compound C1([C@@H](NC(C)=O)CC2)=CC(=O)C(OC)=CC=C1C1=C2C=C(OC)C(OC)=C1OC IAKHMKGGTNLKSZ-INIZCTEOSA-N 0.000 title abstract 4
- JXLYSJRDGCGARV-WWYNWVTFSA-N Vinblastine Natural products O=C(O[C@H]1[C@](O)(C(=O)OC)[C@@H]2N(C)c3c(cc(c(OC)c3)[C@]3(C(=O)OC)c4[nH]c5c(c4CCN4C[C@](O)(CC)C[C@H](C3)C4)cccc5)[C@@]32[C@H]2[C@@]1(CC)C=CCN2CC3)C JXLYSJRDGCGARV-WWYNWVTFSA-N 0.000 title abstract 2
- 229960001338 colchicine Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960003048 vinblastine Drugs 0.000 title abstract 2
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 title abstract 2
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a therapeutic composition comprising a topically administrable ophthalmic pharmaceutical carrier and an effective amount of an alkaloid selected from colchicine or vinblastine for temporarily alleviating the symptoms of glaucoma in humans.
[GB2020180A]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/903,586 US4188394A (en) | 1978-05-08 | 1978-05-08 | Ophthalmic composition and method of use |
US05/904,586 US4190673A (en) | 1978-05-10 | 1978-05-10 | Colchicine ophthalmic composition and method of use |
Publications (2)
Publication Number | Publication Date |
---|---|
IE790908L true IE790908L (en) | 1979-11-08 |
IE48222B1 IE48222B1 (en) | 1984-10-31 |
Family
ID=27129366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE908/79A IE48222B1 (en) | 1978-05-08 | 1979-08-08 | Ophthalmic compositions containing colchicine and vinblastine |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU527129B2 (en) |
CA (1) | CA1139668A (en) |
DE (1) | DE2918264A1 (en) |
FR (1) | FR2425243A1 (en) |
GB (1) | GB2020180B (en) |
IE (1) | IE48222B1 (en) |
IT (1) | IT1113376B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1170152B (en) * | 1982-07-19 | 1987-06-03 | Lilly Co Eli | IMPROVEMENTS TO OR CONCERNING VINCA-ALCALOID FORMULATIONS |
GB8710780D0 (en) * | 1987-05-07 | 1987-06-10 | Scras | Opthalmological application of eicosapentaenoic acid |
IL83086A (en) * | 1987-07-06 | 1991-03-10 | Teva Pharma | Stable,injectable solutions of vincristine salts |
US4918165A (en) * | 1987-07-16 | 1990-04-17 | Ophthalmic Research Corporation | Mitotic inhibitor and method for preventing posterior lens capsule opacification after extracapsular extraction |
FR2623089B1 (en) * | 1987-11-13 | 1990-04-27 | Pf Medicament | PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION OF NAVELBINE |
-
1979
- 1979-04-25 GB GB7914444A patent/GB2020180B/en not_active Expired
- 1979-05-03 AU AU46651/79A patent/AU527129B2/en not_active Ceased
- 1979-05-07 CA CA000327076A patent/CA1139668A/en not_active Expired
- 1979-05-07 FR FR7911494A patent/FR2425243A1/en active Granted
- 1979-05-07 DE DE19792918264 patent/DE2918264A1/en not_active Ceased
- 1979-05-08 IT IT22443/79A patent/IT1113376B/en active
- 1979-08-08 IE IE908/79A patent/IE48222B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2425243B1 (en) | 1984-07-20 |
DE2918264A1 (en) | 1979-11-15 |
CA1139668A (en) | 1983-01-18 |
IT1113376B (en) | 1986-01-20 |
IE48222B1 (en) | 1984-10-31 |
AU4665179A (en) | 1979-11-15 |
GB2020180A (en) | 1979-11-14 |
FR2425243A1 (en) | 1979-12-07 |
AU527129B2 (en) | 1983-02-17 |
GB2020180B (en) | 1982-08-25 |
IT7922443A0 (en) | 1979-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3069895D1 (en) | Pharmaceutical compositions comprising steroid alkaloids | |
PH14086A (en) | Cyclosporin derivatives and pharmaceutical compositions thereof | |
GB2074027B (en) | Topical pharmaceutical compositions containing corticosteroids and phosphatides | |
IL57020A0 (en) | New carbazolyl-(4)-oxypropanolamine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same | |
GB2050828B (en) | Process for the preparations of finely divided pharmaceutical compositions | |
DE2966497D1 (en) | 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds | |
NZ185832A (en) | Pharmaceutical composition for the treatment of urogenital disorders extract from plant(s) of rosaceae family plus mono-aminated amino acids | |
ES481155A1 (en) | Imidazo (2.1-b)-(1.3.4)-thiadiazoles, process for their preparation and their use in medicaments. | |
GB2075341B (en) | Pharmaceutical compositions | |
PH14723A (en) | Pharmacologically active compounds and compositions containing same | |
DE2963572D1 (en) | Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions | |
IE802379L (en) | Prednisolone diesters | |
JPS55111494A (en) | Monophosphonate compound* its manufacture and therapeutic composition containing same as active ingredient | |
IE790908L (en) | Colchicine and vinblastine compositions | |
GB2041219B (en) | Topical pharmaceutical compositions containing thiazolidine-substituted corticosteroids | |
GB2049419B (en) | Compositions for use as cosmetics and a process for the preparation of their active ingredients | |
GB2058564B (en) | Pharmaceutical compositions comprising anti-osteoporotic agents | |
NZ192927A (en) | Hydroxy derivatives of 2-isopropylamino-pyrimidine pharmaceutical compositions | |
ZA792043B (en) | Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them | |
GB2022998B (en) | Phermaceutical composition for the treatment of neoplasticand other diseases | |
IL57939A0 (en) | Pharmaceutical compositions containing n-substituted aziridine-2-carboxylic acid derivatives and processes for the preparation of said n-substituted aziridine-2-carboxylic acid derivatives | |
EP0378413A3 (en) | Compositions for topical treatment of skin disorders | |
IL66071A (en) | Method and compositions for the topical treatment of glaucoma comprising aminoacid derivatives | |
HU175304B (en) | Process for producing condensed benzene-xantene-derivatives and pharmaceutical compositions containing them as active agents | |
PT72066A (en) | Process for the preparation of novel halophenyl-pyridil-allylamine derivatives and pharmaceutical compositions thereof |