IE42957L - Rosamicin (antibiotic 67-694) derivatives. - Google Patents
Rosamicin (antibiotic 67-694) derivatives.Info
- Publication number
- IE42957L IE42957L IE760375A IE37576A IE42957L IE 42957 L IE42957 L IE 42957L IE 760375 A IE760375 A IE 760375A IE 37576 A IE37576 A IE 37576A IE 42957 L IE42957 L IE 42957L
- Authority
- IE
- Ireland
- Prior art keywords
- derivatives
- compounds
- general formula
- image
- addition salts
- Prior art date
Links
- IUPCWCLVECYZRV-JZMZINANSA-N rosaramicin Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H]([C@@H]2O[C@@]2(C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O IUPCWCLVECYZRV-JZMZINANSA-N 0.000 title abstract 3
- ZUHRLTIPDRLJHR-UHFFFAOYSA-N Rosamicin Natural products CCC1OC(=O)CC(O)C(C)C(OC2OC(C)CC(C2O)N(C)C)C(CC=O)CC(C)C(=O)C=CC3OC3C1C ZUHRLTIPDRLJHR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 230000007096 poisonous effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Derivatives of rosaramicin of the general formula <IMAGE> in which the meaning of the individual symbols is contained in Claim 1, are prepared by reducing an appropriately substituted compound of the general formula <IMAGE> or non-poisonous, pharmaceutically harmless acid addition salts of these compounds, by means of treating them with a reducing agent in the presence of acid, whereby the ester groups contained in the starting material are solvolysed, and isolating the compounds thus obtained in free form or as acid addition salts, or converting them into their esters. The novel compounds possess anti-bacterial activity.
[GB1544819A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55425075A | 1975-02-28 | 1975-02-28 | |
| US05/554,266 US3975372A (en) | 1975-02-28 | 1975-02-28 | Preparation of 12,13-desepoxy-12,13-dehydrorosamicin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42957L true IE42957L (en) | 1976-08-28 |
| IE42957B1 IE42957B1 (en) | 1980-11-19 |
Family
ID=27070531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE375/76A IE42957B1 (en) | 1975-02-28 | 1976-02-25 | Novel antibiotic substances derived from antibiotic 67-694 (rosamicin) and processes for their preparation |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS51110585A (en) |
| AR (1) | AR215851A1 (en) |
| AT (1) | AT344321B (en) |
| AU (1) | AU499566B2 (en) |
| CA (1) | CA1075234A (en) |
| CH (1) | CH630391A5 (en) |
| DD (1) | DD125959A5 (en) |
| DE (1) | DE2607459A1 (en) |
| DK (1) | DK79876A (en) |
| ES (1) | ES445489A1 (en) |
| FI (1) | FI63421C (en) |
| FR (1) | FR2302102A1 (en) |
| GB (1) | GB1544819A (en) |
| HU (1) | HU176333B (en) |
| IE (1) | IE42957B1 (en) |
| IL (1) | IL49104A (en) |
| LU (1) | LU74420A1 (en) |
| NL (1) | NL7601863A (en) |
| NO (1) | NO141718C (en) |
| PT (1) | PT64836B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4279896A (en) * | 1980-06-23 | 1981-07-21 | Schering Corporation | Novel 20-imino macrolide antibacterial agents |
| JPS58219197A (en) * | 1982-06-15 | 1983-12-20 | Sanraku Inc | Macrolide antibiotic derivatives |
| US4436729A (en) * | 1982-06-30 | 1984-03-13 | Schering Corporation | 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use |
| US4454314A (en) * | 1982-08-02 | 1984-06-12 | Pfizer Inc. | Antibacterial mycaminosyl tylonolide and related macrolide derivatives |
| YU45033B (en) * | 1987-04-14 | 1991-06-30 | Pliva Zagreb | Process for preparing 10,11,12,13-tetrahydro derivative |
| EP0292352A3 (en) * | 1987-05-06 | 1988-12-28 | Adir Et Compagnie | Macrolide derivatives, process for their preparation and their pharmaceutical compositions |
| FR2626576B1 (en) * | 1987-05-06 | 1991-07-12 | Adir | NOVEL CARBOMYCIN B DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| US5195268A (en) * | 1991-11-21 | 1993-03-23 | Ellis Gregory T | Weedless hook for lures |
| US5218778A (en) * | 1992-05-28 | 1993-06-15 | Szantor Alfons J | Fishing lure |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205976A1 (en) * | 1972-11-15 | 1976-06-23 | Scherico Ltd | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 3-MONOESTERS OF ROSAMYCIN THAT HAVE ANTIBACTERIAL ACTIVITY |
-
1976
- 1976-02-18 CH CH206676A patent/CH630391A5/en not_active IP Right Cessation
- 1976-02-24 CA CA246,429A patent/CA1075234A/en not_active Expired
- 1976-02-24 NO NO760606A patent/NO141718C/en unknown
- 1976-02-24 DE DE19762607459 patent/DE2607459A1/en not_active Withdrawn
- 1976-02-24 LU LU74420A patent/LU74420A1/xx unknown
- 1976-02-24 ES ES445489A patent/ES445489A1/en not_active Expired
- 1976-02-24 AR AR262356A patent/AR215851A1/en active
- 1976-02-24 FI FI760473A patent/FI63421C/en not_active IP Right Cessation
- 1976-02-24 GB GB7260/76A patent/GB1544819A/en not_active Expired
- 1976-02-24 PT PT64836A patent/PT64836B/en unknown
- 1976-02-24 AT AT133376A patent/AT344321B/en not_active IP Right Cessation
- 1976-02-24 FR FR7605091A patent/FR2302102A1/en active Granted
- 1976-02-24 NL NL7601863A patent/NL7601863A/en not_active Application Discontinuation
- 1976-02-25 IE IE375/76A patent/IE42957B1/en unknown
- 1976-02-25 IL IL49104A patent/IL49104A/en unknown
- 1976-02-25 AU AU11419/76A patent/AU499566B2/en not_active Expired
- 1976-02-25 JP JP51019830A patent/JPS51110585A/ja active Pending
- 1976-02-25 DK DK79876*#A patent/DK79876A/en not_active Application Discontinuation
- 1976-02-26 DD DD191537A patent/DD125959A5/xx unknown
- 1976-02-26 HU HU76SCHE556A patent/HU176333B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO141718B (en) | 1980-01-21 |
| DK79876A (en) | 1976-08-29 |
| CH630391A5 (en) | 1982-06-15 |
| NO760606L (en) | 1976-08-31 |
| GB1544819A (en) | 1979-04-25 |
| AR215851A1 (en) | 1979-11-15 |
| HU176333B (en) | 1981-01-28 |
| ES445489A1 (en) | 1977-11-16 |
| ATA133376A (en) | 1977-11-15 |
| DE2607459A1 (en) | 1976-09-09 |
| AU499566B2 (en) | 1979-04-26 |
| PT64836B (en) | 1977-06-07 |
| FR2302102A1 (en) | 1976-09-24 |
| FI63421B (en) | 1983-02-28 |
| DD125959A5 (en) | 1977-06-08 |
| CA1075234A (en) | 1980-04-08 |
| IL49104A0 (en) | 1976-04-30 |
| LU74420A1 (en) | 1977-01-07 |
| IE42957B1 (en) | 1980-11-19 |
| JPS51110585A (en) | 1976-09-30 |
| NL7601863A (en) | 1976-08-31 |
| PT64836A (en) | 1976-03-01 |
| IL49104A (en) | 1979-12-30 |
| NO141718C (en) | 1980-04-30 |
| FI63421C (en) | 1983-06-10 |
| AT344321B (en) | 1978-07-10 |
| FR2302102B1 (en) | 1978-12-01 |
| AU1141976A (en) | 1977-09-01 |
| FI760473A7 (en) | 1976-08-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5569586A (en) | 11* 66 and 22substitutedd11carbaa22penenn 33carboxylic acid | |
| SE8105829L (en) | PROCEDURE FOR THE PREPARATION OF CLAVULANIC ACID OR A SALT THEREOF | |
| ES474288A1 (en) | 3-Substituted-6-substituted-7-oxo-1-azabicyclo (3.2.0)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it. | |
| ES474289A1 (en) | 3-Substituted-6-(1'hydroxethyl)-7-oxo-1-azabicyclo(3.2.0.)-hept-2-ene-2-carboxylic acid, its preparation and pharmaceutical compositions containing it. | |
| IE780899L (en) | Azetidinopyrrole derivatives | |
| IE42957L (en) | Rosamicin (antibiotic 67-694) derivatives. | |
| JPS543087A (en) | Preparation of cephalosporin compound | |
| IE38373B1 (en) | Novel carbamic acid esters and their use as insecticides and acaricides | |
| IE44069L (en) | Noroxymorphones | |
| JPS5746988A (en) | Novel penicillin derivative and its preparation | |
| IE44295L (en) | Preparation of clavulanic acid | |
| GB1498919A (en) | Furanose-o-pyridylcarboxylic acid esters | |
| GB1514389A (en) | Glycerides with antibacterial properties | |
| GB1500965A (en) | Cyclic ether antibiotics | |
| IE43413L (en) | Behenic acid ester | |
| JPS5231024A (en) | Process for preparation of epoxysuccinic acid esters | |
| IE43117L (en) | Naphthacene derivatives | |
| IE42774L (en) | Composition containing organic dicarbonates | |
| JPS5728077A (en) | Novel dimethacrylic acid ester of dimethylol-tetrahydrofuran, manufacture and use as adhesive | |
| IE42666L (en) | Deoxyclavulanic acid and deoxyisoclavulanic acid and¹derivatives thereof | |
| IE40890B1 (en) | Pyrimidin(2)yl-thionophosphoric acid esters,process for their preparation and their use as insecticides,acaricides and nematocides | |
| JPS54151132A (en) | Compound having antibiotic activity | |
| JPS51143645A (en) | Process for preparation of 3,3-dimethyl- 2-(2,2-dihalo)cyclopropanecar boxylic acid ester | |
| JPS5217447A (en) | Process for preparation of trans-4- aminomethylcyclohexane-carboxylic acid ester | |
| IE46175L (en) | Preparation of 3-heterocyclylthiomethyl cephalosporins from¹3-methylene cephalosporins. |