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IE42941L - Furo-furones - Google Patents

Furo-furones

Info

Publication number
IE42941L
IE42941L IE760074A IE7476A IE42941L IE 42941 L IE42941 L IE 42941L IE 760074 A IE760074 A IE 760074A IE 7476 A IE7476 A IE 7476A IE 42941 L IE42941 L IE 42941L
Authority
IE
Ireland
Prior art keywords
formula
compounds
image
alpha
furones
Prior art date
Application number
IE760074A
Other versions
IE42941B1 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA00750317A external-priority patent/ZA75317B/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE42941L publication Critical patent/IE42941L/en
Publication of IE42941B1 publication Critical patent/IE42941B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Compounds of the formula (I) <IMAGE> in which the group B is in the alpha or beta position and is a hydrocarbon radical which is substituted by one or more free or protected hydroxyl groups, of which at least one is present on the alpha carbon atom, are prepared by treating compounds of the formula (II) <IMAGE> in which the symbols Y and Z have the meaning stated in Claim 1, with an aqueous acid. The compounds of the formula (I) are valuable as intermediates for the synthesis of prostaglandins and prostaglandin analogues. [GB1532551A]
IE74/76A 1975-01-16 1976-01-15 Furo/3,4-6/furone derivatives and their preparation IE42941B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA00750317A ZA75317B (en) 1975-01-16 1975-01-16 Novel chemical compounds and their use as intermediates
ZA751985 1975-04-01

Publications (2)

Publication Number Publication Date
IE42941L true IE42941L (en) 1976-07-16
IE42941B1 IE42941B1 (en) 1980-11-19

Family

ID=27131118

Family Applications (1)

Application Number Title Priority Date Filing Date
IE74/76A IE42941B1 (en) 1975-01-16 1976-01-15 Furo/3,4-6/furone derivatives and their preparation

Country Status (9)

Country Link
JP (1) JPS5195060A (en)
CH (1) CH628639A5 (en)
DE (1) DE2601333A1 (en)
DK (1) DK17876A (en)
FR (2) FR2318172A1 (en)
GB (1) GB1532551A (en)
IE (1) IE42941B1 (en)
LU (1) LU74144A1 (en)
NL (1) NL7600367A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048194A (en) * 1976-04-14 1977-09-13 The Upjohn Company 6α-Methoxy-4α-hydroxy-2β-hydroxymethyl-3.alpha.-tetrahydropyranacetic acid 4α γ-lactone ethers and acylates
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US5814660A (en) * 1995-12-22 1998-09-29 Alcon Laboratories, Inc. 9-oxa prostaglandin analogs as ocular hypotensives
DE69633136T2 (en) * 1995-12-22 2005-09-01 Alcon Laboratories, Inc., Fort Worth SUBSTITUTED TETRAHYDROFURAN ANALOGS OF PROSTAGLANDINES AS EYE PRESENTING MEDICAMENTS
US5866602A (en) * 1995-12-22 1999-02-02 Alcon Laboratories, Inc. Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2436332A1 (en) * 1974-07-27 1976-02-12 Knoll Ag SUBSTITUTED TETRAHYDROFURANS AND PROCESS FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
IE42941B1 (en) 1980-11-19
JPS5195060A (en) 1976-08-20
FR2318164B1 (en) 1979-02-16
CH628639A5 (en) 1982-03-15
FR2318172B1 (en) 1979-03-23
DE2601333A1 (en) 1976-07-22
FR2318172A1 (en) 1977-02-11
DK17876A (en) 1976-07-17
FR2318164A1 (en) 1977-02-11
LU74144A1 (en) 1977-07-22
NL7600367A (en) 1976-07-20
GB1532551A (en) 1978-11-15

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