IE38427L - Amidophenylisothioureas - Google Patents
AmidophenylisothioureasInfo
- Publication number
- IE38427L IE38427L IE731935A IE193573A IE38427L IE 38427 L IE38427 L IE 38427L IE 731935 A IE731935 A IE 731935A IE 193573 A IE193573 A IE 193573A IE 38427 L IE38427 L IE 38427L
- Authority
- IE
- Ireland
- Prior art keywords
- carbon atoms
- radical
- radicals
- alkyl
- substituent selected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Abstract
1393329 Isothioureas BAYER AG 26 Oct 1973 [27 Oct 1972] 49935/73 Heading C2C The invention comprises novel compounds (I) in which X is an alkyl radical with 1 to 6 carbon atoms; R is an alkyl radical with 1 to 12 carbon atoms, or a cycloalkyl radical with up to 8 carbon atoms, or an alkenyl radical with up to 12 carbon atoms, or an aralkyl radical (optionally carrying in its aryl part at least one substituent selected from alkyl and alkoxy groups, each with 1 to 4 carbon atoms, and halogen atoms); R<SP>1</SP> is an alkyl radical with 1 to 4 carbon atoms; and R<SP>2</SP> is a hydrogen atom or an alkyl radical with 1 to 18 carbon atoms (optionally carrying at least one substituent selected from halogen and nitrile radicals, alkoxy radicals with 1 to 4 carbon atoms, alkoxycarbonyl radicals with 2 to 5 carbon atoms, and phenoxy, halophenoxy, alkylphenoxy and alkoxyphenoxy radicals), or a cycloalkyl radical with 5 to 8 carbon atoms, or an aralkyl radical (optionally carrying at least one substituent selected from halogen atoms, alkyl radicals with 1 to 4 carbon atoms, and alkoxy radicals with 1 to 4 carbon atoms), or an aryl radical (optionally carrying at least one substituent selected from halogen atoms and alkyl and alkoxy radicals with 1 to 4 carbon atoms each) or a 1-furyl radical. They are made by alkylating the corresponding thioureas. Pharmaceutical preparations showing anthelmintic action contain (I) as active ingredient; standard administration forms are described.
[GB1393329A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2252691A DE2252691A1 (en) | 1972-10-27 | 1972-10-27 | AMIDOPHENYLISOTHIOURA, METHOD OF MANUFACTURING AND USE AS A MEDICINAL PRODUCT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38427L true IE38427L (en) | 1974-04-27 |
| IE38427B1 IE38427B1 (en) | 1978-03-15 |
Family
ID=5860198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1935/73A IE38427B1 (en) | 1972-10-27 | 1973-10-26 | New amidophenylisothioureas their procuction and their medicinal use |
Country Status (23)
| Country | Link |
|---|---|
| JP (2) | JPS4980216A (en) |
| AR (1) | AR199590A1 (en) |
| AT (1) | AT330199B (en) |
| AU (1) | AU475884B2 (en) |
| BE (1) | BE806549A (en) |
| CA (1) | CA1016349A (en) |
| CH (1) | CH588458A5 (en) |
| CS (1) | CS165965B2 (en) |
| DE (1) | DE2252691A1 (en) |
| DK (1) | DK134398C (en) |
| ES (1) | ES419990A1 (en) |
| FR (1) | FR2204420B1 (en) |
| GB (1) | GB1393329A (en) |
| HU (1) | HU167555B (en) |
| IE (1) | IE38427B1 (en) |
| IL (1) | IL43483A (en) |
| KE (1) | KE2586A (en) |
| LU (1) | LU68690A1 (en) |
| NL (1) | NL7314614A (en) |
| PH (1) | PH10384A (en) |
| PL (1) | PL91111B1 (en) |
| SU (1) | SU490285A3 (en) |
| ZA (1) | ZA738287B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2434183C2 (en) * | 1974-07-16 | 1982-07-01 | Bayer Ag, 5090 Leverkusen | Substituted phenylisothioureas, a process for their preparation and their use as pharmaceuticals |
-
1972
- 1972-10-27 DE DE2252691A patent/DE2252691A1/en active Pending
-
1973
- 1973-10-23 AR AR250650A patent/AR199590A1/en active
- 1973-10-23 SU SU1966532A patent/SU490285A3/en active
- 1973-10-24 NL NL7314614A patent/NL7314614A/xx unknown
- 1973-10-24 AU AU61768/73A patent/AU475884B2/en not_active Expired
- 1973-10-24 PH PH15148A patent/PH10384A/en unknown
- 1973-10-25 JP JP48119502A patent/JPS4980216A/ja active Pending
- 1973-10-25 CH CH1504773A patent/CH588458A5/xx not_active IP Right Cessation
- 1973-10-25 CA CA184,274A patent/CA1016349A/en not_active Expired
- 1973-10-25 IL IL43483A patent/IL43483A/en unknown
- 1973-10-25 JP JP48119501A patent/JPS4976836A/ja active Pending
- 1973-10-25 LU LU68690A patent/LU68690A1/xx unknown
- 1973-10-25 AT AT904173A patent/AT330199B/en not_active IP Right Cessation
- 1973-10-26 HU HUBA2989A patent/HU167555B/hu unknown
- 1973-10-26 DK DK580973A patent/DK134398C/en active
- 1973-10-26 GB GB4993573A patent/GB1393329A/en not_active Expired
- 1973-10-26 PL PL1973166117A patent/PL91111B1/pl unknown
- 1973-10-26 ZA ZA738287A patent/ZA738287B/en unknown
- 1973-10-26 BE BE137089A patent/BE806549A/en unknown
- 1973-10-26 CS CS7387A patent/CS165965B2/cs unknown
- 1973-10-26 IE IE1935/73A patent/IE38427B1/en unknown
- 1973-10-26 FR FR7338264A patent/FR2204420B1/fr not_active Expired
- 1973-10-26 ES ES419990A patent/ES419990A1/en not_active Expired
-
1975
- 1975-12-02 KE KE2586*UA patent/KE2586A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1393329A (en) | 1975-05-07 |
| CA1016349A (en) | 1977-08-30 |
| DE2252691A1 (en) | 1974-05-02 |
| DK134398B (en) | 1976-11-01 |
| FR2204420B1 (en) | 1977-09-09 |
| ZA738287B (en) | 1974-09-25 |
| AR199590A1 (en) | 1974-09-13 |
| FR2204420A1 (en) | 1974-05-24 |
| AU475884B2 (en) | 1976-09-09 |
| NL7314614A (en) | 1974-05-01 |
| AT330199B (en) | 1976-06-25 |
| JPS4980216A (en) | 1974-08-02 |
| IL43483A0 (en) | 1974-01-14 |
| ATA904173A (en) | 1975-09-15 |
| HU167555B (en) | 1975-11-28 |
| KE2586A (en) | 1975-12-19 |
| SU490285A3 (en) | 1975-10-30 |
| IL43483A (en) | 1976-08-31 |
| PH10384A (en) | 1977-03-02 |
| JPS4976836A (en) | 1974-07-24 |
| AU6176873A (en) | 1975-04-24 |
| CS165965B2 (en) | 1975-12-22 |
| DK134398C (en) | 1977-03-28 |
| CH588458A5 (en) | 1977-06-15 |
| ES419990A1 (en) | 1976-03-16 |
| BE806549A (en) | 1974-04-26 |
| PL91111B1 (en) | 1977-02-28 |
| IE38427B1 (en) | 1978-03-15 |
| LU68690A1 (en) | 1974-01-08 |
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