IE35480B1 - 3'-4'-dideoxykanamycin b active against resistant bacteria and its synthesis - Google Patents
3'-4'-dideoxykanamycin b active against resistant bacteria and its synthesisInfo
- Publication number
- IE35480B1 IE35480B1 IE964/71A IE96471A IE35480B1 IE 35480 B1 IE35480 B1 IE 35480B1 IE 964/71 A IE964/71 A IE 964/71A IE 96471 A IE96471 A IE 96471A IE 35480 B1 IE35480 B1 IE 35480B1
- Authority
- IE
- Ireland
- Prior art keywords
- dideoxykanamycin
- synthesis
- groups
- active against
- resistant bacteria
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Manufacture And Refinement Of Metals (AREA)
Abstract
1349302 3<SP>1</SP>-4<SP>1</SP>-Dideoxykanamycin B ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI 1 June 1973 [29 July 1970 11 May 1971] 18317/71 Heading C2A The invention comprises 3<SP>1</SP>,4<SP>1</SP> - dideoxykanamycin B of Formula IV A process for the synthesis of 3<SP>1</SP>,4<SP>1</SP>-dideoxykanamycin B starting from kanamycin B of Formula III wherein R is NH 2 - comprises protecting the amino and all or a part of the hydroxyl groups other than 3<SP>1</SP> and 4<SP>1</SP>-hydroxyl groups of kanamycin B by a conventional method, sulphonylating the 3<SP>1</SP> and 4<SP>1</SP> hydroxy groups to give a derivative having disulphonic ester groups, removing the 3<SP>1</SP>,4<SP>1</SP>-disulphonic esters by known methods to give a 3<SP>1</SP>,4<SP>1</SP>-unsaturated compound, reducing the 3<SP>1</SP>,4<SP>1</SP>-unsaturated compound and removing the residual protecting groups.
[GB1349302A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45065760A JPS507595B1 (en) | 1970-07-29 | 1970-07-29 | |
| JP3087171A JPS5146110B1 (en) | 1971-05-11 | 1971-05-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35480L IE35480L (en) | 1972-01-29 |
| IE35480B1 true IE35480B1 (en) | 1976-03-03 |
Family
ID=26369303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE964/71A IE35480B1 (en) | 1970-07-29 | 1971-07-28 | 3'-4'-dideoxykanamycin b active against resistant bacteria and its synthesis |
Country Status (23)
| Country | Link |
|---|---|
| AT (1) | AT320846B (en) |
| BE (1) | BE770692A (en) |
| BG (1) | BG19188A3 (en) |
| CA (1) | CA953294A (en) |
| CH (1) | CH552586A (en) |
| DK (1) | DK127778B (en) |
| ES (1) | ES392570A1 (en) |
| FI (1) | FI57596C (en) |
| FR (1) | FR2103935A5 (en) |
| GB (1) | GB1349302A (en) |
| HK (1) | HK57477A (en) |
| HU (1) | HU162704B (en) |
| IE (1) | IE35480B1 (en) |
| IL (1) | IL36973A (en) |
| LU (1) | LU63625A1 (en) |
| MY (1) | MY7800147A (en) |
| NL (1) | NL163219C (en) |
| NO (1) | NO134117C (en) |
| PL (1) | PL83206B1 (en) |
| RO (1) | RO63815A (en) |
| SE (1) | SE398753B (en) |
| SU (1) | SU511007A3 (en) |
| YU (1) | YU35895B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1537905A (en) * | 1975-12-09 | 1979-01-10 | Microbial Chem Res Found | Processes for the preparation of 3',4'-dideoxykanamycin b |
| JPS6029720B2 (en) * | 1975-12-11 | 1985-07-12 | 財団法人微生物化学研究会 | Novel production method of 3',4'-dideoxykanamycin B |
| JPS52153942A (en) * | 1976-06-16 | 1977-12-21 | Microbial Chem Res Found | Preparation of kanamicin c deoxy derivatives and kanamicine c or its deoxy derivatives |
| JPS6052719B2 (en) * | 1976-12-16 | 1985-11-20 | 財団法人微生物化学研究会 | Novel production method for 3',4'-dideoxykanamycin B |
| RU2458931C2 (en) * | 2006-06-02 | 2012-08-20 | Мейдзи Сейка Фарма Ко., Лтд. | New aminoglycoside antibiotics |
-
1971
- 1971-06-01 GB GB1831771A patent/GB1349302A/en not_active Expired
- 1971-06-02 IL IL36973A patent/IL36973A/en unknown
- 1971-06-18 FI FI1744/71A patent/FI57596C/en active
- 1971-06-23 ES ES392570A patent/ES392570A1/en not_active Expired
- 1971-06-25 CH CH937771A patent/CH552586A/en not_active IP Right Cessation
- 1971-06-29 NL NL7109001.A patent/NL163219C/en not_active IP Right Cessation
- 1971-07-19 HU HUZA335A patent/HU162704B/hu unknown
- 1971-07-23 SU SU1685994A patent/SU511007A3/en active
- 1971-07-26 RO RO7100067797A patent/RO63815A/en unknown
- 1971-07-27 YU YU1963/71A patent/YU35895B/en unknown
- 1971-07-28 DK DK371271AA patent/DK127778B/en unknown
- 1971-07-28 AT AT657571A patent/AT320846B/en not_active IP Right Cessation
- 1971-07-28 PL PL1971149704A patent/PL83206B1/en unknown
- 1971-07-28 IE IE964/71A patent/IE35480B1/en unknown
- 1971-07-28 NO NO2852/71A patent/NO134117C/no unknown
- 1971-07-28 FR FR7128504A patent/FR2103935A5/fr not_active Expired
- 1971-07-28 CA CA119,288A patent/CA953294A/en not_active Expired
- 1971-07-28 LU LU63625D patent/LU63625A1/xx unknown
- 1971-07-29 BE BE770692A patent/BE770692A/en unknown
- 1971-07-29 SE SE7109756A patent/SE398753B/en unknown
- 1971-07-29 BG BG018187A patent/BG19188A3/en unknown
-
1977
- 1977-11-17 HK HK574/77A patent/HK57477A/en unknown
-
1978
- 1978-12-30 MY MY147/78A patent/MY7800147A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| LU63625A1 (en) | 1971-11-26 |
| BE770692A (en) | 1971-12-01 |
| SU511007A3 (en) | 1976-04-15 |
| DE2135191B2 (en) | 1976-09-02 |
| SE398753B (en) | 1978-01-16 |
| AT320846B (en) | 1975-02-25 |
| FI57596B (en) | 1980-05-30 |
| DE2135191A1 (en) | 1972-02-03 |
| NO134117B (en) | 1976-05-10 |
| CH552586A (en) | 1974-08-15 |
| FI57596C (en) | 1980-09-10 |
| NO134117C (en) | 1976-08-18 |
| NL163219B (en) | 1980-03-17 |
| IL36973A (en) | 1974-06-30 |
| RO63815A (en) | 1979-01-15 |
| FR2103935A5 (en) | 1972-04-14 |
| BG19188A3 (en) | 1975-04-30 |
| CA953294A (en) | 1974-08-20 |
| NL7109001A (en) | 1972-02-01 |
| MY7800147A (en) | 1978-12-31 |
| GB1349302A (en) | 1974-04-03 |
| IE35480L (en) | 1972-01-29 |
| HK57477A (en) | 1977-11-25 |
| PL83206B1 (en) | 1975-12-31 |
| DK127778B (en) | 1974-01-07 |
| YU196371A (en) | 1981-02-28 |
| NL163219C (en) | 1980-08-15 |
| HU162704B (en) | 1973-03-28 |
| ES392570A1 (en) | 1974-06-16 |
| YU35895B (en) | 1981-08-31 |
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