IE33016B1 - Concentrated liquid antacid compositions - Google Patents
Concentrated liquid antacid compositionsInfo
- Publication number
- IE33016B1 IE33016B1 IE374/69A IE37469A IE33016B1 IE 33016 B1 IE33016 B1 IE 33016B1 IE 374/69 A IE374/69 A IE 374/69A IE 37469 A IE37469 A IE 37469A IE 33016 B1 IE33016 B1 IE 33016B1
- Authority
- IE
- Ireland
- Prior art keywords
- phosphate
- gluconate
- calcium
- april
- sodium
- Prior art date
Links
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title abstract 4
- 229940069428 antacid Drugs 0.000 title abstract 4
- 239000003159 antacid agent Substances 0.000 title abstract 4
- 230000001458 anti-acid effect Effects 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title abstract 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 abstract 2
- 229910000389 calcium phosphate Inorganic materials 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 2
- 229940050410 gluconate Drugs 0.000 abstract 2
- 239000001755 magnesium gluconate Substances 0.000 abstract 2
- 235000015778 magnesium gluconate Nutrition 0.000 abstract 2
- 229960003035 magnesium gluconate Drugs 0.000 abstract 2
- IAKLPCRFBAZVRW-XRDLMGPZSA-L magnesium;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanoate;hydrate Chemical compound O.[Mg+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O IAKLPCRFBAZVRW-XRDLMGPZSA-L 0.000 abstract 2
- 235000019691 monocalcium phosphate Nutrition 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- NYRAVIYBIHCEGB-UHFFFAOYSA-N [K].[Ca] Chemical compound [K].[Ca] NYRAVIYBIHCEGB-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 229940124575 antispasmodic agent Drugs 0.000 abstract 1
- 239000008135 aqueous vehicle Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000004227 calcium gluconate Substances 0.000 abstract 1
- 235000013927 calcium gluconate Nutrition 0.000 abstract 1
- 229960004494 calcium gluconate Drugs 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000019634 flavors Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000004224 potassium gluconate Substances 0.000 abstract 1
- 235000013926 potassium gluconate Nutrition 0.000 abstract 1
- 229960003189 potassium gluconate Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 239000000176 sodium gluconate Substances 0.000 abstract 1
- 235000012207 sodium gluconate Nutrition 0.000 abstract 1
- 229940005574 sodium gluconate Drugs 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003204 tranquilizing agent Substances 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,200,157. Pharmaceutical vehicle; antacid composition. SMITH KLINE & FRENCH LABORATORIES. 1 April, 1969 [5 April, 1968], No. 17074/69. Heading A5B. An aqueous pharmaceutical vehicle comprises a combination of monobasic calcium phosphate and at least one of sodium, potassium, calcium or magnesium gluconate dissolved in water, wherein the phosphate and gluconate are each present in an amount from 0.5-7.0% W/V, provided that the total concentration of phosphate and gluconate is from 3-10% W/V. A liquid antacid composition comprises weight/volume of from 25-50% of solid antacid material suspended in an aqueous vehicle containing monobasic calcium phosphate and at least one of sodium, potassium calcium or magnesium gluconate. Conventional additives such as preservatives, flavours and solubilizers and anti-spasmodic agents or tranquilizers or glycine may also be present.
[GB1200157A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71923468A | 1968-04-05 | 1968-04-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE33016L IE33016L (en) | 1969-10-05 |
| IE33016B1 true IE33016B1 (en) | 1974-02-20 |
Family
ID=24889291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE374/69A IE33016B1 (en) | 1968-04-05 | 1969-03-21 | Concentrated liquid antacid compositions |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3621094A (en) |
| AU (1) | AU443154B2 (en) |
| BE (1) | BE731060A (en) |
| DE (1) | DE1915798C3 (en) |
| FR (1) | FR2005599A1 (en) |
| GB (1) | GB1200157A (en) |
| IE (1) | IE33016B1 (en) |
| IL (1) | IL31858A (en) |
| LU (1) | LU58367A1 (en) |
| NL (1) | NL6905135A (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1076479A (en) * | 1976-09-17 | 1980-04-29 | Lewis/Howe Company | Concentrated magnesium hydroxide suspensions or emulsions and method for production thereof |
| JPS58192739U (en) * | 1982-06-19 | 1983-12-21 | 仁川 春夫 | Vehicle towing repair car |
| DE3343793A1 (en) * | 1983-12-03 | 1985-08-01 | Franz 8400 Regensburg Schöberl | Towing-away device for motor vehicles |
| US4548817A (en) * | 1984-01-20 | 1985-10-22 | Webb-Waring Lung Institute | Composition and method for treating mammalian acidosis |
| EP0215925A4 (en) * | 1985-03-27 | 1987-10-26 | Baxter Travenol Lab | Supplemental calcium addition unit. |
| JPS62502967A (en) * | 1985-04-18 | 1987-11-26 | ザ・プロクター・アンド・ギャンブル・カンパニー | Treatment of non-ulcer dyspepsia |
| US5762962A (en) * | 1994-10-05 | 1998-06-09 | Warner-Lambert Company | Antacid pharmaceutical composition |
| CA2168959A1 (en) * | 1993-10-13 | 1995-04-20 | Constantine Georgiades | Antacid pharmaceutical composition |
| US5455050A (en) * | 1993-11-12 | 1995-10-03 | Mcneil-Ppc, Inc. | Aqueous antacids with calcium carbonate and magnesium salt |
| US5498426A (en) * | 1994-10-03 | 1996-03-12 | The Procter & Gamble Company | Liquid antacid compositions |
| US20060257358A1 (en) * | 2005-05-13 | 2006-11-16 | Depuy Products, Inc. | Suspension of calcium phosphate particulates for local delivery of therapeutic agents |
| US8790714B2 (en) * | 2007-08-03 | 2014-07-29 | Nucitec, S.A. De C.V. | Compositions and methods for treatment and prevention of osteoarthritis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3062714A (en) * | 1960-03-11 | 1962-11-06 | Lewis Howe Company | Antacid composition |
| US3215601A (en) * | 1963-02-07 | 1965-11-02 | Warner Lambert Pharmaceutical | Antacid composition and method of making same |
| US3361769A (en) * | 1964-01-22 | 1968-01-02 | Synergistics Inc | Bi-metallic salts of gluconic, glucuronic, or galacturonic acid |
| US3350266A (en) * | 1964-06-04 | 1967-10-31 | Bristol Myers Co | Antacid composition comprising aluminum hydroxide, magnesium hydroxide and magnesium gluconate |
-
1968
- 1968-04-05 US US719234A patent/US3621094A/en not_active Expired - Lifetime
-
1969
- 1969-03-19 AU AU52196/69A patent/AU443154B2/en not_active Expired
- 1969-03-20 IL IL31858A patent/IL31858A/en unknown
- 1969-03-21 IE IE374/69A patent/IE33016B1/en unknown
- 1969-03-27 DE DE1915798A patent/DE1915798C3/en not_active Expired
- 1969-03-31 FR FR6909622A patent/FR2005599A1/en active Granted
- 1969-04-01 GB GB17074/69A patent/GB1200157A/en not_active Expired
- 1969-04-02 NL NL6905135A patent/NL6905135A/xx unknown
- 1969-04-04 BE BE731060D patent/BE731060A/xx unknown
- 1969-04-04 LU LU58367D patent/LU58367A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE731060A (en) | 1969-10-06 |
| IL31858A0 (en) | 1969-05-28 |
| AU443154B2 (en) | 1973-11-28 |
| IL31858A (en) | 1972-05-30 |
| FR2005599B1 (en) | 1973-12-21 |
| NL6905135A (en) | 1969-10-07 |
| GB1200157A (en) | 1970-07-29 |
| US3621094A (en) | 1971-11-16 |
| LU58367A1 (en) | 1970-11-09 |
| FR2005599A1 (en) | 1969-12-12 |
| DE1915798C3 (en) | 1978-04-27 |
| AU5219669A (en) | 1970-09-24 |
| IE33016L (en) | 1969-10-05 |
| DE1915798A1 (en) | 1969-11-06 |
| DE1915798B2 (en) | 1977-08-25 |
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