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ID27035A - NEW SUBSTITUTED INDOLINONA, THEIR PRODUCTION AND USE AS A PHARMACY COMPOSITION - Google Patents

NEW SUBSTITUTED INDOLINONA, THEIR PRODUCTION AND USE AS A PHARMACY COMPOSITION

Info

Publication number
ID27035A
ID27035A IDW20002523A ID20002523A ID27035A ID 27035 A ID27035 A ID 27035A ID W20002523 A IDW20002523 A ID W20002523A ID 20002523 A ID20002523 A ID 20002523A ID 27035 A ID27035 A ID 27035A
Authority
ID
Indonesia
Prior art keywords
indolinona
production
new substituted
pharmacy composition
pharmacy
Prior art date
Application number
IDW20002523A
Other languages
Indonesian (id)
Inventor
Armin Dr Heckel
Rainer Dr Walter
Wolfgang Dr Grell
Jacobus C A Van Dr Meel
Norbert Dr Redemann
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ID27035A publication Critical patent/ID27035A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDW20002523A 1998-06-04 1999-05-28 NEW SUBSTITUTED INDOLINONA, THEIR PRODUCTION AND USE AS A PHARMACY COMPOSITION ID27035A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19824922A DE19824922A1 (en) 1998-06-04 1998-06-04 Novel substituted indolinones, their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
ID27035A true ID27035A (en) 2001-02-22

Family

ID=7869856

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002523A ID27035A (en) 1998-06-04 1999-05-28 NEW SUBSTITUTED INDOLINONA, THEIR PRODUCTION AND USE AS A PHARMACY COMPOSITION

Country Status (23)

Country Link
EP (1) EP1100779A1 (en)
JP (1) JP2002516906A (en)
KR (1) KR20010043973A (en)
CN (1) CN1303374A (en)
AU (1) AU764782B2 (en)
BG (1) BG104938A (en)
BR (1) BR9910898A (en)
CA (1) CA2328291A1 (en)
CO (1) CO5050294A1 (en)
DE (1) DE19824922A1 (en)
EA (1) EA003514B1 (en)
EE (1) EE200000723A (en)
HR (1) HRP20000831A2 (en)
HU (1) HUP0102210A3 (en)
ID (1) ID27035A (en)
IL (1) IL138702A0 (en)
NO (1) NO20006138L (en)
PL (1) PL344467A1 (en)
SK (1) SK18222000A3 (en)
TR (1) TR200003515T2 (en)
WO (1) WO1999062882A1 (en)
YU (1) YU73900A (en)
ZA (1) ZA200005435B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19816624A1 (en) * 1998-04-15 1999-10-21 Boehringer Ingelheim Pharma Novel substituted indolinones, their preparation and their use as pharmaceuticals
GB9904933D0 (en) 1999-03-04 1999-04-28 Glaxo Group Ltd Compounds
US6624171B1 (en) 1999-03-04 2003-09-23 Smithkline Beecham Corporation Substituted aza-oxindole derivatives
US6762180B1 (en) 1999-10-13 2004-07-13 Boehringer Ingelheim Pharma Kg Substituted indolines which inhibit receptor tyrosine kinases
UA75054C2 (en) * 1999-10-13 2006-03-15 Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг Substituted in position 6 indolinones, producing and use thereof as medicament
EP1339680A1 (en) 2000-09-01 2003-09-03 Glaxo Group Limited Substituted oxindole derivatives as tyrosine kinase inhibitors
AU8664701A (en) * 2000-09-01 2002-03-22 Glaxo Group Ltd Oxindole derivatives
DE10117204A1 (en) * 2001-04-06 2002-10-10 Boehringer Ingelheim Pharma Indolinones substituted in the 6-position, their preparation and their use as medicaments
US7727731B2 (en) 2001-06-29 2010-06-01 Ab Science Potent, selective and non toxic c-kit inhibitors
WO2003002106A2 (en) 2001-06-29 2003-01-09 Ab Science Use of tyrosine kinase inhibitions for treating allergic diseases
JP2004537537A (en) * 2001-06-29 2004-12-16 アブ サイエンス Uses of tyrosine kinase inhibitors to treat inflammatory diseases
DE60227709D1 (en) * 2001-06-29 2008-08-28 Ab Science THE USE OF C-CRITERIA FOR THE TREATMENT OF AUTOIMMUNE DISEASES
ATE343415T1 (en) * 2001-06-29 2006-11-15 Ab Science THE USE OF C-KIT INHIBITORS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
CA2461812C (en) 2001-09-27 2011-09-20 Allergan, Inc. 3-(arylamino)methylene-1,3-dihydro-2h-indol-2-ones as kinase inhibitors
US7169936B2 (en) 2002-07-23 2007-01-30 Boehringer Ingelheim Pharma Gmbh & Co. Kg Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments
JP4879492B2 (en) * 2002-11-27 2012-02-22 アラーガン、インコーポレイテッド Kinase inhibitors for the treatment of diseases
DE102004012070A1 (en) * 2004-03-12 2005-09-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg New cycloalkyl-containing 5-acylindolinones, their preparation and their use as medicaments
PE20060777A1 (en) * 2004-12-24 2006-10-06 Boehringer Ingelheim Int INDOLINONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES
ES2522587T3 (en) * 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Processes for preparing (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzacepin and intermediates thereof
GB0706072D0 (en) * 2007-03-28 2007-05-09 Sterix Ltd Compound
US20170065529A1 (en) 2015-09-09 2017-03-09 Boehringer Ingelheim International Gmbh Pharmaceutical dosage form for immediate release of an indolinone derivative
CN101735071A (en) * 2009-12-04 2010-06-16 大连凯飞精细化工有限公司 Method for producing 4-N,N-dimethylamino methylaniline
CN103102352B (en) * 2011-11-15 2015-08-12 山东亨利医药科技有限责任公司 Tyrosine kinase inhibitor indolinone derivative
CN103130775B (en) * 2011-11-22 2015-09-30 山东亨利医药科技有限责任公司 As the dihydroindole ketone derivate of tyrosine kinase inhibitor
GB201208775D0 (en) * 2012-05-18 2012-07-04 Uni I Oslo Chemical compounds
CN103848814B (en) * 2012-12-06 2016-08-17 山东亨利医药科技有限责任公司 The full ketone derivatives of substituted indole as tyrosine kinase inhibitor
KR20220008873A (en) 2019-05-10 2022-01-21 데시페라 파마슈티칼스, 엘엘씨. Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof
WO2024050297A1 (en) * 2022-09-02 2024-03-07 Deciphera Pharmaceuticals, Llc Ulk inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE838623A (en) * 1976-02-16 1976-06-16 3-HYDROXYMETHYLENE-2-INDOLINONE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
US4145422A (en) * 1977-09-06 1979-03-20 Abbott Laboratories Aminomethylene oxindoles
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
DE69734521T9 (en) * 1996-08-23 2006-12-07 Sugen, Inc., South San Francisco COMBINATIVE INDOLINO LIBRARIES AND RELATED PRODUCTS AND METHOD FOR THE TREATMENT OF DISEASES
GB9718913D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives

Also Published As

Publication number Publication date
TR200003515T2 (en) 2001-06-21
HUP0102210A2 (en) 2001-11-28
EE200000723A (en) 2002-04-15
JP2002516906A (en) 2002-06-11
BR9910898A (en) 2001-02-13
YU73900A (en) 2003-04-30
BG104938A (en) 2001-06-29
IL138702A0 (en) 2001-10-31
AU4370799A (en) 1999-12-20
EP1100779A1 (en) 2001-05-23
NO20006138D0 (en) 2000-12-01
EA200100001A1 (en) 2001-08-27
SK18222000A3 (en) 2001-08-06
PL344467A1 (en) 2001-11-05
CN1303374A (en) 2001-07-11
HRP20000831A2 (en) 2001-12-31
HUP0102210A3 (en) 2002-12-28
ZA200005435B (en) 2002-01-07
NO20006138L (en) 2001-02-01
KR20010043973A (en) 2001-05-25
WO1999062882A1 (en) 1999-12-09
DE19824922A1 (en) 1999-12-09
EA003514B1 (en) 2003-06-26
CO5050294A1 (en) 2001-06-27
CA2328291A1 (en) 1999-12-09
AU764782B2 (en) 2003-08-28

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