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ID24054A - Turunan turunan benzimidazol - Google Patents

Turunan turunan benzimidazol

Info

Publication number
ID24054A
ID24054A IDW20000038A ID20000038A ID24054A ID 24054 A ID24054 A ID 24054A ID W20000038 A IDW20000038 A ID W20000038A ID 20000038 A ID20000038 A ID 20000038A ID 24054 A ID24054 A ID 24054A
Authority
ID
Indonesia
Prior art keywords
benzimidazol
benzimidazol down
Prior art date
Application number
IDW20000038A
Other languages
English (en)
Indonesian (id)
Inventor
John Charlas Drach
Leroy B Townsend
Frank Leslie Boyd Jr
Stanley Dawes Chamberlain
Susan Mary Daluge
David Norman Daeton
Marc W Andersen
George Andrew Freeman
Original Assignee
Glaxo Group Ltd Glaxo
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9711982.0A external-priority patent/GB9711982D0/en
Priority claimed from GBGB9714552.8A external-priority patent/GB9714552D0/en
Application filed by Glaxo Group Ltd Glaxo, Univ Michigan filed Critical Glaxo Group Ltd Glaxo
Publication of ID24054A publication Critical patent/ID24054A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
IDW20000038A 1997-06-10 1998-06-08 Turunan turunan benzimidazol ID24054A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711982.0A GB9711982D0 (en) 1997-06-10 1997-06-10 Benzimidazole derivatives
GBGB9714552.8A GB9714552D0 (en) 1997-07-11 1997-07-11 Benzimidazole derivatives

Publications (1)

Publication Number Publication Date
ID24054A true ID24054A (id) 2000-07-06

Family

ID=26311687

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000038A ID24054A (id) 1997-06-10 1998-06-08 Turunan turunan benzimidazol

Country Status (34)

Country Link
US (1) US6455507B1 (es)
EP (1) EP0994890B1 (es)
JP (1) JP4548866B2 (es)
KR (1) KR20010020465A (es)
CN (1) CN1265665A (es)
AP (1) AP1262A (es)
AR (1) AR012964A1 (es)
AT (1) ATE246700T1 (es)
AU (1) AU740792C (es)
BR (1) BR9810745A (es)
CA (1) CA2293470C (es)
CO (1) CO4970737A1 (es)
DE (1) DE69816992T2 (es)
DK (1) DK0994890T3 (es)
EA (1) EA002305B1 (es)
EE (1) EE9900564A (es)
ES (1) ES2205527T3 (es)
HR (1) HRP980303B1 (es)
HU (1) HUP0002224A3 (es)
ID (1) ID24054A (es)
IL (1) IL133285A0 (es)
IS (1) IS5285A (es)
MA (1) MA26504A1 (es)
MY (1) MY132872A (es)
NO (1) NO314847B1 (es)
NZ (1) NZ501415A (es)
OA (1) OA11230A (es)
PE (1) PE84099A1 (es)
PL (1) PL337773A1 (es)
PT (1) PT994890E (es)
SK (1) SK171499A3 (es)
TR (1) TR199903053T2 (es)
TW (1) TW565566B (es)
WO (1) WO1998056761A2 (es)

Families Citing this family (42)

* Cited by examiner, ā€  Cited by third party
Publication number Priority date Publication date Assignee Title
AU1702597A (en) 1996-01-23 1997-08-20 Glaxo Group Limited Modified benzimidazole nucleosides as antiviral agents
US6455506B1 (en) 1997-07-30 2002-09-24 Smithkline Beecham Corporation Lyxofuranosyl benzimidazoles as antiviral agents
DE19741715A1 (de) * 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
GB0008939D0 (en) 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
ES2291455T3 (es) 2001-03-12 2008-03-01 Avanir Pharmaceuticals Compuestos de bencimidazol para modular ige e inhibir la proliferacion celular.
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AR048377A1 (es) * 2003-08-01 2006-04-26 Janssen Pharmaceutica Nv Benzoimidazol-, benzotriazol- y benzoimidazolona - o- glucosidos sustituidos
US20110070192A1 (en) * 2003-11-14 2011-03-24 Bruno Tse Method of preparation of novel nucleoside analogs and uses
CA2752738C (en) * 2005-02-22 2014-05-27 The Regents Of The University Of Michigan Small molecule inhibitors of mdm2 and uses thereof
DE102005019549A1 (de) * 2005-04-25 2006-12-14 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Diaminobenzimidazol
EP1962864A4 (en) * 2005-12-22 2010-02-17 Alchemia Ltd ANTIBACTERIAL AGENTS
US7951845B2 (en) 2006-01-19 2011-05-31 The Regents Of The University Of Michigan Composition and method of treating hearing loss
US8338397B2 (en) 2006-01-19 2012-12-25 The Regents Of The University Of Michigan Composition and method of treating side effects from antibiotic treatment
US10238599B2 (en) 2006-01-19 2019-03-26 The Regents Of The University Of Michigan Composition and method for treating congenital cytomegalovirus induced hearing loss
US8927528B2 (en) 2006-01-19 2015-01-06 The Regents Of The University Of Michigan Composition for treating hearing loss
US9919008B2 (en) 2006-01-19 2018-03-20 The Regents Of The University Of Michigan Method for treating age-related hearing loss (ARHL)
US9770433B2 (en) 2006-01-19 2017-09-26 The Regents Of The University Of Michigan Composition and method for treating tinnitus
USRE46372E1 (en) 2006-01-19 2017-04-25 The Regents Of The Univerity Of Michigan Method for treating hearing loss
US9889156B2 (en) 2006-01-19 2018-02-13 The Regents Of The University Of Michigan Method for treating noise-induced hearing loss (NIHL)
AU2008286771B2 (en) 2007-08-15 2013-08-15 Isis Pharmaceuticals, Inc. Tetrahydropyran nucleic acid analogs
US8987468B2 (en) * 2008-02-04 2015-03-24 The Translational Genomics Research Institute Compounds, pharmaceutical compositions and methods of use of hydroxamic acid derivatives
EP2265627A2 (en) 2008-02-07 2010-12-29 Isis Pharmaceuticals, Inc. Bicyclic cyclohexitol nucleic acid analogs
WO2010036613A1 (en) 2008-09-26 2010-04-01 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
CA2741125A1 (en) 2008-10-22 2010-04-29 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
EP2352374B1 (en) 2008-10-29 2014-09-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
WO2010051206A1 (en) 2008-10-31 2010-05-06 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
US8536320B2 (en) 2009-02-06 2013-09-17 Isis Pharmaceuticals, Inc. Tetrahydropyran nucleic acid analogs
WO2010091308A2 (en) 2009-02-06 2010-08-12 Isis Pharmaceuticals, Inc. Oligomeric compounds and methods
US8895596B2 (en) 2010-02-25 2014-11-25 Merck Sharp & Dohme Corp Cyclic benzimidazole derivatives useful as anti-diabetic agents
EP2601204B1 (en) 2010-04-28 2016-09-07 Ionis Pharmaceuticals, Inc. Modified nucleosides and oligomeric compounds prepared therefrom
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-Ī²-L-ribofuranosyl)-1H-benzimidazole
WO2014134493A1 (en) * 2013-03-01 2014-09-04 Los Alamos National Security, Llc Broad spectrum antibiotic compounds and use thereof
EP3137476B1 (en) 2014-04-28 2019-10-09 Ionis Pharmaceuticals, Inc. Linkage modified oligomeric compounds
WO2016089845A1 (en) * 2014-12-01 2016-06-09 Virginia Commonwealth University A convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction
RU2629670C2 (ru) * 2016-08-04 2017-08-31 Š¤ŠµŠ“ŠµŃ€Š°Š»ŃŒŠ½Š¾Šµ Š³Š¾ŃŃƒŠ“Š°Ń€ŃŃ‚Š²ŠµŠ½Š½Š¾Šµ Š±ŃŽŠ“Š¶ŠµŃ‚Š½Š¾Šµ учрŠµŠ¶Š“ŠµŠ½ŠøŠµ Š½Š°ŃƒŠŗŠø ŠøŠ½ŃŃ‚Šøтут Š±ŠøŠ¾Š¾Ń€Š³Š°Š½ŠøчŠµŃŠŗŠ¾Š¹ хŠøŠ¼ŠøŠø ŠøŠ¼. Š°ŠŗŠ°Š“ŠµŠ¼ŠøŠŗŠ¾Š² Šœ.Šœ. ŠØŠµŠ¼ŃŠŗŠøŠ½Š° Šø Š®.Š. ŠžŠ²Ń‡ŠøŠ½Š½ŠøŠŗŠ¾Š²Š° Š Š¾ŃŃŠøŠ¹ŃŠŗŠ¾Š¹ Š°ŠŗŠ°Š“ŠµŠ¼ŠøŠø Š½Š°ŃƒŠŗ (Š˜Š‘Š„ Š ŠŠ) 2-ŠŠ¼ŠøŠ½Š¾-5,6-Š“ŠøфтŠ¾Ń€-1-(Š±ŠµŃ‚Š°-D-рŠøŠ±Š¾Ń„ŃƒŃ€Š°Š½Š¾Š·ŠøŠ»)-Š±ŠµŠ½Š·ŠøŠ¼ŠøŠ“Š°Š·Š¾Š», сŠæŠ¾ŃŠ¾Š± ŠæŠ¾Š»ŃƒŃ‡ŠµŠ½Šøя Šø ŠæрŠ¾Ń‚ŠøŠ²Š¾Š²ŠøрусŠ½Š°Ń Š°ŠŗтŠøŠ²Š½Š¾ŃŃ‚ŃŒ ŠµŠ³Š¾ Š² Š¾Ń‚Š½Š¾ŃˆŠµŠ½ŠøŠø Š²ŠøрусŠ° Š³ŠµŃ€ŠæŠµŃŠ° ŠæрŠ¾ŃŃ‚Š¾Š³Š¾ 1-Š³Š¾ тŠøŠæŠ°
KR102583547B1 (ko) 2020-03-30 2023-10-06 (ģ£¼)ė°”ģ“ģ˜¤ė©”ķŠøė¦­ģŠ¤ ķ…Œķ¬ė†€ė”œģ§€ ģ‹ ź·œķ•œ ė²¤ģ§€ėÆøė‹¤ģ”ø ģœ ė„ģ²“, ģ“ģ˜ ģ œģ”°ė°©ė²• ė° ģ“ģ˜ ķ•­ģ•”ģ œ ģš©ė„
EP3907230B1 (en) * 2020-03-30 2024-08-28 Biometrix Technology Inc. Novel benzimidazole derivatives, preparation method thereof and use thereof as anti-cancer agent comprising the same
US12043644B2 (en) 2020-06-23 2024-07-23 Biometrix Technology Inc Benzimidazole derivatives, preparation method thereof and use thereof as anti-cancer agent or anti-virus agent comprising the same
KR102449266B1 (ko) 2020-06-23 2022-09-30 (ģ£¼)ė°”ģ“ģ˜¤ė©”ķŠøė¦­ģŠ¤ ķ…Œķ¬ė†€ė”œģ§€ ķ•­ģ•” ķ™œģ„± ź·øė¦¬ź³  ķ•­ė°”ģ“ėŸ¬ģŠ¤ ķ™œģ„±ģ„ ź°–ėŠ” ģ‹ ź·œķ•œ ė²¤ģ§€ėÆøė‹¤ģ”ø-ķƒ„ģˆ˜ķ™”ė¬¼ ź²°ķ•©ģ²“ ķ™”ķ•©ė¬¼(Benzimidazole carbohydrate conjugate compound) ė° ģ“ģ˜ ģ œģ”° ė°©ė²•
KR102342313B1 (ko) 2021-08-27 2021-12-24 (ģ£¼)ė°”ģ“ģ˜¤ė©”ķŠøė¦­ģŠ¤ ķ…Œķ¬ė†€ė”œģ§€ ė²¤ģ§€ėÆøė‹¤ģ”ø-ķƒ„ģˆ˜ķ™”ė¬¼ ź²°ķ•©ģ²“ ķ™”ķ•©ė¬¼ģ„ ķ¬ķ•Øķ•˜ėŠ” ėÆøģ…€, ģ“ģ˜ ģ œģ”°ė°©ė²•, ģ“ģ˜ ķ•­ģ•”ģ œ ė˜ėŠ” ķ•­ė°”ģ“ėŸ¬ģŠ¤ģ œė”œģ„œģ˜ ģš©ė„
CN119119151A (zh) * 2024-09-04 2024-12-13 ę–Æ坦德čÆå…øę ‡å‡†ē‰©č“Øē ”发(ę¹–åŒ—)ęœ‰é™å…¬åø äø€ē§é©¬ē«‹å·“韦ēš„åˆ¶å¤‡ę–¹ę³•

Family Cites Families (14)

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FR1491244A (fr) 1966-03-09 1967-08-11 Nouveaux benzimidazoles solubles
FR1476350A (fr) 1966-04-18 1967-04-07 Yale & Towne G M B H Ferme-porte automatique Ć  frein
US3655901A (en) 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
DE2130030A1 (de) 1971-06-18 1972-12-21 Bayer Ag Fungizide und bakterizide Mittel
ES482789A0 (es) 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
DK405988A (da) 1987-07-29 1989-01-30 Hoffmann La Roche Benzimidazolderivater
IT1226100B (it) 1988-07-07 1990-12-10 Dompe Farmaceutici Spa Derivati benzimidazolici farmacologicamente attivi.
US5248672A (en) 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
ZA923641B (en) 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
EP0521463A3 (en) 1991-07-04 1993-04-14 Hoechst Aktiengesellschaft Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents
GB9205071D0 (en) 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
WO1994008456A1 (en) 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
US5399580A (en) 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides

Also Published As

Publication number Publication date
CA2293470A1 (en) 1998-12-17
KR20010020465A (ko) 2001-03-15
HRP980303B1 (en) 2002-08-31
PE84099A1 (es) 1999-09-24
AP1262A (en) 2004-03-16
AU740792C (en) 2003-01-23
MY132872A (en) 2007-10-31
EA199901031A1 (ru) 2000-06-26
EE9900564A (et) 2000-06-15
HK1024921A1 (en) 2000-10-27
ES2205527T3 (es) 2004-05-01
NO996086L (no) 2000-02-09
PL337773A1 (en) 2000-09-11
PT994890E (pt) 2003-11-28
IL133285A0 (en) 2001-04-30
OA11230A (en) 2003-07-09
JP2002504105A (ja) 2002-02-05
HUP0002224A3 (en) 2003-05-28
SK171499A3 (en) 2000-08-14
EA002305B1 (ru) 2002-02-28
WO1998056761A2 (en) 1998-12-17
BR9810745A (pt) 2001-03-13
NZ501415A (en) 2001-10-26
AP9901707A0 (en) 1999-12-31
HRP980303A2 (en) 1999-04-30
JP4548866B2 (ja) 2010-09-22
DE69816992T2 (de) 2004-07-22
DK0994890T3 (da) 2003-12-01
NO314847B1 (no) 2003-06-02
EP0994890A2 (en) 2000-04-26
CO4970737A1 (es) 2000-11-07
US6455507B1 (en) 2002-09-24
ATE246700T1 (de) 2003-08-15
IS5285A (is) 1999-12-06
TW565566B (en) 2003-12-11
EP0994890B1 (en) 2003-08-06
MA26504A1 (fr) 2004-12-20
US20020094963A1 (en) 2002-07-18
AU740792B2 (en) 2001-11-15
DE69816992D1 (en) 2003-09-11
AR012964A1 (es) 2000-11-22
NO996086D0 (no) 1999-12-09
WO1998056761A3 (en) 1999-04-15
CN1265665A (zh) 2000-09-06
TR199903053T2 (xx) 2000-11-21
HUP0002224A1 (hu) 2001-04-28
CA2293470C (en) 2008-05-13
AU8536098A (en) 1998-12-30

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