[go: up one dir, main page]

ID23803A - Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola - Google Patents

Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola

Info

Publication number
ID23803A
ID23803A IDW20000197A ID20000197A ID23803A ID 23803 A ID23803 A ID 23803A ID W20000197 A IDW20000197 A ID W20000197A ID 20000197 A ID20000197 A ID 20000197A ID 23803 A ID23803 A ID 23803A
Authority
ID
Indonesia
Prior art keywords
durunan
indola
ilmetil
heteroaril
aril
Prior art date
Application number
IDW20000197A
Other languages
English (en)
Inventor
Anton Franz Josef Fliri
Mark Jerome Majchrzak
Patricia Ann Seymour
Stevin Howard Zorn
Hans Rollema
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ID23803A publication Critical patent/ID23803A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IDW20000197A 1997-08-15 1998-08-05 Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola ID23803A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5576497P 1997-08-15 1997-08-15

Publications (1)

Publication Number Publication Date
ID23803A true ID23803A (id) 2000-05-11

Family

ID=22000003

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000197A ID23803A (id) 1997-08-15 1998-08-05 Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola

Country Status (30)

Country Link
EP (1) EP1003739A2 (id)
JP (1) JP2002536291A (id)
KR (1) KR20010022507A (id)
CN (1) CN1265660A (id)
AP (1) AP9801321A0 (id)
AR (1) AR017019A1 (id)
AU (1) AU8457298A (id)
BG (1) BG104069A (id)
BR (1) BR9811557A (id)
CA (1) CA2297486C (id)
CO (1) CO4960656A1 (id)
DZ (1) DZ2583A1 (id)
EA (1) EA200000023A1 (id)
HR (1) HRP980441A2 (id)
HU (1) HUP0003425A3 (id)
ID (1) ID23803A (id)
IL (1) IL133960A0 (id)
IS (1) IS5336A (id)
MA (1) MA24632A1 (id)
NO (1) NO20000722D0 (id)
OA (1) OA11286A (id)
PA (1) PA8457001A1 (id)
PE (1) PE106299A1 (id)
PL (1) PL338947A1 (id)
SK (1) SK1352000A3 (id)
TN (1) TNSN98151A1 (id)
TR (1) TR200000414T2 (id)
UY (1) UY25144A1 (id)
WO (1) WO1999009025A2 (id)
ZA (1) ZA987304B (id)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4570773B2 (ja) * 1997-10-27 2010-10-27 ニューロサーチ、アクティーゼルスカブ ニコチン性アセチルコリンレセプターに於けるコリン作動性リガンドとしてのヘテロアリールジアザシクロアルカン
EP0953567A3 (en) 1998-04-29 2003-04-02 Pfizer Products Inc. Bicyclic substituted piperazine-, piperidine- and tetrahydropyridine derivatives, their preparation and their use as agents with central dopaminergic (dopamine D4 receptor) activity
EA008627B1 (ru) 1999-12-30 2007-06-29 Х. Лундбекк А/С Замещенные галогеном производные 4-фенил-1-пиперазинила, их применение и содержащая их фармацевтическая композиция
GB0017952D0 (en) * 2000-07-22 2000-09-13 Univ Manchester Treatment of dyskinesia
EP1177792A3 (en) 2000-07-27 2002-10-23 Pfizer Products Inc. Dopamine D4 Ligands for the treatment of novelty-seeking disorders
EP1373204B1 (en) 2001-03-09 2016-10-26 Janssen Pharmaceuticals, Inc. Heterocyclic compounds
AU2003265886A1 (en) 2002-09-06 2004-03-29 Janssen Pharmaceutica N.V. (1H-Benzoimidazol-2-yl)-(piperazinyl)-methanone derivatives and related compounds as histamine H4-receptor antagonists for the treatment of inflammatory and allergic disorders
WO2004108671A1 (en) * 2003-06-06 2004-12-16 Suven Life Sciences Limited Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them
JP4859665B2 (ja) 2004-03-30 2012-01-25 武田薬品工業株式会社 アルコキシフェニルプロパン酸誘導体
US7618980B2 (en) 2004-07-14 2009-11-17 Bristol-Myers Squibb Company Pyrrolo(oxo)quinolines as 5HT ligands
US7572805B2 (en) 2004-07-14 2009-08-11 Bristol-Myers Squibb Company Pyrrolo(oxo)isoquinolines as 5HT ligands
JO2769B1 (en) * 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
KR101506156B1 (ko) 2007-04-23 2015-03-26 얀센 파마슈티카 엔.브이. 속해리성 도파민 2 수용체 길항제로서의 티아(디아)졸
RS52518B (en) 2007-04-23 2013-04-30 Janssen Pharmaceutica N.V. 4-ALCOXYPYRIDASINE DERIVATIVES AS A FAST DISSOCATING DOPAMINE 2 RECEPTOR ANTAGONISTS
ES2398625T3 (es) 2008-07-03 2013-03-20 Janssen Pharmaceutica N.V. 6-(1-Piperazinil)-piritazinas sustituidas como antagonistas de receptores 5-HT6
EP2307374B1 (en) 2008-07-31 2017-01-25 Janssen Pharmaceutica NV Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists
WO2019057123A1 (zh) * 2017-09-20 2019-03-28 杭州英创医药科技有限公司 作为ido抑制剂和/或ido-hdac双重抑制剂的多环化合物
JP2023523176A (ja) * 2020-04-22 2023-06-02 アニマ バイオテック インコーポレイテッド コラーゲン１翻訳阻害剤及びその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB944443A (id) * 1959-09-25 1900-01-01
ES2097341T3 (es) * 1991-07-03 1997-04-01 Upjohn Co Indoles sustituidos como farmacos para el tratamiento del sida.
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
WO1994010162A1 (en) * 1992-10-23 1994-05-11 Merck Sharp & Dohme Limited Dopamine receptor subtype ligands
US5576336A (en) * 1993-03-18 1996-11-19 Merck Sharp & Dohme Limited Indole derivatives as dopamine D4 antagonists
GB9305644D0 (en) * 1993-03-18 1993-05-05 Merck Sharp & Dohme Therapeutic agents
WO1994024105A1 (en) * 1993-04-15 1994-10-27 Merck Sharp & Dohme Limited Indole derivatives as dopamine d4 antagonists
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
TW406075B (en) * 1994-12-13 2000-09-21 Upjohn Co Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
TW504510B (en) * 1996-05-10 2002-10-01 Janssen Pharmaceutica Nv 2,4-diaminopyrimidine derivatives

Also Published As

Publication number Publication date
IS5336A (is) 2000-01-11
CN1265660A (zh) 2000-09-06
ZA987304B (en) 2000-02-14
CA2297486C (en) 2005-05-03
PA8457001A1 (es) 2000-09-29
HUP0003425A3 (en) 2002-02-28
AR017019A1 (es) 2001-08-22
UY25144A1 (es) 2000-12-29
WO1999009025A3 (en) 1999-04-15
SK1352000A3 (en) 2000-08-14
WO1999009025A2 (en) 1999-02-25
AU8457298A (en) 1999-03-08
AP9801321A0 (en) 2000-02-14
HUP0003425A2 (hu) 2001-10-28
BG104069A (en) 2001-05-31
IL133960A0 (en) 2001-04-30
CO4960656A1 (es) 2000-09-25
KR20010022507A (ko) 2001-03-15
EP1003739A2 (en) 2000-05-31
PL338947A1 (en) 2000-12-04
MA24632A1 (fr) 1999-04-01
JP2002536291A (ja) 2002-10-29
BR9811557A (pt) 2000-08-22
CA2297486A1 (en) 1999-02-25
EA200000023A1 (ru) 2000-08-28
NO20000722L (no) 2000-02-14
TR200000414T2 (tr) 2000-08-21
DZ2583A1 (fr) 2003-02-22
TNSN98151A1 (fr) 2005-03-15
PE106299A1 (es) 1999-11-02
HRP980441A2 (en) 1999-04-30
OA11286A (en) 2003-10-22
NO20000722D0 (no) 2000-02-14

Similar Documents

Publication Publication Date Title
ID17053A (id) Derivat-derivat 2-(2-okso-etiliden)-imidazolidin-4-on
PT973746E (pt) 3-ciano-quinolinas substituidas
ATA93198A (de) Fluoxetinpellets
MX209959B (es) 4-(3-heterociclil-1-benzoil)pirazoles
ID23173A (id) Turunan pirol trisiklik atau pirazol
ID23803A (id) Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola
DE59813487D1 (de) Substituierte 4-benzoyl-pyrazole
ATA111897A (de) Kimme
BR9801805A (pt) Dioxacicloalcan-8-ona
ATE236897T1 (de) 3-benzylpiperidine
ATA112597A (de) Snowboard - bindung
DK0960100T3 (da) Substituerede 4-benzoyl-pyrazoler
DE59807877D1 (de) Substituierte 4-benzoyl-pyrazole
ID24079A (id) Aminoheteroksiklilamida tersubstitusi
ATA86797A (de) Verschleissschuh
ID20883A (id) Turunan-turunan 2-(arilfenil) amino-imidazolina
DE59810960D1 (de) Substituierte phenyluracile
ATA46498A (de) Kunststoffgleitbahn
BR9701194A (pt) Hidrociclo
ATE266645T1 (de) Substituierte phenyluracile
ATE421585T1 (de) Motlinhomologe
BR7700737U (pt) Tarraxa
BR9701098A (pt) Acerbol
BR7700917U (pt) Microintercomunicador-comunicador
BR7701838U (pt) Monotocentrociclo