ID22275A - PHARMACEUTICAL COMPOSITION CONSIST OF AMINO N-ACID (ARIL OR HETEROARIL) DERIVATES AND METHODS TO RESPOND TO B-AMILOID RELEASE PEPTIDES AND OR SYNTHESIS USING SUCH COMPOUNDS. - Google Patents

PHARMACEUTICAL COMPOSITION CONSIST OF AMINO N-ACID (ARIL OR HETEROARIL) DERIVATES AND METHODS TO RESPOND TO B-AMILOID RELEASE PEPTIDES AND OR SYNTHESIS USING SUCH COMPOUNDS.

Info

Publication number: ID22275A
Authority: ID; Indonesia
Prior art keywords: amiloid; heteroaril; aril; derivates; respond
Prior art date: 1996-11-22

Application number

IDW990395A

Other languages

Indonesian (id)

Inventor

James E Audia

Beverly K Polmer

Varghese John

Lee H Latimer

Jeffrey S Nissen

Warren J Porter

Eugene D Thorsett

Jing Wu

Original Assignee

Elan Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-22

Filing date

1997-11-20

Publication date

1999-09-23

1997-11-20 Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc

1999-09-23 Publication of ID22275A publication Critical patent/ID22275A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IDW990395A 1996-11-22 1997-11-20 PHARMACEUTICAL COMPOSITION CONSIST OF AMINO N-ACID (ARIL OR HETEROARIL) DERIVATES AND METHODS TO RESPOND TO B-AMILOID RELEASE PEPTIDES AND OR SYNTHESIS USING SUCH COMPOUNDS. ID22275A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US75533496A	1996-11-22	1996-11-22

Publications (1)

Publication Number	Publication Date
ID22275A true ID22275A (en)	1999-09-23

Family

ID=25038718

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW990395A ID22275A (en)	1996-11-22	1997-11-20	PHARMACEUTICAL COMPOSITION CONSIST OF AMINO N-ACID (ARIL OR HETEROARIL) DERIVATES AND METHODS TO RESPOND TO B-AMILOID RELEASE PEPTIDES AND OR SYNTHESIS USING SUCH COMPOUNDS.

Country Status (13)

Country	Link
EP (1)	EP0942923A2 (en)
JP (1)	JP2001519769A (en)
CN (1)	CN1237978A (en)
AU (1)	AU5354398A (en)
BR (1)	BR9714358A (en)
CA (1)	CA2270876A1 (en)
HU (1)	HUP0001383A3 (en)
ID (1)	ID22275A (en)
IL (1)	IL129477A0 (en)
NO (1)	NO992426L (en)
NZ (1)	NZ335157A (en)
TR (1)	TR199901132T2 (en)
WO (1)	WO1998022493A2 (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP990246A2 (en)	1998-08-07	2000-06-30	Du Pont Pharm Co	Succinoylamino benzodiazepines as inhibitors of a beta protein production
NZ525513A (en)	1998-08-07	2004-09-24	Pont Pharmaceuticals Du	Succinoylamino lactams as inhibitors of Abeta protein production
JP2003524601A (en)	1998-09-30	2003-08-19	エランファーマシューティカルズ，インコーポレイテッド	Biological reagents and methods for determining the mechanism of β-amyloid peptide production
US6737038B1 (en)	1998-11-12	2004-05-18	Bristol-Myers Squibb Company	Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
CA2347671A1 (en)	1998-12-24	2000-07-06	Dupont Pharmaceuticals Company	Succinoylamino benzodiazepines as inhibitors of a.beta. protein production
US6960576B2 (en)	1999-09-13	2005-11-01	Bristol-Myers Squibb Pharma Company	Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
US6503902B2 (en)	1999-09-13	2003-01-07	Bristol-Myers Squibb Pharma Company	Hydroxyalkanoylaminolactams and related structures as inhibitors of a β protein production
EP1222176A1 (en)	1999-10-08	2002-07-17	Bristol-Myers Squibb Pharma Company	AMINO LACTAM SULFONAMIDES AS INHIBITORS OF A$g(b) PROTEIN PRODUCTION
EP1261610A2 (en)	2000-02-17	2002-12-04	Bristol-Myers Squibb Pharma Company	Succinoylamino carbocycles and heterocycles as inhibitors of a-beta protein production
AU2001253090A1 (en)	2000-04-03	2001-10-15	Bristol-Myers Squibb Pharma Company	Cyclic lactams as inhibitors of abeta protein production
CN1434803A (en)	2000-04-03	2003-08-06	布里斯托尔-迈尔斯斯奎布药品公司	Cyclic lactams as inhibitors os A-alpha protein production
US6632812B2 (en)	2000-04-11	2003-10-14	Dupont Pharmaceuticals Company	Substituted lactams as inhibitors of Aβ protein production
US6878363B2 (en)	2000-05-17	2005-04-12	Bristol-Myers Squibb Pharma Company	Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
AU783857B2 (en)	2000-06-01	2005-12-15	Bristol-Myers Squibb Pharma Company	Lactams substituted by cyclic succinates as inhibitors of a beta protein production
US6432944B1 (en)	2000-07-06	2002-08-13	Bristol-Myers Squibb Company	Benzodiazepinone β-amyloid inhibitors: arylacetamidoalanyl derivatives
HU230375B1 (en)	2000-08-24	2016-03-29	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Thioflavin derivatives and their use in diagnosis and treatment of alzheimer's disease
US7270800B2 (en)	2000-08-24	2007-09-18	University Of Pittsburgh	Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US6657070B2 (en)	2000-12-13	2003-12-02	Wyeth	Production of chirally pure α-amino acids and N-sulfonyl α-amino acids
CA2436526C (en)	2000-12-13	2010-10-19	Wyeth	Heterocyclic sulfonamide inhibitors of beta amyloid production
CH698246B1 (en) *	2001-12-20	2009-06-30	Hoffmann La Roche	Test to identify inhibitors of beta secretases.
DE10306202A1 (en) *	2003-02-13	2004-08-26	Grünenthal GmbH	2-(hetero)aryl-2-(N-((hetero)aryl)-amino)-acetic acid derivatives useful e.g. for treating anxiety, inflammation, allergy, depression, diarrhea or especially pain is NMDA antagonist
PT1611115E (en) *	2003-03-14	2012-12-07	Univ Pittsburgh	Benzothiazole derivative compounds, compositions and uses
AR043940A1 (en)	2003-03-31	2005-08-17	Wyeth Corp	INHIBITORS OF HETEROCICLIC SULFONAMIDS CONTAINING FLUOR- AND TRIFLUORALQUILO OF THE PRODUCTION OF BETA AMILOIDES AND DERIVATIVES OF THE SAME
CA2528496C (en)	2003-06-05	2011-04-12	Elan Pharmaceuticals, Inc.	Acylated amino acid amidyl pyrazoles and related compounds
US8236282B2 (en)	2003-08-22	2012-08-07	University of Pittsburgh—of the Commonwealth System of Higher Education	Benzothiazole derivative compounds, compositions and uses
US7399778B2 (en)	2004-01-16	2008-07-15	Wyeth	Heterocyclic sulfonamide inhibitors of beta amyloid production containing an azole
EP1725522B1 (en)	2004-03-03	2014-09-10	GlaxoSmithKline LLC	Aniline derivatives as selective androgen receptor modulators
US20080194536A1 (en) *	2005-04-15	2008-08-14	Marlys Hammond	Cyanoarylamines
CN100999546B (en) *	2007-01-11	2010-08-11	清华大学	Polypeptide compound with aza-containing heterocyclic modification and its application
WO2012172449A1 (en)	2011-06-13	2012-12-20	Pfizer Inc.	Lactams as beta secretase inhibitors
CN111777571B (en) *	2020-06-28	2023-07-11	武汉药明康德新药开发有限公司	Synthesis method of chiral 2-amino-3- (1, 3-benzothiazole-2-yl) propionic acid hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0721449T3 (en) *	1993-10-01	2002-04-22	Merrell Pharma Inc	Inhibitors of beta-amyloid protein production
US5872101A (en) *	1995-01-06	1999-02-16	Sibia Neurosciences, Inc.	Methods of treating neurodegenerative disorders using protease inhibitors

1997
- 1997-11-20 ID IDW990395A patent/ID22275A/en unknown
- 1997-11-20 AU AU53543/98A patent/AU5354398A/en not_active Abandoned
- 1997-11-20 NZ NZ335157A patent/NZ335157A/en unknown
- 1997-11-20 HU HU0001383A patent/HUP0001383A3/en unknown
- 1997-11-20 IL IL12947797A patent/IL129477A0/en unknown
- 1997-11-20 TR TR1999/01132T patent/TR199901132T2/en unknown
- 1997-11-20 EP EP97950576A patent/EP0942923A2/en not_active Withdrawn
- 1997-11-20 WO PCT/US1997/018704 patent/WO1998022493A2/en not_active Application Discontinuation
- 1997-11-20 JP JP52364998A patent/JP2001519769A/en active Pending
- 1997-11-20 CN CN97199776A patent/CN1237978A/en active Pending
- 1997-11-20 CA CA002270876A patent/CA2270876A1/en not_active Abandoned
- 1997-11-20 BR BR9714358A patent/BR9714358A/en not_active IP Right Cessation
1999
- 1999-05-20 NO NO992426A patent/NO992426L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0942923A2 (en)	1999-09-22
NO992426L (en)	1999-06-30
HUP0001383A1 (en)	2001-05-28
JP2001519769A (en)	2001-10-23
NO992426D0 (en)	1999-05-20
IL129477A0 (en)	2000-02-29
TR199901132T2 (en)	1999-08-23
CA2270876A1 (en)	1998-05-28
NZ335157A (en)	2001-01-26
BR9714358A (en)	2000-03-21
CN1237978A (en)	1999-12-08
WO1998022493A2 (en)	1998-05-28
AU5354398A (en)	1998-06-10
WO1998022493A3 (en)	1998-07-23
HUP0001383A3 (en)	2001-11-28

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