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HUT50817A - Process for producing substituted-1,2,4-triazolo/4,3-a/ pyridin-3/2h/-one and salts thereof - Google Patents

Process for producing substituted-1,2,4-triazolo/4,3-a/ pyridin-3/2h/-one and salts thereof

Info

Publication number
HUT50817A
HUT50817A HU402888A HU402888A HUT50817A HU T50817 A HUT50817 A HU T50817A HU 402888 A HU402888 A HU 402888A HU 402888 A HU402888 A HU 402888A HU T50817 A HUT50817 A HU T50817A
Authority
HU
Hungary
Prior art keywords
triazolo
general formula
pyridin
salts
pyridine
Prior art date
Application number
HU402888A
Other languages
Hungarian (hu)
Other versions
HU201324B (en
Inventor
Zoltan Budai
Tibor Mezei
Jozsefne Reiter
Laszlone Lax
Belane Somogyi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU402888A priority Critical patent/HU201324B/en
Publication of HUT50817A publication Critical patent/HUT50817A/en
Publication of HU201324B publication Critical patent/HU201324B/en

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pure substd. 1,2,4-triazolo- (4,3-a)-pyridine-3(2H)-one of general formula (I) a known antidepressant is prepd. by a novel method and at high yields in a dipolar aprotic solvent from 1,2,4-tri:azolo-(4,3-a)-pyridine -3(2H)-one of general formula (II) and 1-(3'-chloro-propyl)-4-(m-chlorophenyl- piperazine-hydrochloride of general formula (III) in the presence of an alkali-carbonate or powdered sodium-hydroxide condensing agent. The resulting base (I) is opt. - converted to a corresponding salt.
HU402888A 1988-07-29 1988-07-29 New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on HU201324B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU402888A HU201324B (en) 1988-07-29 1988-07-29 New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU402888A HU201324B (en) 1988-07-29 1988-07-29 New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on

Publications (2)

Publication Number Publication Date
HUT50817A true HUT50817A (en) 1990-03-28
HU201324B HU201324B (en) 1990-10-28

Family

ID=10966598

Family Applications (1)

Application Number Title Priority Date Filing Date
HU402888A HU201324B (en) 1988-07-29 1988-07-29 New process for production of substituated 1,2,4-triasole (4,3-a)-piridin-2 (2h)-on

Country Status (1)

Country Link
HU (1) HU201324B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017505302A (en) * 2014-01-21 2017-02-16 ピラマル エンタープライジーズ リミテッド Improved process for producing trazodone and its hydrochloride
PT3749668T (en) * 2018-02-07 2022-06-02 Aziende Chimiche Riunite Angelini Francesco A C R Continuous process for the preparation of trazodone

Also Published As

Publication number Publication date
HU201324B (en) 1990-10-28

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee