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HUT42767A - Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one - Google Patents

Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Info

Publication number
HUT42767A
HUT42767A HU854264A HU426485A HUT42767A HU T42767 A HUT42767 A HU T42767A HU 854264 A HU854264 A HU 854264A HU 426485 A HU426485 A HU 426485A HU T42767 A HUT42767 A HU T42767A
Authority
HU
Hungary
Prior art keywords
benzothiazepin
acetoxy
dihydro
methoxy
dimethyl
Prior art date
Application number
HU854264A
Other languages
Hungarian (hu)
Other versions
HU195795B (en
Inventor
Tibor Gizur
Kalman Harsanyi
Janosne Aracs
Jozsef Felmeri
Katalin Berki
Laszlone Demeter
Zsuzsanna Vincze
Ferenc Trischler
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU854264A priority Critical patent/HU195795B/en
Priority to BE0/217372A priority patent/BE905704A/en
Priority to CA000522187A priority patent/CA1309714C/en
Priority to AT0294786A priority patent/AT393837B/en
Priority to JP61263630A priority patent/JPS62108872A/en
Priority to ES8602911A priority patent/ES2001146A6/en
Publication of HUT42767A publication Critical patent/HUT42767A/en
Publication of HU195795B publication Critical patent/HU195795B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU854264A 1985-11-06 1985-11-06 Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one HU195795B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
HU854264A HU195795B (en) 1985-11-06 1985-11-06 Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one
BE0/217372A BE905704A (en) 1985-11-06 1986-11-05 PROCESS FOR THE PREPARATION OF (2S, 3S) - 3 - ACETOXY - 5 - (N, N '- DIMETHYLAMINOETHYL) - 2 - (4 - METHOXYPHENYL) - 2,3 - DIHYDRO -1,5 - BENZOTHIAZEPIN - 4 (5H) - ONE.
CA000522187A CA1309714C (en) 1985-11-06 1986-11-05 Process for the preparation of (2s,3s)-3-acetoxy-5-(n, n-dimethylaminoethyl)-2-(4-methoxyphenyl)-2,3-dihydro- 1,5-benzothiazepin-4(5h)-one
AT0294786A AT393837B (en) 1985-11-06 1986-11-05 METHOD FOR PRODUCING THE HYDROCHLORIDE OF (2S, 3S) -3-ACETOXY-5- (2- (N, N-DIMETHYLAMINOETHYL) -2- (4-METHOXYPHENYL) -2,3-DIHYDRO-1,5-BENZOTHIAZ PIN- 4 (5H) -ON
JP61263630A JPS62108872A (en) 1985-11-06 1986-11-05 Production of dilutiazem
ES8602911A ES2001146A6 (en) 1985-11-06 1986-11-05 Production of dilutiazem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU854264A HU195795B (en) 1985-11-06 1985-11-06 Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Publications (2)

Publication Number Publication Date
HUT42767A true HUT42767A (en) 1987-08-28
HU195795B HU195795B (en) 1988-07-28

Family

ID=10967486

Family Applications (1)

Application Number Title Priority Date Filing Date
HU854264A HU195795B (en) 1985-11-06 1985-11-06 Process for preparing (2s,3s)-3-acetoxy-5-(n,n-dimethyl-amino-ethyl)-2-(h-methoxy-phenyl)-2,3-dihydro-1,5-benzothiazepin-h(5h)-one

Country Status (6)

Country Link
JP (1) JPS62108872A (en)
AT (1) AT393837B (en)
BE (1) BE905704A (en)
CA (1) CA1309714C (en)
ES (1) ES2001146A6 (en)
HU (1) HU195795B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6450872A (en) * 1987-08-21 1989-02-27 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
IT1226301B (en) * 1988-07-26 1990-12-27 Zambon Spa PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR THE SYNTHESIS OF DILTIAZEM.

Also Published As

Publication number Publication date
HU195795B (en) 1988-07-28
ES2001146A6 (en) 1988-04-16
CA1309714C (en) 1992-11-03
JPH0354939B2 (en) 1991-08-21
ATA294786A (en) 1991-06-15
JPS62108872A (en) 1987-05-20
AT393837B (en) 1991-12-27
BE905704A (en) 1987-03-02

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HPC4 Succession in title of patentee

Owner name: ZAMBON GROUP S.P.A., IT

HMM4 Cancellation of final prot. due to non-payment of fee