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HUP9904180A2 - Tiosavszármazékokkal szubsztituált,monociklusos,nitrogéntartalmú heteroaromás vegyületek és ezeket tartalmazó gyógyszerkészítmények - Google Patents

Tiosavszármazékokkal szubsztituált,monociklusos,nitrogéntartalmú heteroaromás vegyületek és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP9904180A2
HUP9904180A2 HU9904180A HUP9904180A HUP9904180A2 HU P9904180 A2 HUP9904180 A2 HU P9904180A2 HU 9904180 A HU9904180 A HU 9904180A HU P9904180 A HUP9904180 A HU P9904180A HU P9904180 A2 HUP9904180 A2 HU P9904180A2
Authority
HU
Hungary
Prior art keywords
heteroaromatics
pharmaceutical compositions
compositions containing
acid derived
monocyclic
Prior art date
Application number
HU9904180A
Other languages
English (en)
Inventor
Monica J. Kochanny
Michael M. Morrissey
Howard P. Ng
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of HUP9904180A2 publication Critical patent/HUP9904180A2/hu
Publication of HUP9904180A3 publication Critical patent/HUP9904180A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A találmány tárgyát az (I)-(VII) általánős képletű, tiősavszárma-zékőkkal szűbsztitűált, mőnőciklűsős, nitrőgénatőmőt tartalmazóheterőciklűsős benzamidinszármazékők és gyógyszerészetileg elfőgadhatósóik képezik, amelyek a véralvadáskaszkádban a Xa faktőrt gátőlják, ésezáltal véralvadásgátlóként használhatók. A találmány tárgyáhőztartőznak még a fenti származékőkat vagy gyógyszerészetilegelfőgadható sóikat tartalmazó gyógyszerkészítmények is. ŕ
HU9904180A 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them HUP9904180A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (2)

Publication Number Publication Date
HUP9904180A2 true HUP9904180A2 (hu) 2000-09-28
HUP9904180A3 HUP9904180A3 (en) 2000-11-28

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904180A HUP9904180A3 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (6) US6004985A (hu)
EP (1) EP0934310B1 (hu)
JP (1) JP3768244B2 (hu)
KR (1) KR20000048966A (hu)
CN (1) CN1111159C (hu)
AT (1) ATE288908T1 (hu)
AU (1) AU730060B2 (hu)
CA (1) CA2268172A1 (hu)
CZ (1) CZ122799A3 (hu)
DE (1) DE69732490T2 (hu)
DK (1) DK0934310T3 (hu)
ES (1) ES2236828T3 (hu)
HK (1) HK1020958A1 (hu)
HU (1) HUP9904180A3 (hu)
IL (1) IL129056A0 (hu)
NO (1) NO991594L (hu)
NZ (1) NZ334758A (hu)
PL (1) PL332602A1 (hu)
PT (1) PT934310E (hu)
SK (1) SK46499A3 (hu)
WO (1) WO1998015547A1 (hu)

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CA2533377C (en) 2003-07-30 2012-11-27 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
CA2584295C (en) 2004-11-24 2014-08-26 Rigel Pharmaceuticals, Inc. Spiro-2, 4-pyrimidinediamine compounds and their uses
JP4801096B2 (ja) 2005-01-19 2011-10-26 ライジェル ファーマシューティカルズ， インコーポレイテッド ２，４−ピリミジンジアミン化合物のプロドラッグおよびそれらの使用
CA2604551A1 (en) * 2005-05-03 2007-03-08 Rigel Pharmaceuticals, Inc. Jak kinase inhibitors and their uses
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
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BRPI0910921B1 (pt) 2008-04-16 2022-06-21 Portola Pharmaceuticals, Inc Inibidores de proteína syk quinase, composição farmacêutica, kit e usos dos referidos inibidores
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Also Published As

Publication number Publication date
IL129056A0 (en) 2000-02-17
CN1111159C (zh) 2003-06-11
HUP9904180A3 (en) 2000-11-28
NZ334758A (en) 2000-11-24
WO1998015547A1 (en) 1998-04-16
AU4624097A (en) 1998-05-05
EP0934310B1 (en) 2005-02-09
DE69732490D1 (en) 2005-03-17
NO991594L (no) 1999-06-08
US6150382A (en) 2000-11-21
AU730060B2 (en) 2001-02-22
US6166014A (en) 2000-12-26
KR20000048966A (ko) 2000-07-25
DE69732490T2 (de) 2006-04-27
PT934310E (pt) 2005-06-30
US6034084A (en) 2000-03-07
PL332602A1 (en) 1999-09-27
NO991594D0 (no) 1999-03-31
CA2268172A1 (en) 1998-04-16
US6004985A (en) 1999-12-21
CZ122799A3 (cs) 1999-09-15
CN1233247A (zh) 1999-10-27
SK46499A3 (en) 2000-04-10
ATE288908T1 (de) 2005-02-15
DK0934310T3 (da) 2005-05-30
US6162807A (en) 2000-12-19
ES2236828T3 (es) 2005-07-16
JP2001501632A (ja) 2001-02-06
HK1020958A1 (en) 2004-03-19
US6221886B1 (en) 2001-04-24
EP0934310A1 (en) 1999-08-11
JP3768244B2 (ja) 2006-04-19

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