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HUP9902683A2 - 3,4-Difenil-krománok alkalmazása menopauzális szimptómák kezelésére vagy megelőző kezelésére alkalmas gyógyszerkészítmények előállítására - Google Patents

3,4-Difenil-krománok alkalmazása menopauzális szimptómák kezelésére vagy megelőző kezelésére alkalmas gyógyszerkészítmények előállítására

Info

Publication number
HUP9902683A2
HUP9902683A2 HU9902683A HUP9902683A HUP9902683A2 HU P9902683 A2 HUP9902683 A2 HU P9902683A2 HU 9902683 A HU9902683 A HU 9902683A HU P9902683 A HUP9902683 A HU P9902683A HU P9902683 A2 HUP9902683 A2 HU P9902683A2
Authority
HU
Hungary
Prior art keywords
prophylaxis
manufacture
treatment
pharmaceutical composition
menopausal symptoms
Prior art date
Application number
HU9902683A
Other languages
English (en)
Inventor
Steven Bain
Birgitte Hjort Guldhammer
Niels Korsgaard
Virender Mohan Labroo
James Robertson Piggott
Michael Shalmi
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP9902683A2 publication Critical patent/HUP9902683A2/hu
Publication of HUP9902683A3 publication Critical patent/HUP9902683A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

A találmány tárgya eljárás (I) általános képletű vegyületet vagygyógyszerészetileg elfogadható sóját, ahol R1, R4 és R5 jelentése egymástól függetlenül hidrogénatom,hidroxilcsoport, halogénatom, trifluor-metil-csoport, 1-6 szénatomosalkilcsoport, 1-6 szénatomos alkoxicsoport vagy tercier amino-1-6szénatomos alkoxi-csoport, és R2 és R3 jelentése egymástól függetlenül hidrogénatom vagy 1-6szénatomos alkilcsoport, tartalmazó gyógyszerkészítmények előállítása. Ó
HU9902683A 1996-01-11 1997-01-09 Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms HUP9902683A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US983496P 1996-01-11 1996-01-11
US67826196A 1996-07-11 1996-07-11
PCT/DK1997/000008 WO1997025035A1 (en) 1996-01-11 1997-01-09 Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms

Publications (2)

Publication Number Publication Date
HUP9902683A2 true HUP9902683A2 (hu) 2001-04-28
HUP9902683A3 HUP9902683A3 (en) 2001-08-28

Family

ID=26679921

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9902683A HUP9902683A3 (en) 1996-01-11 1997-01-09 Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of menopausal symptoms

Country Status (12)

Country Link
EP (1) EP0873120A1 (hu)
JP (1) JP2000506505A (hu)
KR (1) KR19990077156A (hu)
AU (1) AU1367297A (hu)
BR (1) BR9706967A (hu)
CA (1) CA2241623A1 (hu)
CZ (1) CZ217298A3 (hu)
HU (1) HUP9902683A3 (hu)
IL (1) IL124882A0 (hu)
NO (1) NO983178L (hu)
PL (1) PL327831A1 (hu)
WO (1) WO1997025035A1 (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
DE60018215T2 (de) * 1999-12-30 2006-02-09 Signal Pharmaceuticals Llc, San Diego Verbindungen und verfahren zur modulation von estrogen rezeptoren
EP1794141B1 (en) 2004-09-21 2011-11-09 Marshall Edwards, Inc. Substituted chroman derivatives, medicaments and use in therapy
US8080675B2 (en) 2004-09-21 2011-12-20 Marshall Edwards, Inc. Chroman derivatives, medicaments and use in therapy
AP2365A (en) 2004-10-20 2012-02-20 Endorech Inc Sex steroid precursors alone or in combination with a selective estrogen receptor modulator and/or with estrogens and/or a type 5 CGMP phosphodiesterase inhibitor for the prevention and treatment of vaginal dryness and sexual dysfunction in postmenopausal women.
US8268806B2 (en) 2007-08-10 2012-09-18 Endorecherche, Inc. Pharmaceutical compositions
SG185311A1 (en) 2007-10-16 2012-11-29 Repros Therapeutics Inc Trans-clomiphene for metabolic syndrome
US20100317635A1 (en) 2009-06-16 2010-12-16 Endorecherche, Inc. Treatment of hot flushes, vasomotor symptoms, and night sweats with sex steroid precursors in combination with selective estrogen receptor modulators
WO2011156908A1 (en) 2010-06-16 2011-12-22 Endorecherche, Inc. Methods of treating or preventing estrogen-related diseases
EP2635273B1 (en) 2010-11-01 2020-01-08 MEI Pharma, Inc. Isoflavonoid compositions and methods for the treatment of cancer
WO2013130832A1 (en) 2012-02-29 2013-09-06 Repros Therapeutics Inc. Combination therapy for treating androgen deficiency
SI2953938T1 (en) 2014-02-07 2018-01-31 Novogen Ltd. Functionalized benzopyran compounds and their use
US9744177B2 (en) 2014-03-10 2017-08-29 Endorecherche, Inc. Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM
AU2016215515B2 (en) 2015-02-02 2020-04-30 Mei Pharma, Inc. Combination therapies
WO2017081171A1 (en) 2015-11-10 2017-05-18 Paracrine Therapeutics Ab Treatment of er-negative breast cancer with an pdgf-cc inhibitor and an anti estrogen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency

Also Published As

Publication number Publication date
CZ217298A3 (cs) 1999-01-13
BR9706967A (pt) 1999-05-04
WO1997025035A1 (en) 1997-07-17
KR19990077156A (ko) 1999-10-25
PL327831A1 (en) 1999-01-04
HUP9902683A3 (en) 2001-08-28
NO983178L (no) 1998-07-10
CA2241623A1 (en) 1997-07-17
IL124882A0 (en) 1999-01-26
JP2000506505A (ja) 2000-05-30
AU1367297A (en) 1997-08-01
EP0873120A1 (en) 1998-10-28

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