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HUP1300496A2 - Stabil kombinációs gyógyszerkészítmény - Google Patents

Stabil kombinációs gyógyszerkészítmény

Info

Publication number
HUP1300496A2
HUP1300496A2 HU1300496A HUP1300496A HUP1300496A2 HU P1300496 A2 HUP1300496 A2 HU P1300496A2 HU 1300496 A HU1300496 A HU 1300496A HU P1300496 A HUP1300496 A HU P1300496A HU P1300496 A2 HUP1300496 A2 HU P1300496A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical composition
stable pharmaceutical
stable
composition
pharmaceutical
Prior art date
Application number
HU1300496A
Other languages
English (en)
Inventor
Molnar Eva Gutine
Zsigmond Zsolt Dr
Zoltanne Toth
Orban Adam Dr
Original Assignee
Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag filed Critical Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag
Priority to HU1300496A priority Critical patent/HUP1300496A2/hu
Priority to PCT/HU2014/000072 priority patent/WO2015022560A1/en
Priority to PCT/HU2014/000071 priority patent/WO2015022559A1/en
Priority to EA201690395A priority patent/EA033291B1/ru
Priority to HU1600414A priority patent/HU231052B1/hu
Publication of HUP1300496A2 publication Critical patent/HUP1300496A2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU1300496A 2013-08-16 2013-08-16 Stabil kombinációs gyógyszerkészítmény HUP1300496A2 (hu)

Priority Applications (5)

Application Number Priority Date Filing Date Title
HU1300496A HUP1300496A2 (hu) 2013-08-16 2013-08-16 Stabil kombinációs gyógyszerkészítmény
PCT/HU2014/000072 WO2015022560A1 (en) 2013-08-16 2014-08-15 Stable pharmaceutical composition containing bisoprolol and ramipril
PCT/HU2014/000071 WO2015022559A1 (en) 2013-08-16 2014-08-15 Pharmaceutical composition containing rosuvastatin and ramipril
EA201690395A EA033291B1 (ru) 2013-08-16 2014-08-15 Единица дозирования, содержащая рамиприл и бисопролола гемифумарат, способ ее получения и способ лечения гипертензии
HU1600414A HU231052B1 (hu) 2013-08-16 2014-08-15 Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU1300496A HUP1300496A2 (hu) 2013-08-16 2013-08-16 Stabil kombinációs gyógyszerkészítmény

Publications (1)

Publication Number Publication Date
HUP1300496A2 true HUP1300496A2 (hu) 2015-03-02

Family

ID=89991232

Family Applications (2)

Application Number Title Priority Date Filing Date
HU1300496A HUP1300496A2 (hu) 2013-08-16 2013-08-16 Stabil kombinációs gyógyszerkészítmény
HU1600414A HU231052B1 (hu) 2013-08-16 2014-08-15 Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU1600414A HU231052B1 (hu) 2013-08-16 2014-08-15 Bisoprololt és ramiprilt tartalmazó stabil kombinációs gyógyszerkészítmény

Country Status (3)

Country Link
EA (1) EA033291B1 (hu)
HU (2) HUP1300496A2 (hu)
WO (2) WO2015022560A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3501502A1 (en) * 2017-12-20 2019-06-26 Midas Pharma GmbH Fixed dosed pharmaceutical compositions comprising amlodipine, ramipril and atorvastatin
RS66060B1 (sr) 2020-02-10 2024-11-29 Adamed Pharma S A Sastav koji sadrži ramipril i indapamid
CN115068434B (zh) * 2022-08-03 2023-05-09 昆山龙灯瑞迪制药有限公司 一种雷米普利片的制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU88621I2 (fr) 1980-10-23 1995-09-01 Schering Corp Sandopril
DE3226768A1 (de) 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3739690A1 (de) 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
US20030215526A1 (en) 2002-03-08 2003-11-20 Scott Stofik Stable formulations of angiotensin converting enzyme (ACE) inhibitors
CA2483099A1 (en) * 2002-05-03 2003-11-13 Hexal Ag Stable pharmaceutical formulation for a combination of a statin and an ace inhibitor
PL1635792T3 (pl) 2003-06-26 2009-08-31 Teva Pharmaceutical Industries Ltd Stabilne kompozycje farmaceutyczne pochodnych kwasu 2-aza-bicyklo[3.3.0]-oktano-3-karboksylowego
EP1694308A1 (en) 2003-10-30 2006-08-30 Lupin Ltd. Stable formulations of ace inhibitors and methods for preparation thereof
GB2394660A (en) 2003-12-17 2004-05-05 Niche Generics Ltd Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide
EA011862B1 (ru) 2004-03-24 2009-06-30 Актавис Груп Хф. Композиции рамиприла
EP1817007A2 (en) * 2004-11-05 2007-08-15 King Pharmaceuticals Research and Development Inc. Stabilized individually coated ramipril particles, compositions and methods
WO2007056442A1 (en) * 2005-11-07 2007-05-18 King Pharmaceuticals Research & Development, Inc. Compositions of stabilized ramipril in combination with another active agent
CN100374462C (zh) 2005-11-21 2008-03-12 大连帝恩生物工程有限公司 截短胰高血糖素样肽1(sGLP-1)、制法及其应用
US20070232680A1 (en) 2006-04-04 2007-10-04 Vijayabhaskar Bolugoddu Preparation of ramipril and stable pharmaceutical compositions
BRPI0710172A2 (pt) 2006-04-19 2011-08-23 Teva Pharma composição farmacêutica estável de ácido carboxìlico derivado de 2-aza-biciclo[3,3,0]-octana-3
AU2007264414A1 (en) 2006-06-30 2008-01-03 Alphapharm Pty Ltd A stabilised composition comprising ACE inhibitors
US20110086092A1 (en) 2006-08-08 2011-04-14 Accu-Break Technologies, Inc. Pharmacuetical tablets containing a plurality of active ingredients
WO2008065485A2 (en) 2006-10-19 2008-06-05 Torrent Pharmaceuticals Limited Stable pharmaceutical compositions of a calcium channel blocker and an ace inhibitor
CA2677623C (en) 2007-02-09 2015-04-07 Alphapharm Pty Ltd A dosage form containing two or more active pharmaceutical ingredients in different physical forms
WO2008132756A1 (en) 2007-05-01 2008-11-06 Lupin Limited Stable pharmaceutical compositions of ramipril
HU230877B1 (hu) 2008-09-30 2018-11-29 EGIS Gyógyszergyár NyR Stabil kombinációs gyógyszerkészítmény
EP2272874A1 (en) 2009-07-10 2011-01-12 CSL Behring GmbH Role of PLD1 in thrombus formation and integrin alpha IIb beta 3 activation
CN101612403A (zh) 2009-08-13 2009-12-30 王丽燕 含钙拮抗剂、ace抑制剂和他汀类药的药物组合物
WO2013121233A1 (en) 2012-02-17 2013-08-22 Egis Gyógyszergyár Nyilvánosan Működö Részvénytársaság Pharmaceutical formulation having improved stability

Also Published As

Publication number Publication date
EA033291B1 (ru) 2019-09-30
EA201690395A1 (ru) 2016-07-29
WO2015022560A8 (en) 2015-05-14
HUP1600414A2 (hu) 2016-09-28
HU231052B1 (hu) 2020-02-28
WO2015022560A1 (en) 2015-02-19
WO2015022559A1 (en) 2015-02-19

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Legal Events

Date Code Title Description
FC4A Lapse of provisional application due to refusal