HUP0303144A3 - Process for the production of substituted 2-(2-pyridylmethyl)sulfinyl-1h-benzimidazoles - Google Patents

Process for the production of substituted 2-(2-pyridylmethyl)sulfinyl-1h-benzimidazoles

Info

Publication number: HUP0303144A3
Authority: HU; Hungary
Prior art keywords: benzimidazoles; pyridylmethyl; sulfinyl; substituted; production
Prior art date: 2001-02-02

Application number

HU0303144A

Other languages

English (en)

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-02

Filing date

2002-02-04

Publication date

2007-08-28

2002-02-04 Application filed by Teva Pharma filed Critical Teva Pharma

2004-03-01 Publication of HUP0303144A2 publication Critical patent/HUP0303144A2/hu

2007-08-28 Publication of HUP0303144A3 publication Critical patent/HUP0303144A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HU0303144A 2001-02-02 2002-02-04 Process for the production of substituted 2-(2-pyridylmethyl)sulfinyl-1h-benzimidazoles HUP0303144A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26616201P	2001-02-02	2001-02-02
PCT/US2002/003225 WO2002062786A1 (en)	2001-02-02	2002-02-04	Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles

Publications (2)

Publication Number	Publication Date
HUP0303144A2 HUP0303144A2 (hu)	2004-03-01
HUP0303144A3 true HUP0303144A3 (en)	2007-08-28

Family

ID=23013433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0303144A HUP0303144A3 (en)	2001-02-02	2002-02-04	Process for the production of substituted 2-(2-pyridylmethyl)sulfinyl-1h-benzimidazoles

Country Status (19)

Country	Link
US (3)	US7129358B2 (hu)
EP (2)	EP1363901A4 (hu)
JP (1)	JP2004524303A (hu)
KR (1)	KR20040029966A (hu)
CN (3)	CN1876647A (hu)
CA (1)	CA2436467A1 (hu)
CZ (1)	CZ20032351A3 (hu)
DE (1)	DE02706135T1 (hu)
ES (1)	ES2209678T1 (hu)
HR (1)	HRP20030691A2 (hu)
HU (1)	HUP0303144A3 (hu)
IS (1)	IS6897A (hu)
MX (1)	MXPA03006904A (hu)
NO (1)	NO20033433L (hu)
PL (1)	PL368563A1 (hu)
SK (1)	SK10792003A3 (hu)
WO (1)	WO2002062786A1 (hu)
YU (1)	YU61103A (hu)
ZA (1)	ZA200305652B (hu)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU61103A (sh)	2001-02-02	2006-05-25	Teva Pharmaceutical Industries Ltd.	Postupci za produkciju supstituisanih 2-(2-piridilmetil) sulfinil-1h-benzimidazola
PL373539A1 (en) *	2002-03-27	2005-09-05	Teva Pharmaceutical Industries Ltd.	Lansoprazole polymorphs and processes for preparation thereof
EP1467987A1 (en) *	2002-07-26	2004-10-20	Teva Pharmaceutical Industries Ltd.	Preparation of lansoprazole and related compounds
US6909004B2 (en) *	2002-08-21	2005-06-21	Teva Pharmaceutical Industries Ltd.	Method for the purification of lansoprazole
WO2004046135A1 (en) *	2002-11-18	2004-06-03	Teva Pharmaceutical Industries Ltd.	Stable lansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
CA2510849A1 (en) *	2002-12-19	2004-07-08	Teva Pharmaceutical Industries Ltd	Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
CA2515130A1 (en) *	2003-02-05	2004-08-26	Teva Pharmaceutical Industries Ltd.	Method of stabilizing lansoprazole
WO2004080961A2 (en) *	2003-03-12	2004-09-23	Teva Pharmaceutical Industries Ltd.	Crystalline and amorphous solids of pantoprazole and processes for their preparation
CA2528993A1 (en) *	2003-06-10	2004-12-23	Teva Pharmaceutical Industries Ltd.	Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
FR2871800B1 (fr) *	2004-06-17	2006-08-25	Sidem Pharma Sa Sa	Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
WO2006064249A2 (en) *	2004-12-16	2006-06-22	Cipla Limited	Process for the preparation of pantoprazole sodium
EP1681056A1 (en)	2005-01-14	2006-07-19	Krka Tovarna Zdravil, D.D., Novo Mesto	Process for preparing lansoprazole
AR054113A1 (es) *	2005-05-06	2007-06-06	Medichem Sa	Forma cristalina solida de pantoprazol como acido libre, sales derivadas del mismo y proceso para su preparacion
CN1919844B (zh) *	2006-09-01	2010-05-12	武汉工程大学	水相氧化合成兰索拉唑的方法
WO2010039885A2 (en) *	2008-09-30	2010-04-08	Teva Pharmaceutical Industries Ltd.	Crystalline forms of dexlansoprazole
WO2010134099A1 (en) *	2009-05-21	2010-11-25	Cadila Healthcare Limited	One pot process for preparing omeprazole and related compounds
CN108623564B (zh) *	2017-03-17	2022-11-04	江苏豪森药业集团有限公司	一种雷贝拉唑类似物的制备方法
CN111072633A (zh) *	2019-12-19	2020-04-28	山东达因海洋生物制药股份有限公司	一种埃索美拉唑镁三水合物的制备方法
CN112174934B (zh) *	2020-10-15	2023-12-22	成都百泉生物医药科技有限公司	一种奥美拉唑的合成方法及其合成设备

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1140119A (en)	1978-04-03	1983-01-25	Joseph Torremans	N-heterocyclyl-4-piperidinamines
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
GB2069492B (en)	1980-02-20	1984-02-29	Wyeth John & Brother Ltd	Sulphur compounds
SE8300736D0 (sv) *	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
DK171989B1 (da)	1987-08-04	1997-09-08	Takeda Chemical Industries Ltd	Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
SE9002043D0 (sv)	1990-06-07	1990-06-07	Astra Ab	Improved method for synthesis
WO1993006097A1 (en)	1991-09-20	1993-04-01	Merck & Co., Inc.	Novel process for the preparation of anti-ulcer agents
ES2063705B1 (es) *	1993-06-14	1995-07-16	S A L V A T Lab Sa	Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion.
SK283805B6 (sk) *	1996-09-09	2004-02-03	Slovakofarma, A. S.	Spôsob prípravy omeprazolu
SE9704183D0 (sv)	1997-11-14	1997-11-14	Astra Ab	New process
ATE303809T1 (de) *	1997-12-08	2005-09-15	Altana Pharma Ag	Orale verabreichungsform enthaltend einen protonenpumpeninhbitor (z.b. pantoprazole)
GB9805558D0 (en) *	1998-03-17	1998-05-13	Knoll Ag	Chemical process`
US6303787B1 (en)	1998-05-27	2001-10-16	Natco Pharma Limited	Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates
SI20019A (sl) *	1998-07-13	2000-02-29	LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d.	Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
JP4047993B2 (ja) *	1999-01-04	2008-02-13	理想科学工業株式会社	孔版印刷方法
US6245913B1 (en) *	1999-06-30	2001-06-12	Wockhardt Europe Limited	Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2163372B1 (es)	2000-03-13	2003-05-01	Esteve Quimica Sa	Procedimiento de oxidacion de un grupo tioeter a sulfoxido.
YU61103A (sh)	2001-02-02	2006-05-25	Teva Pharmaceutical Industries Ltd.	Postupci za produkciju supstituisanih 2-(2-piridilmetil) sulfinil-1h-benzimidazola

2002
- 2002-02-04 YU YU61103A patent/YU61103A/sh unknown
- 2002-02-04 US US10/066,850 patent/US7129358B2/en not_active Expired - Fee Related
- 2002-02-04 SK SK1079-2003A patent/SK10792003A3/sk not_active Application Discontinuation
- 2002-02-04 EP EP02706135A patent/EP1363901A4/en not_active Withdrawn
- 2002-02-04 ES ES02706135T patent/ES2209678T1/es active Pending
- 2002-02-04 CZ CZ20032351A patent/CZ20032351A3/cs unknown
- 2002-02-04 JP JP2002563139A patent/JP2004524303A/ja active Pending
- 2002-02-04 KR KR10-2003-7010217A patent/KR20040029966A/ko not_active Application Discontinuation
- 2002-02-04 HU HU0303144A patent/HUP0303144A3/hu unknown
- 2002-02-04 CN CNA2006100819206A patent/CN1876647A/zh active Pending
- 2002-02-04 CN CNA200510086094XA patent/CN1781918A/zh active Pending
- 2002-02-04 WO PCT/US2002/003225 patent/WO2002062786A1/en active Application Filing
- 2002-02-04 EP EP08010970A patent/EP1970374A1/en not_active Ceased
- 2002-02-04 CN CNB028044851A patent/CN100347167C/zh not_active Expired - Fee Related
- 2002-02-04 MX MXPA03006904A patent/MXPA03006904A/es not_active Application Discontinuation
- 2002-02-04 CA CA002436467A patent/CA2436467A1/en not_active Abandoned
- 2002-02-04 ZA ZA200305652A patent/ZA200305652B/en unknown
- 2002-02-04 PL PL02368563A patent/PL368563A1/xx not_active Application Discontinuation
- 2002-02-04 DE DE0001363901T patent/DE02706135T1/de active Pending
2003
- 2003-07-29 IS IS6897A patent/IS6897A/is unknown
- 2003-08-01 NO NO20033433A patent/NO20033433L/no not_active Application Discontinuation
- 2003-09-01 HR HR20030691A patent/HRP20030691A2/xx not_active Application Discontinuation
2006
- 2006-09-05 US US11/514,964 patent/US20060293363A1/en not_active Abandoned
2007
- 2007-10-09 US US11/973,744 patent/US20080091024A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ZA200305652B (en)	2004-07-22
CN1781918A (zh)	2006-06-07
NO20033433L (no)	2003-09-25
CA2436467A1 (en)	2002-08-15
CN100347167C (zh)	2007-11-07
MXPA03006904A (es)	2004-12-06
CN1876647A (zh)	2006-12-13
CN1489585A (zh)	2004-04-14
US20060293363A1 (en)	2006-12-28
SK10792003A3 (sk)	2004-07-07
US7129358B2 (en)	2006-10-31
EP1970374A1 (en)	2008-09-17
WO2002062786A1 (en)	2002-08-15
ES2209678T1 (es)	2004-07-01
PL368563A1 (en)	2005-04-04
KR20040029966A (ko)	2004-04-08
IS6897A (is)	2003-07-29
NO20033433D0 (no)	2003-08-01
US20030036554A1 (en)	2003-02-20
HUP0303144A2 (hu)	2004-03-01
DE02706135T1 (de)	2004-05-19
CZ20032351A3 (cs)	2004-08-18
YU61103A (sh)	2006-05-25
EP1363901A4 (en)	2005-08-31
US20080091024A1 (en)	2008-04-17
JP2004524303A (ja)	2004-08-12
EP1363901A1 (en)	2003-11-26
HRP20030691A2 (en)	2005-04-30

Publication	Publication Date	Title
HUP0303144A3 (en)	2007-08-28	Process for the production of substituted 2-(2-pyridylmethyl)sulfinyl-1h-benzimidazoles
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GB0125653D0 (en)	2001-12-19	Process for the production of detergent granules
GC0000365A (en)	2007-03-31	Process for the production of olefins
HK1051190A1 (en)	2003-07-25	Process for the preparation of 2-(4-alkyl-1-piperazinyl-benzaldehyde and -benzylidenyl compounds.
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AU2002314365A1 (en)	2003-01-21	Process for the production of allicin
SI1399437T1 (en)	2005-06-30	Method for the production of triazolylmethylepoxides

Legal Events

Date	Code	Title	Description
2010-10-28	FD9A	Lapse of provisional protection due to non-payment of fees