HUP0300290A2 - Érkárosító hatású kombinácíós készítmény és terápia - Google Patents
Érkárosító hatású kombinácíós készítmény és terápiaInfo
- Publication number
- HUP0300290A2 HUP0300290A2 HU0300290A HUP0300290A HUP0300290A2 HU P0300290 A2 HUP0300290 A2 HU P0300290A2 HU 0300290 A HU0300290 A HU 0300290A HU P0300290 A HUP0300290 A HU P0300290A HU P0300290 A2 HUP0300290 A2 HU P0300290A2
- Authority
- HU
- Hungary
- Prior art keywords
- subject
- combination therapies
- platinum
- warm
- production
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- 230000000254 damaging effect Effects 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 230000003966 vascular damage Effects 0.000 abstract 2
- 229940123237 Taxane Drugs 0.000 abstract 1
- 239000012876 carrier material Substances 0.000 abstract 1
- 239000013066 combination product Substances 0.000 abstract 1
- 229940127555 combination product Drugs 0.000 abstract 1
- 230000005865 ionizing radiation Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Glass Compositions (AREA)
Abstract
A találmány tárgyát képezi az (1) képletű ZD6126 vagy gyógyászatilagalkalmazható sója és egy platina típusú tumorellenes szer vagy egytaxán felhasználása melegvérűeken, köztük embereken érkárosító hatástelőidéző gyógyszerek gyártásához. A találmány tárgyát képezi továbbá aZD6126 vagy gyógyászatilag alkalmazható sójának felhasználása ionizálóbesugárzással kezelt melegvérűeken, köztük embereken érkárosító hatástelőidéző gyógyszerek gyártásához. A találmány tárgya továbbákombinációs termék, gyógyszerkészlet vagy gyógyászati készítmény, amiZD6126-ot vagy gyógyászatilag alkalmazható sóját és egy platina típusútumorellenes szert vagy egy taxánt tartalmaz, adott esetbengyógyászati célokra alkalmas excipienssel és/vagy hordozóanyaggalegyesítve. Ó
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0007740A GB0007740D0 (en) | 2000-03-31 | 2000-03-31 | Combination therapy |
GB0013927A GB0013927D0 (en) | 2000-06-08 | 2000-06-08 | Combination therapy |
GB0014908A GB0014908D0 (en) | 2000-06-20 | 2000-06-20 | Combination therapy |
PCT/GB2001/001317 WO2001074368A1 (en) | 2000-03-31 | 2001-03-27 | Combination therapies with vascular damaging activity |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0300290A2 true HUP0300290A2 (hu) | 2003-06-28 |
HUP0300290A3 HUP0300290A3 (en) | 2005-12-28 |
Family
ID=27255634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0300290A HUP0300290A3 (en) | 2000-03-31 | 2001-03-27 | Combination therapies with vascular damaging activity |
Country Status (23)
Country | Link |
---|---|
US (2) | US6906048B2 (hu) |
EP (1) | EP1272199B1 (hu) |
JP (1) | JP2003528920A (hu) |
KR (1) | KR20020087456A (hu) |
CN (1) | CN1430515A (hu) |
AT (1) | ATE287267T1 (hu) |
AU (2) | AU2001242581B2 (hu) |
BR (1) | BR0109672A (hu) |
CA (1) | CA2402539A1 (hu) |
CZ (1) | CZ20023228A3 (hu) |
DE (1) | DE60108489T2 (hu) |
EE (1) | EE200200565A (hu) |
ES (1) | ES2236199T3 (hu) |
HU (1) | HUP0300290A3 (hu) |
IL (1) | IL151628A0 (hu) |
IS (1) | IS6558A (hu) |
MX (1) | MXPA02009604A (hu) |
NO (1) | NO20024646L (hu) |
NZ (1) | NZ521025A (hu) |
PL (1) | PL366379A1 (hu) |
PT (1) | PT1272199E (hu) |
SK (1) | SK13912002A3 (hu) |
WO (1) | WO2001074368A1 (hu) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070021392A1 (en) * | 2000-03-31 | 2007-01-25 | Davis Peter D | Divided dose therapies with vascular damaging activity |
GB0011903D0 (en) * | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
FR2834641B1 (fr) * | 2002-01-14 | 2005-04-22 | Ct Regional De Lutte Contre Le | Protection de la neurotoxicite de l'oxaliplatine par administration de calcium et de magnesium |
KR20040103964A (ko) * | 2002-04-16 | 2004-12-09 | 아스트라제네카 아베 | 암 치료를 위한 조합 요법 |
GB0223379D0 (en) * | 2002-10-09 | 2002-11-13 | Angiogene Pharm Ltd | Combination therapy |
FR2848212B1 (fr) * | 2002-12-06 | 2006-10-27 | Aventis Pharma Sa | Derives de la colchicine, procede de preparation, produits obtenus par ce procede et utilisation |
CA2529409A1 (en) * | 2003-06-18 | 2004-12-29 | Angiogene Pharmaceuticals Limited | Compositions comprising zd6126 together with 5-fu, cpt-11 or 5-fu and cpt-11 having vascular damaging activity for treating e.g. colorectal cancer |
GB0316123D0 (en) * | 2003-07-10 | 2003-08-13 | Astrazeneca Ab | Combination therapy |
US9149489B2 (en) * | 2006-04-27 | 2015-10-06 | Board Of Regents, University Of Texas System | Inhibitors of glycolysis useful in the treatment of brain tumors |
US8178564B2 (en) * | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
US20100310661A1 (en) * | 2007-07-16 | 2010-12-09 | Poniard Pharmaceuticals, Inc. | Oral formulations for picoplatin |
CA2715348A1 (en) * | 2008-02-08 | 2009-08-13 | Poniard Pharmaceuticals, Inc. | Use of picoplatin and bevacizumab to treat colorectal cancer |
TWI492759B (zh) * | 2008-03-05 | 2015-07-21 | Otsuka Pharma Co Ltd | 膽甾烷醇衍生物之併用用途 |
PL2310020T3 (pl) | 2008-07-11 | 2017-10-31 | Univ Texas | Nowe octany 2-deoksymonosacharydów o aktywności przeciwnowotworowej |
KR101106214B1 (ko) * | 2011-04-04 | 2012-01-20 | 홍오성 | 감귤 내껍질 분리 장치 |
EP2981270B1 (en) | 2013-04-05 | 2021-08-25 | Board of Regents, The University of Texas System | Esters of 2-deoxy-monosaccharides with anti proliferative activity |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
JP2002518341A (ja) * | 1998-06-15 | 2002-06-25 | アーチ・デヴェロップメント・コーポレイション | 放射線療法と抗血管形成因子の組み合わせ |
GB9903404D0 (en) | 1999-02-16 | 1999-04-07 | Angiogene Pharm Ltd | Methods of treatment and compositions useful for the treatment of diseases involving angiogenesis |
MXPA02009603A (es) | 2000-03-31 | 2004-05-14 | Angiogene Pharm Ltd | Terapias de dosis divididas con actividad de deterioro vascular. |
-
2001
- 2001-02-27 EE EEP200200565A patent/EE200200565A/xx unknown
- 2001-03-27 KR KR1020027013061A patent/KR20020087456A/ko not_active Application Discontinuation
- 2001-03-27 MX MXPA02009604A patent/MXPA02009604A/es unknown
- 2001-03-27 JP JP2001572111A patent/JP2003528920A/ja active Pending
- 2001-03-27 PT PT01915490T patent/PT1272199E/pt unknown
- 2001-03-27 EP EP01915490A patent/EP1272199B1/en not_active Expired - Lifetime
- 2001-03-27 CN CN01807444A patent/CN1430515A/zh active Pending
- 2001-03-27 WO PCT/GB2001/001317 patent/WO2001074368A1/en not_active Application Discontinuation
- 2001-03-27 CA CA002402539A patent/CA2402539A1/en not_active Abandoned
- 2001-03-27 DE DE60108489T patent/DE60108489T2/de not_active Expired - Fee Related
- 2001-03-27 US US10/240,213 patent/US6906048B2/en not_active Expired - Fee Related
- 2001-03-27 AU AU2001242581A patent/AU2001242581B2/en not_active Ceased
- 2001-03-27 AT AT01915490T patent/ATE287267T1/de not_active IP Right Cessation
- 2001-03-27 NZ NZ521025A patent/NZ521025A/en unknown
- 2001-03-27 HU HU0300290A patent/HUP0300290A3/hu unknown
- 2001-03-27 CZ CZ20023228A patent/CZ20023228A3/cs unknown
- 2001-03-27 BR BR0109672-9A patent/BR0109672A/pt not_active IP Right Cessation
- 2001-03-27 PL PL01366379A patent/PL366379A1/xx not_active Application Discontinuation
- 2001-03-27 IL IL15162801A patent/IL151628A0/xx unknown
- 2001-03-27 SK SK1391-2002A patent/SK13912002A3/sk not_active Application Discontinuation
- 2001-03-27 AU AU4258101A patent/AU4258101A/xx active Pending
- 2001-03-27 ES ES01915490T patent/ES2236199T3/es not_active Expired - Lifetime
-
2002
- 2002-09-20 IS IS6558A patent/IS6558A/is unknown
- 2002-09-27 NO NO20024646A patent/NO20024646L/no unknown
-
2004
- 2004-11-23 US US10/994,639 patent/US20050107346A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1430515A (zh) | 2003-07-16 |
AU2001242581B2 (en) | 2005-03-03 |
ES2236199T3 (es) | 2005-07-16 |
EP1272199A1 (en) | 2003-01-08 |
AU4258101A (en) | 2001-10-15 |
BR0109672A (pt) | 2003-02-04 |
EE200200565A (et) | 2004-06-15 |
EP1272199B1 (en) | 2005-01-19 |
IS6558A (is) | 2002-09-20 |
DE60108489T2 (de) | 2006-03-30 |
NO20024646L (no) | 2002-10-15 |
HUP0300290A3 (en) | 2005-12-28 |
PT1272199E (pt) | 2005-05-31 |
CZ20023228A3 (cs) | 2003-01-15 |
ATE287267T1 (de) | 2005-02-15 |
NZ521025A (en) | 2005-06-24 |
JP2003528920A (ja) | 2003-09-30 |
US20050107346A1 (en) | 2005-05-19 |
KR20020087456A (ko) | 2002-11-22 |
IL151628A0 (en) | 2003-04-10 |
SK13912002A3 (sk) | 2003-05-02 |
DE60108489D1 (de) | 2005-02-24 |
US20030166617A1 (en) | 2003-09-04 |
CA2402539A1 (en) | 2001-10-11 |
NO20024646D0 (no) | 2002-09-27 |
US6906048B2 (en) | 2005-06-14 |
PL366379A1 (en) | 2005-01-24 |
WO2001074368A1 (en) | 2001-10-11 |
MXPA02009604A (es) | 2003-03-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |