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HUP0104853A2 - Liposzómás nifluminsavat tartalmazó, új transzdermális gyulladásgátló gyógyszerkészítmény - Google Patents

Liposzómás nifluminsavat tartalmazó, új transzdermális gyulladásgátló gyógyszerkészítmény

Info

Publication number
HUP0104853A2
HUP0104853A2 HU0104853A HUP0104853A HUP0104853A2 HU P0104853 A2 HUP0104853 A2 HU P0104853A2 HU 0104853 A HU0104853 A HU 0104853A HU P0104853 A HUP0104853 A HU P0104853A HU P0104853 A2 HUP0104853 A2 HU P0104853A2
Authority
HU
Hungary
Prior art keywords
niflumic acid
liposomic
medicine containing
new transdermal
inflammatory medicine
Prior art date
Application number
HU0104853A
Other languages
English (en)
Inventor
Konstantinos Demetzos
Aristidis Georgopoulos
Georgios Giannisis
Sofia Hatziantoniou
Helen Kammenou
Georgios Nounesis
Georgios Papaioannou
Michalis Rallis
Christina Savva-Dimopoulou
Georgios Tsamouris
Original Assignee
P.N. Gerolymatos S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by P.N. Gerolymatos S.A. filed Critical P.N. Gerolymatos S.A.
Publication of HUP0104853A2 publication Critical patent/HUP0104853A2/hu
Publication of HUP0104853A3 publication Critical patent/HUP0104853A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Jelen találmány nifluminsav és származékainak, szintetikus észtereinekliposzómákba való bekapszulázására vonatkozik abból a célból, hogy egyúj transzdermális, nem szteroid gyulladásgátló készítményt hozzanaklétre. A nifluminsavat és ennek észtereit különböző lipidekbőlkészített liposzómákba kapszulázták be, hogy egy növelt hatékonyságúgyógyszerkészítményt kapjanak. A liposzóma-szuszpenziót önmagában éshatóanyaggal töltötten egyaránt előállították kenőcsformában, és avégső összetétellel stabilitásvizsgálatot végeznek. Ó
HU0104853A 1998-12-24 1999-12-22 New transdermal anti-inflammatory medicine containing liposomic niflumic acid HUP0104853A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR98100469 1998-12-24

Publications (2)

Publication Number Publication Date
HUP0104853A2 true HUP0104853A2 (hu) 2002-05-29
HUP0104853A3 HUP0104853A3 (en) 2003-05-28

Family

ID=10943556

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104853A HUP0104853A3 (en) 1998-12-24 1999-12-22 New transdermal anti-inflammatory medicine containing liposomic niflumic acid

Country Status (17)

Country Link
EP (1) EP1140089A1 (hu)
JP (1) JP2002533394A (hu)
KR (1) KR20010089889A (hu)
CN (1) CN1331592A (hu)
AU (1) AU1673400A (hu)
BR (1) BR9917006A (hu)
CA (1) CA2357765A1 (hu)
CZ (1) CZ20012240A3 (hu)
GR (1) GR1003359B (hu)
HU (1) HUP0104853A3 (hu)
IL (1) IL143499A0 (hu)
IS (1) IS5964A (hu)
MX (1) MXPA01006462A (hu)
NO (1) NO20013015L (hu)
PL (1) PL349344A1 (hu)
SK (1) SK7962001A3 (hu)
WO (1) WO2000038681A1 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4874548B2 (ja) * 2002-11-26 2012-02-15 ギリアード サイエンシーズ， インコーポレイテッド 勾配によるリポソームへの薬物充填方法
WO2004096140A2 (en) * 2003-04-25 2004-11-11 The Penn State Research Foundation Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
US20050255154A1 (en) 2004-05-11 2005-11-17 Lena Pereswetoff-Morath Method and composition for treating rhinitis
JP4791082B2 (ja) * 2005-05-30 2011-10-12 株式会社クラレ リポソームおよびそれを含む皮膚外用剤
JP4931369B2 (ja) * 2005-05-31 2012-05-16 ポーラ化成工業株式会社 リポソームおよびそれを含む処置用の組成物
CA2608631C (en) 2005-06-09 2014-07-29 Biolipox Ab Method and composition for treating inflammatory disorders
US20120028335A1 (en) 2010-07-28 2012-02-02 Life Technologies Corporation Anti-viral azide-containing compounds
EP2598128B1 (en) 2010-07-28 2018-03-28 Life Technologies Corporation Anti- viral azide-containing compounds
EP2807252B1 (en) 2012-01-26 2017-05-10 Life Technologies Corporation Methods for increasing the infectivity of viruses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528193A (en) * 1978-12-27 1985-07-09 A. Natterman & Cie. Gmbh Inflammation-preventing pharmaceutical composition of oral administration
DE3683606D1 (de) * 1985-11-27 1992-03-05 Ethicon Inc Hemmung der postoperativen adhaesionsbildung durch topische verabreichung eines entzuendungshemmenden nichtsteroiden wirkstoffs.
DE3778972D1 (de) * 1986-06-12 1992-06-17 Liposome Co Inc Mittel unter verwendung liposomverkapselter, nichtsteroider, antiinflammatorischer arzneistoffe.
DE69632859T2 (de) * 1995-04-18 2005-07-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Verfahren zur Arzneistoffbehandlung von Liposomen Zusammensetzung

Also Published As

Publication number Publication date
BR9917006A (pt) 2001-10-30
AU1673400A (en) 2000-07-31
NO20013015D0 (no) 2001-06-18
CN1331592A (zh) 2002-01-16
HUP0104853A3 (en) 2003-05-28
MXPA01006462A (es) 2002-06-04
GR1003359B (el) 2000-04-10
IS5964A (is) 2001-06-08
PL349344A1 (en) 2002-07-15
NO20013015L (no) 2001-06-18
EP1140089A1 (en) 2001-10-10
KR20010089889A (ko) 2001-10-12
CZ20012240A3 (cs) 2001-11-14
SK7962001A3 (en) 2002-02-05
IL143499A0 (en) 2002-04-21
WO2000038681A1 (en) 2000-07-06
JP2002533394A (ja) 2002-10-08
CA2357765A1 (en) 2000-07-06

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