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HUP0104431A2 - Finoman hangolt protegrinek - Google Patents

Finoman hangolt protegrinek

Info

Publication number
HUP0104431A2
HUP0104431A2 HU0104431A HUP0104431A HUP0104431A2 HU P0104431 A2 HUP0104431 A2 HU P0104431A2 HU 0104431 A HU0104431 A HU 0104431A HU P0104431 A HUP0104431 A HU P0104431A HU P0104431 A2 HUP0104431 A2 HU P0104431A2
Authority
HU
Hungary
Prior art keywords
peptides
protegrins
fine tuned
antimicrobial
aprotegrins
Prior art date
Application number
HU0104431A
Other languages
English (en)
Inventor
Conway C. Chang
Jie Chen
Chee Liang Gu
Robert I. Lehrer
Deborah A. Steinberg
Original Assignee
Intrabiotics Pharmaceuticals, Inc.
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrabiotics Pharmaceuticals, Inc., The Regents Of The University Of California filed Critical Intrabiotics Pharmaceuticals, Inc.
Publication of HUP0104431A2 publication Critical patent/HUP0104431A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)

Abstract

A találmány tárgyát az antimikrobiális peptidek egy új osztálya, aprotegrinek képezik, amiknek jellemző tagjait sertésleukocitákbólizolálták. A protegrin peptidek, amik általában amfifil természetűek,széles spektrumú antimikrobiális aktivitással rendelkeznek. Ezek apeptidek jól használhatók antibakteriális, antifungális és antiviráliságensként mind növényekben, mind állatokban. Ó
HU0104431A 1995-11-22 1996-11-22 Finoman hangolt protegrinek HUP0104431A2 (hu)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56234695A 1995-11-22 1995-11-22
US64981196A 1996-05-17 1996-05-17
US69092196A 1996-08-01 1996-08-01
US08/752,852 US5994306A (en) 1995-11-22 1996-11-21 Fine-tuned protegrins
PCT/US1996/018544 WO1997018826A1 (en) 1995-11-22 1996-11-22 Fine tuned protegrins

Publications (1)

Publication Number Publication Date
HUP0104431A2 true HUP0104431A2 (hu) 2002-03-28

Family

ID=27415886

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104431A HUP0104431A2 (hu) 1995-11-22 1996-11-22 Finoman hangolt protegrinek

Country Status (12)

Country Link
US (1) US5994306A (hu)
EP (1) EP0862448A4 (hu)
JP (1) JP2001520639A (hu)
KR (1) KR19990071546A (hu)
CN (1) CN1251041A (hu)
AU (1) AU720467B2 (hu)
BR (1) BR9611565A (hu)
CZ (1) CZ159198A3 (hu)
HU (1) HUP0104431A2 (hu)
NO (2) NO982310L (hu)
PL (1) PL336763A1 (hu)
WO (2) WO1997018826A1 (hu)

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FR2767323B1 (fr) * 1997-08-12 2001-01-05 Synt Em Peptides lineaires derives de peptides antibiotiques, leur preparation et leur utilisation pour vectoriser des substances actives
US6043220A (en) * 1997-12-03 2000-03-28 Intrabiotics Pharmaceuticals, Inc. Threonine-containing protegrins
KR100314721B1 (ko) * 1998-01-22 2001-11-23 김일웅 생물학적 활성이 있는 신규한 펩타이드
CA2327329A1 (en) * 1998-03-12 1999-09-16 Georgetown University Medical Center Cholesterol recognition sequence
US7223727B2 (en) 1998-04-09 2007-05-29 Serono Genetics Institute S.A. GSSP4 polynucleotides and polypeptides and uses thereof
WO2000000214A2 (en) * 1998-06-26 2000-01-06 N.V. Nutricia Pharmaceutical preparations for use in combatting or preventing surface infections caused by microorganisms
EP0974360A3 (en) * 1998-06-26 2000-03-29 N.V. Nutricia Pharmaceutical preparations for use in combatting or preventing surface infections caused by microorganisms
DK1091774T3 (da) * 1998-07-02 2003-02-24 Stichting Skeletal Tissue Engi Knoglecement med antimikrobielle peptider
AU5006499A (en) * 1998-07-23 2000-02-14 Intrabiotics Pharmaceuticals, Inc. Compositions and methods for the treatment or prevention of pulmonary infections
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
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CA2391356A1 (en) * 1999-12-21 2001-06-28 Innogenetics N.V. Peptides designed for the diagnosis and treatment of rheumatoid arthritis
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GB0031425D0 (en) * 2000-12-22 2001-02-07 Amoebics Ltd Antibacterial treatments
KR100738362B1 (ko) * 2001-03-19 2007-07-12 재단법인서울대학교산학협력재단 신규한 디아민디티올 유도체 및 그의 방사성 레늄 또는방사성 테크네슘 착체； 그리고, 그의 방사성 레늄 착체와리피오돌을 포함하는 간암 치료용 조성물 및 그의 제조용키트
CN1516598A (zh) * 2001-06-22 2004-07-28 ��ͯ����ҽԺ 抗菌肽
US7033991B2 (en) 2001-07-16 2006-04-25 Board Of Supervisors Of Louisiana State University And Agriculture And Mechanical College Inhibiting furin with polybasic peptides
AU2003216091A1 (en) * 2002-01-22 2003-09-02 Intrabiotics Pharmaceuticals, Inc. Hybrid synthetic method for antimicrobial peptides
KR20050016362A (ko) 2002-04-22 2005-02-21 다우 글로벌 테크놀로지스 인크. 펩티드의 저비용 생산
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
US20060148690A1 (en) * 2002-07-08 2006-07-06 Lydie Bougueleret Secreted peptides
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
US7875620B2 (en) * 2005-06-30 2011-01-25 Piper Medical, Inc. Methods of treating microbial infections
WO2008030988A2 (en) 2006-09-06 2008-03-13 The Regents Of The University Of California Selectively targeted antimicrobial peptides and the use thereof
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
CN102088991A (zh) 2008-05-13 2011-06-08 堪萨斯大学 金属提取肽标签和相关方法
TWI394578B (zh) * 2009-01-09 2013-05-01 Academia Sinica 抗菌蛋白之新用途
US20100202983A1 (en) * 2009-02-09 2010-08-12 Jernberg Gary R Selectively targeted antimicrobials for the treatment of periodontal disease
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WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
US9925223B2 (en) 2012-09-25 2018-03-27 Regents Of The University Of Minnesota Methods for making and using antimicrobial peptides
CN103623391B (zh) * 2013-10-10 2014-12-31 中山大学 抗菌肽Protegrin-1在防治猪蓝耳病中的应用
JP2016535770A (ja) 2013-11-01 2016-11-17 スフェリウム バイオメッド エス．エル． 治療用及び美容用物質を経皮送達するための封入体
CN103936827B (zh) * 2014-04-22 2015-10-14 福州大学 一种韭菜籽抗菌三肽及其制备方法与应用
CN105175509A (zh) * 2015-10-19 2015-12-23 河南科技学院 一种抗菌肽xyz-1及其应用
CN108524911B (zh) * 2018-02-27 2022-03-08 成都山信药业有限公司 Protegrin-1抗菌肽衍生物在制备抗口腔致病菌药物中的用途
CN113226349A (zh) * 2018-10-19 2021-08-06 激流生物科学有限公司 抗微生物肽及其使用方法
CN113557027A (zh) 2018-12-28 2021-10-26 普通益生菌股份有限公司 用于治疗胃肠道病原体的工程抗微生物益生菌的联合
US11771694B2 (en) 2020-06-05 2023-10-03 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections
CN113975373A (zh) * 2021-11-18 2022-01-28 宁波市眼科医院 眼用制剂

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Also Published As

Publication number Publication date
NO982311L (no) 1998-07-22
WO1997018827A1 (en) 1997-05-29
EP0862448A1 (en) 1998-09-09
EP0862448A4 (en) 1999-03-31
WO1997018826A1 (en) 1997-05-29
KR19990071546A (ko) 1999-09-27
JP2001520639A (ja) 2001-10-30
NO982311D0 (no) 1998-05-20
AU7739496A (en) 1997-06-11
US5994306A (en) 1999-11-30
CN1251041A (zh) 2000-04-19
PL336763A1 (en) 2000-07-17
BR9611565A (pt) 1999-12-28
NO982310L (no) 1998-07-22
NO982310D0 (no) 1998-05-20
AU720467B2 (en) 2000-06-01
CZ159198A3 (cs) 1998-10-14

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